| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Cytochrome P450 1B1 (CYP1B1) is an enzyme that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, retinoid and xenobiotics [, ]. It has been linked to primary congenital glaucoma []and cancers [, ]. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Choudhary D |
| Year: |
2004 |
| Journal: |
Drug Metab Dispos |
| Title: |
Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1. |
| Volume: |
32 |
| Issue: |
8 |
| Pages: |
840-7 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Madeen EP |
| Year: |
2017 |
| Journal: |
Mol Carcinog |
| Title: |
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice. |
| Volume: |
56 |
| Issue: |
1 |
| Pages: |
163-171 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li F |
| Year: |
2014 |
| Journal: |
J Proteome Res |
| Title: |
Lipidomics reveals a link between CYP1B1 and SCD1 in promoting obesity. |
| Volume: |
13 |
| Issue: |
5 |
| Pages: |
2679-87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishida CR |
| Year: |
2013 |
| Journal: |
Mol Pharmacol |
| Title: |
Specificity determinants of CYP1B1 estradiol hydroxylation. |
| Volume: |
84 |
| Issue: |
3 |
| Pages: |
451-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mitsui Y |
| Year: |
2015 |
| Journal: |
BMC Cancer |
| Title: |
CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma. |
| Volume: |
15 |
|
| Pages: |
942 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dong H |
| Year: |
2013 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Mitochondrial targeting of mouse NQO1 and CYP1B1 proteins. |
| Volume: |
435 |
| Issue: |
4 |
| Pages: |
727-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Palenski TL |
| Year: |
2013 |
| Journal: |
Am J Physiol Cell Physiol |
| Title: |
Cyp1B1 expression promotes angiogenesis by suppressing NF-κB activity. |
| Volume: |
305 |
| Issue: |
11 |
| Pages: |
C1170-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Buters JT |
| Year: |
1999 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas. |
| Volume: |
96 |
| Issue: |
5 |
| Pages: |
1977-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Choudhary D |
| Year: |
2007 |
| Journal: |
Drug Metab Dispos |
| Title: |
Cyp1b1 protein in the mouse eye during development: an immunohistochemical study. |
| Volume: |
35 |
| Issue: |
6 |
| Pages: |
987-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alexander DL |
| Year: |
1997 |
| Journal: |
Cancer Res |
| Title: |
Ah receptor regulation of CYP1B1 expression in primary mouse embryo-derived cells. |
| Volume: |
57 |
| Issue: |
20 |
| Pages: |
4498-506 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tang Y |
| Year: |
2009 |
| Journal: |
Blood |
| Title: |
CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression. |
| Volume: |
113 |
| Issue: |
3 |
| Pages: |
744-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Palenski TL |
| Year: |
2013 |
| Journal: |
Lab Invest |
| Title: |
Lack of Cyp1b1 promotes the proliferative and migratory phenotype of perivascular supporting cells. |
| Volume: |
93 |
| Issue: |
6 |
| Pages: |
646-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Falero-Perez J |
| Year: |
2018 |
| Journal: |
PLoS One |
| Title: |
Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells. |
| Volume: |
13 |
| Issue: |
10 |
| Pages: |
e0206756 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dempsie Y |
| Year: |
2013 |
| Journal: |
Cardiovasc Res |
| Title: |
Dexfenfluramine and the oestrogen-metabolizing enzyme CYP1B1 in the development of pulmonary arterial hypertension. |
| Volume: |
99 |
| Issue: |
1 |
| Pages: |
24-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Falero-Perez J |
| Year: |
2019 |
| Journal: |
Trends Dev Biol |
| Title: |
Targeted deletion of Cyp1b1 in pericytes results in attenuation of retinal neovascularization and trabecular meshwork dysgenesis. |
| Volume: |
12 |
|
| Pages: |
1-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ye G |
| Year: |
2023 |
| Journal: |
Exp Mol Med |
| Title: |
ALKBH5 facilitates CYP1B1 mRNA degradation via m6A demethylation to alleviate MSC senescence and osteoarthritis progression. |
| Volume: |
55 |
| Issue: |
8 |
| Pages: |
1743-1756 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao Y |
| Year: |
2013 |
| Journal: |
Mol Cell Biol |
| Title: |
Cyp1b1 mediates periostin regulation of trabecular meshwork development by suppression of oxidative stress. |
| Volume: |
33 |
| Issue: |
21 |
| Pages: |
4225-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bushkofsky JR |
| Year: |
2016 |
| Journal: |
Arch Biochem Biophys |
| Title: |
Cyp1b1 affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4α and PPARα. |
| Volume: |
597 |
|
| Pages: |
30-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zheng W |
| Year: |
2013 |
| Journal: |
Arch Biochem Biophys |
| Title: |
Stimulation of mouse Cyp1b1 during adipogenesis: characterization of promoter activation by the transcription factor Pax6. |
| Volume: |
532 |
| Issue: |
1 |
| Pages: |
1-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maguire M |
| Year: |
2017 |
| Journal: |
Mol Cell Endocrinol |
| Title: |
Cyp1b1 deletion and retinol deficiency coordinately suppress mouse liver lipogenic genes and hepcidin expression during post-natal development. |
| Volume: |
454 |
|
| Pages: |
50-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kerzee JK |
| Year: |
2001 |
| Journal: |
Circ Res |
| Title: |
Constitutive and inducible expression of Cyp1a1 and Cyp1b1 in vascular smooth muscle cells: role of the Ahr bHLH/PAS transcription factor. |
| Volume: |
89 |
| Issue: |
7 |
| Pages: |
573-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maguire M |
| Year: |
2020 |
| Journal: |
PLoS One |
| Title: |
Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development. |
| Volume: |
15 |
| Issue: |
2 |
| Pages: |
e0228436 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tang Y |
| Year: |
2010 |
| Journal: |
Am J Physiol Cell Physiol |
| Title: |
CYP1B1 and endothelial nitric oxide synthase combine to sustain proangiogenic functions of endothelial cells under hyperoxic stress. |
| Volume: |
298 |
| Issue: |
3 |
| Pages: |
C665-78 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Smerdová L |
| Year: |
2014 |
| Journal: |
Carcinogenesis |
| Title: |
Upregulation of CYP1B1 expression by inflammatory cytokines is mediated by the p38 MAP kinase signal transduction pathway. |
| Volume: |
35 |
| Issue: |
11 |
| Pages: |
2534-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dragin N |
| Year: |
2006 |
| Journal: |
J Biol Chem |
| Title: |
For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential. |
| Volume: |
281 |
| Issue: |
27 |
| Pages: |
18591-600 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
543
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
487
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
289
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
307
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
324
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
543
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shimada T |
| Year: |
1999 |
| Journal: |
Carcinogenesis |
| Title: |
Catalytic properties of polymorphic human cytochrome P450 1B1 variants. |
| Volume: |
20 |
| Issue: |
8 |
| Pages: |
1607-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao Y |
| Year: |
2015 |
| Journal: |
J Ophthalmic Vis Res |
| Title: |
Cytochrome P450 1B1 and Primary Congenital Glaucoma. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
60-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wei YK |
| Year: |
2015 |
| Journal: |
J Environ Pathol Toxicol Oncol |
| Title: |
Genistein Induces Cytochrome P450 1B1 Gene Expression and Cell Proliferation in Human Breast Cancer MCF-7 Cells. |
| Volume: |
34 |
| Issue: |
2 |
| Pages: |
153-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Uno S |
| Year: |
2006 |
| Journal: |
Mol Pharmacol |
| Title: |
Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate. |
| Volume: |
69 |
| Issue: |
4 |
| Pages: |
1103-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Larsen MC |
| Year: |
2023 |
| Journal: |
Int J Mol Sci |
| Title: |
AhR and CYP1B1 Control Oxygen Effects on Bone Marrow Progenitor Cells: The Enrichment of Multiple Olfactory Receptors as Potential Microbiome Sensors. |
| Volume: |
24 |
| Issue: |
23 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Savas U |
| Year: |
1997 |
| Journal: |
Arch Biochem Biophys |
| Title: |
Biological oxidations and P450 reactions. Recombinant mouse CYP1B1 expressed in Escherichia coli exhibits selective binding by polycyclic hydrocarbons and metabolism which parallels C3H10T1/2 cell microsomes, but differs from human recombinant CYP1B1. |
| Volume: |
347 |
| Issue: |
2 |
| Pages: |
181-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Siddens LK |
| Year: |
2015 |
| Journal: |
Toxicol Appl Pharmacol |
| Title: |
Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse. |
| Volume: |
287 |
| Issue: |
2 |
| Pages: |
149-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shen Z |
| Year: |
1994 |
| Journal: |
DNA Cell Biol |
| Title: |
cDNA cloning, sequence analysis, and induction by aryl hydrocarbons of a murine cytochrome P450 gene, Cyp1b1. |
| Volume: |
13 |
| Issue: |
7 |
| Pages: |
763-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sarfarazi M |
| Year: |
2003 |
| Journal: |
Ophthalmol Clin North Am |
| Title: |
Genetics and biochemistry of primary congenital glaucoma. |
| Volume: |
16 |
| Issue: |
4 |
| Pages: |
543-54, vi |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Libby RT |
| Year: |
2003 |
| Journal: |
Science |
| Title: |
Modification of ocular defects in mouse developmental glaucoma models by tyrosinase. |
| Volume: |
299 |
| Issue: |
5612 |
| Pages: |
1578-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lewis JM |
| Year: |
2015 |
| Journal: |
J Invest Dermatol |
| Title: |
Mechanisms of chemical cooperative carcinogenesis by epidermal Langerhans cells. |
| Volume: |
135 |
| Issue: |
5 |
| Pages: |
1405-1414 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Larsen MC |
| Year: |
2015 |
| Journal: |
Arch Biochem Biophys |
| Title: |
Cytochrome P450 1B1: An unexpected modulator of liver fatty acid homeostasis. |
| Volume: |
571 |
|
| Pages: |
21-39 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Falero-Perez J |
| Year: |
2019 |
| Journal: |
Am J Physiol Cell Physiol |
| Title: |
Cyp1b1-deficient retinal astrocytes are more proliferative and migratory and are protected from oxidative stress and inflammation. |
| Volume: |
316 |
| Issue: |
6 |
| Pages: |
C767-C781 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Grimm SL |
| Year: |
2023 |
| Journal: |
Redox Biol |
| Title: |
Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation. |
| Volume: |
64 |
|
| Pages: |
102790 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Heidel SM |
| Year: |
2000 |
| Journal: |
Cancer Res |
| Title: |
Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene. |
| Volume: |
60 |
| Issue: |
13 |
| Pages: |
3454-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ward JM |
| Year: |
2004 |
| Journal: |
Toxicol Pathol |
| Title: |
Progressive glomerulonephritis and histiocytic sarcoma associated with macrophage functional defects in CYP1B1-deficient mice. |
| Volume: |
32 |
| Issue: |
6 |
| Pages: |
710-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Peng J |
| Year: |
2013 |
| Journal: |
Carcinogenesis |
| Title: |
Estrogen metabolism within the lung and its modulation by tobacco smoke. |
| Volume: |
34 |
| Issue: |
4 |
| Pages: |
909-15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McLellan RA |
| Year: |
2000 |
| Journal: |
Arch Biochem Biophys |
| Title: |
Characterization and functional analysis of two common human cytochrome P450 1B1 variants. |
| Volume: |
378 |
| Issue: |
1 |
| Pages: |
175-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jennings BL |
| Year: |
2012 |
| Journal: |
Hypertension |
| Title: |
Cytochrome P450 1B1 contributes to renal dysfunction and damage caused by angiotensin II in mice. |
| Volume: |
59 |
| Issue: |
2 |
| Pages: |
348-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gálvez-Peralta M |
| Year: |
2013 |
| Journal: |
Int J Cancer |
| Title: |
Oral benzo[a]pyrene in Cyp1a1/1b1(-/-) double-knockout mice: Microarray analysis during squamous cell carcinoma formation in preputial gland duct. |
| Volume: |
132 |
| Issue: |
9 |
| Pages: |
2065-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu M |
| Year: |
2004 |
| Journal: |
Toxicol Appl Pharmacol |
| Title: |
Determination of murine fetal Cyp1a1 and 1b1 expression by real-time fluorescence reverse transcription-polymerase chain reaction. |
| Volume: |
201 |
| Issue: |
3 |
| Pages: |
295-302 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Savas U |
| Year: |
1994 |
| Journal: |
J Biol Chem |
| Title: |
Mouse cytochrome P-450EF, representative of a new 1B subfamily of cytochrome P-450s. Cloning, sequence determination, and tissue expression. |
| Volume: |
269 |
| Issue: |
21 |
| Pages: |
14905-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Amirmokhtari N |
| Year: |
2021 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Absence of Cytochrome P450-1b1 Increases Susceptibility of Pressure-Induced Axonopathy in the Murine Retinal Projection. |
| Volume: |
9 |
|
| Pages: |
636321 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dinu D |
| Year: |
2016 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Mechanistic role of cytochrome P450 (CYP)1B1 in oxygen-mediated toxicity in pulmonary cells: A novel target for prevention of hyperoxic lung injury. |
| Volume: |
476 |
| Issue: |
4 |
| Pages: |
346-351 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gao J |
| Year: |
2005 |
| Journal: |
Toxicol Sci |
| Title: |
Cytochrome P450 1B1 is required for 7,12-dimethylbenz(a)-anthracene (DMBA) induced spleen cell immunotoxicity. |
| Volume: |
86 |
| Issue: |
1 |
| Pages: |
68-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
White K |
| Year: |
2012 |
| Journal: |
Circulation |
| Title: |
Activity of the estrogen-metabolizing enzyme cytochrome P450 1B1 influences the development of pulmonary arterial hypertension. |
| Volume: |
126 |
| Issue: |
9 |
| Pages: |
1087-98 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bhattacharyya KK |
| Year: |
1995 |
| Journal: |
J Biol Chem |
| Title: |
Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYP1B1. Demonstration of a unique tissue-specific pattern of hormonal and aryl hydrocarbon receptor-linked regulation. |
| Volume: |
270 |
| Issue: |
19 |
| Pages: |
11595-602 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stoilov I |
| Year: |
2004 |
| Journal: |
Mol Vis |
| Title: |
Expression of cytochrome P4501b1 (Cyp1b1) during early murine development. |
| Volume: |
10 |
|
| Pages: |
629-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mukherjee K |
| Year: |
2018 |
| Journal: |
J Am Heart Assoc |
| Title: |
Cytochrome P450 1B1 Is Critical for Neointimal Growth in Wire-Injured Carotid Artery of Male Mice. |
| Volume: |
7 |
| Issue: |
18 |
| Pages: |
e010065 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mair KM |
| Year: |
2019 |
| Journal: |
Eur Respir J |
| Title: |
Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension. |
| Volume: |
53 |
| Issue: |
6 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Thirunavukkarasu S |
| Year: |
2016 |
| Journal: |
Am J Pathol |
| Title: |
Cytochrome P450 1B1 Contributes to the Development of Angiotensin II-Induced Aortic Aneurysm in Male Apoe(-/-) Mice. |
| Volume: |
186 |
| Issue: |
8 |
| Pages: |
2204-2219 |
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•
•
•
•
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| Publication |
| First Author: |
Song CY |
| Year: |
2016 |
| Journal: |
Hypertension |
| Title: |
Cytochrome P450 1B1 Contributes to the Development of Atherosclerosis and Hypertension in Apolipoprotein E-Deficient Mice. |
| Volume: |
67 |
| Issue: |
1 |
| Pages: |
206-13 |
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•
•
•
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| Publication |
| First Author: |
Pingili AK |
| Year: |
2016 |
| Journal: |
Hypertension |
| Title: |
6β-Hydroxytestosterone, a Cytochrome P450 1B1-Testosterone-Metabolite, Mediates Angiotensin II-Induced Renal Dysfunction in Male Mice. |
| Volume: |
67 |
| Issue: |
5 |
| Pages: |
916-26 |
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| First Author: |
Choudhary D |
| Year: |
2005 |
| Journal: |
Arch Biochem Biophys |
| Title: |
Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues. |
| Volume: |
436 |
| Issue: |
1 |
| Pages: |
50-61 |
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| First Author: |
Pingili AK |
| Year: |
2020 |
| Journal: |
Biol Sex Differ |
| Title: |
6β-Hydroxytestosterone, a metabolite of testosterone generated by CYP1B1, contributes to vascular changes in angiotensin II-induced hypertension in male mice. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
4 |
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| First Author: |
Hwang DY |
| Year: |
2001 |
| Journal: |
Arch Biochem Biophys |
| Title: |
Xenobiotic response in humanized double transgenic mice expressing tetracycline-controlled transactivator and human CYP1B1. |
| Volume: |
395 |
| Issue: |
1 |
| Pages: |
32-40 |
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| First Author: |
Stading R |
| Year: |
2024 |
| Journal: |
Free Radic Biol Med |
| Title: |
Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury: Role of cytochrome P450 (CYP)1A1, 1A2, and 1B1. |
| Volume: |
211 |
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| Pages: |
35-46 |
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| First Author: |
Bansal S |
| Year: |
2014 |
| Journal: |
J Biol Chem |
| Title: |
Mitochondrial targeting of cytochrome P450 (CYP) 1B1 and its role in polycyclic aromatic hydrocarbon-induced mitochondrial dysfunction. |
| Volume: |
289 |
| Issue: |
14 |
| Pages: |
9936-51 |
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Uno S |
| Year: |
2008 |
| Journal: |
Free Radic Biol Med |
| Title: |
Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract. |
| Volume: |
44 |
| Issue: |
4 |
| Pages: |
570-83 |
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| First Author: |
Iqbal J |
| Year: |
2013 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes. |
| Volume: |
110 |
| Issue: |
27 |
| Pages: |
11115-20 |
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Gonzalez FJ |
| Year: |
1999 |
| Journal: |
Cancer Lett |
| Title: |
Role of gene knockout mice in understanding the mechanisms of chemical toxicity and carcinogenesis. |
| Volume: |
143 |
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2 |
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199-204 |
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MacPherson L |
| Year: |
2013 |
| Journal: |
Nucleic Acids Res |
| Title: |
2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation. |
| Volume: |
41 |
| Issue: |
3 |
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1604-21 |
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Borland MG |
| Year: |
2014 |
| Journal: |
Carcinogenesis |
| Title: |
Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes. |
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35 |
| Issue: |
7 |
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1602-12 |
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Alessandrini F |
| Year: |
2022 |
| Journal: |
Front Immunol |
| Title: |
Lung Epithelial CYP1 Activity Regulates Aryl Hydrocarbon Receptor Dependent Allergic Airway Inflammation. |
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13 |
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901194 |
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| First Author: |
Shertzer HG |
| Year: |
2007 |
| Journal: |
Carcinogenesis |
| Title: |
7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes. |
| Volume: |
28 |
| Issue: |
6 |
| Pages: |
1371-8 |
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| First Author: |
Shin S |
| Year: |
2007 |
| Journal: |
Mol Cell Biol |
| Title: |
NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis. |
| Volume: |
27 |
| Issue: |
20 |
| Pages: |
7188-97 |
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Nebert DW |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer. |
| Volume: |
279 |
| Issue: |
23 |
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23847-50 |
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| First Author: |
Dragin N |
| Year: |
2008 |
| Journal: |
Mol Pharmacol |
| Title: |
Phenotype of the Cyp1a1/1a2/1b1-/- triple-knockout mouse. |
| Volume: |
73 |
| Issue: |
6 |
| Pages: |
1844-56 |
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•
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| First Author: |
Behesti H |
| Year: |
2009 |
| Journal: |
Dev Biol |
| Title: |
Loss of Tbx2 delays optic vesicle invagination leading to small optic cups. |
| Volume: |
333 |
| Issue: |
2 |
| Pages: |
360-72 |
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| Publication |
| First Author: |
Choudhary D |
| Year: |
2003 |
| Journal: |
Arch Biochem Biophys |
| Title: |
Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues. |
| Volume: |
414 |
| Issue: |
1 |
| Pages: |
91-100 |
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•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|