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Search results 1 to 100 out of 1069 for Brd4

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Hits by Category

Hits by Strain

Type Details Score
Gene
23476 | BRD4
Type: gene
Organism: human
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Gene
100216259 | brd4
Type: gene
Organism: frog, western clawed
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Gene
362844 | Brd4
Type: gene
Organism: rat
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Gene
455794 | BRD4
Type: gene
Organism: chimpanzee
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Gene
484869 | BRD4
Type: gene
Organism: dog, domestic
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Gene
614048 | BRD4
Type: gene
Organism: cattle
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Gene
100859056 | BRD4
Type: gene
Organism: chicken
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Gene
570531 | brd4
Type: gene
Organism: zebrafish
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Gene
718195 | BRD4
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1888520 | Brd4
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
16109376 | J:101015
First Author: Jang MK
Year: 2005
Journal: Mol Cell
Title: The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.
Volume: 19
Issue: 4
Pages: 523-34
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Publication
34700039 | J:317597
 
First Author: Paradise CR
Year: 2022
Journal: Bone
Title: Brd4 is required for chondrocyte differentiation and endochondral ossification.
Volume: 154
Pages: 116234
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Publication
27159561 | J:331732
First Author: Devaiah BN
Year: 2016
Journal: Nat Struct Mol Biol
Title: BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin.
Volume: 23
Issue: 6
Pages: 540-8
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Publication
29379197 | J:266339
First Author: Olley G
Year: 2018
Journal: Nat Genet
Title: BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange-like syndrome.
Volume: 50
Issue: 3
Pages: 329-332
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Publication
17329240 | J:123263
First Author: Wu SY
Year: 2007
Journal: J Biol Chem
Title: The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation.
Volume: 282
Issue: 18
Pages: 13141-5
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Publication
24860166 | J:218137
First Author: Itzen F
Year: 2014
Journal: Nucleic Acids Res
Title: Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation.
Volume: 42
Issue: 12
Pages: 7577-90
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Publication
25691659 | J:224421
First Author: Bryant JM
Year: 2015
Journal: Mol Cell Biol
Title: Characterization of BRD4 during mammalian postmeiotic sperm development.
Volume: 35
Issue: 8
Pages: 1433-48
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Publication
34611363 | J:342642
First Author: Linares-Saldana R
Year: 2021
Journal: Nat Genet
Title: BRD4 orchestrates genome folding to promote neural crest differentiation.
Volume: 53
Issue: 10
Pages: 1480-1492
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Publication
32526163 | J:297174
First Author: Xiang Y
Year: 2020
Journal: Mol Cell
Title: Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons.
Volume: 79
Issue: 1
Pages: 84-98.e9
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Publication
30842097 | J:277099
 
First Author: Dey A
Year: 2019
Journal: EMBO J
Title: BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses.
Volume: 38
Issue: 7
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Publication
26301327 | J:226248
First Author: Korb E
Year: 2015
Journal: Nat Neurosci
Title: BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice.
Volume: 18
Issue: 10
Pages: 1464-73
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Publication
24954901 | J:215481
First Author: Stanlie A
Year: 2014
Journal: Mol Cell
Title: Chromatin reader Brd4 functions in Ig class switching as a repair complex adaptor of nonhomologous end-joining.
Volume: 55
Issue: 1
Pages: 97-110
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Publication
29972774 | J:271646
First Author: Gegonne A
Year: 2018
Journal: Cell Rep
Title: Immature CD8 Single-Positive Thymocytes Are a Molecularly Distinct Subpopulation, Selectively Dependent on BRD4 for Their Differentiation.
Volume: 24
Issue: 1
Pages: 117-129
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Publication
34037670 | J:339825
 
First Author: Milner JJ
Year: 2021
Journal: J Exp Med
Title: Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection.
Volume: 218
Issue: 8
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Publication
16339075 | J:111726
First Author: Nishiyama A
Year: 2006
Journal: Mol Biol Cell
Title: Brd4 is required for recovery from antimicrotubule drug-induced mitotic arrest: preservation of acetylated chromatin.
Volume: 17
Issue: 2
Pages: 814-23
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Publication
25242322 | J:218548
First Author: Bolden JE
Year: 2014
Journal: Cell Rep
Title: Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition.
Volume: 8
Issue: 6
Pages: 1919-1929
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Publication
31292434 | J:278397
First Author: Penas C
Year: 2019
Journal: Nat Commun
Title: Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis.
Volume: 10
Issue: 1
Pages: 3028
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Publication
28262505 | J:251939
First Author: Cheung KL
Year: 2017
Journal: Mol Cell
Title: Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.
Volume: 65
Issue: 6
Pages: 1068-1080.e5
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Publication
19103749 | J:145726
First Author: Huang B
Year: 2009
Journal: Mol Cell Biol
Title: Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA.
Volume: 29
Issue: 5
Pages: 1375-87
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Publication
30830987 | J:277882
First Author: Gorvin CM
Year: 2019
Journal: J Bone Miner Res
Title: Mice with a Brd4 Mutation Represent a New Model of Nephrocalcinosis.
Volume: 34
Issue: 7
Pages: 1324-1335
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Publication
33015071 | J:299026
 
First Author: Kannan-Sundhari A
Year: 2020
Journal: Front Cell Dev Biol
Title: Bromodomain Protein BRD4 Is Essential for Hair Cell Function and Survival.
Volume: 8
Pages: 576654
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Publication
28823556 | J:247700
First Author: Korb E
Year: 2017
Journal: Cell
Title: Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition.
Volume: 170
Issue: 6
Pages: 1209-1223.e20
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Publication
29263365 | J:254909
First Author: Lee JE
Year: 2017
Journal: Nat Commun
Title: Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis.
Volume: 8
Issue: 1
Pages: 2217
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Publication
22509028 | J:183914
First Author: Devaiah BN
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain.
Volume: 109
Issue: 18
Pages: 6927-32
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Publication
32392533 | J:318038
First Author: Wang H
Year: 2020
Journal: Aging (Albany NY)
Title: BRD4 contributes to LPS-induced macrophage senescence and promotes progression of atherosclerosis-associated lipid uptake.
Volume: 12
Issue: 10
Pages: 9240-9259
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Publication
25146928 | J:230215
First Author: Liu W
Year: 2014
Journal: Cell Death Differ
Title: BRD4 regulates Nanog expression in mouse embryonic stem cells and preimplantation embryos.
Volume: 21
Issue: 12
Pages: 1950-60
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Publication
33086063 | J:323572
First Author: Kong IY
Year: 2020
Journal: Cell Rep
Title: Temporal Analysis of Brd4 Displacement in the Control of B Cell Survival, Proliferation, and Differentiation.
Volume: 33
Issue: 3
Pages: 108290
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Publication
39196112 | J:357409
First Author: Padmanabhan A
Year: 2024
Journal: Nat Cardiovasc Res
Title: A genome-wide CRISPR screen identifies BRD4 as a regulator of cardiomyocyte differentiation.
Volume: 3
Issue: 3
Pages: 317-331
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Publication
37399380 | J:344743
First Author: Pérez-Cabello JA
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS.
Volume: 120
Issue: 28
Pages: e2302143120
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Publication
23759512 | J:199074
First Author: Tang X
Year: 2013
Journal: Am J Pathol
Title: Assessment of Brd4 inhibition in idiopathic pulmonary fibrosis lung fibroblasts and in vivo models of lung fibrosis.
Volume: 183
Issue: 2
Pages: 470-9
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Publication
28844955 | J:255470
First Author: Jiang Y
Year: 2017
Journal: Biochim Biophys Acta
Title: BRD4 has dual effects on the HMGB1 and NF-κB signalling pathways and is a potential therapeutic target for osteoarthritis.
Volume: 1863
Issue: 12
Pages: 3001-3015
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Publication
28461486 | J:242210
First Author: Bao Y
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα.
Volume: 114
Issue: 20
Pages: E3993-E4001
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Publication
38063851 | J:344936
 
First Author: Musa RE
Year: 2024
Journal: Development
Title: BRD4 binds to active cranial neural crest enhancers to regulate RUNX2 activity during osteoblast differentiation.
Volume: 151
Issue: 2
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Publication
34972067 | J:319877
 
First Author: Zeng S
Year: 2022
Journal: Int Immunopharmacol
Title: The suppression of Brd4 inhibits peripheral plasma cell differentiation and exhibits therapeutic potential for systemic lupus erythematosus.
Volume: 103
Pages: 108498
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Publication
18039861 | J:130392
First Author: Yang Z
Year: 2008
Journal: Mol Cell Biol
Title: Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression.
Volume: 28
Issue: 3
Pages: 967-76
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Publication
31697807 | J:284823
First Author: Jiang Y
Year: 2019
Journal: Blood
Title: AMP-activated protein kinase links acetyl-CoA homeostasis to BRD4 recruitment in acute myeloid leukemia.
Volume: 134
Issue: 24
Pages: 2183-2194
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Gene
29998 | BICRA
Type: gene
Organism: human
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Publication
28931940 | J:256540
First Author: Sakurai N
Year: 2017
Journal: Sci Rep
Title: BRD4 regulates adiponectin gene induction by recruiting the P-TEFb complex to the transcribed region of the gene.
Volume: 7
Issue: 1
Pages: 11962
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Publication
33094644 | J:307663
First Author: Padmanabhan A
Year: 2020
Journal: Circulation
Title: BRD4 (Bromodomain-Containing Protein 4) Interacts with GATA4 (GATA Binding Protein 4) to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes.
Volume: 142
Issue: 24
Pages: 2338-2355
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Publication
23589332 | J:204492
First Author: Patel MC
Year: 2013
Journal: Mol Cell Biol
Title: BRD4 coordinates recruitment of pause release factor P-TEFb and the pausing complex NELF/DSIF to regulate transcription elongation of interferon-stimulated genes.
Volume: 33
Issue: 12
Pages: 2497-507
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Publication
26216992 | J:226509
First Author: Yoshida H
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells.
Volume: 112
Issue: 32
Pages: E4448-57
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Publication
27068464 | J:235182
First Author: Bhagwat AS
Year: 2016
Journal: Cell Rep
Title: BET Bromodomain Inhibition Releases the Mediator Complex from Select cis-Regulatory Elements.
Volume: 15
Issue: 3
Pages: 519-530
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Publication
27498864 | J:238966
First Author: Williams CA
Year: 2016
Journal: Cell Rep
Title: Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity.
Volume: 16
Issue: 7
Pages: 1820-8
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Publication
31356816 | J:282170
First Author: Wang X
Year: 2019
Journal: Exp Cell Res
Title: Bromodomain-containing protein 4 contributes to renal fibrosis through the induction of epithelial-mesenchymal transition.
Volume: 383
Issue: 2
Pages: 111507
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Publication
31294688 | J:277685
   
First Author: Petkau N
Year: 2019
Journal: Elife
Title: Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters.
Volume: 8
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Publication
29694891 | J:271304
First Author: Tian B
Year: 2018
Journal: Cell Rep
Title: Selective Antagonists of the Bronchiolar Epithelial NF-κB-Bromodomain-Containing Protein 4 Pathway in Viral-Induced Airway Inflammation.
Volume: 23
Issue: 4
Pages: 1138-1151
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Publication
35276206 | J:359808
 
First Author: Cerqueira SR
Year: 2022
Journal: Exp Neurol
Title: BET protein inhibition promotes non-myeloid cell mediated neuroprotection after rodent spinal cord contusion.
Volume: 352
Pages: 114035
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Protein
Q3SYK2
Organism: Mus musculus/domesticus
Length: 557  
Fragment?: true
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Protein
Q63ZX2
Organism: Mus musculus/domesticus
Length: 582  
Fragment?: true
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Publication
11997514 | J:76662
First Author: Houzelstein D
Year: 2002
Journal: Mol Cell Biol
Title: Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4.
Volume: 22
Issue: 11
Pages: 3794-802
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Publication
31233750 | J:289850
 
First Author: Inoue T
Year: 2019
Journal: Eur J Pharmacol
Title: Epigenetic regulation of lipoprotein lipase gene via BRD4, which is potentially associated with adipocyte differentiation and insulin resistance.
Volume: 858
Pages: 172492
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Publication
26974661 | J:236647
First Author: Di Stefano B
Year: 2016
Journal: Nat Cell Biol
Title: C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4.
Volume: 18
Issue: 4
Pages: 371-81
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Publication
24973920 | J:227605
First Author: Tang Y
Year: 2014
Journal: Nat Med
Title: Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.
Volume: 20
Issue: 7
Pages: 732-40
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Publication
23752591 | J:199171
First Author: Proserpio V
Year: 2013
Journal: Genes Dev
Title: The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy.
Volume: 27
Issue: 11
Pages: 1299-312
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Publication
39010274 | J:352716
   
First Author: Li C
Year: 2024
Journal: Cell Prolif
Title: Compromised cell competition exhausts neural stem cells pool.
Pages: e13710
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Protein Coding Gene
MGP_CAROLIEiJ_G0021379 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023500 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023457 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023423 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023462 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023224 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1888520 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0023905 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0022725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023199 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023329 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023299 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023407 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023317 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0023947 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022474 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0022787 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020386 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022293 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10938129 | J:63928
First Author: Dey A
Year: 2000
Journal: Mol Cell Biol
Title: A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition.
Volume: 20
Issue: 17
Pages: 6537-49
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GXD Expression
GXD Expression
     
Probe: MGI:3815639
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816443
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3815639
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816443
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3815639
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816443
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3815639
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816443
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3815639
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816443
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3815639
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816443
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3815639
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816443
Age: embryonic day 4.5
Specimen Label: E4.5 blastocyst
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3815639
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816443
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:7345827
Assay Type: Western blot
Annotation Date: 2022-10-12
Strength: Present
Sex: Female
Emaps: EMAPS:1640522
Stage: TS22
Assay Id: MGI:7345830
Age: embryonic day 14.5
Specimen Label: Females CON
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7345827
Assay Type: Western blot
Annotation Date: 2022-10-12
Strength: Present
Sex: Female
Emaps: EMAPS:1640522
Stage: TS22
Assay Id: MGI:7345830
Age: embryonic day 14.5
Specimen Label: Females CON
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7345827
Assay Type: Western blot
Annotation Date: 2022-10-12
Strength: Present
Sex: Female
Emaps: EMAPS:1640522
Stage: TS22
Assay Id: MGI:7345830
Age: embryonic day 14.5
Specimen Label: Females CON
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7345827
Assay Type: Western blot
Annotation Date: 2022-10-12
Strength: Present
Sex: Female
Emaps: EMAPS:1640522
Stage: TS22
Assay Id: MGI:7345830
Age: embryonic day 14.5
Specimen Label: Females CON
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7345827
Assay Type: Western blot
Annotation Date: 2022-10-12
Strength: Present
Sex: Female
Emaps: EMAPS:1640522
Stage: TS22
Assay Id: MGI:7345830
Age: embryonic day 14.5
Specimen Label: Females cKO
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7345827
Assay Type: Western blot
Annotation Date: 2022-10-12
Strength: Present
Sex: Female
Emaps: EMAPS:1640522
Stage: TS22
Assay Id: MGI:7345830
Age: embryonic day 14.5
Specimen Label: Females cKO
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7345827
Assay Type: Western blot
Annotation Date: 2022-10-12
Strength: Present
Sex: Female
Emaps: EMAPS:1640522
Stage: TS22
Assay Id: MGI:7345830
Age: embryonic day 14.5
Specimen Label: Females cKO
Detected: true
Specimen Num: 7
•
•
•
•
•




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