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Search results 1 to 100 out of 20578 for Ca3

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Hits by Strain

Type Details Score
Gene
761 | CA3
Type: gene
Organism: human
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Gene
100496328 | ca3
Type: gene
Organism: frog, western clawed
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Gene
487032 | CA3
Type: gene
Organism: dog, domestic
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Gene
748909 | CA3
Type: gene
Organism: chimpanzee
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Gene
513212 | CA3
Type: gene
Organism: cattle
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Gene
420209 | CA3
Type: gene
Organism: chicken
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Gene
703801 | CA3
Type: gene
Organism: macaque, rhesus
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Gene
100996348 | CA3-AS1
Type: gene
Organism: human
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GXD Expression
GXD Expression
 
Probe: MGI:1314977
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6402245
Age: postnatal month 1
Image: S1J WT CA3 1 month
Specimen Label: S1J WT CA3 1 month
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:1314977
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6402245
Age: postnatal month 1
Image: S1J KO CA3 1 month
Note: Expression was unchanged in the mutant.
Specimen Label: S1J KO CA3 1 month
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:1314977
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6402245
Age: postnatal month 4
Image: S1J WT CA3 4 month
Specimen Label: S1J WT CA3 4 month
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
Probe: MGI:1314977
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6402245
Age: postnatal month 4
Image: S1J KO CA3 4 month
Note: Expression was unchanged in the mutant.
Specimen Label: S1J KO CA3 4 month
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:1929615
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6402243
Age: postnatal month 1
Image: S1J WT CA3 1 month
Specimen Label: S1J WT CA3 1 month
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:1929615
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6402243
Age: postnatal month 1
Image: S1J KO CA3 1 month
Note: Expression was unchanged in the mutant.
Specimen Label: S1J KO CA3 1 month
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:1929615
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6402243
Age: postnatal month 4
Image: S1J WT CA3 4 month
Specimen Label: S1J WT CA3 4 month
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
Probe: MGI:1929615
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6402243
Age: postnatal month 4
Image: S1J KO CA3 4 month
Note: Expression was unchanged in the mutant.
Specimen Label: S1J KO CA3 4 month
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
Probe: MGI:6860434
Assay Type: Immunohistochemistry
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6860437
Age: postnatal week 8
Image: 2B CA3 (left)
Note: Similar pattern of expression as seen in upper cortex.
Specimen Label: 2B CA3 (left)
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6860434
Assay Type: Immunohistochemistry
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6860437
Age: postnatal week 8
Image: 2B CA3 (right)
Note: Expression mainly in cytoplasm and less in nucleus.
Specimen Label: 2B CA3 (right)
Detected: true
Specimen Num: 6
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MP Term
MP:0008268 | absent hippocampus CA3 region
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HT Sample
GSM1867260
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal
Stage: 28
Structure . Name: hippocampus CA3
Notes: Dorsal CA3 pyramidal cells
Curation Status: Curated
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HT Sample
GSM1867261
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal
Stage: 28
Structure . Name: hippocampus CA3
Notes: Dorsal CA3 pyramidal cells
Curation Status: Curated
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HT Sample
GSM1867262
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal
Stage: 28
Structure . Name: hippocampus CA3
Notes: Dorsal CA3 pyramidal cells
Curation Status: Curated
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HT Sample
GSM1867263
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal
Stage: 28
Structure . Name: hippocampus CA3
Notes: Ventral CA3 pyramidal cells
Curation Status: Curated
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HT Sample
GSM1867264
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal
Stage: 28
Structure . Name: hippocampus CA3
Notes: Ventral CA3 pyramidal cells
Curation Status: Curated
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HT Sample
GSM1867265
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal
Stage: 28
Structure . Name: hippocampus CA3
Notes: Ventral CA3 pyramidal cells
Curation Status: Curated
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GXD Expression
GXD Expression
   
Probe: MGI:7280957
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-26
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7280958
Age: postnatal day 6
Specimen Label: 2 P6 CA3
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:7280957
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-26
Strength: Weak
Sex: Female
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7280958
Age: postnatal month 1.5
Note: Expression is strongest in the pyramidal cells in the CA3a,b,c subareas.
Specimen Label: 2 1.5M F CA3
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:7280957
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-26
Strength: Present
Sex: Male
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7280958
Age: postnatal month 1.5
Note: Expression is strongest in the pyramidal cells in the CA3a,b,c subareas.
Specimen Label: 2 1.5M M CA3
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:5305288
Assay Type: RNA in situ
Annotation Date: 2012-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5305941
Age: postnatal month 2
Image: 8H
Note: Expression in CA3 pyramidal neurons.
Specimen Label: 8H
Detected: true
Specimen Num: 26
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GO Term
GO:0097442 | CA3 pyramidal cell dendrite
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MP Term
MP:0008267 | abnormal hippocampus CA3 region morphology
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GXD Expression
GXD Expression
Probe: MGI:3839398
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-02-18
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4429426
Age: postnatal day 55
Image: 4b bottom
Note: Labeling is high in CA3 pyramidal neurons.
Specimen Label: 4b bottom
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-03-02
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4430412
Age: postnatal day 10
Note: Expression decreased in the CA3 region.
Specimen Label: 1E
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6504887
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6504893
Age: postnatal adult
Note: Higher intensity of expression in CA3 region.
Specimen Label: 2c
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:2386890
Assay Type: RNA in situ
Annotation Date: 2007-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277026
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3700764
Age: embryonic day 18.5
Image: 2C
Note: Expression was detected in pyramidal neurons of the CA3 region.
Specimen Label: 2C
Detected: true
Specimen Num: 1
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Publication
18618322 | -
First Author: Nishimori I
Year: 2009
Journal: J Enzyme Inhib Med Chem
Title: Carbonic anhydrase inhibitors. Cloning, characterization and inhibition studies of the cytosolic isozyme III with anions.
Volume: 24
Issue: 1
Pages: 70-6
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Protein Domain
IPR018441 | Carbonic_anhydrase_CA3
Type: Family
Description: Carbonic anhydrases (CA: ) are zinc metalloenzymes which catalyse the reversible hydration of carbon dioxide to bicarbonate [, ]. CAs have essential roles in facilitating the transport of carbon dioxide and protons in the intracellular space, across biological membranes and in the layers of the extracellular space; they are also involved in many other processes, from respiration and photosynthesis in eukaryotes to cyanate degradation in prokaryotes. There are five known evolutionarily distinct CA families (alpha, beta, gamma, delta and epsilon) that have no significant sequence identity and have structurally distinct overall folds. Some CAs are membrane-bound, while others act in the cytosol; there are several related proteins that lack enzymatic activity. The active site of alpha-CAs is well described, consisting of a zinc ion coordinated through 3 histidine residues and a water molecule/hydroxide ion that acts as a potent nucleophile. The enzyme employs a two-step mechanism: in the first step, there is a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide; in the second step, the active site is regenerated by the ionisation of the zinc-bound water molecule and the removal of a proton from the active site []. Beta- and gamma-CAs also employ a zinc hydroxide mechanism, although at least some beta-class enzymes do not have water directly coordinated to the metal ion. The alpha-CAs are found predominantly in animals but also in bacteria and green algae. There are at least 15 isoforms found in mammals, which can be subdivided into cytosolic CAs (CA-I, CA-II, CA-III, CA-VII and CA XIII), mitochondrial CAs (CA-VA and CA-VB), secreted CAs (CA-VI), membrane-associated (CA-IV, CA-IX, CA-XII and CA-XIV) and those without CA activity, the CA-related proteins (CA-RP VIII, X and XI).The beta-CAs are highly abundant in plants, diatoms, eubacteria and archaea [, ]. The beta-CAs are far more diverse in sequence than other classes, and can be divided into different clades based on sequence identity, with the plant enzymes forming two clades representing dicotyledonous and monocotyledonous plants. Characterisation of these enzymes reveals sharp differences between the beta class, which forms dimers, tetramers, hexamers and octomers, and the alpha and gamma classes, which form strictly monomers and trimers. The gamma-CAs may be the most ancient form of carbonic anhydrases, having evolved long before the alpha class, to which it is more closely related than to the beta-class [, ]. The reaction mechanism of the gamma-class is similar to that of the alpha-class, even though the overall folds are dissimilar and the active site residues differ. The delta-CAs are found in marine algae and dinoflagellates []. The epsilon-CAs are found in prokaryotes such as Thiobacillus neapolitanus (Halothiobacillus neapolitanus) in which it is a component of the carboxysome shell, where it could supply the active sites of RuBisCO in the carboxysome with the high concentrations of carbon dioxide necessary for optimal RuBisCO activity and efficient carbon fixation [].This entry represents cytosolic carbonic anhydrase CA3 [].
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Publication
21108993 | J:170253
 
First Author: Christian KM
Year: 2011
Journal: Neuroscience
Title: Chronic stress-induced hippocampal dendritic retraction requires CA3 NMDA receptors.
Volume: 174
Pages: 26-36
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GXD Expression
GXD Expression
 
Probe: MGI:3047065
Assay Type: Immunohistochemistry
Annotation Date: 2004-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3047088
Age: postnatal day 60
Note: Expression is stronger in the CA3 region than in CA1.
Specimen Label: 3G
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:3585160
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3586103
Age: postnatal day 6
Note: Expression was detected in a subset of the CA3 region.
Specimen Label: CNS
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:6113822
Assay Type: RNA in situ
Annotation Date: 2018-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6113825
Age: postnatal day 6
Image: 1N
Note: Expression in entire dentate gyrus and CA3 field of hippocampus.
Specimen Label: 1N
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:6149194
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6149195
Age: postnatal month 3
Image: 2F right
Note: Expressed in Map2-expressing pyramidal neurons from the CA3 region.
Specimen Label: 2F right
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6719226
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719235
Age: postnatal day 10
Note: High level of expression in hippocampus, especially CA3 region.
Specimen Label: S5a
Detected: true
Specimen Num: 7
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HT Sample
GSM414537 1
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal week 7-8
Stage: 28
Structure . Name: hippocampus region
Notes: CA2 / CA3 (hippocampus)
Curation Status: Curated
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HT Sample
GSM414538 1
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal week 7-8
Stage: 28
Structure . Name: hippocampus region
Notes: CA2 / CA3 (hippocampus)
Curation Status: Curated
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GXD Expression
GXD Expression
 
Probe: MGI:6719226
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:3644828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6719235
Age: postnatal adult
Note: Expression in CA1 to CA3 pyramidal region
Specimen Label: 2j
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7528960
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3644828
Stage: TS28
Assay Id: MGI:7528980
Age: postnatal adult
Note: Expression lost in CA3 pyramidal cells.
Specimen Label: 5A NeuN ko
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7280957
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284525
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7280958
Age: embryonic day 17.5
Specimen Label: 2 E17.5 CA3
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6316060
Assay Type: Immunohistochemistry
Annotation Date: 2019-07-08
Strength: Absent
Sex: Male
Emaps: EMAPS:3274328
Stage: TS28
Assay Id: MGI:6316347
Age: postnatal adult
Note: No expression in blood vessel basement membrane.
Specimen Label: Ca3 day >60
Detected: false
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:6316060
Assay Type: Immunohistochemistry
Annotation Date: 2019-07-08
Strength: Present
Sex: Male
Emaps: EMAPS:3147628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6316347
Age: postnatal adult
Note: Expression in inner and outer basal lamina.
Specimen Label: Ca3 day >60
Detected: true
Specimen Num: 12
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Publication
29355673 | J:268200
 
First Author: Chiang MC
Year: 2018
Journal: Behav Brain Res
Title: A role for CA3 in social recognition memory.
Volume: 354
Pages: 22-30
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Publication
12040087 | J:77718
First Author: Nakazawa K
Year: 2002
Journal: Science
Title: Requirement for hippocampal CA3 NMDA receptors in associative memory recall.
Volume: 297
Issue: 5579
Pages: 211-8
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GXD Expression
GXD Expression
 
Probe: MGI:3574060
Assay Type: RNA in situ
Annotation Date: 2005-04-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3574075
Age: postnatal day 7
Note: There is more expression in CA1 and CA3 pyramidal cells than in CA2 and CA4
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3655218
Assay Type: RNA in situ
Annotation Date: 2006-09-20
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3655233
Age: postnatal day 15
Note: There is modest expression in the pyramidal cell layer in CA1 to CA3 fields.
Specimen Label: 2E
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:3700750
Assay Type: RNA in situ
Annotation Date: 2007-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277026
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3700763
Age: embryonic day 18.5
Image: 2B
Note: Expression was detected in the contiguous parts of the CA1 and CA3 regions.
Specimen Label: 2B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3700751
Assay Type: RNA in situ
Annotation Date: 2007-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277026
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3700765
Age: embryonic day 18.5
Image: 2D
Note: Expression was detected in the part of the CA3 region located close to the dentate gyrus.
Specimen Label: 2D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:31382
Assay Type: RNA in situ
Annotation Date: 2010-11-16
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4838637
Age: postnatal day 7
Note: High levels of expression in hippocampus beginning at approximately CA3 and continuing into the dentate gyrus.
Specimen Label: 7c
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
Probe: MGI:6442568
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6443623
Age: postnatal week 4
Image: 5G
Note: Expression is in the stratum oriens of the CA1 and CA3 subfields of the hippocampus.
Specimen Label: 5G
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6442568
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6443623
Age: postnatal week 4
Image: 5H
Note: Expression is in the stratum oriens of the CA1 and CA3 subfields of the hippocampus.
Specimen Label: 5H
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6442568
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6443623
Age: postnatal week 4
Image: 5I
Note: Expression is in the stratum oriens of the CA1 and CA3 subfields of the hippocampus.
Specimen Label: 5I
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6442568
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6443623
Age: postnatal week 4
Image: 5J
Note: Expression is in the stratum oriens of the CA1 and CA3 subfields of the hippocampus.
Specimen Label: 5J
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7448590
Assay Type: Immunohistochemistry
Annotation Date: 2023-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7448692
Age: postnatal day 21
Image: 1E NeuN CNS-del
Note: Neurons in CA1, CA3 field and dentate gyrus less densely packed from P7 to P21.
Specimen Label: 1E NeuN CNS-del
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:7543415
Assay Type: RNA in situ
Annotation Date: 2023-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7543432
Age: postnatal adult
Note: Expression is absent in dendritic fields of the CA3 region of the Ammon's horn.
Specimen Label: 3E
Detected: true
Specimen Num: 3
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Publication
12718863 | J:107692
First Author: Nakazawa K
Year: 2003
Journal: Neuron
Title: Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience.
Volume: 38
Issue: 2
Pages: 305-15
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HT Experiment
GSE193826 | Expression data of hippocampal CA3 from Adora1 knockout and wild type mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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GXD Expression
GXD Expression
Probe: MGI:5510830
Assay Type: Immunohistochemistry
Annotation Date: 2016-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3644828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5792121
Age: postnatal day 5
Image: 11A/A'/A"/A'"
Note: More highly expressed in CA3 compared to CA2.
Specimen Label: 11A/A'/A"/A'"
Detected: true
Specimen Num: 26
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Publication
34330817 | J:322961
 
First Author: Schoenfeld G
Year: 2021
Journal: eNeuro
Title: In Vivo Calcium Imaging of CA3 Pyramidal Neuron Populations in Adult Mouse Hippocampus.
Volume: 8
Issue: 4
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GXD Expression
GXD Expression
Probe: MGI:3620148
Assay Type: RNA in situ
Annotation Date: 2006-04-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3620151
Age: postnatal adult
Image: 1E,F
Note: Expression is in part of the ventral region of the CA3 pyramidal neurons, absent in dorsal CA3 neurons.
Specimen Label: 1E,F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3710968
Assay Type: RNA in situ
Annotation Date: 2007-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3710972
Age: postnatal day 7
Note: Expression levels in the pyramidal cells of the CA1, CA2, and CA3 regions are higher than elsewhere.
Specimen Label: Hippocampus
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3763619
Assay Type: Immunohistochemistry
Annotation Date: 2007-12-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3763715
Age: postnatal adult
Note: Expression is in the perikarya of the pyramidal cells within the CA2 and CA3 (shown) areas of the hippocampus.
Specimen Label: 2G
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:3783511
Assay Type: Immunohistochemistry
Annotation Date: 2008-05-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3783872
Age: postnatal
Note: Expression in the CA1 to CA3 regions, concentrated in the stratum oriens and stratum radiatum of the CA3 region.
Specimen Label: 3A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5449001
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5449036
Age: postnatal day 7
Image: 6B
Note: Expression in CA3 pyramidal neurons in a distinct perinuclear pattern, extending slightly into the proximal region of dendrites.
Specimen Label: 6B
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2014-02-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5545811
Age: postnatal adult
Image: 5D,E
Note: Staining in the CA3 region may have been due to expression in the mossy fiber projections from the dentate gyrus.
Specimen Label: 5D,E
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:6504887
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6504894
Age: postnatal adult
Note: Highest density of expression in pyramidal cells of CA3 region. Expression colocalized with Map2 indicating expression in neurons,.
Specimen Label: 3b
Detected: true
Specimen Num: 2
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Publication
19059420 | J:179502
First Author: Betourne A
Year: 2009
Journal: Neuropharmacology
Title: Involvement of hippocampal CA3 K(ATP) channels in contextual memory.
Volume: 56
Issue: 3
Pages: 615-25
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Publication
19555647 | J:157339
First Author: Nakashiba T
Year: 2009
Journal: Neuron
Title: Hippocampal CA3 output is crucial for ripple-associated reactivation and consolidation of memory.
Volume: 62
Issue: 6
Pages: 781-7
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GXD Expression
GXD Expression
Probe: MGI:2386890
Assay Type: RNA in situ
Annotation Date: 2007-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277026
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3700764
Age: embryonic day 18.5
Image: 2G
Note: Expression was detected in pyramidal neurons of the CA3 region as in wild type, but the marked territory was smaller in the mutant.
Specimen Label: 2G
Detected: true
Specimen Num: 2
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Publication
37117012 | J:358966
First Author: Li M
Year: 2023
Journal: J Neurosci
Title: Hypothalamic Supramammillary Nucleus Selectively Excites Hippocampal CA3 Interneurons to Suppress CA3 Pyramidal Neuron Activity.
Volume: 43
Issue: 25
Pages: 4612-4624
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Publication
11340172 | J:69504
First Author: Yamada M
Year: 2001
Journal: Mol Cell Biol
Title: Loss of hippocampal CA3 pyramidal neurons in mice lacking STAM1.
Volume: 21
Issue: 11
Pages: 3807-19
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Publication
19142228 | J:144994
First Author: Fukushima F
Year: 2009
Journal: PLoS One
Title: Ablation of NMDA receptors enhances the excitability of hippocampal CA3 neurons.
Volume: 4
Issue: 1
Pages: e3993
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Publication
27022627 | J:240234
 
First Author: Yu LM
Year: 2016
Journal: eNeuro
Title: CA3 Synaptic Silencing Attenuates Kainic Acid-Induced Seizures and Hippocampal Network Oscillations.
Volume: 3
Issue: 1
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Publication
38489262 | J:347927
First Author: Nikbakht N
Year: 2024
Journal: Cell Rep
Title: Efficient encoding of aversive location by CA3 long-range projections.
Volume: 43
Issue: 3
Pages: 113957
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GXD Expression
GXD Expression
Probe: MGI:3700750
Assay Type: RNA in situ
Annotation Date: 2007-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277026
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3700763
Age: embryonic day 18.5
Image: 2F
Note: Expression was detected in the contiguous parts of the CA1 and CA3 regions as in wild type, but the marked territory is smaller in the mutant.
Specimen Label: 2F
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3700751
Assay Type: RNA in situ
Annotation Date: 2007-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277026
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3700765
Age: embryonic day 18.5
Image: 2H
Note: Expression was detected in the part of the CA3 region located close to the dentate gyrus as in control, but the marked territory was smaller in the mutant.
Specimen Label: 2H
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
Probe: MGI:5449001
Assay Type: Immunohistochemistry
Annotation Date: 2013-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5449036
Age: postnatal week 14
Image: 6C
Note: Expression in CA3 pyramidal neurons in a distinct perinuclear pattern. Authors state that much of the expression in dendritic extensions is lost.
Specimen Label: 6C
Detected: true
Specimen Num: 20
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Publication
17004940 | J:112944
First Author: Cravens CJ
Year: 2006
Journal: Eur J Neurosci
Title: CA3 NMDA receptors are crucial for rapid and automatic representation of context memory.
Volume: 24
Issue: 6
Pages: 1771-80
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•
Publication
39025678 | J:355610
 
First Author: Li M
Year: 2024
Journal: J Neurosci
Title: Dorsoventral Heterogeneity of Synaptic Connectivity in Hippocampal CA3 Pyramidal Neurons.
Volume: 44
Issue: 33
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Publication
18218862 | J:131852
First Author: Nakashiba T
Year: 2008
Journal: Science
Title: Transgenic inhibition of synaptic transmission reveals role of CA3 output in hippocampal learning.
Volume: 319
Issue: 5867
Pages: 1260-4
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GXD Expression
GXD Expression
 
Probe: MGI:6504887
Assay Type: Immunohistochemistry
Annotation Date: 2021-02-04
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3644828
Pattern: Clusters
Stage: TS28
Assay Id: MGI:6504893
Age: postnatal adult
Note: Highest density of expression in pyramidal cells of CA3 region. Uneven clustered pattern of intracelluar distribution.
Specimen Label: 2d
Detected: true
Specimen Num: 6
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Publication
21084618 | J:166441
First Author: Torborg CL
Year: 2010
Journal: J Neurosci
Title: Control of CA3 output by feedforward inhibition despite developmental changes in the excitation-inhibition balance.
Volume: 30
Issue: 46
Pages: 15628-37
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GO Term
GO:0098686 | hippocampal mossy fiber to CA3 synapse
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GXD Expression
GXD Expression
Probe: MGI:7716808
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3644828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7716871
Age: postnatal day 21
Image: 3I,L
Note: Gradually stronger expression in stratum oriens, stratum pyramidale and stratum radiatum of CA2 and CA3 compared to CA1.
Specimen Label: 3I,L
Detected: true
Specimen Num: 6
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Publication
22194569 | J:179046
First Author: Ramamoorthi K
Year: 2011
Journal: Science
Title: Npas4 regulates a transcriptional program in CA3 required for contextual memory formation.
Volume: 334
Issue: 6063
Pages: 1669-75
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Publication
30609178 | J:353130
First Author: Lee J
Year: 2019
Journal: Hippocampus
Title: Transient effect of mossy fiber stimulation on spatial firing of CA3 neurons.
Volume: 29
Issue: 7
Pages: 639-651
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Publication
33057002 | J:301447
First Author: Apóstolo N
Year: 2020
Journal: Nat Commun
Title: Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer.
Volume: 11
Issue: 1
Pages: 5171
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Publication
29279390 | J:257282
First Author: Wagatsuma A
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Locus coeruleus input to hippocampal CA3 drives single-trial learning of a novel context.
Volume: 115
Issue: 2
Pages: E310-E316
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Publication
34964210 | J:339448
First Author: Eom K
Year: 2022
Journal: Hippocampus
Title: Gradual decorrelation of CA3 ensembles associated with contextual discrimination learning is impaired by Kv1.2 insufficiency.
Volume: 32
Issue: 3
Pages: 193-216
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Publication
10727704 | J:150699
First Author: Ito I
Year: 2000
Journal: Neuropharmacology
Title: Input-specific targeting of NMDA receptor subtypes at mouse hippocampal CA3 pyramidal neuron synapses.
Volume: 39
Issue: 6
Pages: 943-51
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Publication
28912554 | J:252657
First Author: Lin YT
Year: 2017
Journal: Nat Commun
Title: Oxytocin stimulates hippocampal neurogenesis via oxytocin receptor expressed in CA3 pyramidal neurons.
Volume: 8
Issue: 1
Pages: 537
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Publication
24073232 | J:207528
First Author: Germain J
Year: 2013
Journal: PLoS One
Title: Doublecortin knockout mice show normal hippocampal-dependent memory despite CA3 lamination defects.
Volume: 8
Issue: 9
Pages: e74992
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