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Search results 1 to 100 out of 805 for Ddit3

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
1649 | DDIT3
Type: gene
Organism: human
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Gene
733816 | ddit3
Type: gene
Organism: frog, western clawed
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Gene
29467 | Ddit3
Type: gene
Organism: rat
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Gene
607439 | DDIT3
Type: gene
Organism: dog, domestic
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Gene
452017 | DDIT3
Type: gene
Organism: chimpanzee
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Gene
777788 | DDIT3
Type: gene
Organism: cattle
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Gene
561924 | ddit3
Type: gene
Organism: zebrafish
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Gene
714901 | DDIT3
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:109247 | Ddit3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
26051941 | J:336341
First Author: Pina C
Year: 2015
Journal: Cell Rep
Title: Single-Cell Network Analysis Identifies DDIT3 as a Nodal Lineage Regulator in Hematopoiesis.
Volume: 11
Issue: 10
Pages: 1503-10
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GXD Expression
GXD Expression
     
Probe: MGI:6171020
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190107
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Ddit3
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6171020
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190107
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Ddit3
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6171020
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190107
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Ddit3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6171020
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190107
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Ddit3
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6171020
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190107
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Ddit3
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6171020
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190107
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Ddit3
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6171020
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190107
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Ddit3
Detected: true
Specimen Num: 7
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Protein
A0A2R8VHR8
Organism: Mus musculus/domesticus
Length: 34  
Fragment?: false
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Publication
35381294 | J:328976
First Author: Yu X
Year: 2022
Journal: Biochim Biophys Acta Mol Cell Res
Title: DDIT3/CHOP mediates the inhibitory effect of ER stress on chondrocyte differentiation by AMPKα-SIRT1 pathway.
Volume: 1869
Issue: 8
Pages: 119265
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Publication
34087318 | J:328965
First Author: Yang C
Year: 2021
Journal: Biochim Biophys Acta Mol Cell Res
Title: DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway.
Volume: 1868
Issue: 9
Pages: 119074
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Publication
33691741 | J:328973
First Author: Li H
Year: 2021
Journal: Mol Neurodegener
Title: High dose expression of heme oxigenase-1 induces retinal degeneration through ER stress-related DDIT3.
Volume: 16
Issue: 1
Pages: 16
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Publication
36167070 | J:349562
First Author: Shayya HJ
Year: 2022
Journal: Cell
Title: ER stress transforms random olfactory receptor choice into axon targeting precision.
Volume: 185
Issue: 21
Pages: 3896-3912.e22
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Publication
27039902 | J:235869
First Author: Bensellam M
Year: 2016
Journal: Diabetologia
Title: Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells.
Volume: 59
Issue: 7
Pages: 1492-1502
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Gene
129135244 | LOC129135244
Type: gene
Organism: chimpanzee
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Gene
132345297 | LOC132345297
Type: gene
Organism: cattle
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Gene
134479709 | LOC134479709
Type: gene
Organism: rat
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Publication
30081710 | J:306954
First Author: Zecchini S
Year: 2019
Journal: Autophagy
Title: Autophagy controls neonatal myogenesis by regulating the GH-IGF1 system through a NFE2L2- and DDIT3-mediated mechanism.
Volume: 15
Issue: 1
Pages: 58-77
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Protein Coding Gene
MGP_CAROLIEiJ_G0015890 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017816 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017791 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017754 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017755 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017579 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_109247 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018210 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017139 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017548 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017654 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017649 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017728 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017677 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018250 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016924 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017200 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031195 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016716 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1547942 | J:38292
First Author: Ron D
Year: 1992
Journal: Genes Dev
Title: CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.
Volume: 6
Issue: 3
Pages: 439-53
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Publication
10346810 | J:55423
First Author: Kaufman RJ
Year: 1999
Journal: Genes Dev
Title: Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls.
Volume: 13
Issue: 10
Pages: 1211-33
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Publication
26900721 | J:321105
First Author: Gurlo T
Year: 2016
Journal: Mol Endocrinol
Title: CHOP Contributes to, But Is Not the Only Mediator of, IAPP Induced β-Cell Apoptosis.
Volume: 30
Issue: 4
Pages: 446-54
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Publication
11526215 | J:76277
First Author: Oyadomari S
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway.
Volume: 98
Issue: 19
Pages: 10845-50
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Publication
20625112 | J:178591
First Author: Fu HY
Year: 2010
Journal: Circulation
Title: Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload.
Volume: 122
Issue: 4
Pages: 361-9
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Publication
28228268 | J:250941
First Author: Suzuki T
Year: 2017
Journal: Cell Rep
Title: ER Stress Protein CHOP Mediates Insulin Resistance by Modulating Adipose Tissue Macrophage Polarity.
Volume: 18
Issue: 8
Pages: 2045-2057
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Publication
23374428 | J:212450
First Author: Yamabe S
Year: 2013
Journal: FEBS J
Title: Intracellular accumulation of advanced glycation end products induces apoptosis via endoplasmic reticulum stress in chondrocytes.
Volume: 280
Issue: 7
Pages: 1617-29
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Publication
14752508 | J:115471
First Author: Tajiri S
Year: 2004
Journal: Cell Death Differ
Title: Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP.
Volume: 11
Issue: 4
Pages: 403-15
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Publication
22237685 | J:182554
First Author: Maris M
Year: 2012
Journal: Diabetologia
Title: Deletion of C/EBP homologous protein (Chop) in C57Bl/6 mice dissociates obesity from insulin resistance.
Volume: 55
Issue: 4
Pages: 1167-78
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Publication
16880521 | J:111406
First Author: Shirakawa K
Year: 2006
Journal: Mol Cell Biol
Title: CCAAT/enhancer-binding protein homologous protein (CHOP) regulates osteoblast differentiation.
Volume: 26
Issue: 16
Pages: 6105-16
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Publication
19359519 | J:147964
First Author: Namba T
Year: 2009
Journal: Am J Pathol
Title: Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis.
Volume: 174
Issue: 5
Pages: 1786-98
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Publication
21330607 | J:191489
First Author: Miyazaki Y
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: C/EBP homologous protein deficiency attenuates myocardial reperfusion injury by inhibiting myocardial apoptosis and inflammation.
Volume: 31
Issue: 5
Pages: 1124-32
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Publication
18166146 | J:131057
First Author: Suyama K
Year: 2008
Journal: Biochem Biophys Res Commun
Title: C/EBP homologous protein is crucial for the acceleration of experimental pancreatitis.
Volume: 367
Issue: 1
Pages: 176-82
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Publication
34752818 | J:331183
 
First Author: Sato K
Year: 2021
Journal: Exp Eye Res
Title: CHOP deletion and anti-neuroinflammation treatment with hesperidin synergistically attenuate NMDA retinal injury in mice.
Volume: 213
Pages: 108826
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Publication
26005208 | J:317946
 
First Author: Tanaka Y
Year: 2015
Journal: Pharmacol Res
Title: The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice.
Volume: 99
Pages: 52-62
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Publication
16716308 | J:109623
First Author: Tajiri S
Year: 2006
Journal: FEBS Lett
Title: CHOP is involved in neuronal apoptosis induced by neurotrophic factor deprivation.
Volume: 580
Issue: 14
Pages: 3462-8
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Publication
19733664 | J:154934
First Author: Ito Y
Year: 2009
Journal: Neurobiol Dis
Title: Involvement of CHOP, an ER-stress apoptotic mediator, in both human sporadic ALS and ALS model mice.
Volume: 36
Issue: 3
Pages: 470-6
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Publication
24367269 | J:207510
First Author: DeZwaan-McCabe D
Year: 2013
Journal: PLoS Genet
Title: The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis.
Volume: 9
Issue: 12
Pages: e1003937
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Publication
29386258 | J:258145
First Author: Hood KN
Year: 2018
Journal: J Neurosci
Title: Endoplasmic Reticulum Stress Contributes to the Loss of Newborn Hippocampal Neurons after Traumatic Brain Injury.
Volume: 38
Issue: 9
Pages: 2372-2384
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Publication
25895586 | J:283212
First Author: Jo F
Year: 2015
Journal: Hypertension
Title: Brain endoplasmic reticulum stress mechanistically distinguishes the saline-intake and hypertensive response to deoxycorticosterone acetate-salt.
Volume: 65
Issue: 6
Pages: 1341-8
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Publication
24776803 | J:212934
First Author: van Galen P
Year: 2014
Journal: Nature
Title: The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress.
Volume: 510
Issue: 7504
Pages: 268-72
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Publication
23361066 | J:329090
First Author: Engel T
Year: 2013
Journal: Brain
Title: CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures.
Volume: 136
Issue: Pt 2
Pages: 577-92
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Publication
23720735 | J:199651
First Author: Malhi H
Year: 2013
Journal: J Biol Chem
Title: C/EBP homologous protein-induced macrophage apoptosis protects mice from steatohepatitis.
Volume: 288
Issue: 26
Pages: 18624-42
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Publication
23364451 | J:208557
First Author: Lupachyk S
Year: 2013
Journal: Diabetes
Title: Endoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathy.
Volume: 62
Issue: 3
Pages: 944-52
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Publication
16220546 | J:268071
First Author: Pereira RC
Year: 2006
Journal: J Cell Biochem
Title: C/EBP homologous protein is necessary for normal osteoblastic function.
Volume: 97
Issue: 3
Pages: 633-40
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Publication
16135078 | J:219626
First Author: Silva RM
Year: 2005
Journal: J Neurochem
Title: CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism.
Volume: 95
Issue: 4
Pages: 974-86
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Publication
24194321 | J:233238
First Author: Posey KL
Year: 2014
Journal: J Bone Miner Res
Title: Chondrocyte-specific pathology during skeletal growth and therapeutics in a murine model of pseudoachondroplasia.
Volume: 29
Issue: 5
Pages: 1258-68
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Publication
16936275 | J:112354
First Author: Clase AC
Year: 2006
Journal: Am J Pathol
Title: Oligodendrocytes are a major target of the toxicity of spongiogenic murine retroviruses.
Volume: 169
Issue: 3
Pages: 1026-38
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Publication
20044139 | J:158399
First Author: Masciarelli S
Year: 2010
Journal: Mol Immunol
Title: CHOP-independent apoptosis and pathway-selective induction of the UPR in developing plasma cells.
Volume: 47
Issue: 6
Pages: 1356-65
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Publication
23749468 | J:202871
First Author: Mueller K
Year: 2013
Journal: J Pathol
Title: CHOP-mediated hepcidin suppression modulates hepatic iron load.
Volume: 231
Issue: 4
Pages: 532-42
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Publication
30835896 | J:293977
First Author: Wu CT
Year: 2019
Journal: J Orthop Res
Title: Gender difference of CCAAT/enhancer binding protein homologous protein deficiency in susceptibility to osteopenia.
Volume: 37
Issue: 4
Pages: 942-947
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Publication
28267207 | J:249802
First Author: Valderrama C
Year: 2017
Journal: Eur J Immunol
Title: Listeria monocytogenes induces an interferon-enhanced activation of the integrated stress response that is detrimental for resolution of infection in mice.
Volume: 47
Issue: 5
Pages: 830-840
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Publication
24416259 | J:212207
First Author: Carlisle RE
Year: 2014
Journal: PLoS One
Title: 4-Phenylbutyrate inhibits tunicamycin-induced acute kidney injury via CHOP/GADD153 repression.
Volume: 9
Issue: 1
Pages: e84663
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Publication
20159858 | J:162886
First Author: Pfaffenbach KT
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death.
Volume: 298
Issue: 5
Pages: E1027-35
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Publication
24662293 | J:214136
First Author: Grant R
Year: 2014
Journal: J Biol Chem
Title: Inactivation of C/ebp homologous protein-driven immune-metabolic interactions exacerbate obesity and adipose tissue leukocytosis.
Volume: 289
Issue: 20
Pages: 14045-55
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Publication
26942460 | J:313154
First Author: Liu SH
Year: 2016
Journal: Oncotarget
Title: C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease.
Volume: 7
Issue: 16
Pages: 21900-12
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Publication
23235477 | J:193184
First Author: Esposito V
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: CHOP deficiency results in elevated lipopolysaccharide-induced inflammation and kidney injury.
Volume: 304
Issue: 4
Pages: F440-50
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Publication
30135303 | J:328975
 
First Author: Burman A
Year: 2018
Journal: JCI Insight
Title: Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein.
Volume: 3
Issue: 16
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Publication
26071644 | J:233924
First Author: Noh MR
Year: 2015
Journal: Biochim Biophys Acta
Title: C/EBP homologous protein (CHOP) gene deficiency attenuates renal ischemia/reperfusion injury in mice.
Volume: 1852
Issue: 9
Pages: 1895-901
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Publication
21964030 | J:179506
First Author: Deslauriers AM
Year: 2011
Journal: J Immunol
Title: Neuroinflammation and endoplasmic reticulum stress are coregulated by crocin to prevent demyelination and neurodegeneration.
Volume: 187
Issue: 9
Pages: 4788-99
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Publication
28953979 | J:250446
First Author: English BC
Year: 2017
Journal: PLoS Pathog
Title: The transcription factor CHOP, an effector of the integrated stress response, is required for host sensitivity to the fungal intracellular pathogen Histoplasma capsulatum.
Volume: 13
Issue: 9
Pages: e1006589
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Publication
26111448 | J:228667
First Author: Luo G
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Ablation of C/EBP homologous protein increases the acute phase mortality and doesn't attenuate cardiac remodeling in mice with myocardial infarction.
Volume: 464
Issue: 1
Pages: 201-7
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Publication
26027784 | J:225750
 
First Author: Nam DH
Year: 2015
Journal: J Mol Cell Cardiol
Title: CHOP deficiency prevents methylglyoxal-induced myocyte apoptosis and cardiac dysfunction.
Volume: 85
Pages: 168-77
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Publication
35727920 | J:333191
First Author: Steinberger AE
Year: 2022
Journal: Am J Physiol Gastrointest Liver Physiol
Title: A novel maladaptive unfolded protein response as a mechanism for small bowel resection-induced liver injury.
Volume: 323
Issue: 3
Pages: G165-G176
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Publication
25414185 | J:230989
First Author: Nashine S
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Role of C/EBP homologous protein in retinal ganglion cell death after ischemia/reperfusion injury.
Volume: 56
Issue: 1
Pages: 221-31
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Publication
28926118 | J:315597
First Author: Liu R
Year: 2018
Journal: Hepatology
Title: C/EBP homologous protein-induced loss of intestinal epithelial stemness contributes to bile duct ligation-induced cholestatic liver injury in mice.
Volume: 67
Issue: 4
Pages: 1441-1457
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Publication
23646198 | J:200547
First Author: Nashine S
Year: 2013
Journal: PLoS One
Title: Ablation of C/EBP homologous protein does not protect T17M RHO mice from retinal degeneration.
Volume: 8
Issue: 4
Pages: e63205
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Publication
24403532 | J:209401
First Author: Ferlito M
Year: 2014
Journal: J Immunol
Title: Hydrogen sulfide [corrected] increases survival during sepsis: protective effect of CHOP inhibition.
Volume: 192
Issue: 4
Pages: 1806-14
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Publication
26883801 | J:315412
First Author: Yao Y
Year: 2016
Journal: Mol Ther
Title: Chop Deficiency Protects Mice Against Bleomycin-induced Pulmonary Fibrosis by Attenuating M2 Macrophage Production.
Volume: 24
Issue: 5
Pages: 915-25
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Publication
27697863 | J:242999
First Author: Prasad M
Year: 2016
Journal: Mol Cell Biol
Title: Endoplasmic Reticulum Stress Enhances Mitochondrial Metabolic Activity in Mammalian Adrenals and Gonads.
Volume: 36
Issue: 24
Pages: 3058-3074
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Publication
27769859 | J:240813
First Author: Choi YY
Year: 2016
Journal: Biochem Biophys Res Commun
Title: CHOP deficiency inhibits methylglyoxal-induced endothelial dysfunction.
Volume: 480
Issue: 3
Pages: 362-368
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Publication
22815824 | J:189613
First Author: Chen CM
Year: 2012
Journal: PLoS One
Title: C/EBP homologous protein (CHOP) deficiency aggravates hippocampal cell apoptosis and impairs memory performance.
Volume: 7
Issue: 7
Pages: e40801
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Publication
16434966 | J:163135
First Author: Horndasch M
Year: 2006
Journal: Oncogene
Title: The C/EBP homologous protein CHOP (GADD153) is an inhibitor of Wnt/TCF signals.
Volume: 25
Issue: 24
Pages: 3397-407
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Publication
16621925 | J:109592
First Author: Pritsker M
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells.
Volume: 103
Issue: 18
Pages: 6946-51
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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