| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
ATF3 belongs to the ATF/cAMP-response element-binding protein family. It is a transcriptional activator that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It serves as a hub in cellular adaptive-response and plays important roles in cancer and immunity [, ]. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
181
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7461650 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-04-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7466119 |
| Age: |
postnatal day 7 |
|
|
| Specimen Label: |
Atf3 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim WH |
| Year: |
2011 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
ATF3 inhibits PDX-1-stimulated transactivation. |
| Volume: |
414 |
| Issue: |
4 |
| Pages: |
681-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hai T |
| Year: |
2010 |
| Journal: |
Gene Expr |
| Title: |
ATF3, a hub of the cellular adaptive-response network, in the pathogenesis of diseases: is modulation of inflammation a unifying component? |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
1-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hai T |
| Year: |
2011 |
| Journal: |
Methods Enzymol |
| Title: |
Immunohistochemical detection of activating transcription factor 3, a hub of the cellular adaptive-response network. |
| Volume: |
490 |
|
| Pages: |
175-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Iezaki T |
| Year: |
2016 |
| Journal: |
J Pathol |
| Title: |
ATF3 deficiency in chondrocytes alleviates osteoarthritis development. |
| Volume: |
239 |
| Issue: |
4 |
| Pages: |
426-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yoshida T |
| Year: |
2008 |
| Journal: |
J Am Soc Nephrol |
| Title: |
ATF3 protects against renal ischemia-reperfusion injury. |
| Volume: |
19 |
| Issue: |
2 |
| Pages: |
217-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu Y |
| Year: |
2020 |
| Journal: |
Front Cell Dev Biol |
| Title: |
ATF3 Prevents Stress-Induced Hematopoietic Stem Cell Exhaustion. |
| Volume: |
8 |
|
| Pages: |
585771 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jang MK |
| Year: |
2015 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
ATF3 inhibits PPARγ-stimulated transactivation in adipocyte cells. |
| Volume: |
456 |
| Issue: |
1 |
| Pages: |
80-5 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
181
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
124
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
181
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Boespflug ND |
| Year: |
2014 |
| Journal: |
Blood |
| Title: |
ATF3 is a novel regulator of mouse neutrophil migration. |
| Volume: |
123 |
| Issue: |
13 |
| Pages: |
2084-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Niethamer TK |
| Year: |
2023 |
| Journal: |
Elife |
| Title: |
Atf3 defines a population of pulmonary endothelial cells essential for lung regeneration. |
| Volume: |
12 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fukasawa K |
| Year: |
2016 |
| Journal: |
Sci Rep |
| Title: |
ATF3 controls proliferation of osteoclast precursor and bone remodeling. |
| Volume: |
6 |
|
| Pages: |
30918 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gold ES |
| Year: |
2012 |
| Journal: |
J Exp Med |
| Title: |
ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation. |
| Volume: |
209 |
| Issue: |
4 |
| Pages: |
807-17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Z |
| Year: |
2018 |
| Journal: |
Oncogene |
| Title: |
Atf3 deficiency promotes genome instability and spontaneous tumorigenesis in mice. |
| Volume: |
37 |
| Issue: |
1 |
| Pages: |
18-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jang MK |
| Year: |
2014 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
ATF3 represses PPARγ expression and inhibits adipocyte differentiation. |
| Volume: |
454 |
| Issue: |
1 |
| Pages: |
58-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hoetzenecker W |
| Year: |
2011 |
| Journal: |
Nat Med |
| Title: |
ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression. |
| Volume: |
18 |
| Issue: |
1 |
| Pages: |
128-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tsai WW |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
ATF3 mediates inhibitory effects of ethanol on hepatic gluconeogenesis. |
| Volume: |
112 |
| Issue: |
9 |
| Pages: |
2699-704 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gilchrist M |
| Year: |
2010 |
| Journal: |
Blood |
| Title: |
A key role for ATF3 in regulating mast cell survival and mediator release. |
| Volume: |
115 |
| Issue: |
23 |
| Pages: |
4734-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wolford CC |
| Year: |
2013 |
| Journal: |
J Clin Invest |
| Title: |
Transcription factor ATF3 links host adaptive response to breast cancer metastasis. |
| Volume: |
123 |
| Issue: |
7 |
| Pages: |
2893-906 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee YS |
| Year: |
2013 |
| Journal: |
Diabetologia |
| Title: |
Hypothalamic ATF3 is involved in regulating glucose and energy metabolism in mice. |
| Volume: |
56 |
| Issue: |
6 |
| Pages: |
1383-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang A |
| Year: |
2008 |
| Journal: |
BMC Cancer |
| Title: |
The transcription factor ATF3 acts as an oncogene in mouse mammary tumorigenesis. |
| Volume: |
8 |
|
| Pages: |
268 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kalfon R |
| Year: |
2019 |
| Journal: |
PLoS One |
| Title: |
JDP2 and ATF3 deficiencies dampen maladaptive cardiac remodeling and preserve cardiac function. |
| Volume: |
14 |
| Issue: |
2 |
| Pages: |
e0213081 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim DE |
| Year: |
2017 |
| Journal: |
J Exp Med |
| Title: |
Convergent roles of ATF3 and CSL in chromatin control of cancer-associated fibroblast activation. |
| Volume: |
214 |
| Issue: |
8 |
| Pages: |
2349-2368 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vu TTM |
| Year: |
2020 |
| Journal: |
Biochemistry |
| Title: |
The ATF3 Transcription Factor Is a Short-Lived Substrate of the Arg/N-Degron Pathway. |
| Volume: |
59 |
| Issue: |
30 |
| Pages: |
2796-2812 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu Y |
| Year: |
2021 |
| Journal: |
Nat Metab |
| Title: |
Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism. |
| Volume: |
3 |
| Issue: |
1 |
| Pages: |
59-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Delitsikou V |
| Year: |
2020 |
| Journal: |
FASEB J |
| Title: |
Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress. |
| Volume: |
34 |
| Issue: |
2 |
| Pages: |
2087-2104 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim HB |
| Year: |
2006 |
| Journal: |
Diabetes |
| Title: |
NFATc4 and ATF3 negatively regulate adiponectin gene expression in 3T3-L1 adipocytes. |
| Volume: |
55 |
| Issue: |
5 |
| Pages: |
1342-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gey M |
| Year: |
2016 |
| Journal: |
Open Biol |
| Title: |
Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury. |
| Volume: |
6 |
| Issue: |
8 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cao Y |
| Year: |
2019 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Transcriptional factor ATF3 protects against colitis by regulating follicular helper T cells in Peyer's patches. |
| Volume: |
116 |
| Issue: |
13 |
| Pages: |
6286-6291 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim S |
| Year: |
2018 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Atf3 induction is a therapeutic target for obesity and metabolic diseases. |
| Volume: |
504 |
| Issue: |
4 |
| Pages: |
903-908 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang A |
| Year: |
2007 |
| Journal: |
Mol Carcinog |
| Title: |
Epidermal hyperplasia and oral carcinoma in mice overexpressing the transcription factor ATF3 in basal epithelial cells. |
| Volume: |
46 |
| Issue: |
6 |
| Pages: |
476-87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brooks AC |
| Year: |
2014 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
Endoplasmic reticulum stress-dependent activation of ATF3 mediates the late phase of ischemic preconditioning. |
| Volume: |
76 |
|
| Pages: |
138-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Seijffers R |
| Year: |
2007 |
| Journal: |
J Neurosci |
| Title: |
ATF3 increases the intrinsic growth state of DRG neurons to enhance peripheral nerve regeneration. |
| Volume: |
27 |
| Issue: |
30 |
| Pages: |
7911-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jang MK |
| Year: |
2013 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
ATF3 plays a role in adipocyte hypoxia-mediated mitochondria dysfunction in obesity. |
| Volume: |
431 |
| Issue: |
3 |
| Pages: |
421-7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6167889 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689419 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:6189821 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table S2 - E11.5 - Atf3 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6167889 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689421 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:6189821 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
Table S2 - E13.5 - Atf3 |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6167889 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689424 |
|
| Stage: |
TS24 |
| Assay Id: |
MGI:6189821 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
Table S2 - E15.5 - Atf3 |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6167889 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689426 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:6189821 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
Table S2 - E18.5 - Atf3 |
| Detected: |
false |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6167889 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6189821 |
| Age: |
postnatal day 4 |
|
|
| Specimen Label: |
Table S2 - P4 - Atf3 |
| Detected: |
false |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6167889 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6189821 |
| Age: |
postnatal day 14 |
|
|
| Specimen Label: |
Table S2 - P14 - Atf3 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6167889 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6189821 |
| Age: |
postnatal day 28 |
|
|
| Specimen Label: |
Table S2 - P28 - Atf3 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang S |
| Year: |
2023 |
| Journal: |
Nat Commun |
| Title: |
ATF3 induction prevents precocious activation of skeletal muscle stem cell by regulating H2B expression. |
| Volume: |
14 |
| Issue: |
1 |
| Pages: |
4978 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kalfon R |
| Year: |
2017 |
| Journal: |
Cardiovasc Res |
| Title: |
ATF3 expression in cardiomyocytes preserves homeostasis in the heart and controls peripheral glucose tolerance. |
| Volume: |
113 |
| Issue: |
2 |
| Pages: |
134-146 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu Z |
| Year: |
2022 |
| Journal: |
Cell Metab |
| Title: |
ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes. |
| Volume: |
34 |
| Issue: |
9 |
| Pages: |
1342-1358.e7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shao Y |
| Year: |
2024 |
| Journal: |
Nat Cardiovasc Res |
| Title: |
ATF3 coordinates the survival and proliferation of cardiac macrophages and protects against ischemia-reperfusion injury. |
| Volume: |
3 |
| Issue: |
1 |
| Pages: |
28-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Turchi L |
| Year: |
2009 |
| Journal: |
Cell Death Differ |
| Title: |
ATF3 and p15PAF are novel gatekeepers of genomic integrity upon UV stress. |
| Volume: |
16 |
| Issue: |
5 |
| Pages: |
728-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bueno M |
| Year: |
2018 |
| Journal: |
Aging Cell |
| Title: |
ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis. |
| Volume: |
17 |
| Issue: |
2 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang H |
| Year: |
2012 |
| Journal: |
Mol Cell Biol |
| Title: |
The stress response mediator ATF3 represses androgen signaling by binding the androgen receptor. |
| Volume: |
32 |
| Issue: |
16 |
| Pages: |
3190-202 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hwang S |
| Year: |
2023 |
| Journal: |
Int J Mol Sci |
| Title: |
KLF10 Inhibits TGF-β-Mediated Activation of Hepatic Stellate Cells via Suppression of ATF3 Expression. |
| Volume: |
24 |
| Issue: |
16 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rosenberger CM |
| Year: |
2008 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
ATF3 regulates MCMV infection in mice by modulating IFN-gamma expression in natural killer cells. |
| Volume: |
105 |
| Issue: |
7 |
| Pages: |
2544-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen-Jennings AE |
| Year: |
2002 |
| Journal: |
J Biol Chem |
| Title: |
The roles of ATF3 in liver dysfunction and the regulation of phosphoenolpyruvate carboxykinase gene expression. |
| Volume: |
277 |
| Issue: |
22 |
| Pages: |
20020-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Taketani K |
| Year: |
2012 |
| Journal: |
Oncogene |
| Title: |
Key role of ATF3 in p53-dependent DR5 induction upon DNA damage of human colon cancer cells. |
| Volume: |
31 |
| Issue: |
17 |
| Pages: |
2210-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee S |
| Year: |
2018 |
| Journal: |
Front Immunol |
| Title: |
ATF3 Stimulates IL-17A by Regulating Intracellular Ca2+/ROS-Dependent IL-1β Activation During Streptococcus pneumoniae Infection. |
| Volume: |
9 |
|
| Pages: |
1954 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jeong BC |
| Year: |
2017 |
| Journal: |
Bone |
| Title: |
ATF3 modulates calcium signaling in osteoclast differentiation and activity by associating with c-Fos and NFATc1 proteins. |
| Volume: |
95 |
|
| Pages: |
33-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Avraham S |
| Year: |
2019 |
| Journal: |
Oncogene |
| Title: |
ATF3 and JDP2 deficiency in cancer associated fibroblasts promotes tumor growth via SDF-1 transcription. |
| Volume: |
38 |
| Issue: |
20 |
| Pages: |
3812-3823 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Z |
| Year: |
2015 |
| Journal: |
Oncogene |
| Title: |
Loss of ATF3 promotes Akt activation and prostate cancer development in a Pten knockout mouse model. |
| Volume: |
34 |
| Issue: |
38 |
| Pages: |
4975-84 |
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| Publication |
| First Author: |
Seijffers R |
| Year: |
2014 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
ATF3 expression improves motor function in the ALS mouse model by promoting motor neuron survival and retaining muscle innervation. |
| Volume: |
111 |
| Issue: |
4 |
| Pages: |
1622-7 |
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| Publication |
| First Author: |
Allen-Jennings AE |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
The roles of ATF3 in glucose homeostasis. A transgenic mouse model with liver dysfunction and defects in endocrine pancreas. |
| Volume: |
276 |
| Issue: |
31 |
| Pages: |
29507-14 |
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| Publication |
| First Author: |
Lee YS |
| Year: |
2014 |
| Journal: |
Endocr J |
| Title: |
ATF3 expression is induced by low glucose in pancreatic α and β cells and regulates glucagon but not insulin gene transcription. |
| Volume: |
61 |
| Issue: |
1 |
| Pages: |
85-90 |
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•
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| Publication |
| First Author: |
Darlyuk-Saadon I |
| Year: |
2012 |
| Journal: |
Biochim Biophys Acta |
| Title: |
The bZIP repressor proteins, c-Jun dimerization protein 2 and activating transcription factor 3, recruit multiple HDAC members to the ATF3 promoter. |
| Volume: |
1819 |
| Issue: |
11-12 |
| Pages: |
1142-53 |
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•
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| Publication |
| First Author: |
Chang YS |
| Year: |
2017 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Stress-inducible gene Atf3 in the noncancer host cells contributes to chemotherapy-exacerbated breast cancer metastasis. |
| Volume: |
114 |
| Issue: |
34 |
| Pages: |
E7159-E7168 |
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| Publication |
| First Author: |
Allison MB |
| Year: |
2018 |
| Journal: |
Diabetes |
| Title: |
Defining the Transcriptional Targets of Leptin Reveals a Role for Atf3 in Leptin Action. |
| Volume: |
67 |
| Issue: |
6 |
| Pages: |
1093-1104 |
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•
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| Publication |
| First Author: |
Koren L |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
Adult cardiac expression of the activating transcription factor 3, ATF3, promotes ventricular hypertrophy. |
| Volume: |
8 |
| Issue: |
7 |
| Pages: |
e68396 |
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•
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| Publication |
| First Author: |
Denk F |
| Year: |
2015 |
| Journal: |
Acta Neuropathol Commun |
| Title: |
Tamoxifen induces cellular stress in the nervous system by inhibiting cholesterol synthesis. |
| Volume: |
3 |
|
| Pages: |
74 |
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•
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| Publication |
| First Author: |
Holland SD |
| Year: |
2019 |
| Journal: |
eNeuro |
| Title: |
An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle. |
| Volume: |
6 |
| Issue: |
2 |
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•
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| Publication |
| First Author: |
Gilchrist M |
| Year: |
2008 |
| Journal: |
J Exp Med |
| Title: |
Activating transcription factor 3 is a negative regulator of allergic pulmonary inflammation. |
| Volume: |
205 |
| Issue: |
10 |
| Pages: |
2349-57 |
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•
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| Publication |
| First Author: |
Cheng CF |
| Year: |
2019 |
| Journal: |
Commun Biol |
| Title: |
Adipocyte browning and resistance to obesity in mice is induced by expression of ATF3. |
| Volume: |
2 |
|
| Pages: |
389 |
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•
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•
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| Publication |
| First Author: |
Cheng YC |
| Year: |
2021 |
| Journal: |
Cell Rep |
| Title: |
Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons. |
| Volume: |
36 |
| Issue: |
10 |
| Pages: |
109666 |
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•
•
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•
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| Publication |
| First Author: |
Okamoto Y |
| Year: |
2001 |
| Journal: |
Am J Pathol |
| Title: |
Transgenic mice with cardiac-specific expression of activating transcription factor 3, a stress-inducible gene, have conduction abnormalities and contractile dysfunction. |
| Volume: |
159 |
| Issue: |
2 |
| Pages: |
639-50 |
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•
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| Publication |
| First Author: |
Li HF |
| Year: |
2010 |
| Journal: |
J Am Soc Nephrol |
| Title: |
ATF3-mediated epigenetic regulation protects against acute kidney injury. |
| Volume: |
21 |
| Issue: |
6 |
| Pages: |
1003-13 |
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•
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| Publication |
| First Author: |
Hartman MG |
| Year: |
2004 |
| Journal: |
Mol Cell Biol |
| Title: |
Role for activating transcription factor 3 in stress-induced beta-cell apoptosis. |
| Volume: |
24 |
| Issue: |
13 |
| Pages: |
5721-32 |
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•
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| Publication |
| First Author: |
Brooks AC |
| Year: |
2015 |
| Journal: |
Am J Physiol Heart Circ Physiol |
| Title: |
Induction of activating transcription factor 3 limits survival following infarct-induced heart failure in mice. |
| Volume: |
309 |
| Issue: |
8 |
| Pages: |
H1326-35 |
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•
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| Publication |
| First Author: |
Duprez J |
| Year: |
2011 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Role of activating transcription factor 3 in low glucose- and thapsigargin-induced apoptosis in cultured mouse islets. |
| Volume: |
415 |
| Issue: |
2 |
| Pages: |
294-9 |
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•
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| Publication |
| First Author: |
Whitmore MM |
| Year: |
2007 |
| Journal: |
J Immunol |
| Title: |
Negative regulation of TLR-signaling pathways by activating transcription factor-3. |
| Volume: |
179 |
| Issue: |
6 |
| Pages: |
3622-30 |
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•
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| Publication |
| First Author: |
Wang L |
| Year: |
2012 |
| Journal: |
Neuroscience |
| Title: |
Increased inflammation and brain injury after transient focal cerebral ischemia in activating transcription factor 3 knockout mice. |
| Volume: |
220 |
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| Pages: |
100-8 |
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| Publication |
| First Author: |
Yan L |
| Year: |
2021 |
| Journal: |
Int J Mol Sci |
| Title: |
ATF3-Induced Mammary Tumors Exhibit Molecular Features of Human Basal-Like Breast Cancer. |
| Volume: |
22 |
| Issue: |
5 |
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•
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| Publication |
| First Author: |
Wu YL |
| Year: |
2022 |
| Journal: |
Cells |
| Title: |
Salvia miltiorrhiza Extract and Individual Synthesized Component Derivatives Induce Activating-Transcription-Factor-3-Mediated Anti-Obesity Effects and Attenuate Obesity-Induced Metabolic Disorder by Suppressing C/EBPα in High-Fat-Induced Obese Mice. |
| Volume: |
11 |
| Issue: |
6 |
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•
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| Publication |
| First Author: |
Turchi L |
| Year: |
2008 |
| Journal: |
Cell Death Differ |
| Title: |
Hif-2alpha mediates UV-induced apoptosis through a novel ATF3-dependent death pathway. |
| Volume: |
15 |
| Issue: |
9 |
| Pages: |
1472-80 |
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•
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| Publication |
| First Author: |
Zhou H |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
Activating transcription factor 3 deficiency promotes cardiac hypertrophy, dysfunction, and fibrosis induced by pressure overload. |
| Volume: |
6 |
| Issue: |
10 |
| Pages: |
e26744 |
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•
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| Publication |
| First Author: |
Pai CS |
| Year: |
2018 |
| Journal: |
Front Mol Neurosci |
| Title: |
The Activating Transcription Factor 3 (Atf3) Homozygous Knockout Mice Exhibit Enhanced Conditioned Fear and Down Regulation of Hippocampal GELSOLIN. |
| Volume: |
11 |
|
| Pages: |
37 |
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| Publication |
| First Author: |
Fernández-Verdejo R |
| Year: |
2017 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Activating transcription factor 3 regulates chemokine expression in contracting C2C12 myotubes and in mouse skeletal muscle after eccentric exercise. |
| Volume: |
492 |
| Issue: |
2 |
| Pages: |
249-254 |
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•
•
•
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| Publication |
| First Author: |
Zmuda EJ |
| Year: |
2010 |
| Journal: |
Mol Endocrinol |
| Title: |
The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction. |
| Volume: |
24 |
| Issue: |
7 |
| Pages: |
1423-33 |
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•
•
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| Publication |
| First Author: |
Fernández-Verdejo R |
| Year: |
2017 |
| Journal: |
FASEB J |
| Title: |
Activating transcription factor 3 attenuates chemokine and cytokine expression in mouse skeletal muscle after exercise and facilitates molecular adaptation to endurance training. |
| Volume: |
31 |
| Issue: |
2 |
| Pages: |
840-851 |
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•
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•
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| Publication |
| First Author: |
Liu B |
| Year: |
2006 |
| Journal: |
Horm Res |
| Title: |
Activating transcription factor 3 is estrogen-responsive in utero and upregulated during sexual differentiation. |
| Volume: |
65 |
| Issue: |
5 |
| Pages: |
217-22 |
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•
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| Publication |
| First Author: |
Spassov S |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Genetic targets of hydrogen sulfide in ventilator-induced lung injury--a microarray study. |
| Volume: |
9 |
| Issue: |
7 |
| Pages: |
e102401 |
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•
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| Publication |
| First Author: |
Cao Y |
| Year: |
2020 |
| Journal: |
J Immunol |
| Title: |
Critical Role of Intestinal Microbiota in ATF3-Mediated Gut Immune Homeostasis. |
| Volume: |
205 |
| Issue: |
3 |
| Pages: |
842-852 |
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