Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2017 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
CD6 as a potential target for treating multiple sclerosis. |
Volume: |
114 |
Issue: |
10 |
Pages: |
2687-2692 |
|
•
•
•
•
•
|
Publication |
First Author: |
Enyindah-Asonye G |
Year: |
2017 |
Journal: |
J Biol Chem |
Title: |
CD6 Receptor Regulates Intestinal Ischemia/Reperfusion-induced Injury by Modulating Natural IgM-producing B1a Cell Self-renewal. |
Volume: |
292 |
Issue: |
2 |
Pages: |
661-671 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang L |
Year: |
2018 |
Journal: |
J Autoimmun |
Title: |
Targeting CD6 for the treatment of experimental autoimmune uveitis. |
Volume: |
90 |
|
Pages: |
84-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
CatalĂ C |
Year: |
2022 |
Journal: |
iScience |
Title: |
CD6 deficiency impairs early immune response to bacterial sepsis. |
Volume: |
25 |
Issue: |
10 |
Pages: |
105078 |
|
•
•
•
•
•
|
Publication |
First Author: |
Han J |
Year: |
2018 |
Journal: |
BMC Res Notes |
Title: |
CD6 expression has no effect on atherosclerosis in apolipoprotein E-deficient mice. |
Volume: |
11 |
Issue: |
1 |
Pages: |
229 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robinson WH |
Year: |
1995 |
Journal: |
J Immunol |
Title: |
Identification of a mouse protein homologous to the human CD6 T cell surface protein and sequence of the corresponding cDNA. |
Volume: |
155 |
Issue: |
10 |
Pages: |
4739-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wee S |
Year: |
1994 |
Journal: |
Cell Immunol |
Title: |
Characterization of a CD6 ligand(s) expressed on human- and murine-derived cell lines and murine lymphoid tissues. |
Volume: |
158 |
Issue: |
2 |
Pages: |
353-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Starling GC |
Year: |
1996 |
Journal: |
Eur J Immunol |
Title: |
Characterization of mouse CD6 with novel monoclonal antibodies which enhance the allogeneic mixed leukocyte reaction. |
Volume: |
26 |
Issue: |
4 |
Pages: |
738-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Orta-MascarĂł M |
Year: |
2016 |
Journal: |
J Exp Med |
Title: |
CD6 modulates thymocyte selection and peripheral T cell homeostasis. |
Volume: |
213 |
Issue: |
8 |
Pages: |
1387-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lecomte O |
Year: |
1996 |
Journal: |
Immunogenetics |
Title: |
Molecular linkage of the mouse CD5 and CD6 genes. |
Volume: |
44 |
Issue: |
5 |
Pages: |
385-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Whitney G |
Year: |
1995 |
Journal: |
Mol Immunol |
Title: |
Cloning and characterization of murine CD6. |
Volume: |
32 |
Issue: |
1 |
Pages: |
89-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
CasadĂł-Llombart S |
Year: |
2022 |
Journal: |
Front Immunol |
Title: |
Experimental and genetic evidence for the impact of CD5 and CD6 expression and variation in inflammatory bowel disease. |
Volume: |
13 |
|
Pages: |
966184 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mourglia-Ettlin G |
Year: |
2018 |
Journal: |
PLoS Negl Trop Dis |
Title: |
The ectodomains of the lymphocyte scavenger receptors CD5 and CD6 interact with tegumental antigens from Echinococcus granulosus sensu lato and protect mice against secondary cystic echinococcosis. |
Volume: |
12 |
Issue: |
11 |
Pages: |
e0006891 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roncagalli R |
Year: |
2014 |
Journal: |
Nat Immunol |
Title: |
Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub. |
Volume: |
15 |
Issue: |
4 |
Pages: |
384-392 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ozawa M |
Year: |
2022 |
Journal: |
Sci Rep |
Title: |
Efficient simultaneous double DNA knock-in in murine embryonic stem cells by CRISPR/Cas9 ribonucleoprotein-mediated circular plasmid targeting for generating gene-manipulated mice. |
Volume: |
12 |
Issue: |
1 |
Pages: |
21558 |
|
•
•
•
•
•
|
Publication |
First Author: |
Castro MA |
Year: |
2003 |
Journal: |
J Leukoc Biol |
Title: |
OX52 is the rat homologue of CD6: evidence for an effector function in the regulation of CD5 phosphorylation. |
Volume: |
73 |
Issue: |
1 |
Pages: |
183-90 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Pal A |
Year: |
1996 |
Journal: |
Immunol Lett |
Title: |
Mouse CD6: sequence of cDNA and expression of mRNA. |
Volume: |
49 |
Issue: |
1-2 |
Pages: |
133-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Enyindah-Asonye G |
Year: |
2017 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
CD318 is a ligand for CD6. |
Volume: |
114 |
Issue: |
33 |
Pages: |
E6912-E6921 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bowen MA |
Year: |
1997 |
Journal: |
Eur J Immunol |
Title: |
Characterization of mouse ALCAM (CD166): the CD6-binding domain is conserved in different homologs and mediates cross-species binding. |
Volume: |
27 |
Issue: |
6 |
Pages: |
1469-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu X |
Year: |
2016 |
Journal: |
BMC Immunol |
Title: |
Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. |
Volume: |
17 |
Issue: |
1 |
Pages: |
25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Allele |
Name: |
CD6 antigen; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
17 |
Description: |
T-cell differentiation antigen CD6 |
Type: |
chain |
End: |
665 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
665
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Allele |
Name: |
CD6 antigen; targeted mutation 1, Feng Lin |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
CD6 antigen; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Gimferrer I |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
The lymphocyte receptor CD6 interacts with syntenin-1, a scaffolding protein containing PDZ domains. |
Volume: |
175 |
Issue: |
3 |
Pages: |
1406-14 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Ichise H |
Year: |
2014 |
Journal: |
Genesis |
Title: |
The Cd6 gene as a permissive locus for targeted transgenesis in the mouse. |
Volume: |
52 |
Issue: |
5 |
Pages: |
440-50 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
665
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
586
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
626
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
327
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd6/Cd6 |
Background: |
D1.Cg-Cd6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Mori D |
Year: |
2021 |
Journal: |
J Exp Med |
Title: |
The T cell CD6 receptor operates a multitask signalosome with opposite functions in T cell activation. |
Volume: |
218 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hassan NJ |
Year: |
2006 |
Journal: |
Mol Cell Biol |
Title: |
CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76. |
Volume: |
26 |
Issue: |
17 |
Pages: |
6727-38 |
|
•
•
•
•
•
|
Allele |
Name: |
CD6 antigen; wild type |
|
|
|
•
•
•
•
•
|
Allele |
Name: |
CD6 antigen; endonuclease-mediated mutation 1, Masahito Ikawa |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, Inducible, Recombinase, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
CD6 antigen; endonuclease-mediated mutation 3, GemPharmatech |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Humanized sequence, Inserted expressed sequence, Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
CD6 antigen; targeted mutation 1, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
CD6 antigen; targeted mutation 2e, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
CD6 antigen; gene trap 378A6, Centre for Modeling Human Disease |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD6 antigen; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
CD6 antigen; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|