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Search results 1 to 100 out of 4757 for Apoe

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Hits by Strain

Type Details Score
Gene
348 | APOE
Type: gene
Organism: human
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Gene
394678 | apoe
Type: gene
Organism: frog, western clawed
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Gene
key_80147 | APOE
Type: gene
Organism: rabbit, European
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Gene
25728 | Apoe
Type: gene
Organism: rat
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Gene
449586 | APOE
Type: gene
Organism: chimpanzee
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Gene
476438 | APOE
Type: gene
Organism: dog, domestic
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Gene
281004 | APOE
Type: gene
Organism: cattle
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Gene
397576 | APOE
Type: gene
Organism: pig, domestic
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Gene
714623 | APOE
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:88057 | Apoe
Type: protein_coding_gene
Organism: mouse, laboratory
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Strain
MGI:4838569 | B6.129P2-Apoe<tm1Unc>/Tac
Attribute String: congenic, mutant strain, targeted mutation
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Publication
9169506 | J:40921
First Author: Gupta S
Year: 1997
Journal: J Clin Invest
Title: IFN-gamma potentiates atherosclerosis in ApoE knock-out mice.
Volume: 99
Issue: 11
Pages: 2752-61
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Publication
15033273 | J:89344
First Author: Nathan BP
Year: 2004
Journal: Behav Brain Res
Title: Olfactory function in apoE knockout mice.
Volume: 150
Issue: 1-2
Pages: 1-7
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Publication
34085350 | J:311427
First Author: Okutsu M
Year: 2021
Journal: FASEB J
Title: Regular exercise stimulates endothelium autophagy via IL-1 signaling in ApoE deficient mice.
Volume: 35
Issue: 7
Pages: e21698
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Publication
38439966 | J:348937
First Author: Tan J
Year: 2024
Journal: iScience
Title: ApoE maintains neuronal integrity via microRNA and H3K27me3-mediated repression.
Volume: 27
Issue: 3
Pages: 109231
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Protein
Q4FK40
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
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Publication
35115575 | J:322538
First Author: Zajac DJ
Year: 2022
Journal: Sci Rep
Title: APOE genetics influence murine gut microbiome.
Volume: 12
Issue: 1
Pages: 1906
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Publication
27015743 | J:231754
First Author: Getz GS
Year: 2016
Journal: J Lipid Res
Title: ApoE knockout and knockin mice: the history of their contribution to the understanding of atherogenesis.
Volume: 57
Issue: 5
Pages: 758-66
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Publication
17130485 | J:121013
First Author: Huang ZH
Year: 2006
Journal: Diabetes
Title: Endogenous ApoE expression modulates adipocyte triglyceride content and turnover.
Volume: 55
Issue: 12
Pages: 3394-402
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Publication
11120928 | J:66879
First Author: Burnett MS
Year: 2001
Journal: J Infect Dis
Title: Atherosclerosis in apoE knockout mice infected with multiple pathogens.
Volume: 183
Issue: 2
Pages: 226-231
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Publication
10487844 | J:57495
First Author: Licastro F
Year: 1999
Journal: Am J Pathol
Title: A role for apoE in regulating the levels of alpha-1-antichymotrypsin in the aging mouse brain and in Alzheimer's disease.
Volume: 155
Issue: 3
Pages: 869-75
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Publication
33503410 | J:306696
First Author: Li X
Year: 2021
Journal: Neuron
Title: Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Volume: 109
Issue: 6
Pages: 957-970.e8
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Publication
22883220 | J:203252
First Author: Olsen RH
Year: 2012
Journal: Genes Brain Behav
Title: ApoE isoform-dependent deficits in extinction of contextual fear conditioning.
Volume: 11
Issue: 7
Pages: 806-12
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Publication
25092803 | J:216208
First Author: Cudaback E
Year: 2015
Journal: Glia
Title: APOE genotype-dependent modulation of astrocyte chemokine CCL3 production.
Volume: 63
Issue: 1
Pages: 51-65
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Publication
17299204 | J:121848
First Author: Yancey PG
Year: 2007
Journal: J Lipid Res
Title: Severely altered cholesterol homeostasis in macrophages lacking apoE and SR-BI.
Volume: 48
Issue: 5
Pages: 1140-9
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Publication
9266610 | J:127860
First Author: Anderson R
Year: 1997
Journal: Psychopharmacology (Berl)
Title: Absence of central cholinergic deficits in ApoE knockout mice.
Volume: 132
Issue: 2
Pages: 135-44
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Publication
18155324 | J:152961
First Author: Vitek MP
Year: 2009
Journal: Neurobiol Aging
Title: APOE genotype-specific differences in the innate immune response.
Volume: 30
Issue: 9
Pages: 1350-60
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Publication
30079373 | J:266781
 
First Author: Tensaouti Y
Year: 2018
Journal: eNeuro
Title: ApoE Regulates the Development of Adult Newborn Hippocampal Neurons.
Volume: 5
Issue: 4
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Publication
26592663 | J:233188
First Author: Liu M
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice.
Volume: 469
Issue: 3
Pages: 456-62
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Publication
33663537 | J:319502
First Author: Wu H
Year: 2021
Journal: J Transl Med
Title: Lipoprotein glomerulopathy induced by ApoE Kyoto mutation in ApoE-deficient mice.
Volume: 19
Issue: 1
Pages: 97
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Publication
23071294 | J:190990
First Author: Huang ZH
Year: 2013
Journal: J Lipid Res
Title: ApoE derived from adipose tissue does not suppress atherosclerosis or correct hyperlipidemia in apoE knockout mice.
Volume: 54
Issue: 1
Pages: 202-13
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Publication
17669363 | J:124271
First Author: Tennert C
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Effect of macrophage ApoE on atherosclerosis in LDL-receptor deficient mice.
Volume: 361
Issue: 3
Pages: 574-9
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Publication
36130725 | J:340480
First Author: Ostendorf BN
Year: 2022
Journal: Nature
Title: Common human genetic variants of APOE impact murine COVID-19 mortality.
Volume: 611
Issue: 7935
Pages: 346-351
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Publication
19553347 | J:152103
First Author: Arora S
Year: 2009
Journal: Am J Physiol Renal Physiol
Title: Human immunodeficiency virus downregulates podocyte apoE expression.
Volume: 297
Issue: 3
Pages: F653-61
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Publication
18325838 | J:133606
First Author: Ma Z
Year: 2008
Journal: Clin Immunol
Title: Accelerated atherosclerosis in ApoE deficient lupus mouse models.
Volume: 127
Issue: 2
Pages: 168-75
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Publication
26446211 | J:226468
First Author: Levy O
Year: 2015
Journal: J Neurosci
Title: APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration.
Volume: 35
Issue: 40
Pages: 13568-76
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Publication
30692699 | J:338091
First Author: Yin C
Year: 2019
Journal: Nat Med
Title: ApoE attenuates unresolvable inflammation by complex formation with activated C1q.
Volume: 25
Issue: 3
Pages: 496-506
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Publication
16190879 | J:102888
First Author: Levi O
Year: 2005
Journal: J Neurochem
Title: Regulation of hippocampal cholesterol metabolism by apoE and environmental stimulation.
Volume: 95
Issue: 4
Pages: 987-97
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Publication
21478199 | J:171975
First Author: Comley LH
Year: 2011
Journal: Hum Mol Genet
Title: ApoE isoform-specific regulation of regeneration in the peripheral nervous system.
Volume: 20
Issue: 12
Pages: 2406-21
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Publication
23892237 | J:203135
First Author: Yu CE
Year: 2013
Journal: Hum Mol Genet
Title: Epigenetic signature and enhancer activity of the human APOE gene.
Volume: 22
Issue: 24
Pages: 5036-47
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Publication
22862561 | J:190575
First Author: Dumanis SB
Year: 2013
Journal: J Neurochem
Title: APOE genotype affects the pre-synaptic compartment of glutamatergic nerve terminals.
Volume: 124
Issue: 1
Pages: 4-14
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Publication
18987181 | J:143204
First Author: Riddell DR
Year: 2008
Journal: J Neurosci
Title: Impact of apolipoprotein E (ApoE) polymorphism on brain ApoE levels.
Volume: 28
Issue: 45
Pages: 11445-53
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Publication
24069197 | J:207538
First Author: Shin IJ
Year: 2013
Journal: PLoS One
Title: Characterization of partial ligation-induced carotid atherosclerosis model using dual-modality molecular imaging in ApoE knock-out mice.
Volume: 8
Issue: 9
Pages: e73451
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Publication
16870825 | J:125887
First Author: Hafezi-Moghadam A
Year: 2007
Journal: Am J Physiol Cell Physiol
Title: ApoE deficiency leads to a progressive age-dependent blood-brain barrier leakage.
Volume: 292
Issue: 4
Pages: C1256-62
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Publication
30447883 | J:335068
First Author: Rasbach E
Year: 2019
Journal: Immunobiology
Title: PACAP deficiency aggravates atherosclerosis in ApoE deficient mice.
Volume: 224
Issue: 1
Pages: 124-132
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GXD Expression
GXD Expression
   
Probe: MGI:6167579
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189797
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Apoe
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6167579
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189797
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Apoe
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6167579
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189797
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Apoe
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6167579
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189797
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Apoe
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6167579
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189797
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Apoe
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6167579
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189797
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Apoe
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6167579
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189797
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Apoe
Detected: true
Specimen Num: 7
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Publication
35440098 | J:338335
First Author: Williams T
Year: 2022
Journal: Acta Neuropathol Commun
Title: Impact of APOE genotype on prion-type propagation of tauopathy.
Volume: 10
Issue: 1
Pages: 57
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Publication
29483128 | J:261602
First Author: Ulrich JD
Year: 2018
Journal: J Exp Med
Title: ApoE facilitates the microglial response to amyloid plaque pathology.
Volume: 215
Issue: 4
Pages: 1047-1058
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Publication
22606237 | J:187245
First Author: Gaudreault N
Year: 2012
Journal: PLoS One
Title: Macrophage-specific apoE gene repair reduces diet-induced hyperlipidemia and atherosclerosis in hypomorphic Apoe mice.
Volume: 7
Issue: 5
Pages: e35816
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Publication
24933211 | J:218860
First Author: Jia C
Year: 2014
Journal: PLoS One
Title: Notoginsenoside R1 attenuates atherosclerotic lesions in ApoE deficient mouse model.
Volume: 9
Issue: 6
Pages: e99849
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Publication
36012328 | J:327941
 
First Author: Hada Y
Year: 2022
Journal: Int J Mol Sci
Title: Cilostazol Attenuates AngII-Induced Cardiac Fibrosis in apoE Deficient Mice.
Volume: 23
Issue: 16
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Publication
21715678 | J:178363
First Author: Castellano JM
Year: 2011
Journal: Sci Transl Med
Title: Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.
Volume: 3
Issue: 89
Pages: 89ra57
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Publication
29267398 | J:254621
First Author: Stöhr R
Year: 2017
Journal: PLoS One
Title: Annexin A5 reduces early plaque formation in ApoE -/- mice.
Volume: 12
Issue: 12
Pages: e0190229
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Publication
21550340 | J:172657
First Author: Zhang HL
Year: 2011
Journal: Exp Neurol
Title: APOE ε3 attenuates experimental autoimmune neuritis by modulating T cell, macrophage and Schwann cell functions.
Volume: 230
Issue: 2
Pages: 197-206
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Publication
24386260 | J:209843
First Author: Sastre C
Year: 2013
Journal: PLoS One
Title: Hyperlipidemia-associated renal damage decreases Klotho expression in kidneys from ApoE knockout mice.
Volume: 8
Issue: 12
Pages: e83713
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Publication
18621483 | J:138855
First Author: Nwosu I
Year: 2008
Journal: Neurosci Lett
Title: Impact of apoE deficiency during synaptic remodeling in the mouse olfactory bulb.
Volume: 441
Issue: 3
Pages: 282-5
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Publication
23847387 | J:219323
First Author: Kawase R
Year: 2013
Journal: Cardiovasc Res
Title: Deletion of progranulin exacerbates atherosclerosis in ApoE knockout mice.
Volume: 100
Issue: 1
Pages: 125-33
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Publication
37791598 | J:355486
First Author: Marino C
Year: 2024
Journal: Alzheimers Dement
Title: APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation.
Volume: 20
Issue: 2
Pages: 819-836
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Publication
14741101 | J:107702
First Author: DeMattos RB
Year: 2004
Journal: Neuron
Title: ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo.
Volume: 41
Issue: 2
Pages: 193-202
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Publication
10514484 | J:58019
First Author: Fagan AM
Year: 1999
Journal: J Biol Chem
Title: Unique lipoproteins secreted by primary astrocytes from wild type, apoE (-/-), and human apoE transgenic mice.
Volume: 274
Issue: 42
Pages: 30001-7
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Publication
17050040 | J:130696
First Author: Osorio C
Year: 2007
Journal: Neurobiol Aging
Title: Mortalin is regulated by APOE in hippocampus of AD patients and by human APOE in TR mice.
Volume: 28
Issue: 12
Pages: 1853-62
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Publication
23845000 | J:239196
 
First Author: Hussain A
Year: 2013
Journal: J Biomed Sci
Title: Isoform-specific effects of apoE on neurite outgrowth in olfactory epithelium culture.
Volume: 20
Pages: 49
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Publication
26512759 | J:226383
First Author: Soto I
Year: 2015
Journal: PLoS Biol
Title: APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction.
Volume: 13
Issue: 10
Pages: e1002279
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Publication
32199103 | J:298380
First Author: Zhao N
Year: 2020
Journal: Neuron
Title: Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways.
Volume: 106
Issue: 5
Pages: 727-742.e6
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Publication
15312961 | J:102326
First Author: Nilsson LN
Year: 2004
Journal: Neurobiol Aging
Title: Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation.
Volume: 25
Issue: 9
Pages: 1153-67
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Publication
31554665 | J:290873
 
First Author: Jones NS
Year: 2019
Journal: eNeuro
Title: Metabolic Disturbances of a High-Fat Diet Are Dependent on APOE Genotype and Sex.
Volume: 6
Issue: 5
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Publication
15863838 | J:100499
First Author: Gerritsen G
Year: 2005
Journal: J Lipid Res
Title: ApoC-III deficiency prevents hyperlipidemia induced by apoE overexpression.
Volume: 46
Issue: 7
Pages: 1466-73
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Publication
19422789 | J:150595
First Author: Tu JL
Year: 2009
Journal: Biochem Biophys Res Commun
Title: APOE 4 polymorphism results in early cognitive deficits in an EAE model.
Volume: 384
Issue: 4
Pages: 466-70
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Publication
16837105 | J:123898
First Author: Manelli AM
Year: 2007
Journal: Neurobiol Aging
Title: Abeta42 neurotoxicity in primary co-cultures: effect of apoE isoform and Abeta conformation.
Volume: 28
Issue: 8
Pages: 1139-47
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Publication
29216448 | J:256096
First Author: Huynh TV
Year: 2017
Journal: Neuron
Title: Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis.
Volume: 96
Issue: 5
Pages: 1013-1023.e4
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Publication
21880781 | J:178337
First Author: Yang CP
Year: 2011
Journal: Development
Title: ApoE is required for maintenance of the dentate gyrus neural progenitor pool.
Volume: 138
Issue: 20
Pages: 4351-62
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Publication
23999864 | J:203828
First Author: Fan J
Year: 2013
Journal: J Lipid Res
Title: Hormonal modulators of glial ABCA1 and apoE levels.
Volume: 54
Issue: 11
Pages: 3139-50
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GO Term
GO:0071828 | apolipoprotein E recycling
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Publication
38416841 | J:358312
First Author: Jiang S
Year: 2024
Journal: Sci Transl Med
Title: APOE from patient-derived astrocytic extracellular vesicles alleviates neuromyelitis optica spectrum disorder in a mouse model.
Volume: 16
Issue: 736
Pages: eadg5116
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Publication
11165374 | J:67204
First Author: Ramassamy C
Year: 2001
Journal: Brain Res Mol Brain Res
Title: Impact of apoE deficiency on oxidative insults and antioxidant levels in the brain.
Volume: 86
Issue: 1-2
Pages: 76-83
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Publication
36436561 | J:334360
First Author: Fernandez A
Year: 2023
Journal: J Biol Chem
Title: Lack of ApoE inhibits ADan amyloidosis in a mouse model of familial Danish dementia.
Volume: 299
Issue: 1
Pages: 102751
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Publication
33446799 | J:300386
First Author: Sanada J
Year: 2021
Journal: Sci Rep
Title: Dulaglutide exerts beneficial anti atherosclerotic effects in ApoE knockout mice with diabetes: the earlier, the better.
Volume: 11
Issue: 1
Pages: 1425
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Publication
25858322 | J:228393
First Author: Foss CA
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Molecular imaging of inflammation in the ApoE -/- mouse model of atherosclerosis with IodoDPA.
Volume: 461
Issue: 1
Pages: 70-5
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Publication
24265824 | J:209659
First Author: Hoekstra M
Year: 2013
Journal: PLoS One
Title: Leukocytosis and enhanced susceptibility to endotoxemia but not atherosclerosis in adrenalectomized APOE knockout mice.
Volume: 8
Issue: 11
Pages: e80441
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Publication
33958804 | J:320448
First Author: Zalocusky KA
Year: 2021
Journal: Nat Neurosci
Title: Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease.
Volume: 24
Issue: 6
Pages: 786-798
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Publication
12551940 | J:82573
First Author: Raffaï RL
Year: 2003
Journal: J Biol Chem
Title: Hepatocyte-derived ApoE is more effective than non-hepatocyte-derived ApoE in remnant lipoprotein clearance.
Volume: 278
Issue: 13
Pages: 11670-5
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Publication
7581381 | J:28261
First Author: van Ree JH
Year: 1995
Journal: Hum Mol Genet
Title: Inactivation of Apoe and Apoc1 by two consecutive rounds of gene targeting: effects on mRNA expression levels of gene cluster members.
Volume: 4
Issue: 8
Pages: 1403-9
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Publication
28472244 | J:258824
First Author: Hirano Y
Year: 2017
Journal: Cardiovasc Res
Title: Surfactant protein-D deficiency suppresses systemic inflammation and reduces atherosclerosis in ApoE knockout mice.
Volume: 113
Issue: 10
Pages: 1208-1218
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Publication
28013147 | J:272140
 
First Author: Dhar-Mascareno M
Year: 2017
Journal: Int J Biochem Cell Biol
Title: Hexim1 heterozygosity stabilizes atherosclerotic plaque and decreased steatosis in ApoE null mice fed atherogenic diet.
Volume: 83
Pages: 56-64
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Publication
18297066 | J:131733
First Author: Gallardo G
Year: 2008
Journal: Nat Neurosci
Title: A molecular pathway of neurodegeneration linking alpha-synuclein to ApoE and Abeta peptides.
Volume: 11
Issue: 3
Pages: 301-8
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Publication
37091976 | J:335775
 
First Author: Chang GR
Year: 2023
Journal: Front Cell Dev Biol
Title: Kefir peptides attenuate atherosclerotic vascular calcification and osteoporosis in atherogenic diet-fed ApoE (-/-) knockout mice.
Volume: 11
Pages: 1158812
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Publication
29175670 | J:327531
 
First Author: von Hardenberg S
Year: 2018
Journal: J Nutr Biochem
Title: ApoE is a major determinant of hepatic bile acid homeostasis in mice.
Volume: 52
Pages: 82-91
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Publication
39844286 | J:361570
First Author: Tran KM
Year: 2025
Journal: Mol Neurodegener
Title: APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology.
Volume: 20
Issue: 1
Pages: 9
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Publication
24943223 | J:271160
First Author: Stöhr R
Year: 2014
Journal: Atherosclerosis
Title: Loss of TIMP3 exacerbates atherosclerosis in ApoE null mice.
Volume: 235
Issue: 2
Pages: 438-43
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Publication
34757086 | J:324453
 
First Author: Weller AE
Year: 2022
Journal: Neurosci Res
Title: Analysis of differential gene expression and transcript usage in hippocampus of Apoe null mutant mice: Implications for Alzheimer's disease.
Volume: 176
Pages: 85-89
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Publication
19297024 | J:148359
First Author: An G
Year: 2009
Journal: Mol Immunol
Title: CD59 but not DAF deficiency accelerates atherosclerosis in female ApoE knockout mice.
Volume: 46
Issue: 8-9
Pages: 1702-9
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Publication
32007397 | J:293293
 
First Author: Krishnamurthy K
Year: 2020
Journal: Brain Res
Title: ApoE mimetic improves pathology and memory in a model of Alzheimer's disease.
Volume: 1733
Pages: 146685
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Publication
26632270 | J:228319
 
First Author: Arnold L
Year: 2015
Journal: Nat Commun
Title: CX3CR1 deficiency promotes muscle repair and regeneration by enhancing macrophage ApoE production.
Volume: 6
Pages: 8972
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Publication
35418601 | J:334990
First Author: Giannisis A
Year: 2022
Journal: Mol Psychiatry
Title: Brain integrity is altered by hepatic APOE ε4 in humanized-liver mice.
Volume: 27
Issue: 8
Pages: 3533-3543
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