| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Cep55 is a centrosome protein that plays a role in mitotic exit and cytokinesis []. It is a regulator of the PI3K/AKT pathway and has been linked to cancers []. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
462
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jeffery J |
| Year: |
2016 |
| Journal: |
Oncogene |
| Title: |
Beyond cytokinesis: the emerging roles of CEP55 in tumorigenesis. |
| Volume: |
35 |
| Issue: |
6 |
| Pages: |
683-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Iwamori T |
| Year: |
2010 |
| Journal: |
Mol Cell Biol |
| Title: |
TEX14 interacts with CEP55 to block cell abscission. |
| Volume: |
30 |
| Issue: |
9 |
| Pages: |
2280-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sinha D |
| Year: |
2020 |
| Journal: |
Commun Biol |
| Title: |
Cep55 overexpression promotes genomic instability and tumorigenesis in mice. |
| Volume: |
3 |
| Issue: |
1 |
| Pages: |
593 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang YC |
| Year: |
2021 |
| Journal: |
J Cell Biol |
| Title: |
CEP55 promotes cilia disassembly through stabilizing Aurora A kinase. |
| Volume: |
220 |
| Issue: |
2 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rashidieh B |
| Year: |
2021 |
| Journal: |
PLoS Genet |
| Title: |
Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis. |
| Volume: |
17 |
| Issue: |
10 |
| Pages: |
e1009334 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chang YC |
| Year: |
2010 |
| Journal: |
J Cell Biochem |
| Title: |
Characterization of centrosomal proteins Cep55 and pericentrin in intercellular bridges of mouse testes. |
| Volume: |
109 |
| Issue: |
6 |
| Pages: |
1274-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tedeschi A |
| Year: |
2020 |
| Journal: |
Nat Commun |
| Title: |
Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
1746 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sinha D |
| Year: |
2018 |
| Journal: |
FASEB J |
| Title: |
Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling. |
| Volume: |
32 |
| Issue: |
9 |
| Pages: |
4984-4999 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Little JN |
| Year: |
2021 |
| Journal: |
J Neurosci |
| Title: |
Loss of Coiled-Coil Protein Cep55 Impairs Neural Stem Cell Abscission and Results in p53-Dependent Apoptosis in Developing Cortex. |
| Volume: |
41 |
| Issue: |
15 |
| Pages: |
3344-3365 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
189
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fabbro M |
| Year: |
2005 |
| Journal: |
Dev Cell |
| Title: |
Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis. |
| Volume: |
9 |
| Issue: |
4 |
| Pages: |
477-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
van der Horst A |
| Year: |
2009 |
| Journal: |
Cancer Res |
| Title: |
The peptidyl-prolyl isomerase Pin1 regulates cytokinesis through Cep55. |
| Volume: |
69 |
| Issue: |
16 |
| Pages: |
6651-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhou C |
| Year: |
2019 |
| Journal: |
J Cell Sci |
| Title: |
First meiotic anaphase requires Cep55-dependent inhibitory cyclin-dependent kinase 1 phosphorylation. |
| Volume: |
132 |
| Issue: |
18 |
|
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4428016 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-02-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7595806 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
Supplementary table 2 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-12-15 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797528 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4845890 |
| Age: |
postnatal day 15 |
|
| Note: |
Expression was detected in ring-shaped intercellular bridge structures in germ cells throughout the seminiferous tubules. Expression co-localized with Tex14. |
| Specimen Label: |
2B, 2D, 2E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-12-15 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797528 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4845890 |
| Age: |
postnatal week 6 |
|
| Note: |
Expression was detected in ring-shaped intercellular bridge structures in germ cells throughout the seminiferous tubules. Expression co-localized with Tex14. |
| Specimen Label: |
2G, 2I, 2J |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-12-15 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797528 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4845890 |
| Age: |
postnatal week 6 |
|
| Note: |
Expression was detected in ring-shaped intercellular bridge structures in germ cells throughout the seminiferous tubules. |
| Specimen Label: |
2L |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-12-15 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797528 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4845890 |
| Age: |
postnatal day 21 |
|
| Note: |
Expression was detected in intercellular bridge structures in germ cells. Expression co-localized with Tex14. |
| Specimen Label: |
10B, 10D |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-12-15 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797528 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4845890 |
| Age: |
postnatal day 21 |
|
| Note: |
Expression was detected in midbodies. |
| Specimen Label: |
10F, 10H |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-12-15 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797528 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4845890 |
| Age: |
postnatal day 21 |
|
| Note: |
Expression was detected in abscissed midbodies. |
| Specimen Label: |
10J, 10L |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845883 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-12-15 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:4845890 |
| Age: |
embryonic day 18.5 |
|
| Note: |
Expression colocalized with Tex14. |
| Specimen Label: |
3B, 3D, 3F, 3H |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuo TC |
| Year: |
2011 |
| Journal: |
Nat Cell Biol |
| Title: |
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. |
| Volume: |
13 |
| Issue: |
10 |
| Pages: |
1214-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI and IMPC |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen J |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
| Volume: |
100 |
| Issue: |
17 |
| Pages: |
9918-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Friedel RH |
| Year: |
2007 |
| Journal: |
Brief Funct Genomic Proteomic |
| Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
| Volume: |
6 |
| Issue: |
3 |
| Pages: |
180-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stryke D |
| Year: |
2003 |
| Journal: |
Nucleic Acids Res |
| Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
| Volume: |
31 |
| Issue: |
1 |
| Pages: |
278-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bedogni F |
| Year: |
2021 |
| Journal: |
Front Mol Neurosci |
| Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
| Volume: |
14 |
|
| Pages: |
686034 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
| Pages: |
1670-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helmholtz Zentrum Muenchen GmbH |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai J |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
| Issue: |
6821 |
| Pages: |
685-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
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|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
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•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This domain family is found in eukaryotes, and is approximately 40 amino acids in length. This domain is the active domain of CEP55. CEP55 is a protein involved in cytokinesis, specifically in abscission of the plasma membrane at the midbody. To perform this function, CEP55 complexes with ESCRT-I (by a Proline rich sequence in its TSG101 domain) and ALIX. This is the domain on CEP55 which binds to both TSG101 and ALIX. It also acts as a hinge between the N and C termini. This domain is called EABR. |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
461
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
430
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
451
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845887 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-12-15 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797528 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4845891 |
| Age: |
postnatal week 6 |
|
| Note: |
Expression was detected in ring-shaped intercellular bridge structures in germ cells throughout the seminiferous tubules. Expression co-localized with Cep55 |
| Specimen Label: |
2F, 2I, 2J |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Publication |
| First Author: |
de Cárcer G |
| Year: |
2018 |
| Journal: |
Nat Commun |
| Title: |
Plk1 overexpression induces chromosomal instability and suppresses tumor development. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
3012 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mondal G |
| Year: |
2012 |
| Journal: |
Mol Cell |
| Title: |
Tex14, a Plk1-regulated protein, is required for kinetochore-microtubule attachment and regulation of the spindle assembly checkpoint. |
| Volume: |
45 |
| Issue: |
5 |
| Pages: |
680-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Greenbaum MP |
| Year: |
2009 |
| Journal: |
Biol Reprod |
| Title: |
Mouse TEX14 is required for embryonic germ cell intercellular bridges but not female fertility. |
| Volume: |
80 |
| Issue: |
3 |
| Pages: |
449-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Greenbaum MP |
| Year: |
2006 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
TEX14 is essential for intercellular bridges and fertility in male mice. |
| Volume: |
103 |
| Issue: |
13 |
| Pages: |
4982-7 |
|
•
•
•
•
•
|