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Search results 1 to 100 out of 14019 for Cd4

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Hits by Strain

Type Details Score
Gene
key_979872 | Cd4
Type: gene
Organism: Not Specified
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Gene
920 | CD4
Type: gene
Organism: human
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Gene
100491070 | cd4
Type: gene
Organism: frog, western clawed
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Gene
24932 | Cd4
Type: gene
Organism: rat
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Gene
403931 | CD4
Type: gene
Organism: dog, domestic
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Gene
450124 | CD4
Type: gene
Organism: chimpanzee
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Gene
407098 | CD4
Type: gene
Organism: cattle
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Gene
395362 | CD4
Type: gene
Organism: chicken
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Gene
713807 | CD4
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR000973 | CD4
Type: Family
Description: CD4 is a glycoprotein found on the surface of T cells. It is a co-receptor that assists the T cell receptor (TCR) in communicating with an antigen-presenting cell (APC). The structure of a soluble fragment of CD4 has been determined to 2.3 A and reveals that the molecule has two intimately-associated immunoglobulin-like domains connected by a continuous beta strand. Residues implicated in HIV recognition reside in domain D1. Domain D2 is distinguished by a variation in the β-strand topologies of antibody domains that results in a truncated β-barrel with a non-standard intra-sheet disulphide bond [, ]. The binding sites for monoclonal antibodies, class II major histocompatibility complex molecules, and HIV gp120 can be mapped on the molecular surface. Ligation of CD4 by MHC-II on blood monocytes mediates macrophage differentiation and it also increases the susceptibility of blood-derived monocytes to HIV binding and subsequent infection [].
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Protein Coding Gene
MGI:88335 | Cd4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P70443
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: true
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Publication
1701030 | -
First Author: Wang JH
Year: 1990
Journal: Nature
Title: Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains.
Volume: 348
Issue: 6300
Pages: 411-8
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Publication
24942581 | -
First Author: Zhen A
Year: 2014
Journal: J Virol
Title: CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection.
Volume: 88
Issue: 17
Pages: 9934-46
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Protein
Q61396
Organism: Mus musculus/domesticus
Length: 457  
Fragment?: false
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Protein
O55054
Organism: Mus musculus/domesticus
Length: 433  
Fragment?: true
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Protein
Q3TSV7
Organism: Mus musculus/domesticus
Length: 457  
Fragment?: false
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Protein
P06332
Organism: Mus musculus/domesticus
Length: 457  
Fragment?: false
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Publication
2247146 | -
First Author: Ryu SE
Year: 1990
Journal: Nature
Title: Crystal structure of an HIV-binding recombinant fragment of human CD4.
Volume: 348
Issue: 6300
Pages: 419-26
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Publication
15457337 | J:93064
First Author: Capparelli R
Year: 2004
Journal: Mamm Genome
Title: Monoallelic expression of mouse Cd4 gene.
Volume: 15
Issue: 8
Pages: 579-84
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Publication
9521047 | J:46692
First Author: Nagase H
Year: 1998
Journal: Eur J Immunol
Title: Novel mutant mice secreting soluble CD4 without expression of membrane-bound CD4.
Volume: 28
Issue: 2
Pages: 403-12
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Publication
14978084 | J:88234
First Author: Khanolkar A
Year: 2004
Journal: J Immunol
Title: CD4 T cell-dependent CD8 T cell maturation.
Volume: 172
Issue: 5
Pages: 2834-44
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Publication
8344730 | J:16098
First Author: Wade N
Year: 1993
Journal: Immunogenetics
Title: DNA sequence analysis and polymorphism of the mouse CD4 gene.
Volume: 38
Issue: 5
Pages: 384
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Publication
2784195 | J:225416
First Author: Veillette A
Year: 1989
Journal: Nature
Title: Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck.
Volume: 338
Issue: 6212
Pages: 257-9
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Publication
16709847 | J:131790
First Author: Maekawa A
Year: 2006
Journal: J Immunol
Title: Evidence for a domain-swapped CD4 dimer as the coreceptor for binding to class II MHC.
Volume: 176
Issue: 11
Pages: 6873-8
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Publication
3027575 | J:8578
First Author: Littman DR
Year: 1987
Journal: Nature
Title: Unusual intron in the immunoglobulin domain of the newly isolated murine CD4 (L3T4) gene.
Volume: 325
Issue: 6103
Pages: 453-5
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Publication
7904347 | J:20507
First Author: Rahemtulla A
Year: 1993
Journal: Philos Trans R Soc Lond B Biol Sci
Title: CD4 negative mice as a model for immunodeficiency.
Volume: 342
Issue: 1299
Pages: 57-8
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Publication
1832488 | J:68957
First Author: Rahemtulla A
Year: 1991
Journal: Nature
Title: Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4.
Volume: 353
Issue: 6340
Pages: 180-4
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Publication
1402689 | J:110753
First Author: Wallace VA
Year: 1992
Journal: J Exp Med
Title: CD4 expression is differentially required for deletion of MLS-1a-reactive T cells.
Volume: 176
Issue: 5
Pages: 1459-63
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Publication
8145040 | J:77270
First Author: Law YM
Year: 1994
Journal: J Exp Med
Title: Human CD4 restores normal T cell development and function in mice deficient in murine CD4.
Volume: 179
Issue: 4
Pages: 1233-42
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Publication
10929052 | J:63431
First Author: Wang CR
Year: 2000
Journal: Immunology
Title: Impaired delayed-type hypersensitivity response in mutant mice secreting soluble CD4 without expression of membrane-bound CD4.
Volume: 100
Issue: 3
Pages: 309-16
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Publication
8618064 | J:32787
First Author: Kondo S
Year: 1996
Journal: J Invest Dermatol
Title: Hyporesponsiveness in contact hypersensitivity and irritant contact dermatitis in CD4 gene targeted mouse.
Volume: 106
Issue: 5
Pages: 993-1000
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Publication
32404525 | J:290222
 
First Author: Chakravarty D
Year: 2020
Journal: J Virol
Title: CD4 Deficiency Causes Poliomyelitis and Axonal Blebbing in Murine Coronavirus-Induced Neuroinflammation.
Volume: 94
Issue: 14
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Publication
3501122 | J:8995
First Author: Maddon PJ
Year: 1987
Journal: Proc Natl Acad Sci U S A
Title: Structure and expression of the human and mouse T4 genes.
Volume: 84
Issue: 24
Pages: 9155-9
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Publication
17334223 | J:134164
First Author: Kim DK
Year: 2007
Journal: Exp Mol Med
Title: A human mutant CD4 molecule resistant to HIV-1 binding restores helper T-lymphocyte functions in murine CD4-deficient mice.
Volume: 39
Issue: 1
Pages: 1-7
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Publication
34220551 | J:309587
 
First Author: Gokina NI
Year: 2021
Journal: Front Physiol
Title: Deficiency in CD4 T Cells Leads to Enhanced Postpartum Internal Carotid Artery Vasoconstriction in Mice: The Role of Nitric Oxide.
Volume: 12
Pages: 686429
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Publication
12381351 | J:115550
First Author: Saunders BM
Year: 2002
Journal: Cell Immunol
Title: CD4 is required for the development of a protective granulomatous response to pulmonary tuberculosis.
Volume: 216
Issue: 1-2
Pages: 65-72
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Publication
12218108 | J:78960
First Author: Laub R
Year: 2002
Journal: J Immunol
Title: Anti-human CD4 induces peripheral tolerance in a human CD4+, murine CD4-, HLA-DR+ advanced transgenic mouse model.
Volume: 169
Issue: 6
Pages: 2947-55
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Publication
12008044 | J:113525
First Author: Marschner S
Year: 2002
Journal: Immunol Lett
Title: Ligation of human CD4 interferes with antigen-induced activation of primary T cells.
Volume: 82
Issue: 1-2
Pages: 131-9
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Publication
8467804 | J:50435
First Author: Killeen N
Year: 1993
Journal: EMBO J
Title: Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4.
Volume: 12
Issue: 4
Pages: 1547-53
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Publication
8612128 | J:88852
First Author: Matechak EO
Year: 1996
Journal: Immunity
Title: MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.
Volume: 4
Issue: 4
Pages: 337-47
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Publication
3262426 | J:225417
First Author: Veillette A
Year: 1988
Journal: Cell
Title: The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck.
Volume: 55
Issue: 2
Pages: 301-8
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Publication
11591754 | J:118765
First Author: Wang Q
Year: 2001
Journal: J Immunol
Title: CD4 promotes breadth in the TCR repertoire.
Volume: 167
Issue: 8
Pages: 4311-20
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Publication
21071017 | J:167010
First Author: Tinsley KW
Year: 2011
Journal: Cell Immunol
Title: CD4 co-receptor dependent signaling promotes competency for re-stimulation induced cell death of effector T cells.
Volume: 266
Issue: 2
Pages: 200-7
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Publication
16818762 | J:134945
First Author: Northrop JK
Year: 2006
Journal: J Immunol
Title: Epigenetic remodeling of the IL-2 and IFN-gamma loci in memory CD8 T cells is influenced by CD4 T cells.
Volume: 177
Issue: 2
Pages: 1062-9
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Publication
18056368 | J:155035
First Author: Novy P
Year: 2007
Journal: J Immunol
Title: CD4 T cells are required for CD8 T cell survival during both primary and memory recall responses.
Volume: 179
Issue: 12
Pages: 8243-51
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Publication
1640169 | J:1594
First Author: Moore SC
Year: 1992
Journal: J Leukoc Biol
Title: Mouse macrophages contain a truncated CD4 transcript.
Volume: 52
Issue: 1
Pages: 128-9
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Publication
35385550 | J:325578
First Author: Janakiraman M
Year: 2022
Journal: PLoS One
Title: A novel CD4 knockout mouse strain with a spontaneous frameshift mutation in the CD4 locus.
Volume: 17
Issue: 4
Pages: e0266589
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Publication
9686579 | J:118762
First Author: Leitenberg D
Year: 1998
Journal: J Immunol
Title: CD4 regulation of TCR signaling and T cell differentiation following stimulation with peptides of different affinities for the TCR.
Volume: 161
Issue: 3
Pages: 1194-203
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Publication
11454058 | J:110421
First Author: Ehinger M
Year: 2001
Journal: Immunology
Title: Influence of CD4 or CD8 deficiency on collagen-induced arthritis.
Volume: 103
Issue: 3
Pages: 291-300
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Publication
11748274 | J:73479
First Author: Wang Q
Year: 2001
Journal: J Exp Med
Title: Homeostatic competition among T cells revealed by conditional inactivation of the mouse Cd4 gene.
Volume: 194
Issue: 12
Pages: 1721-30
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Publication
18981117 | J:140942
First Author: Adoro S
Year: 2008
Journal: J Immunol
Title: Targeting CD4 coreceptor expression to postselection thymocytes reveals that CD4/CD8 lineage choice is neither error-prone nor stochastic.
Volume: 181
Issue: 10
Pages: 6975-83
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Publication
35304452 | J:333574
First Author: Teghanemt A
Year: 2022
Journal: Nat Commun
Title: CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element.
Volume: 13
Issue: 1
Pages: 1477
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Publication
10586041 | J:112133
First Author: Peña-Rossi C
Year: 1999
Journal: J Immunol
Title: Negative regulation of CD4 lineage development and responses by CD5.
Volume: 163
Issue: 12
Pages: 6494-501
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Publication
12389100 | J:80480
First Author: Koskinen R
Year: 2002
Journal: Immunogenetics
Title: The chicken CD4 gene has remained conserved in evolution.
Volume: 54
Issue: 7
Pages: 520-5
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Publication
12370367 | J:120171
First Author: Boyer O
Year: 2002
Journal: J Immunol
Title: Human CD4 expression at the late single-positive stage of thymic development supports T cell maturation and peripheral export in CD4-deficient mice.
Volume: 169
Issue: 8
Pages: 4347-53
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Publication
23293358 | J:191711
First Author: Wan M
Year: 2013
Journal: J Immunol
Title: A general approach for controlling transcription and probing epigenetic mechanisms: application to the CD4 locus.
Volume: 190
Issue: 2
Pages: 737-47
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Publication
1391941 | J:2689
First Author: Wineman JP
Year: 1992
Journal: Blood
Title: CD4 is expressed on murine pluripotent hematopoietic stem cells.
Volume: 80
Issue: 7
Pages: 1717-24
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Publication
16622011 | J:131615
First Author: Moldovan MC
Year: 2006
Journal: J Immunol
Title: Triggering of T cell activation via CD4 dimers.
Volume: 176
Issue: 9
Pages: 5438-45
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Publication
12453416 | J:80576
First Author: Taniuchi I
Year: 2002
Journal: Mol Cell
Title: Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation.
Volume: 10
Issue: 5
Pages: 1083-96
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Publication
1503636 | J:575
 
First Author: Mak TW
Year: 1992
Journal: J Autoimmun
Title: Generation of mutant mice lacking surface expression of CD4 or CD8 by gene targeting.
Volume: 5 Suppl A
Pages: 55-9
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Publication
19747858 | J:152836
First Author: Sarafova SD
Year: 2009
Journal: Immunity
Title: Upregulation of CD4 expression during MHC class II-specific positive selection is essential for error-free lineage choice.
Volume: 31
Issue: 3
Pages: 480-90
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Publication
22732593 | J:189784
First Author: Stolp J
Year: 2012
Journal: J Immunol
Title: Subcongenic analyses reveal complex interactions between distal chromosome 4 genes controlling diabetogenic B cells and CD4 T cells in nonobese diabetic mice.
Volume: 189
Issue: 3
Pages: 1406-17
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Publication
8057386 | J:18051
First Author: Morrison WJ
Year: 1994
Journal: J Neurosci Res
Title: Understanding the CD4 molecule: surface expression and function.
Volume: 38
Issue: 1
Pages: 1-5
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Publication
8500525 | J:12572
First Author: Schilham MW
Year: 1993
Journal: Eur J Immunol
Title: Alloreactive cytotoxic T cells can develop and function in mice lacking both CD4 and CD8.
Volume: 23
Issue: 6
Pages: 1299-304
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Publication
8805673 | J:35433
First Author: Chen SY
Year: 1996
Journal: J Immunol
Title: The natural history of disease expression in CD4 and CD8 gene-deleted New Zealand black (NZB) mice.
Volume: 157
Issue: 6
Pages: 2676-84
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Publication
7622189 | J:112349
First Author: Rottenberg ME
Year: 1995
Journal: Immunol Lett
Title: Outcome of infection with different strains of Trypanosoma cruzi in mice lacking CD4 and/or CD8.
Volume: 45
Issue: 1-2
Pages: 53-60
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Publication
8004678 | J:18902
First Author: Sawada S
Year: 1994
Journal: Cell
Title: A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development.
Volume: 77
Issue: 6
Pages: 917-29
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Publication
28250157 | J:252344
First Author: Brahmakshatriya V
Year: 2017
Journal: J Immunol
Title: IL-6 Production by TLR-Activated APC Broadly Enhances Aged Cognate CD4 Helper and B Cell Antibody Responses In Vivo.
Volume: 198
Issue: 7
Pages: 2819-2833
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Publication
9551897 | J:45168
First Author: Frank GD
Year: 1998
Journal: J Immunol
Title: The level of CD4 surface protein influences T cell selection in the thymus.
Volume: 160
Issue: 2
Pages: 634-42
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Publication
7676644 | J:110749
First Author: Berke Z
Year: 1995
Journal: Virology
Title: Polyomavirus persists in CD4/8 double-knockout, but not in CD4 or CD8 single-knockout mice.
Volume: 212
Issue: 1
Pages: 268-71
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Publication
1533274 | J:113701
First Author: Seong RH
Year: 1992
Journal: Nature
Title: Signal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tail.
Volume: 356
Issue: 6371
Pages: 718-20
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Publication
29028486 | J:251769
 
First Author: Wang H
Year: 2017
Journal: Mol Immunol
Title: A point mutation in the extracellular domain of CD4 completely abolishes CD4 T cell development in C57BL/6 mouse.
Volume: 92
Pages: 12-20
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Publication
8596039 | J:292874
First Author: Salmon P
Year: 1996
Journal: J Immunol
Title: Characterization of an intronless CD4 minigene expressed in mature CD4 and CD8 T cells, but not expressed in immature thymocytes.
Volume: 156
Issue: 5
Pages: 1873-9
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Publication
3094146 | J:32618
First Author: Tourvieille B
Year: 1986
Journal: Science
Title: Isolation and sequence of L3T4 complementary DNA clones: expression in T cells and brain.
Volume: 234
Issue: 4776
Pages: 610-4
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Publication
8062832 | J:19770
First Author: Siu G
Year: 1994
Journal: EMBO J
Title: A transcriptional silencer controls the developmental expression of the CD4 gene.
Volume: 13
Issue: 15
Pages: 3570-9
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Publication
8088877 | J:18579
First Author: Winkel K
Year: 1994
Journal: Immunol Lett
Title: CD4 and CD8 expression by human and mouse thymic dendritic cells.
Volume: 40
Issue: 2
Pages: 93-9
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Publication
15662027 | J:106869
First Author: Zhou X
Year: 2005
Journal: Circ Res
Title: Lesion development and response to immunization reveal a complex role for CD4 in atherosclerosis.
Volume: 96
Issue: 4
Pages: 427-34
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Publication
8225589 | J:111017
First Author: Rottenberg ME
Year: 1993
Journal: Infect Immun
Title: Differential susceptibilities of mice genomically deleted of CD4 and CD8 to infections with Trypanosoma cruzi or Trypanosoma brucei.
Volume: 61
Issue: 12
Pages: 5129-33
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Publication
10222057 | J:114269
First Author: Senaldi G
Year: 1999
Journal: Cell Immunol
Title: Corynebacterium parvum- and Mycobacterium bovis Bacillus Calmette and Guerin-induced granuloma formation in mice lacking CD4 and CD8.
Volume: 193
Issue: 2
Pages: 155-61
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Publication
33329524 | J:312591
 
First Author: Taylor MD
Year: 2020
Journal: Front Immunol
Title: CD4 and CD8 T Cell Memory Interactions Alter Innate Immunity and Organ Injury in the CLP Sepsis Model.
Volume: 11
Pages: 563402
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Publication
10929051 | J:63432
First Author: Wormley FL Jr
Year: 2000
Journal: Immunology
Title: Evidence for a unique expression of CD4 on murine vaginal CD4+ cells.
Volume: 100
Issue: 3
Pages: 300-8
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Publication
7613876 | J:25478
First Author: Guo MW
Year: 1995
Journal: Zygote
Title: Molecular structure and function of CD4 on murine egg plasma membrane.
Volume: 3
Issue: 1
Pages: 65-73
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Publication
8996248 | J:37572
First Author: Norment AM
Year: 1997
Journal: J Exp Med
Title: Replacement of pre-T cell receptor signaling functions by the CD4 coreceptor.
Volume: 185
Issue: 1
Pages: 121-30
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Publication
8989204 | J:38055
First Author: Siddiqi MA
Year: 1997
Journal: J Acquir Immune Defic Syndr Hum Retrovirol
Title: Comparative analysis of the gp120-binding area of murine and human CD4 molecules.
Volume: 14
Issue: 1
Pages: 7-12
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Publication
12023391 | J:134936
First Author: Taneja V
Year: 2002
Journal: J Immunol
Title: CD4 and CD8 T cells in susceptibility/protection to collagen-induced arthritis in HLA-DQ8-transgenic mice: implications for rheumatoid arthritis.
Volume: 168
Issue: 11
Pages: 5867-75
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Publication
16034110 | J:107280
First Author: Grueter B
Year: 2005
Journal: J Immunol
Title: Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells.
Volume: 175
Issue: 3
Pages: 1694-705
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Publication
11305358 | J:68707
First Author: Seagal J
Year: 2001
Journal: Transgenic Res
Title: Use of human CD4 transgenic mice for studying immunogenicity of HIV-1 envelope protein gp120.
Volume: 10
Issue: 2
Pages: 113-20
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Publication
8955175 | J:37103
First Author: Kovalik JP
Year: 1996
Journal: J Immunol
Title: Rapid commitment to negative selection of a thymocyte line independent of CD4 co-engagement.
Volume: 157
Issue: 12
Pages: 5290-9
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Publication
22540016 | J:187196
First Author: Yamanaka D
Year: 2012
Journal: PLoS One
Title: The effect of enzymatically polymerised polyphenols on CD4 binding and cytokine production in murine splenocytes.
Volume: 7
Issue: 4
Pages: e36025
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Publication
24729613 | J:329783
First Author: Henson DM
Year: 2014
Journal: J Immunol
Title: A silencer-proximal intronic region is required for sustained CD4 expression in postselection thymocytes.
Volume: 192
Issue: 10
Pages: 4620-7
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Publication
8625961 | J:32579
First Author: Ismaili J
Year: 1996
Journal: Eur J Immunol
Title: CD4 and CD8 expression and T cell antigen receptor gene rearrangement in early intrathymic precursor cells.
Volume: 26
Issue: 4
Pages: 731-7
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Publication
30185787 | J:267930
First Author: Kojo S
Year: 2018
Journal: Nat Commun
Title: Runx-dependent and silencer-independent repression of a maturation enhancer in the Cd4 gene.
Volume: 9
Issue: 1
Pages: 3593
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Publication
24078700 | J:206233
First Author: Perkey E
Year: 2013
Journal: J Immunol
Title: Increased mammalian target of rapamycin complex 2 signaling promotes age-related decline in CD4 T cell signaling and function.
Volume: 191
Issue: 9
Pages: 4648-55
•
•
•
•
•
Publication
8512039 | J:115173
 
First Author: Miceli MC
Year: 1993
Journal: Adv Immunol
Title: Role of CD4 and CD8 in T cell activation and differentiation.
Volume: 53
Pages: 59-122
•
•
•
•
•
Publication
1901411 | J:113703
First Author: Miceli MC
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Adhesion versus coreceptor function of CD4 and CD8: role of the cytoplasmic tail in coreceptor activity.
Volume: 88
Issue: 7
Pages: 2623-7
•
•
•
•
•
Publication
16276482 | J:113771
First Author: Itoh Y
Year: 2005
Journal: Eur J Immunol
Title: Decreased CD4 expression by polarized T helper 2 cells contributes to suboptimal TCR-induced phosphorylation and reduced Ca2+ signaling.
Volume: 35
Issue: 11
Pages: 3187-95
•
•
•
•
•
Publication
17878349 | J:152351
First Author: Zhai Y
Year: 2007
Journal: J Immunol
Title: Defective alloreactive CD8 T cell function and memory response in allograft recipients in the absence of CD4 help.
Volume: 179
Issue: 7
Pages: 4529-34
•
•
•
•
•
Publication
7737281 | J:112983
First Author: Heemskerk MH
Year: 1995
Journal: Eur J Immunol
Title: Activation of virus-specific major histocompatibility complex class II-restricted CD8+ cytotoxic T cells in CD4-deficient mice.
Volume: 25
Issue: 4
Pages: 1109-12
•
•
•
•
•
Publication
7916297 | J:112988
First Author: Rahemtulla A
Year: 1994
Journal: Eur J Immunol
Title: Class II major histocompatibility complex-restricted T cell function in CD4-deficient mice.
Volume: 24
Issue: 9
Pages: 2213-8
•
•
•
•
•




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