| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Just like classical chemokine receptors, atypical chemokine receptors (ACKRs) are seven-transmembrane-helix (7TM) receptors that bind chemokines []. However, they lack the canonical DRYLAIV motif necessary for GPCR coupling to G proteins and induction of classical signalling pathways. Instead, ACKRs internalise their chemokine ligands, which may subsequently affect chemokine availability. The ACKR family comprises five members: Duffy Antigen Receptor for Chemokines (DARC, ACKR1), D6 (ACKR2), CXCR7 (ACKR3), CCRL1 (ACKR4) and CCRL2 (ACKR5) [].Atypical chemokine receptor 3 (ACKR3), previously known as CXC chemokine receptor 7 (CXCR7), is regarded as a scavenger for CXCL12 and, to a lesser extent, for CXCL11 []. Unlike other CXC chemokine receptors, ACKR3 does not elicit classical chemokine receptor signalling via typical G protein-mediated pathways [], but instead induces beta-arrestin recruitment, leading to ligand internalisation and activation of MAPK signaling pathway [, ].ACKR3/CXCR7 has been identified on memory B cells and in mammals is found in bone, brain, heart and kidney [, ]. It has been shown to act as a novel coreceptor for several immunodeficiency virus strains, which infect brain-derived cells []. Studies in zebrafish have also revealed a critical role in vascular formation and angiogenesis during development []. ACKR3/CXCR7 is a functional receptor for CXCL12 in astrocytomas/glioblastomas and mediates resistance to drug-induced apoptosis []. It has been shown to promote growth of tumors formed from breast and lung cancer cells []. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gerrits H |
| Year: |
2008 |
| Journal: |
Genesis |
| Title: |
Early postnatal lethality and cardiovascular defects in CXCR7-deficient mice. |
| Volume: |
46 |
| Issue: |
5 |
| Pages: |
235-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Burns JM |
| Year: |
2006 |
| Journal: |
J Exp Med |
| Title: |
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. |
| Volume: |
203 |
| Issue: |
9 |
| Pages: |
2201-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sierro F |
| Year: |
2007 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. |
| Volume: |
104 |
| Issue: |
37 |
| Pages: |
14759-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rohlfing AK |
| Year: |
2022 |
| Journal: |
Nat Commun |
| Title: |
ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
1823 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Saaber F |
| Year: |
2019 |
| Journal: |
Cell Rep |
| Title: |
ACKR3 Regulation of Neuronal Migration Requires ACKR3 Phosphorylation, but Not β-Arrestin. |
| Volume: |
26 |
| Issue: |
6 |
| Pages: |
1473-1488.e9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Radice E |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
Marginal Zone Formation Requires ACKR3 Expression on B Cells. |
| Volume: |
32 |
| Issue: |
5 |
| Pages: |
107951 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Whitman MC |
| Year: |
2019 |
| Journal: |
Hum Mol Genet |
| Title: |
Decreased ACKR3 (CXCR7) function causes oculomotor synkinesis in mice and humans. |
| Volume: |
28 |
| Issue: |
18 |
| Pages: |
3113-3125 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fukuoka A |
| Year: |
2024 |
| Journal: |
Development |
| Title: |
Disruption of placental ACKR3 impairs growth and hematopoietic development of offspring. |
| Volume: |
151 |
| Issue: |
4 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sigmund EC |
| Year: |
2021 |
| Journal: |
PLoS One |
| Title: |
Lymphatic endothelial-cell expressed ACKR3 is dispensable for postnatal lymphangiogenesis and lymphatic drainage function in mice. |
| Volume: |
16 |
| Issue: |
4 |
| Pages: |
e0249068 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Venkataramanappa S |
| Year: |
2022 |
| Journal: |
Cell Rep |
| Title: |
Cxcr4 and Ackr3 regulate allocation of caudal ganglionic eminence-derived interneurons to superficial cortical layers. |
| Volume: |
40 |
| Issue: |
5 |
| Pages: |
111157 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Naumann U |
| Year: |
2010 |
| Journal: |
PLoS One |
| Title: |
CXCR7 functions as a scavenger for CXCL12 and CXCL11. |
| Volume: |
5 |
| Issue: |
2 |
| Pages: |
e9175 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shimizu N |
| Year: |
2000 |
| Journal: |
J Virol |
| Title: |
A putative G protein-coupled receptor, RDC1, is a novel coreceptor for human and simian immunodeficiency viruses. |
| Volume: |
74 |
| Issue: |
2 |
| Pages: |
619-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rajagopal S |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7. |
| Volume: |
107 |
| Issue: |
2 |
| Pages: |
628-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hattermann K |
| Year: |
2010 |
| Journal: |
Cancer Res |
| Title: |
The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects. |
| Volume: |
70 |
| Issue: |
8 |
| Pages: |
3299-308 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miao Z |
| Year: |
2007 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature. |
| Volume: |
104 |
| Issue: |
40 |
| Pages: |
15735-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zabel BA |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands. |
| Volume: |
183 |
| Issue: |
5 |
| Pages: |
3204-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nibbs RJ |
| Year: |
2013 |
| Journal: |
Nat Rev Immunol |
| Title: |
Immune regulation by atypical chemokine receptors. |
| Volume: |
13 |
| Issue: |
11 |
| Pages: |
815-29 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bachelerie F |
| Year: |
2014 |
| Journal: |
Nat Immunol |
| Title: |
New nomenclature for atypical chemokine receptors. |
| Volume: |
15 |
| Issue: |
3 |
| Pages: |
207-8 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
362
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6714315 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-06-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270423 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:6715221 |
| Age: |
embryonic day 15.5 |
|
| Note: |
The majority of interneurons in the subventricular zone/intermediate zone expressed both Ackr3 and Cxcr4 (57.7%), and 21% expressed only Ackr3. |
| Specimen Label: |
3C |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6714315 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-06-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:6715221 |
| Age: |
embryonic day 15.5 |
|
| Note: |
The vast majority of interneurons in the cortical plate expressed both Ackr3 and Cxcr4 (47.5%) or Ackr3 alone (45.1%). |
| Specimen Label: |
not shown |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6714315 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-06-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271223 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:6715221 |
| Age: |
embryonic day 15.5 |
|
| Note: |
The majority of interneurons in the subventricular zone/intermediate zone expressed both Ackr3 and Cxcr4 (57.7%), and 21% expressed only Ackr3. |
| Specimen Label: |
3C |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6714315 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-06-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:6715221 |
| Age: |
embryonic day 15.5 |
|
| Note: |
More than 75% of all interneurons co-expressed Ackr3 and Cxcr4, and 17% expressed Ackr3 alone in the marginal zone. |
| Specimen Label: |
not shown |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6714315 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-06-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270423 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:6715221 |
| Age: |
embryonic day 15.5 |
|
| Note: |
Ackr3-positive cells in the subventricular zone co-expressed Lhx6, a marker of cortical interneurons. Ackr3 was expressed in about 50% of interneurons migrating in the subventricular zone. |
| Specimen Label: |
3A SVZ |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6714315 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-06-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:6715221 |
| Age: |
embryonic day 15.5 |
|
| Note: |
Ackr3-positive cells in the marginal zone co-expressed Lhx6, a marker of cortical interneurons. Ackr3 was expressed in the majority of interneurons migrating in the marginal zone (73.5%). |
| Specimen Label: |
3A MZ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6714315 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-06-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754421 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:6715141 |
| Age: |
embryonic day 13.5 |
|
| Note: |
At E13.5, this segment of the cerebral cortex showed no expression of Ackr3 in the Reln-positive Cajal-Retzius cells. However, the medial part of the cerebral cortex did show expression. |
| Specimen Label: |
2B' |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fumagalli A |
| Year: |
2020 |
| Journal: |
Nat Commun |
| Title: |
The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
4855 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ehrlich AT |
| Year: |
2021 |
| Journal: |
Mol Brain |
| Title: |
Ackr3-Venus knock-in mouse lights up brain vasculature. |
| Volume: |
14 |
| Issue: |
1 |
| Pages: |
151 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Quinn KE |
| Year: |
2020 |
| Journal: |
Placenta |
| Title: |
Deletion of atypical chemokine receptor 3 (ACKR3) increases immune cells at the fetal-maternal interface. |
| Volume: |
95 |
|
| Pages: |
18-25 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Littman DR |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Generation of a Cxcr7 reporter allele |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Berahovich RD |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
CXCR7 protein is not expressed on human or mouse leukocytes. |
| Volume: |
185 |
| Issue: |
9 |
| Pages: |
5130-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hao H |
| Year: |
2017 |
| Journal: |
Circulation |
| Title: |
Loss of Endothelial CXCR7 Impairs Vascular Homeostasis and Cardiac Remodeling After Myocardial Infarction: Implications for Cardiovascular Drug Discovery. |
| Volume: |
135 |
| Issue: |
13 |
| Pages: |
1253-1264 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cruz-Orengo L |
| Year: |
2011 |
| Journal: |
J Exp Med |
| Title: |
CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity. |
| Volume: |
208 |
| Issue: |
2 |
| Pages: |
327-39 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Williams JL |
| Year: |
2014 |
| Journal: |
J Exp Med |
| Title: |
Targeting CXCR7/ACKR3 as a therapeutic strategy to promote remyelination in the adult central nervous system. |
| Volume: |
211 |
| Issue: |
5 |
| Pages: |
791-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Banisadr G |
| Year: |
2016 |
| Journal: |
J Neuroimmune Pharmacol |
| Title: |
Pattern of CXCR7 Gene Expression in Mouse Brain Under Normal and Inflammatory Conditions. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
26-35 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Monnier J |
| Year: |
2012 |
| Journal: |
Eur J Cancer |
| Title: |
CXCR7 is up-regulated in human and murine hepatocellular carcinoma and is specifically expressed by endothelial cells. |
| Volume: |
48 |
| Issue: |
1 |
| Pages: |
138-48 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ikeda Y |
| Year: |
2013 |
| Journal: |
Cell |
| Title: |
Modulation of circadian glucocorticoid oscillation via adrenal opioid-CXCR7 signaling alters emotional behavior. |
| Volume: |
155 |
| Issue: |
6 |
| Pages: |
1323-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bao J |
| Year: |
2016 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
CXCR7 suppression modulates microglial chemotaxis to ameliorate experimentally-induced autoimmune encephalomyelitis. |
| Volume: |
469 |
| Issue: |
1 |
| Pages: |
1-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Peng H |
| Year: |
2016 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Blocking CXCR7-mediated adipose tissue macrophages chemotaxis attenuates insulin resistance and inflammation in obesity. |
| Volume: |
479 |
| Issue: |
4 |
| Pages: |
649-655 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ngamsri KC |
| Year: |
2017 |
| Journal: |
J Immunol |
| Title: |
The Pivotal Role of CXCR7 in Stabilization of the Pulmonary Epithelial Barrier in Acute Pulmonary Inflammation. |
| Volume: |
198 |
| Issue: |
6 |
| Pages: |
2403-2413 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stacer AC |
| Year: |
2016 |
| Journal: |
Oncogene |
| Title: |
Endothelial CXCR7 regulates breast cancer metastasis. |
| Volume: |
35 |
| Issue: |
13 |
| Pages: |
1716-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim N |
| Year: |
2019 |
| Journal: |
Sci Rep |
| Title: |
CXCR7 promotes migration and invasion in head and neck squamous cell carcinoma by upregulating TGF-β1/Smad2/3 signaling. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
18100 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3760387 |
| Age: |
postnatal |
| Image: |
4 |
|
| Specimen Label: |
Heart |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3760387 |
| Age: |
postnatal |
| Image: |
4 |
|
| Specimen Label: |
Brain |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3760387 |
| Age: |
postnatal |
| Image: |
4 |
|
| Specimen Label: |
Liver |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3760387 |
| Age: |
postnatal |
| Image: |
4 |
|
| Specimen Label: |
Spleen |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3760387 |
| Age: |
postnatal |
| Image: |
4 |
|
| Specimen Label: |
Kidney |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603922 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:3760387 |
| Age: |
embryonic day 14.0 |
| Image: |
4 |
|
| Specimen Label: |
Embryo d14 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3760387 |
| Age: |
postnatal |
| Image: |
4 |
|
| Specimen Label: |
Lung |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3760387 |
| Age: |
postnatal |
| Image: |
4 |
|
| Specimen Label: |
Thymus |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-06 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3760387 |
| Age: |
postnatal |
| Image: |
4 |
|
| Specimen Label: |
Testis |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-06 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3760387 |
| Age: |
postnatal |
| Image: |
4 |
|
| Specimen Label: |
Ovary |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684618 |
|
| Stage: |
TS18 |
| Assay Id: |
MGI:3760514 |
| Age: |
embryonic day 11.0 |
| Image: |
5 |
|
| Specimen Label: |
E11 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684621 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:3760514 |
| Age: |
embryonic day 13.0 |
| Image: |
5 |
|
| Specimen Label: |
E13 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-07 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684623 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:3760514 |
| Age: |
embryonic day 15.0 |
| Image: |
5 |
|
| Specimen Label: |
E15 |
| Detected: |
false |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3760385 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2007-11-07 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684625 |
|
| Stage: |
TS25 |
| Assay Id: |
MGI:3760514 |
| Age: |
embryonic day 17.0 |
| Image: |
5 |
|
| Specimen Label: |
E17 |
| Detected: |
false |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5001207 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-02-07 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:2914821 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:5541763 |
| Age: |
embryonic day 13.5 |
| Image: |
GUDMAP:9564 |
|
| Specimen Label: |
GUDMAP:9564 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6714315 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-06-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270421 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:6715130 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Expression was detected in the lateral cortex. |
| Specimen Label: |
1C |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6714315 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-06-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270423 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:6715130 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
1D |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6714315 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-06-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270427 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:6715130 |
| Age: |
postnatal day 2 |
|
|
| Specimen Label: |
4A |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884073 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691619 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:4945957 |
| Age: |
embryonic day 11.5 |
| Image: |
g02341 E11.5 |
| Note: |
Expression was region specific and scattered. |
| Specimen Label: |
g02341 E11.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884073 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691623 |
| Pattern: |
Scattered |
| Stage: |
TS23 |
| Assay Id: |
MGI:4945957 |
| Age: |
embryonic day 15.5 |
| Image: |
g02341 E15.5 |
|
| Specimen Label: |
g02341 E15.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5576569 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-08-08 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691617 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:5576571 |
| Age: |
embryonic day 10.5 |
| Image: |
1A |
|
| Specimen Label: |
1A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5001207 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-02-07 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797021 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:5541763 |
| Age: |
embryonic day 13.5 |
| Image: |
GUDMAP:9564 |
|
| Specimen Label: |
GUDMAP:9564 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5001207 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-02-07 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1737321 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:5541763 |
| Age: |
embryonic day 13.5 |
| Image: |
GUDMAP:9565 |
|
| Specimen Label: |
GUDMAP:9565 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884073 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284223 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4945957 |
| Age: |
embryonic day 15.5 |
| Image: |
g02341 E15.5 |
| Note: |
Expression was region specific and scattered. |
| Specimen Label: |
g02341 E15.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5576569 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-08-08 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689517 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5576571 |
| Age: |
embryonic day 10.5 |
| Image: |
1A |
|
| Specimen Label: |
1A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884073 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3267828 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945957 |
| Age: |
postnatal day 7 |
| Image: |
g02341 P7 |
|
| Specimen Label: |
g02341 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884073 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3267828 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945957 |
| Age: |
postnatal day 42 |
| Image: |
g02341 Adult |
|
| Specimen Label: |
g02341 Adult |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6714315 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-06-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754927 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:6715130 |
| Age: |
postnatal day 2 |
|
| Note: |
Expression was detected in the striatal subventricular zone. |
| Specimen Label: |
1E |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7464335 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-04-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754923 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:7464534 |
| Age: |
embryonic day 15.5 |
| Image: |
6s |
|
| Specimen Label: |
6s |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7464335 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-04-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754923 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:7464534 |
| Age: |
embryonic day 15.5 |
| Image: |
6s' |
| Note: |
Expression was maintained or slightly increased in the striatum. |
| Specimen Label: |
6s' |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|