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Search results 1 to 100 out of 303 for Cenpj

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
486055 | CENPJ
Type: gene
Organism: dog, domestic
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Gene
467235 | CENPJ
Type: gene
Organism: chimpanzee
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Gene
613543 | CENPJ
Type: gene
Organism: cattle
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Gene
418960 | CENPJ
Type: gene
Organism: chicken
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Gene
721498 | CENPJ
Type: gene
Organism: macaque, rhesus
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GXD Expression
GXD Expression
 
Probe: MGI:7547283
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267928
Stage: TS28
Assay Id: MGI:7547332
Age: postnatal adult
Image: 1D Cenpj CenpjCKO
Note: No expression in centrosomes in ventricular zone.
Specimen Label: 1D Cenpj CenpjCKO
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7547283
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7547332
Age: postnatal adult
Image: 1D Cenpj Cenpj+/+
Note: n
Specimen Label: 1D Cenpj Cenpj+/+
Detected: true
Specimen Num: 1
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Publication
30626697 | J:273130
First Author: Ding W
Year: 2019
Journal: J Neurosci
Title: Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.
Volume: 39
Issue: 11
Pages: 1994-2010
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Publication
32803714 | J:332091
First Author: Ding W
Year: 2021
Journal: Sci China Life Sci
Title: Loss of the centrosomal protein Cenpj leads to dysfunction of the hypothalamus and obesity in mice.
Volume: 64
Issue: 3
Pages: 419-433
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HT Experiment
GSE110416 | RNA-seq analysis of the transcriptome changes on Cenpj depletion cortices at E15.5
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
15793586 | -
First Author: Bond J
Year: 2005
Journal: Nat Genet
Title: A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size.
Volume: 37
Issue: 4
Pages: 353-5
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Gene
55835 | CPAP
Type: gene
Organism: human
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HT Experiment
GSE139640 | Loss of the centrosomal protein Cenpj leads to dysfunction of the hypothalamus and obesity in mice
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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DO Term
DOID:0070010 | Seckel syndrome 4
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Protein Coding Gene
MGI:2684927 | Cpap
Type: protein_coding_gene
Organism: mouse, laboratory
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DO Term
DOID:0070290 | primary autosomal recessive microcephaly 6
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Publication
25753651 | J:221891
 
First Author: Garcez PP
Year: 2015
Journal: Nat Commun
Title: Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1.
Volume: 6
Pages: 6474
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Publication
23166506 | J:194085
First Author: McIntyre RE
Year: 2012
Journal: PLoS Genet
Title: Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.
Volume: 8
Issue: 11
Pages: e1003022
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Protein
Q8C5V8
Organism: Mus musculus/domesticus
Length: 958  
Fragment?: false
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Protein
Q5FW83
Organism: Mus musculus/domesticus
Length: 291  
Fragment?: false
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Protein
A0A5H1ZRM1
Organism: Mus musculus/domesticus
Length: 381  
Fragment?: true
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Protein
A2N6K8
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: true
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Protein
A0A1L1SUD9
Organism: Mus musculus/domesticus
Length: 2163  
Fragment?: false
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Protein
D3Z3T8
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: true
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Protein
A0A2I3BPI0
Organism: Mus musculus/domesticus
Length: 2202  
Fragment?: false
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Protein
A0A5H1ZRN0
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: true
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Protein
A0A3B2W411
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: true
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Protein
A0A3B2WCB2
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: true
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Publication
20531387 | -
First Author: Chang J
Year: 2010
Journal: EMBO J
Title: PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle.
Volume: 29
Issue: 14
Pages: 2395-406
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Publication
14586771 | -
First Author: Chen Z
Year: 2003
Journal: J Hum Genet
Title: Identification of a novel liver-specific expressed gene, TCP10L, encoding a human leucine zipper protein with transcription inhibition activity.
Volume: 48
Issue: 11
Pages: 556-63
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Publication
24565846 | -
First Author: Zuo J
Year: 2014
Journal: Biochem Biophys Res Commun
Title: TCP10L acts as a tumor suppressor by inhibiting cell proliferation in hepatocellular carcinoma.
Volume: 446
Issue: 1
Pages: 61-7
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Publication
15615782 | -
First Author: Patel H
Year: 2005
Journal: J Cell Sci
Title: Activity and subcellular compartmentalization of peroxisome proliferator-activated receptor alpha are altered by the centrosome-associated protein CAP350.
Volume: 118
Issue: Pt 1
Pages: 175-86
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Publication
17878239 | -
First Author: Hoppeler-Lebel A
Year: 2007
Journal: J Cell Sci
Title: Centrosomal CAP350 protein stabilises microtubules associated with the Golgi complex.
Volume: 120
Issue: Pt 18
Pages: 3299-308
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Publication
16314388 | -
First Author: Yan X
Year: 2006
Journal: Mol Biol Cell
Title: A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring.
Volume: 17
Issue: 2
Pages: 634-44
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Protein Domain
IPR028750 | CEP350
Type: Family
Description: Centrosome-associated protein 350 (CEP350 or CAP350) plays an essential role in centriole growth by stabilising a procentriolar seed composed of, at least, SASS6 and CENPJ []. It is required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network []. It also stabilises Golgi-associated microtubules and maintains a continuous pericentrosomal Golgi ribbon [].CEP350 possesses a CAP-Gly domain which is targeted to the centrosome or the Golgi-like network and binds microtubules through an N-terminal basic region [].
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Protein Domain
IPR026581 | TCP10_fam
Type: Family
Description: Proteins in this family include T-complex protein 10 and centromere protein J (CENPJ). T-complex is involved in spermatogenesis in mice []. T-complex protein 10A homologue 2 (also known as TCP10L) may be involved in transcriptional regulation and has in vitro transcription inhibition activity []. It acts as a tumour suppressor in hepatocellular carcinoma (HCC) cells []. CENPJ not only inhibits microtubule nucleation from the centrosome, but also depolymerises taxol-stabilised microtubules [, , ].
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Protein
Q62183
Organism: Mus musculus/domesticus
Length: 418  
Fragment?: false
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Protein
A2N6L1
Organism: Mus musculus/domesticus
Length: 39  
Fragment?: true
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Protein
E9PYJ0
Organism: Mus musculus/domesticus
Length: 438  
Fragment?: false
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Protein
Q8C5S9
Organism: Mus musculus/domesticus
Length: 438  
Fragment?: false
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Protein
A2N6K9
Organism: Mus musculus/domesticus
Length: 416  
Fragment?: true
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Protein
Q62184
Organism: Mus musculus/domesticus
Length: 438  
Fragment?: false
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Protein
L7N265
Organism: Mus musculus/domesticus
Length: 401  
Fragment?: true
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Protein
A2N6L0
Organism: Mus musculus/domesticus
Length: 401  
Fragment?: true
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Protein
Q80YU2
Organism: Mus musculus/domesticus
Length: 438  
Fragment?: false
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Protein
B2RUN1
Organism: Mus musculus/domesticus
Length: 438  
Fragment?: false
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Protein
Q3V169
Organism: Mus musculus/domesticus
Length: 362  
Fragment?: false
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Protein
E9Q2X0
Organism: Mus musculus/domesticus
Length: 420  
Fragment?: false
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Protein
D3Z452
Organism: Mus musculus/domesticus
Length: 401  
Fragment?: true
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Protein
O35706
Organism: Mus musculus/domesticus
Length: 401  
Fragment?: true
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Protein
E9Q046
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
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Protein
A0A2R8VK38
Organism: Mus musculus/domesticus
Length: 439  
Fragment?: true
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Protein
Q99206
Organism: Mus musculus/domesticus
Length: 438  
Fragment?: false
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Protein
A0A3B2WCQ3
Organism: Mus musculus/domesticus
Length: 391  
Fragment?: false
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Protein
O35703
Organism: Mus musculus/domesticus
Length: 438  
Fragment?: false
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Protein
A0A3B2WCL2
Organism: Mus musculus/domesticus
Length: 363  
Fragment?: false
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Protein
Q80W76
Organism: Mus musculus/domesticus
Length: 438  
Fragment?: false
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Protein
Q8C641
Organism: Mus musculus/domesticus
Length: 457  
Fragment?: false
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Publication
12068715 | -
First Author: Safronova LD
Year: 2002
Journal: Ontogenez
Title: [Sterility of males determined by functional features of the mouse spermatozoa bearing t-complex].
Volume: 33
Issue: 3
Pages: 165-9
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Publication
15047868 | -
First Author: Hung LY
Year: 2004
Journal: Mol Biol Cell
Title: Identification of a novel microtubule-destabilizing motif in CPAP that binds to tubulin heterodimers and inhibits microtubule assembly.
Volume: 15
Issue: 6
Pages: 2697-706
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Protein
Q569L8
Organism: Mus musculus/domesticus
Length: 1344  
Fragment?: false
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Protein
E9Q309
Organism: Mus musculus/domesticus
Length: 3095  
Fragment?: false
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Protein
Q3UWL2
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: true
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Publication
17681131 | -
First Author: Kleylein-Sohn J
Year: 2007
Journal: Dev Cell
Title: Plk4-induced centriole biogenesis in human cells.
Volume: 13
Issue: 2
Pages: 190-202
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Protein Coding Gene
MGP_CAROLIEiJ_G0019338 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021394 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021353 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021329 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021356 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021137 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2684927 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021796 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020656 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021104 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021224 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021207 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021299 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021231 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021822 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020399 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020708 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030356 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020229 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
23213448 | J:184889
First Author: Wu KS
Year: 2012
Journal: Biol Open
Title: CPAP is required for cilia formation in neuronal cells.
Volume: 1
Issue: 6
Pages: 559-65
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GXD Expression
GXD Expression
   
Probe: MGI:7547283
Assay Type: Western blot
Annotation Date: 2023-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:7547294
Age: embryonic day 15.5
Image: 1
Specimen Label: Cenpj+/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7547283
Assay Type: Western blot
Annotation Date: 2023-11-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:7547294
Age: embryonic day 15.5
Image: 1
Specimen Label: CenpjCKO
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7547261
Assay Type: RT-PCR
Annotation Date: 2023-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:7547295
Age: embryonic day 15.5
Image: 6
Specimen Label: Cenpj+/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7547261
Assay Type: RT-PCR
Annotation Date: 2023-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:7547295
Age: embryonic day 15.5
Image: 6
Specimen Label: CenpjCKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3265722
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540355
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3265722
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823808
Age: embryonic day 14.5
Image: euxassay_011118_09
Specimen Label: euxassay_011118_09
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:3265722
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823808
Age: embryonic day 14.5
Image: euxassay_011118_10
Specimen Label: euxassay_011118_10
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:3265722
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823808
Age: embryonic day 14.5
Image: euxassay_011118_11
Specimen Label: euxassay_011118_11
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:3265722
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823808
Age: embryonic day 14.5
Image: euxassay_011118_12
Specimen Label: euxassay_011118_12
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:3265722
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823808
Age: embryonic day 14.5
Image: euxassay_011118_13
Specimen Label: euxassay_011118_13
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:3265722
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823808
Age: embryonic day 14.5
Image: euxassay_011118_14
Specimen Label: euxassay_011118_14
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:3265722
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823808
Age: embryonic day 14.5
Image: euxassay_011118_17
Specimen Label: euxassay_011118_17
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
 
Probe: MGI:3265722
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823808
Age: embryonic day 14.5
Image: euxassay_011118_18
Specimen Label: euxassay_011118_18
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
 
Probe: MGI:3265722
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823808
Age: embryonic day 14.5
Image: euxassay_011118_19
Specimen Label: euxassay_011118_19
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Probe: MGI:3265722
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823808
Age: embryonic day 14.5
Image: euxassay_011118_20
Specimen Label: euxassay_011118_20
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:3265722
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823808
Age: embryonic day 14.5
Image: euxassay_011118_21
Specimen Label: euxassay_011118_21
Detected: true
Specimen Num: 21
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