| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Charged multivesicular body protein 1a (CHMP1A, also known as chromatin-modifying protein 1A) is part of the ESCRT-III complex, which is required for endosome-mediated trafficking via multivesicular body (MVB) formation and sorting []. Besides being part of the ESCRT-III complex, it is also identified as a nuclear matrix protein affecting chromatin structure and cell-cycle progression []. In humans it acts as a tumour suppressor [, ]. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6726329 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270422 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:6726349 |
| Age: |
embryonic day 14.5 |
| Image: |
2E Chmp1a |
| Note: |
No expression in progenitors. |
| Specimen Label: |
2E Chmp1a |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6726329 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271122 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:6726349 |
| Age: |
embryonic day 14.5 |
| Image: |
2E Chmp1a |
| Note: |
Expression in postmitotic neurons in cerebral cortex. |
| Specimen Label: |
2E Chmp1a |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6726329 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3522327 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:6726349 |
| Age: |
postnatal day 0 |
| Image: |
2B Chmp1a |
| Note: |
Expression in Purkinje cell cytoplasm and dendrites; expression absent from nucleus. |
| Specimen Label: |
2B Chmp1a |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6726329 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3521627 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:6726349 |
| Age: |
postnatal day 0 |
| Image: |
2B Chmp1a |
|
| Specimen Label: |
2B Chmp1a |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6726329 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:6726349 |
| Age: |
embryonic day 14.5 |
| Image: |
2E Chmp1a |
| Note: |
No expression in progenitors. |
| Specimen Label: |
2E Chmp1a |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6726329 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3703827 |
| Pattern: |
Punctate |
| Stage: |
TS27 |
| Assay Id: |
MGI:6726349 |
| Age: |
postnatal day 0 |
| Image: |
S3A Chmp1a |
| Note: |
Punctate expression in epithelial cells of hindbrain choroid plexus. |
| Specimen Label: |
S3A Chmp1a |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stauffer DR |
| Year: |
2001 |
| Journal: |
J Cell Sci |
| Title: |
CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression. |
| Volume: |
114 |
| Issue: |
Pt 13 |
| Pages: |
2383-93 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6726329 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1778727 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:6726349 |
| Age: |
postnatal day 0 |
| Image: |
S3D Chmp1a null |
|
| Specimen Label: |
S3D Chmp1a null |
| Detected: |
false |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
196
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Coulter ME |
| Year: |
2018 |
| Journal: |
Cell Rep |
| Title: |
The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles. |
| Volume: |
24 |
| Issue: |
4 |
| Pages: |
973-986.e8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li J |
| Year: |
2008 |
| Journal: |
Cell Cycle |
| Title: |
Chmp1A functions as a novel tumor suppressor gene in human embryonic kidney and ductal pancreatic tumor cells. |
| Volume: |
7 |
| Issue: |
18 |
| Pages: |
2886-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Manohar S |
| Year: |
2011 |
| Journal: |
Cell Cycle |
| Title: |
Chromatin modifying protein 1A (Chmp1A) of the endosomal sorting complex required for transport (ESCRT)-III family activates ataxia telangiectasia mutated (ATM) for PanC-1 cell growth inhibition. |
| Volume: |
10 |
| Issue: |
15 |
| Pages: |
2529-39 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5447973 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284226 |
| Pattern: |
Regionally restricted |
| Stage: |
TS26 |
| Assay Id: |
MGI:6726346 |
| Age: |
embryonic day 18.5 |
| Image: |
1E Chmp1a null |
| Note: |
Authors report cortical plate is 13% thinner compared to controls. |
| Specimen Label: |
1E Chmp1a null |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5447971 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284226 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6726345 |
| Age: |
embryonic day 18.5 |
| Image: |
1E Ctip2 Chmp1a null |
| Note: |
Authors report cortical plate is 13% thinner than in controls. |
| Specimen Label: |
1E Ctip2 Chmp1a null |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5699394 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754926 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6726347 |
| Age: |
embryonic day 18.5 |
| Image: |
1E Chmp1a null |
| Note: |
Authors report striatum area is reduced by 25% compared to controls. |
| Specimen Label: |
1E Chmp1a null |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6726332 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271221 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:6726351 |
| Age: |
embryonic day 13.5 |
| Image: |
3C Chmp1a null |
| Note: |
Embryos have 26% fewer intermediate progenitors compared to controls. |
| Specimen Label: |
3C Chmp1a null |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6725841 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-07-27 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1778727 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:6726343 |
| Age: |
postnatal day 0 |
| Image: |
3E Chmp1a null |
| Note: |
Expression reduced in cerebellum. |
| Specimen Label: |
3E Chmp1a null |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5827948 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754420 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:6726356 |
| Age: |
embryonic day 12.5 |
| Image: |
S4C Chmp1a null |
| Note: |
No detectable increase in apoptosis compared to controls. |
| Specimen Label: |
S4C Chmp1a null |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2681585 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754422 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:6726358 |
| Age: |
embryonic day 14.5 |
| Image: |
S4E aPKC Chmp1a null |
| Note: |
No detectable defect in cortical ventricular surface. |
| Specimen Label: |
S4E aPKC Chmp1a null |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2681585 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754422 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:6726359 |
| Age: |
embryonic day 14.5 |
| Image: |
S4E aPKC Chmp1a null |
| Note: |
No detectable defect in cortical ventricular surface. |
| Specimen Label: |
S4E aPKC Chmp1a null |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6726336 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754422 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:6726360 |
| Age: |
embryonic day 14.5 |
| Image: |
S5A Chmp1a null |
| Note: |
No detectable difference in faction of mitotic cells in cytokinesis. |
| Specimen Label: |
S5A Chmp1a null |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6726328 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3522327 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:6726348 |
| Age: |
postnatal day 0 |
| Image: |
S4A Chmp1a null |
| Note: |
Purkinje cell layer is intact and unchanged compared to controls. |
| Specimen Label: |
S4A Chmp1a null |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guan Y |
| Year: |
2021 |
| Journal: |
Nat Commun |
| Title: |
A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
5078 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7855121 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2025-01-22 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1689423 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:7855199 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
Female |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7855121 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2025-01-22 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689423 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:7855199 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
Male |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7529137 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3642217 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7529139 |
| Age: |
embryonic day 10.5 |
| Image: |
4C |
| Note: |
Expression was enriched in the cranial neural crest cells (CCNC) of the trigeminal stream. Co-localization was observed with the CCNC marker, Sox10. |
| Specimen Label: |
4C |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6726329 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1778727 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:6726349 |
| Age: |
postnatal day 0 |
| Image: |
S3D Control |
|
| Specimen Label: |
S3D Control |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3522328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6726344 |
| Age: |
postnatal day 4 |
| Image: |
2A |
|
| Specimen Label: |
2A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-07-27 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3521628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6726344 |
| Age: |
postnatal day 4 |
| Image: |
2A |
|
| Specimen Label: |
2A |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-07-27 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3274228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6726344 |
| Age: |
postnatal day 4 |
| Image: |
2A |
|
| Specimen Label: |
2A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2449010 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-07-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754422 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:6726357 |
| Age: |
embryonic day 14.5 |
| Image: |
S4E Beta Catenin Chmp1a null |
| Note: |
No detectable defect in cortical ventricular surface. |
| Specimen Label: |
S4E Beta Catenin Chmp1a null |
| Detected: |
true |
| Specimen Num: |
2 |
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