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Search results 1 to 100 out of 312 for Cdk8

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
1024 | CDK8
Type: gene
Organism: human
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Gene
394856 | cdk8
Type: gene
Organism: frog, western clawed
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Gene
486035 | CDK8
Type: gene
Organism: dog, domestic
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Gene
452501 | CDK8
Type: gene
Organism: chimpanzee
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Gene
498140 | Cdk8
Type: gene
Organism: rat
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Gene
507149 | CDK8
Type: gene
Organism: cattle
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Gene
428080 | CDK8
Type: gene
Organism: chicken
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Gene
373868 | cdk8
Type: gene
Organism: zebrafish
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Gene
709761 | CDK8
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1196224 | Cdk8
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17620419 | J:125327
First Author: Westerling T
Year: 2007
Journal: Mol Cell Biol
Title: Cdk8 is essential for preimplantation mouse development.
Volume: 27
Issue: 17
Pages: 6177-82
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Publication
- | J:332956
     
First Author: Fisher D
Year: 2013
Journal: MGI Direct Data Submission
Title: Direct Data Submission Cdk8 Allele.
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Publication
29386186 | J:275519
First Author: Witalisz-Siepracka A
Year: 2018
Journal: Cancer Immunol Res
Title: NK Cell-Specific CDK8 Deletion Enhances Antitumor Responses.
Volume: 6
Issue: 4
Pages: 458-466
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Publication
31628323 | J:280695
First Author: Menzl I
Year: 2019
Journal: Nat Commun
Title: A kinase-independent role for CDK8 in BCR-ABL1+ leukemia.
Volume: 10
Issue: 1
Pages: 4741
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Publication
35777359 | J:328686
First Author: Yamada T
Year: 2022
Journal: Stem Cell Reports
Title: The role of CDK8 in mesenchymal stem cells in controlling osteoclastogenesis and bone homeostasis.
Volume: 17
Issue: 7
Pages: 1576-1588
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Publication
31495563 | J:281559
First Author: Steinparzer I
Year: 2019
Journal: Mol Cell
Title: Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions.
Volume: 76
Issue: 3
Pages: 485-499.e8
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Publication
23352233 | J:193482
First Author: Bancerek J
Year: 2013
Journal: Immunity
Title: CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response.
Volume: 38
Issue: 2
Pages: 250-62
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Publication
36006697 | J:331423
 
First Author: Dannappel MV
Year: 2022
Journal: J Clin Invest
Title: CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF.
Volume: 132
Issue: 20
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Publication
31509750 | J:281075
First Author: Xue J
Year: 2019
Journal: Cell Rep
Title: CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic β Cells.
Volume: 28
Issue: 11
Pages: 2892-2904.e7
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Publication
26235356 | J:227730
First Author: McCleland ML
Year: 2015
Journal: J Pathol
Title: Cdk8 deletion in the Apc(Min) murine tumour model represses EZH2 activity and accelerates tumourigenesis.
Volume: 237
Issue: 4
Pages: 508-19
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Publication
36545778 | J:341371
First Author: Prieto S
Year: 2023
Journal: EMBO Rep
Title: CDK8 and CDK19 act redundantly to control the CFTR pathway in the intestinal epithelium.
Volume: 24
Issue: 2
Pages: e54261
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Publication
32439758 | J:290852
 
First Author: Postlmayr A
Year: 2020
Journal: Development
Title: Cdk8 is required for establishment of H3K27me3 and gene repression by Xist and mouse development.
Volume: 147
Issue: 11
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Publication
31945608 | J:298406
 
First Author: Xi X
Year: 2020
Journal: Int Immunopharmacol
Title: MiR-297 alleviates LPS-induced A549 cell and mice lung injury via targeting cyclin dependent kinase 8.
Volume: 80
Pages: 106197
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Publication
25818643 | J:221861
 
First Author: Xu D
Year: 2015
Journal: Nat Commun
Title: Skp2-macroH2A1-CDK8 axis orchestrates G2/M transition and tumorigenesis.
Volume: 6
Pages: 6641
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Publication
25344755 | J:217695
First Author: Li N
Year: 2014
Journal: Nat Cell Biol
Title: Cyclin C is a haploinsufficient tumour suppressor.
Volume: 16
Issue: 11
Pages: 1080-91
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Publication
32989249 | J:307869
First Author: Lynch CJ
Year: 2020
Journal: Nat Cell Biol
Title: Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases.
Volume: 22
Issue: 10
Pages: 1223-1238
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Publication
19914168 | J:157018
First Author: Alarcón C
Year: 2009
Journal: Cell
Title: Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways.
Volume: 139
Issue: 4
Pages: 757-69
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Publication
22869755 | J:188596
First Author: Porter DC
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.
Volume: 109
Issue: 34
Pages: 13799-804
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Publication
26042770 | J:233814
First Author: Feng D
Year: 2015
Journal: PLoS One
Title: mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC).
Volume: 10
Issue: 6
Pages: e0126240
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Protein Coding Gene
MGP_CAROLIEiJ_G0028025 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030375 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030348 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030275 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030357 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030071 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1196224 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030049 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030193 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030147 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030280 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0030183 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030842 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029187 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029550 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024591 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029023 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:7645730
Assay Type: RT-PCR
Annotation Date: 2024-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718522
Stage: TS22
Assay Id: MGI:7645805
Age: embryonic day 14.5
Image: 3
Specimen Label: E14.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7645730
Assay Type: RT-PCR
Annotation Date: 2024-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718526
Stage: TS26
Assay Id: MGI:7645805
Age: embryonic day 18.5
Image: 3
Specimen Label: E18.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7645730
Assay Type: RT-PCR
Annotation Date: 2024-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718528
Stage: TS28
Assay Id: MGI:7645805
Age: postnatal day 5
Image: 3
Specimen Label: P5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7645730
Assay Type: RT-PCR
Annotation Date: 2024-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1718528
Stage: TS28
Assay Id: MGI:7645805
Age: postnatal day 40
Image: 3
Specimen Label: P40
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7645730
Assay Type: RT-PCR
Annotation Date: 2024-06-09
Strength: Present
Sex: Male
Emaps: EMAPS:3586628
Stage: TS28
Assay Id: MGI:7645819
Age: postnatal month 3
Image: 6
Specimen Label: 3 mon
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7645730
Assay Type: RT-PCR
Annotation Date: 2024-06-09
Strength: Present
Sex: Male
Emaps: EMAPS:3586628
Stage: TS28
Assay Id: MGI:7645819
Age: postnatal month 24
Image: 6
Specimen Label: 24 mon
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7645743
Assay Type: Western blot
Annotation Date: 2024-06-09
Strength: Present
Sex: Male
Emaps: EMAPS:3586628
Stage: TS28
Assay Id: MGI:7645829
Age: postnatal month 3
Image: 6
Specimen Label: 3 mon
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7645743
Assay Type: Western blot
Annotation Date: 2024-06-09
Strength: Present
Sex: Male
Emaps: EMAPS:3586628
Stage: TS28
Assay Id: MGI:7645829
Age: postnatal month 24
Image: 6
Specimen Label: 24 mon
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7645730
Assay Type: RT-PCR
Annotation Date: 2024-06-09
Strength: Present
Sex: Male
Emaps: EMAPS:3586628
Stage: TS28
Assay Id: MGI:7645852
Age: postnatal week 8-10
Image: 7
Specimen Label: Wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7645730
Assay Type: RT-PCR
Annotation Date: 2024-06-09
Strength: Present
Sex: Male
Emaps: EMAPS:3586628
Stage: TS28
Assay Id: MGI:7645852
Age: postnatal week 8-10
Image: 7
Specimen Label: mdx
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2007-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:3761007
Age: embryonic day 11.5
Note: Widespread ubiquitous expression.
Specimen Label: 1F
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7608360
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3265122
Stage: TS22
Assay Id: MGI:7608373
Age: embryonic day 14.5
Specimen Label: 2-8
Detected: false
Specimen Num: 1
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Publication
23933255 | J:201893
First Author: Putz EM
Year: 2013
Journal: Cell Rep
Title: CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance.
Volume: 4
Issue: 3
Pages: 437-44
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Publication
14638676 | J:88488
First Author: Tomomori-Sato C
Year: 2004
Journal: J Biol Chem
Title: A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2.
Volume: 279
Issue: 7
Pages: 5846-51
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Publication
16109376 | J:101015
First Author: Jang MK
Year: 2005
Journal: Mol Cell
Title: The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.
Volume: 19
Issue: 4
Pages: 523-34
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Publication
9438340 | J:45218
First Author: Ahuja HS
Year: 1997
Journal: Dev Genet
Title: Association of cyclin-dependent kinase 5 and its activator p35 with apoptotic cell death.
Volume: 21
Issue: 4
Pages: 258-67
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Publication
27570068 | J:239012
First Author: Aranda-Orgilles B
Year: 2016
Journal: Cell Stem Cell
Title: MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.
Volume: 19
Issue: 6
Pages: 784-799
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Publication
32248761 | J:304183
First Author: Ponce JM
Year: 2020
Journal: J Am Heart Assoc
Title: Stress-Induced Cyclin C Translocation Regulates Cardiac Mitochondrial Dynamics.
Volume: 9
Issue: 7
Pages: e014366
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Protein
Q5U427
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: true
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Publication
15340084 | J:92973
First Author: Malik S
Year: 2004
Journal: Mol Cell Biol
Title: Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors.
Volume: 24
Issue: 18
Pages: 8244-54
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Publication
32731332 | J:307678
 
First Author: Campbell GJ
Year: 2020
Journal: Int J Mol Sci
Title: The Role of CDKs and CDKIs in Murine Development.
Volume: 21
Issue: 15
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Publication
38690566 | J:347774
 
First Author: Kolonay DW
Year: 2024
Journal: Front Cell Dev Biol
Title: Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease.
Volume: 12
Pages: 1331563
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Publication
22898775 | J:187715
First Author: Xie L
Year: 2012
Journal: Dev Cell
Title: Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation.
Volume: 23
Issue: 2
Pages: 280-91
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Publication
20720539 | J:164442
First Author: Kagey MH
Year: 2010
Journal: Nature
Title: Mediator and cohesin connect gene expression and chromatin architecture.
Volume: 467
Issue: 7314
Pages: 430-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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