| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chlon TM |
| Year: |
2021 |
| Journal: |
Cell Stem Cell |
| Title: |
Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia. |
| Volume: |
28 |
| Issue: |
11 |
| Pages: |
1966-1981.e6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shinriki S |
| Year: |
2022 |
| Journal: |
Leukemia |
| Title: |
DDX41 coordinates RNA splicing and transcriptional elongation to prevent DNA replication stress in hematopoietic cells. |
| Volume: |
36 |
| Issue: |
11 |
| Pages: |
2605-2620 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ma J |
| Year: |
2022 |
| Journal: |
Stem Cell Reports |
| Title: |
DDX41 is needed for pre- and postnatal hematopoietic stem cell differentiation in mice. |
| Volume: |
17 |
| Issue: |
4 |
| Pages: |
879-893 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang Z |
| Year: |
2011 |
| Journal: |
Nat Immunol |
| Title: |
The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells. |
| Volume: |
12 |
| Issue: |
10 |
| Pages: |
959-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stepanchick E |
| Year: |
2024 |
| Journal: |
Leukemia |
| Title: |
DDX41 haploinsufficiency causes inefficient hematopoiesis under stress and cooperates with p53 mutations to cause hematologic malignancy. |
| Volume: |
38 |
| Issue: |
8 |
| Pages: |
1787-1798 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee KG |
| Year: |
2015 |
| Journal: |
Cell Rep |
| Title: |
Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response. |
| Volume: |
10 |
| Issue: |
7 |
| Pages: |
1055-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stavrou S |
| Year: |
2018 |
| Journal: |
MBio |
| Title: |
DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for In Vivo Control of Murine Leukemia Virus Infection. |
| Volume: |
9 |
| Issue: |
3 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Parvatiyar K |
| Year: |
2012 |
| Journal: |
Nat Immunol |
| Title: |
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. |
| Volume: |
13 |
| Issue: |
12 |
| Pages: |
1155-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang Z |
| Year: |
2013 |
| Journal: |
Nat Immunol |
| Title: |
The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA. |
| Volume: |
14 |
| Issue: |
2 |
| Pages: |
172-8 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3284528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6692035 |
| Age: |
postnatal adult |
| Image: |
TCP_2460006 |
|
| Specimen Label: |
TCP_2460006 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3284528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6692035 |
| Age: |
postnatal adult |
| Image: |
TCP_2460007 |
|
| Specimen Label: |
TCP_2460007 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3284528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6692035 |
| Age: |
postnatal adult |
| Image: |
TCP_2460003 |
|
| Specimen Label: |
TCP_2460003 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3284528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6692035 |
| Age: |
postnatal adult |
| Image: |
TCP_2460004 |
|
| Specimen Label: |
TCP_2460004 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3284528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6692035 |
| Age: |
postnatal adult |
| Image: |
TCP_2460005 |
|
| Specimen Label: |
TCP_2460005 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:532810 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824271 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000473_09 |
|
| Specimen Label: |
euxassay_000473_09 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:532810 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824271 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000473_10 |
|
| Specimen Label: |
euxassay_000473_10 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:532810 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824271 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000473_11 |
|
| Specimen Label: |
euxassay_000473_11 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:532810 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824271 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000473_12 |
|
| Specimen Label: |
euxassay_000473_12 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:532810 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824271 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000473_15 |
|
| Specimen Label: |
euxassay_000473_15 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:532810 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824271 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000473_16 |
|
| Specimen Label: |
euxassay_000473_16 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:532810 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824271 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000473_17 |
|
| Specimen Label: |
euxassay_000473_17 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:532810 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1797223 |
| Pattern: |
Spotted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824271 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000473_09 |
|
| Specimen Label: |
euxassay_000473_09 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:532810 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1797223 |
| Pattern: |
Spotted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824271 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000473_10 |
|
| Specimen Label: |
euxassay_000473_10 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:532810 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1797223 |
| Pattern: |
Spotted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824271 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000473_11 |
|
| Specimen Label: |
euxassay_000473_11 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:532810 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1797223 |
| Pattern: |
Spotted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824271 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000473_15 |
|
| Specimen Label: |
euxassay_000473_15 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:532810 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1797223 |
| Pattern: |
Spotted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824271 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000473_16 |
|
| Specimen Label: |
euxassay_000473_16 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:532810 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1797223 |
| Pattern: |
Spotted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4824271 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_000473_17 |
|
| Specimen Label: |
euxassay_000473_17 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nagamori I |
| Year: |
2006 |
| Journal: |
J Biol Chem |
| Title: |
Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation. |
| Volume: |
281 |
| Issue: |
22 |
| Pages: |
15073-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GO Central curators, GOA curators, Rhea curators |
| Year: |
2020 |
|
| Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dickinson ME |
| Year: |
2016 |
| Journal: |
Nature |
| Title: |
High-throughput discovery of novel developmental phenotypes. |
| Volume: |
537 |
| Issue: |
7621 |
| Pages: |
508-514 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators, MGI curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
FANTOM2 Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Koscielny G |
| Year: |
2014 |
| Journal: |
Nucleic Acids Res |
| Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
| Volume: |
42 |
| Issue: |
Database issue |
| Pages: |
D802-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stryke D |
| Year: |
2003 |
| Journal: |
Nucleic Acids Res |
| Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
| Volume: |
31 |
| Issue: |
1 |
| Pages: |
278-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Knockout Mouse Consortium |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lennon G |
| Year: |
1999 |
| Journal: |
Database Download |
| Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Mouse Strain Resource |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wellcome Trust Sanger Institute |
| Year: |
2009 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
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| UniProt Feature |
| Begin: |
1 |
| Description: |
Probable ATP-dependent RNA helicase DDX41 |
| Type: |
chain |
| End: |
622 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
622
 |
| Fragment?: |
false |
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Polprasert C |
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2015 |
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Cancer Cell |
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Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms. |
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5 |
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658-70 |
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