| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-11-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3660822 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7382874 |
| Age: |
embryonic day 14.5 |
|
| Note: |
GFP and Aif1 expression co-localized in choroid plexus macrophages. |
| Specimen Label: |
3f Choroid plexus Cx3cr1 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-11-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3660922 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7382874 |
| Age: |
embryonic day 14.5 |
|
| Note: |
GFP and Aif1 expression co-localized in choroid plexus macrophages. |
| Specimen Label: |
3f Choroid plexus Cx3cr1 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-11-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266022 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7382874 |
| Age: |
embryonic day 14.5 |
|
| Note: |
GFP and Aif1 expression co-localized in meningeal macrophages. |
| Specimen Label: |
3f Meninges Cx3cr1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
147
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chinnasamy P |
| Year: |
2023 |
| Journal: |
Nat Commun |
| Title: |
Increased adipose catecholamine levels and protection from obesity with loss of Allograft Inflammatory Factor-1. |
| Volume: |
14 |
| Issue: |
1 |
| Pages: |
38 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pozner A |
| Year: |
2015 |
| Journal: |
Front Mol Neurosci |
| Title: |
Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse. |
| Volume: |
8 |
|
| Pages: |
12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakayama H |
| Year: |
2018 |
| Journal: |
Nat Commun |
| Title: |
Microglia permit climbing fiber elimination by promoting GABAergic inhibition in the developing cerebellum. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
2830 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kishikawa S |
| Year: |
2017 |
| Journal: |
Nat Commun |
| Title: |
Allograft inflammatory factor 1 is a regulator of transcytosis in M cells. |
| Volume: |
8 |
|
| Pages: |
14509 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Egaña-Gorroño L |
| Year: |
2019 |
| Journal: |
Atherosclerosis |
| Title: |
Allograft inflammatory factor-1 supports macrophage survival and efferocytosis and limits necrosis in atherosclerotic plaques. |
| Volume: |
289 |
|
| Pages: |
184-194 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Elizondo DM |
| Year: |
2019 |
| Journal: |
J Leukoc Biol |
| Title: |
IL-10 producing CD8+ CD122+ PD-1+ regulatory T cells are expanded by dendritic cells silenced for Allograft Inflammatory Factor-1. |
| Volume: |
105 |
| Issue: |
1 |
| Pages: |
123-130 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Redmon SN |
| Year: |
2021 |
| Journal: |
Glia |
| Title: |
TRPV4 channels mediate the mechanoresponse in retinal microglia. |
| Volume: |
69 |
| Issue: |
6 |
| Pages: |
1563-1582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nagarajan N |
| Year: |
2024 |
| Journal: |
Mol Psychiatry |
| Title: |
Optogenetic stimulation of mouse Hoxb8 microglia in specific regions of the brain induces anxiety, grooming, or both. |
| Volume: |
29 |
| Issue: |
6 |
| Pages: |
1726-1740 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Watano K |
| Year: |
2001 |
| Journal: |
Immunology |
| Title: |
Allograft inflammatory factor-1 augments production of interleukin-6, -10 and -12 by a mouse macrophage line. |
| Volume: |
104 |
| Issue: |
3 |
| Pages: |
307-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sasaki Y |
| Year: |
2001 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Iba1 is an actin-cross-linking protein in macrophages/microglia. |
| Volume: |
286 |
| Issue: |
2 |
| Pages: |
292-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamada M |
| Year: |
2006 |
| Journal: |
J Mol Biol |
| Title: |
X-ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding. |
| Volume: |
364 |
| Issue: |
3 |
| Pages: |
449-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Casimiro I |
| Year: |
2013 |
| Journal: |
Genesis |
| Title: |
Genetic inactivation of the allograft inflammatory factor-1 locus. |
| Volume: |
51 |
| Issue: |
10 |
| Pages: |
734-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lituma PJ |
| Year: |
2021 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Altered synaptic connectivity and brain function in mice lacking microglial adapter protein Iba1. |
| Volume: |
118 |
| Issue: |
46 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chinnasamy P |
| Year: |
2015 |
| Journal: |
Mol Med |
| Title: |
Loss of Allograft Inflammatory Factor-1 Ameliorates Experimental Autoimmune Encephalomyelitis by Limiting Encephalitogenic CD4 T-Cell Expansion. |
| Volume: |
21 |
| Issue: |
1 |
| Pages: |
233-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Deininger MH |
| Year: |
2002 |
| Journal: |
FEBS Lett |
| Title: |
The allograft inflammatory factor-1 family of proteins. |
| Volume: |
514 |
| Issue: |
2-3 |
| Pages: |
115-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Müller WE |
| Year: |
2002 |
| Journal: |
Immunogenetics |
| Title: |
Histocompatibility reaction in tissue and cells of the marine sponge Suberites domuncula in vitro and in vivo: central role of the allograft inflammatory factor 1. |
| Volume: |
54 |
| Issue: |
1 |
| Pages: |
48-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huysentruyt LC |
| Year: |
2008 |
| Journal: |
Int J Cancer |
| Title: |
Metastatic cancer cells with macrophage properties: evidence from a new murine tumor model. |
| Volume: |
123 |
| Issue: |
1 |
| Pages: |
73-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ziehn MO |
| Year: |
2012 |
| Journal: |
Lab Invest |
| Title: |
Estriol preserves synaptic transmission in the hippocampus during autoimmune demyelinating disease. |
| Volume: |
92 |
| Issue: |
8 |
| Pages: |
1234-45 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6162665 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-06-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6162676 |
| Age: |
postnatal adult |
| Image: |
4D |
| Note: |
Expressed in microglia. |
| Specimen Label: |
4D |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6386249 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-10-30 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270424 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:7544053 |
| Age: |
embryonic day 16.5 |
|
| Note: |
Expression preferentially clustered in ventricular/subventricular zone. |
| Specimen Label: |
E16.5 not shown |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6386249 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-10-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270424 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:7544053 |
| Age: |
embryonic day 16.5 |
| Image: |
2F fl/fl |
|
| Specimen Label: |
2F fl/fl |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6386249 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-10-30 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270424 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:7544053 |
| Age: |
embryonic day 16.5 |
| Image: |
2F cKO |
| Note: |
Increase in number of microglia in ventricular/subventricular zone compared to control. |
| Specimen Label: |
2F cKO |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6386249 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-10-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270424 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:7544053 |
| Age: |
embryonic day 16.5 |
| Image: |
2H cKO |
| Note: |
Contact between microglia and neural progenitor cells in ventricular/subventricular zone was enhancedcompared to control. |
| Specimen Label: |
2H cKO |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-02-21 |
| Strength: |
Trace |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284227 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:7595951 |
| Age: |
postnatal day 2 |
|
| Note: |
Increased expressing cells not observed in control. |
| Specimen Label: |
3D Ctrl |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-02-21 |
| Strength: |
Trace |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284227 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:7595951 |
| Age: |
postnatal day 2 |
|
|
| Specimen Label: |
3D Het |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-02-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284227 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:7595951 |
| Age: |
postnatal day 2 |
|
| Note: |
10-fold increased in expressing cells compared to control. |
| Specimen Label: |
3D cKO |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-02-21 |
| Strength: |
Trace |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7595951 |
| Age: |
postnatal day 7 |
|
|
| Specimen Label: |
P7 Ctrl not shown |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-02-21 |
| Strength: |
Trace |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7595951 |
| Age: |
postnatal day 7 |
|
|
| Specimen Label: |
P7 Het not shown |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-02-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7595951 |
| Age: |
postnatal day 7 |
|
| Note: |
Number of expressing cells significantly increased compared to both other genotypes. |
| Specimen Label: |
P7 cKO not shown |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-11-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266228 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:7382873 |
| Age: |
postnatal |
|
| Note: |
Expression was detected in subdural meninges. |
| Specimen Label: |
1a left |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-11-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7382873 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
6c Meninges WT |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-11-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7382873 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
S4a WT Meninges |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-04-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7451199 |
| Age: |
postnatal |
| Image: |
S9b - meningeal |
|
| Specimen Label: |
S9b - meningeal |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-12-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1729723 |
| Pattern: |
Single cells |
| Stage: |
TS23 |
| Assay Id: |
MGI:6828891 |
| Age: |
embryonic day 15.5 |
| Image: |
5a |
| Note: |
Expression is seen in macrophages. |
| Specimen Label: |
5a |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3581020 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2005-07-08 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3267828 |
| Pattern: |
Single cells |
| Stage: |
TS28 |
| Assay Id: |
MGI:3581056 |
| Age: |
postnatal week 15 |
|
| Note: |
Expression is in microglial cells. |
| Specimen Label: |
4(e) |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3581020 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2005-07-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3267828 |
| Pattern: |
Single cells |
| Stage: |
TS28 |
| Assay Id: |
MGI:3581057 |
| Age: |
postnatal week 15 |
|
| Note: |
Expression is in microglial cells. |
| Specimen Label: |
4(b) |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-06-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754928 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7281813 |
| Age: |
postnatal day 10 |
| Image: |
S9B lower panel |
|
| Specimen Label: |
S9B lower panel |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-06-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754928 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7281813 |
| Age: |
postnatal day 10 |
| Image: |
S9E lower panel |
| Note: |
No differences in Aif1+ microglial cell numbers were noted in the mutant. |
| Specimen Label: |
S9E lower panel |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-06-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1697422 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7281813 |
| Age: |
embryonic day 14.5 |
| Image: |
3L |
|
| Specimen Label: |
3L |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-06-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1697422 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7281813 |
| Age: |
embryonic day 14.5 |
| Image: |
3M |
| Note: |
The Pecam+ blood vessels have abnormal morphologies and show increased juxtaposition with Aif1+ microglia. |
| Specimen Label: |
3M |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-06-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1697422 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7281813 |
| Age: |
embryonic day 14.5 |
| Image: |
3N |
| Note: |
The Pecam+ blood vessels have abnormal morphologies and show increased juxtaposition with Aif1+ microglia. |
| Specimen Label: |
3N |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-06-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1697426 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:7281813 |
| Age: |
embryonic day 18.5 |
| Image: |
S5D midbrain |
|
| Specimen Label: |
S5D midbrain |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-06-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1697426 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:7281813 |
| Age: |
embryonic day 18.5 |
| Image: |
S5E midbrain |
|
| Specimen Label: |
S5E midbrain |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-06-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1697426 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:7281813 |
| Age: |
embryonic day 18.5 |
| Image: |
S5F midbrain |
|
| Specimen Label: |
S5F midbrain |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-04-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3525728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5633994 |
| Age: |
postnatal day 7 |
| Image: |
5B upper Cerebral cortex |
| Note: |
Expressed in microglial cells. |
| Specimen Label: |
5B upper Cerebral cortex |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-04-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3525728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5633995 |
| Age: |
postnatal day 7 |
| Image: |
5C upper Cerebral cortex |
| Note: |
Expressed in microglial cells. |
| Specimen Label: |
5C upper Cerebral cortex |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6478195 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-08 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3583528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6478316 |
| Age: |
postnatal month 10 |
| Image: |
5g 10 months +/+ |
|
| Specimen Label: |
5g 10 months +/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6478195 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-08 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3583528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6478316 |
| Age: |
postnatal month 10 |
| Image: |
5g 10 months -/- |
|
| Specimen Label: |
5g 10 months -/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6478195 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-08 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3583528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6478316 |
| Age: |
postnatal month 13 |
| Image: |
5g 13 months +/+ |
|
| Specimen Label: |
5g 13 months +/+ |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6478195 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-08 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3583528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6478316 |
| Age: |
postnatal month 10 |
| Image: |
5g 10 months +/+ right |
|
| Specimen Label: |
5g 10 months +/+ right |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6478195 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-08 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3583528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6478316 |
| Age: |
postnatal month 10 |
| Image: |
5g 10 months -/- right |
|
| Specimen Label: |
5g 10 months -/- right |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6478195 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-08 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3583528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6478316 |
| Age: |
postnatal month 13 |
| Image: |
5g 13 months +/+ right |
|
| Specimen Label: |
5g 13 months +/+ right |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6478195 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-08 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3583528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6478316 |
| Age: |
postnatal month 13 |
| Image: |
5g 13 months -/- right |
|
| Specimen Label: |
5g 13 months -/- right |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6478195 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-08 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3583528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6478316 |
| Age: |
postnatal month 13 |
| Image: |
5g Resting |
|
| Specimen Label: |
5g Resting |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6478195 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-08 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3583528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6478316 |
| Age: |
postnatal month 13 |
| Image: |
5g Reactive |
|
| Specimen Label: |
5g Reactive |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6478195 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-08 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3583528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6478316 |
| Age: |
postnatal month 13 |
| Image: |
5g 13 months -/- |
|
| Specimen Label: |
5g 13 months -/- |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6478195 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-12-08 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3583528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6478316 |
| Age: |
postnatal month 13 |
| Image: |
5g Dystrophic |
| Note: |
The number of positive dystrophic microglia has increased in this mutant compared to age-matched controls. |
| Specimen Label: |
5g Dystrophic |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3581020 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2014-05-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5565307 |
| Age: |
postnatal day 5 |
| Image: |
4M |
| Note: |
Expressed in microglia. |
| Specimen Label: |
4M |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-07-17 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716828 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:7507606 |
| Age: |
postnatal day 14 |
|
| Note: |
Expression normally in inner eye. |
| Specimen Label: |
not shown |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-07-17 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7507606 |
| Age: |
postnatal day 14 |
| Image: |
6C WT |
|
| Specimen Label: |
6C WT |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-07-17 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7507606 |
| Age: |
postnatal day 14 |
| Image: |
6C KO |
| Note: |
Expressing cels appear rounder and less ramified compared with wild type, indicative of an activated state. |
| Specimen Label: |
6C KO |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-02-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271123 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:7595951 |
| Age: |
embryonic day 15.5 |
|
| Note: |
Levels within cortical plate and intermediate zone remained unchanged compared to control. |
| Specimen Label: |
3A cKO |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7595883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-02-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271223 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:7595951 |
| Age: |
embryonic day 15.5 |
|
| Note: |
Levels within cortical plate and intermediate zone remained unchanged compared to control. |
| Specimen Label: |
3A cKO |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-11-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3660828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7382873 |
| Age: |
postnatal |
|
|
| Specimen Label: |
1a right |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-11-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3660828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7382873 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
6c Choroid plexus WT |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-11-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3660828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7382873 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
S4a WT Choroid plexus |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-11-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3660822 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7382874 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Choroid plexus macrophages were not affected in the Irf8 mutant background. |
| Specimen Label: |
3f Choroid plexus Irf8<-/->;Cx3cr1 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-11-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3660828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7382874 |
| Age: |
postnatal |
|
|
| Specimen Label: |
6b Choroid plexus |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5620494 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-11-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3660828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7382873 |
| Age: |
postnatal adult |
|
| Note: |
Choroid plexus macrophages were reduced in the Ccr2-deficient mice. |
| Specimen Label: |
6c Choroid plexus Ccr2-/- |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6766394 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-10-12 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3514228 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6766569 |
| Age: |
postnatal week 12 |
|
| Note: |
Expression is seen in microglia. |
| Specimen Label: |
S1p |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|