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Search results 1 to 100 out of 1899 for Cdk5

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
1020 | CDK5
Type: gene
Organism: human
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Gene
780236 | cdk5
Type: gene
Organism: frog, western clawed
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Gene
140908 | Cdk5
Type: gene
Organism: rat
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Gene
475537 | CDK5
Type: gene
Organism: dog, domestic
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Gene
463891 | CDK5
Type: gene
Organism: chimpanzee
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Gene
281066 | CDK5
Type: gene
Organism: cattle
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Gene
100190948 | CDK5
Type: gene
Organism: chicken
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Gene
65234 | cdk5
Type: gene
Organism: zebrafish
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Gene
714445 | CDK5
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:101765 | Cdk5
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10896159 | J:63117
First Author: Zukerberg LR
Year: 2000
Journal: Neuron
Title: Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth.
Volume: 26
Issue: 3
Pages: 633-46
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GXD Expression
GXD Expression
   
Probe: MGI:6452989
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271125
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6452991
Age: embryonic day 17.5
Specimen Label: 1A Cdk5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6452989
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271225
Pattern: Widespread
Stage: TS25
Assay Id: MGI:6452991
Age: embryonic day 17.5
Specimen Label: 1A Cdk5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6452989
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3270725
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6452991
Age: embryonic day 17.5
Specimen Label: 1A Cdk5
Detected: true
Specimen Num: 1
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Publication
23416045 | J:321065
First Author: Utreras E
Year: 2013
Journal: Neurochem Int
Title: Cdk5 regulates Rap1 activity.
Volume: 62
Issue: 6
Pages: 848-53
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Publication
27506619 | J:311324
First Author: Posada-Duque RA
Year: 2017
Journal: Cell Mol Life Sci
Title: CDK5 downregulation enhances synaptic plasticity.
Volume: 74
Issue: 1
Pages: 153-172
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Publication
33127972 | J:305001
First Author: Ouyang L
Year: 2020
Journal: Sci Rep
Title: p39-associated Cdk5 activity regulates dendritic morphogenesis.
Volume: 10
Issue: 1
Pages: 18746
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Publication
19017796 | J:142213
First Author: Lagace DC
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Cdk5 is essential for adult hippocampal neurogenesis.
Volume: 105
Issue: 47
Pages: 18567-71
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Publication
18691386 | J:140327
First Author: Sun KH
Year: 2008
Journal: J Neurochem
Title: Deregulated Cdk5 promotes oxidative stress and mitochondrial dysfunction.
Volume: 107
Issue: 1
Pages: 265-78
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Publication
18032670 | J:127641
First Author: Benavides DR
Year: 2007
Journal: J Neurosci
Title: Cdk5 modulates cocaine reward, motivation, and striatal neuron excitability.
Volume: 27
Issue: 47
Pages: 12967-76
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Publication
21389115 | J:182975
First Author: Chang KH
Year: 2011
Journal: Mol Biol Cell
Title: Nuclear envelope dispersion triggered by deregulated Cdk5 precedes neuronal death.
Volume: 22
Issue: 9
Pages: 1452-62
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Publication
12496365 | J:80587
First Author: Gao C
Year: 2002
Journal: Mol Cancer Res
Title: CDK5 regulates cell adhesion and migration in corneal epithelial cells.
Volume: 1
Issue: 1
Pages: 12-24
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Publication
28123016 | J:239154
First Author: Furusawa K
Year: 2017
Journal: J Neurosci
Title: Cdk5 Regulation of the GRAB-Mediated Rab8-Rab11 Cascade in Axon Outgrowth.
Volume: 37
Issue: 4
Pages: 790-806
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Publication
17341134 | J:245337
First Author: Cheung ZH
Year: 2007
Journal: PLoS Biol
Title: Cdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neurons.
Volume: 5
Issue: 4
Pages: e63
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Publication
21346193 | J:182989
First Author: Pallari HM
Year: 2011
Journal: Mol Biol Cell
Title: Nestin as a regulator of Cdk5 in differentiating myoblasts.
Volume: 22
Issue: 9
Pages: 1539-49
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Publication
17143272 | J:117343
First Author: Fu WY
Year: 2007
Journal: Nat Neurosci
Title: Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism.
Volume: 10
Issue: 1
Pages: 67-76
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Publication
31076103 | J:291495
First Author: Lee DK
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Cdk5 regulates N-cadherin-dependent neuronal migration during cortical development.
Volume: 514
Issue: 3
Pages: 645-652
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Publication
22451679 | J:185442
First Author: Utreras E
Year: 2012
Journal: J Biol Chem
Title: Transforming growth factor-β1 regulates Cdk5 activity in primary sensory neurons.
Volume: 287
Issue: 20
Pages: 16917-29
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Publication
27479491 | J:254508
First Author: Zheng YL
Year: 2016
Journal: PLoS One
Title: Knockdown of Expression of Cdk5 or p35 (a Cdk5 Activator) Results in Podocyte Apoptosis.
Volume: 11
Issue: 8
Pages: e0160252
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Publication
24607229 | J:248452
First Author: Plattner F
Year: 2014
Journal: Neuron
Title: Memory enhancement by targeting Cdk5 regulation of NR2B.
Volume: 81
Issue: 5
Pages: 1070-1083
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Publication
18998770 | J:145016
First Author: Jessberger S
Year: 2008
Journal: PLoS Biol
Title: Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus.
Volume: 6
Issue: 11
Pages: e272
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GXD Expression
GXD Expression
   
Probe: MGI:6169530
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189950
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Cdk5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6169530
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189950
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Cdk5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6169530
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189950
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Cdk5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6169530
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189950
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Cdk5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6169530
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189950
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Cdk5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6169530
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189950
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Cdk5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6169530
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189950
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Cdk5
Detected: true
Specimen Num: 7
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Protein
Q8K389
Organism: Mus musculus/domesticus
Length: 1822  
Fragment?: false
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Publication
32024968 | J:299432
First Author: NavaneethaKrishnan S
Year: 2020
Journal: Oncogene
Title: mPTP opening caused by Cdk5 loss is due to increased mitochondrial Ca2+ uptake.
Volume: 39
Issue: 13
Pages: 2797-2806
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Publication
27443506 | J:250150
 
First Author: Hernandez A
Year: 2016
Journal: Sci Rep
Title: Cdk5 Modulates Long-Term Synaptic Plasticity and Motor Learning in Dorsolateral Striatum.
Volume: 6
Pages: 29812
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Publication
26503494 | J:227913
 
First Author: Zhang P
Year: 2015
Journal: Nat Commun
Title: S-nitrosylation-dependent proteasomal degradation restrains Cdk5 activity to regulate hippocampal synaptic strength.
Volume: 6
Pages: 8665
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Publication
25331900 | J:216662
First Author: Chow HM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: CDK5 activator protein p25 preferentially binds and activates GSK3β.
Volume: 111
Issue: 45
Pages: E4887-95
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Publication
11163260 | J:66487
First Author: Niethammer M
Year: 2000
Journal: Neuron
Title: NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein.
Volume: 28
Issue: 3
Pages: 697-711
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Publication
26002103 | J:223930
First Author: Jahani-Asl A
Year: 2015
Journal: Hum Mol Genet
Title: CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death.
Volume: 24
Issue: 16
Pages: 4573-83
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Publication
10579588 | J:59870
First Author: Han SH
Year: 1999
Journal: Neuroscience
Title: Comparison of munc-18 and cdk5 expression in the nervous system during mouse embryogenesis.
Volume: 94
Issue: 3
Pages: 955-64
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Publication
31950315 | J:313185
First Author: Yang X
Year: 2020
Journal: Cell Mol Neurobiol
Title: Downregulation of CDK5 Restores Sevoflurane-Induced Cognitive Dysfunction by Promoting SIRT1-Mediated Autophagy.
Volume: 40
Issue: 6
Pages: 955-965
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Publication
24142862 | J:219260
First Author: Rakić S
Year: 2015
Journal: Cereb Cortex
Title: Cdk5 phosphorylation of ErbB4 is required for tangential migration of cortical interneurons.
Volume: 25
Issue: 4
Pages: 991-1003
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Publication
21984943 | J:274087
First Author: Guan JS
Year: 2011
Journal: PLoS One
Title: Cdk5 is required for memory function and hippocampal plasticity via the cAMP signaling pathway.
Volume: 6
Issue: 9
Pages: e25735
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Publication
19017804 | J:206784
First Author: Meyer DA
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology.
Volume: 105
Issue: 47
Pages: 18561-6
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Publication
8275715 | J:16272
First Author: Demetrick DJ
Year: 1994
Journal: Cytogenet Cell Genet
Title: Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes.
Volume: 66
Issue: 1
Pages: 72-4
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Publication
18042622 | J:130449
First Author: Miyamoto Y
Year: 2007
Journal: J Cell Sci
Title: Cdk5 regulates differentiation of oligodendrocyte precursor cells through the direct phosphorylation of paxillin.
Volume: 120
Issue: Pt 24
Pages: 4355-66
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Publication
18325333 | J:201251
First Author: Lin S
Year: 2008
Journal: FEBS Lett
Title: CDK5 activator p35 downregulates E-cadherin precursor independently of CDK5.
Volume: 582
Issue: 8
Pages: 1197-202
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Publication
11276227 | J:114070
First Author: Fu AK
Year: 2001
Journal: Nat Neurosci
Title: Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction.
Volume: 4
Issue: 4
Pages: 374-81
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Publication
17121546 | J:123393
First Author: Horiuchi Y
Year: 2006
Journal: Genes Cells
Title: Identifying novel substrates for mouse Cdk5 kinase using the yeast Saccharomyces cerevisiae.
Volume: 11
Issue: 12
Pages: 1393-404
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Publication
20392944 | J:159853
First Author: Zhang J
Year: 2010
Journal: J Neurosci
Title: Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex.
Volume: 30
Issue: 15
Pages: 5219-28
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Publication
20977891 | J:170746
 
First Author: Antoniou X
Year: 2011
Journal: Brain Res
Title: Cdk5 interacts with Hif-1α in neurons: a new hypoxic signalling mechanism?
Volume: 1381
Pages: 1-10
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Publication
26027726 | J:223043
 
First Author: Liebl J
Year: 2015
Journal: Nat Commun
Title: Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2.
Volume: 6
Pages: 7274
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Publication
21944720 | J:178882
First Author: Odajima J
Year: 2011
Journal: Dev Cell
Title: Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation.
Volume: 21
Issue: 4
Pages: 655-68
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Publication
15067135 | J:89561
First Author: Hirasawa M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Perinatal abrogation of Cdk5 expression in brain results in neuronal migration defects.
Volume: 101
Issue: 16
Pages: 6249-54
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Publication
26930193 | J:259816
First Author: Shu Y
Year: 2016
Journal: PLoS One
Title: Parkinson-Related LRRK2 Mutation R1628P Enables Cdk5 Phosphorylation of LRRK2 and Upregulates Its Kinase Activity.
Volume: 11
Issue: 3
Pages: e0149739
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Publication
24768698 | J:216629
First Author: Zhang Y
Year: 2014
Journal: Exp Cell Res
Title: High glucose increases Cdk5 activity in podocytes via transforming growth factor-β1 signaling pathway.
Volume: 326
Issue: 2
Pages: 219-29
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Publication
14642273 | J:104240
First Author: Cruz JC
Year: 2003
Journal: Neuron
Title: Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles.
Volume: 40
Issue: 3
Pages: 471-83
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Publication
15280426 | J:92070
First Author: Gao CY
Year: 2004
Journal: J Cell Sci
Title: Cdk5 regulates activation and localization of Src during corneal epithelial wound closure.
Volume: 117
Issue: Pt 18
Pages: 4089-98
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Publication
11343650 | J:69136
First Author: Nguyen MD
Year: 2001
Journal: Neuron
Title: Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions.
Volume: 30
Issue: 1
Pages: 135-47
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Publication
31699822 | J:285057
 
First Author: Liu XX
Year: 2020
Journal: J Exp Med
Title: Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis.
Volume: 217
Issue: 1
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Publication
16021178 | J:121028
First Author: Lin L
Year: 2006
Journal: Cell Death Differ
Title: p53, Apaf-1, caspase-3, and -9 are dispensable for Cdk5 activation during cell death.
Volume: 13
Issue: 1
Pages: 141-50
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Publication
26602020 | J:259839
First Author: Na YR
Year: 2015
Journal: Sci Signal
Title: The early synthesis of p35 and activation of CDK5 in LPS-stimulated macrophages suppresses interleukin-10 production.
Volume: 8
Issue: 404
Pages: ra121
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Publication
18550843 | J:137191
First Author: Zhang J
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Nuclear localization of Cdk5 is a key determinant in the postmitotic state of neurons.
Volume: 105
Issue: 25
Pages: 8772-7
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Publication
37223477 | J:359533
 
First Author: Tong C
Year: 2023
Journal: Research (Wash D C)
Title: Striatal CDK5 Regulates Cholinergic Neuron Activation and Dyskinesia-like Behaviors through BK Channels.
Volume: 6
Pages: 0121
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Publication
8891282 | J:35360
First Author: Ino H
Year: 1996
Journal: Brain Res
Title: Intracellular localization of cyclin-dependent kinase 5 (CDK5) in mouse neuron: CDK5 is located in both nucleus and cytoplasm.
Volume: 732
Issue: 1-2
Pages: 179-85
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Publication
25952543 | J:319080
First Author: Qi GJ
Year: 2016
Journal: Mol Neurobiol
Title: Phosphorylation of Connexin 43 by Cdk5 Modulates Neuronal Migration During Embryonic Brain Development.
Volume: 53
Issue: 5
Pages: 2969-2982
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Publication
21210220 | J:284799
First Author: He X
Year: 2011
Journal: Neurochem Res
Title: Hypomyelination phenotype caused by impaired differentiation of oligodendrocytes in Emx1-cre mediated Cdk5 conditional knockout mice.
Volume: 36
Issue: 7
Pages: 1293-303
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Publication
18054859 | J:169741
First Author: Samuels BA
Year: 2007
Journal: Neuron
Title: Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK.
Volume: 56
Issue: 5
Pages: 823-37
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Publication
24658276 | J:214155
First Author: Contreras-Vallejos E
Year: 2014
Journal: PLoS One
Title: Searching for novel Cdk5 substrates in brain by comparative phosphoproteomics of wild type and Cdk5-/- mice.
Volume: 9
Issue: 3
Pages: e90363
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Publication
27273428 | J:319915
First Author: Uribe-Arias A
Year: 2016
Journal: J Neurochem
Title: p120-catenin is necessary for neuroprotection induced by CDK5 silencing in models of Alzheimer's disease.
Volume: 138
Issue: 4
Pages: 624-39
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Publication
22899714 | J:199756
First Author: Chang KH
Year: 2012
Journal: J Cell Sci
Title: Deregulated Cdk5 triggers aberrant activation of cell cycle kinases and phosphatases inducing neuronal death.
Volume: 125
Issue: Pt 21
Pages: 5124-37
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Publication
24495352 | J:206950
 
First Author: Utreras E
Year: 2014
Journal: J Neuroinflammation
Title: Suppression of neuroinflammation in forebrain-specific Cdk5 conditional knockout mice by PPARγ agonist improves neuronal loss and early lethality.
Volume: 11
Pages: 28
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Publication
22467861 | J:197795
First Author: Asada A
Year: 2012
Journal: J Cell Sci
Title: Phosphorylation of p35 and p39 by Cdk5 determines the subcellular location of the holokinase in a phosphorylation-site-specific manner.
Volume: 125
Issue: Pt 14
Pages: 3421-9
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Publication
25864429 | J:239283
First Author: Posada-Duque RA
Year: 2015
Journal: J Neurochem
Title: p35 and Rac1 underlie the neuroprotection and cognitive improvement induced by CDK5 silencing.
Volume: 134
Issue: 2
Pages: 354-70
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Publication
17591690 | J:124168
First Author: Lee JH
Year: 2007
Journal: J Cell Sci
Title: Stabilization and activation of p53 induced by Cdk5 contributes to neuronal cell death.
Volume: 120
Issue: Pt 13
Pages: 2259-71
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Publication
22398430 | J:316721
First Author: Fu AK
Year: 2013
Journal: Neurosignals
Title: Cdk5 phosphorylates a component of the HDAC complex and regulates histone acetylation during neuronal cell death.
Volume: 21
Issue: 1-2
Pages: 55-60
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Publication
12941275 | J:85235
First Author: Xie Z
Year: 2003
Journal: Cell
Title: Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration.
Volume: 114
Issue: 4
Pages: 469-82
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Publication
17492640 | J:132890
First Author: Yip YP
Year: 2007
Journal: J Comp Neurol
Title: Cdk5 selectively affects the migration of different populations of neurons in the developing spinal cord.
Volume: 503
Issue: 2
Pages: 297-307
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Publication
27480591 | J:261117
First Author: Sasamoto K
Year: 2017
Journal: Dev Neurobiol
Title: Cdk5 is required for the positioning and survival of GABAergic neurons in developing mouse striatum.
Volume: 77
Issue: 4
Pages: 483-492
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Publication
25309427 | J:288953
 
First Author: Castro-Alvarez JF
Year: 2014
Journal: Front Aging Neurosci
Title: Long- and short-term CDK5 knockdown prevents spatial memory dysfunction and tau pathology of triple transgenic Alzheimer's mice.
Volume: 6
Pages: 243
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Publication
29729246 | J:269994
 
First Author: Luo F
Year: 2018
Journal: Exp Neurol
Title: Oligodendrocyte-specific loss of Cdk5 disrupts the architecture of nodes of Ranvier as well as learning and memory.
Volume: 306
Pages: 92-104
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Publication
12372285 | J:107755
First Author: Sasaki Y
Year: 2002
Journal: Neuron
Title: Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex.
Volume: 35
Issue: 5
Pages: 907-20
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GXD Expression
GXD Expression
 
Probe: MGI:7608354
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3265122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7608366
Age: embryonic day 14.5
Note: Diminished levels of cell death observed in the Hm mutant limb correlated with diminished Cdk5 signal.
Specimen Label: 3-4
Detected: true
Specimen Num: 2
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Publication
17295212 | J:156100
First Author: He Y
Year: 2007
Journal: Glia
Title: The presence of active Cdk5 associated with p35 in astrocytes and its important role in process elongation of scratched astrocyte.
Volume: 55
Issue: 6
Pages: 573-83
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Publication
11162238 | J:67763
First Author: Van den Haute C
Year: 2001
Journal: Neurobiol Dis
Title: Coexpression of human cdk5 and its activator p35 with human protein tau in neurons in brain of triple transgenic mice.
Volume: 8
Issue: 1
Pages: 32-44
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Publication
23982957 | J:319015
First Author: Lee MH
Year: 2013
Journal: J Neurovirol
Title: Impaired neurogenesis and neurite outgrowth in an HIV-gp120 transgenic model is reversed by exercise via BDNF production and Cdk5 regulation.
Volume: 19
Issue: 5
Pages: 418-31
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Publication
25183872 | J:319078
First Author: Nishimura YV
Year: 2014
Journal: Development
Title: Cdk5 and its substrates, Dcx and p27kip1, regulate cytoplasmic dilation formation and nuclear elongation in migrating neurons.
Volume: 141
Issue: 18
Pages: 3540-50
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Publication
24085300 | J:205917
First Author: Saito T
Year: 2013
Journal: J Biol Chem
Title: Structural basis for the different stability and activity between the Cdk5 complexes with p35 and p39 activators.
Volume: 288
Issue: 45
Pages: 32433-9
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Publication
27807169 | J:236773
First Author: Li W
Year: 2016
Journal: J Neurosci
Title: p39 Is Responsible for Increasing Cdk5 Activity during Postnatal Neuron Differentiation and Governs Neuronal Network Formation and Epileptic Responses.
Volume: 36
Issue: 44
Pages: 11283-11294
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Publication
22223639 | J:182773
First Author: Sadleir KR
Year: 2012
Journal: J Biol Chem
Title: Cdk5 protein inhibition and Aβ42 increase BACE1 protein level in primary neurons by a post-transcriptional mechanism: implications of CDK5 as a therapeutic target for Alzheimer disease.
Volume: 287
Issue: 10
Pages: 7224-35
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Publication
37976261 | J:355053
First Author: Miller N
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Mitigating aberrant Cdk5 activation alleviates mitochondrial defects and motor neuron disease symptoms in spinal muscular atrophy.
Volume: 120
Issue: 47
Pages: e2300308120
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Publication
21151568 | J:167737
First Author: Ohara-Imaizumi M
Year: 2010
Journal: PLoS One
Title: Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis.
Volume: 5
Issue: 12
Pages: e15553
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Publication
35527277 | J:345507
First Author: Chen D
Year: 2022
Journal: Transl Neurodegener
Title: Melatonin ameliorates tau-related pathology via the miR-504-3p and CDK5 axis in Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 27
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Publication
27053712 | J:236705
First Author: Husson H
Year: 2016
Journal: Hum Mol Genet
Title: Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.
Volume: 25
Issue: 11
Pages: 2245-2255
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