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Search results 1 to 100 out of 180 for Dennd1a

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
57706 | DENND1A
Type: gene
Organism: human
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Gene
100487210 | dennd1a
Type: gene
Organism: frog, western clawed
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Gene
311913 | Dennd1a
Type: gene
Organism: rat
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Gene
609706 | DENND1A
Type: gene
Organism: dog, domestic
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Gene
473055 | DENND1A
Type: gene
Organism: chimpanzee
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Gene
514134 | DENND1A
Type: gene
Organism: cattle
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Gene
417102 | DENND1A
Type: gene
Organism: chicken
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Gene
556150 | dennd1a
Type: gene
Organism: zebrafish
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Gene
698028 | DENND1A
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2442794 | Dennd1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
139355232 | DENND1A-AS1
Type: gene
Organism: human
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Publication
30884041 | J:276703
First Author: Shi J
Year: 2019
Journal: Dev Dyn
Title: Dennd1a, a susceptibility gene for polycystic ovary syndrome, is essential for mouse embryogenesis.
Volume: 248
Issue: 5
Pages: 351-362
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Protein Coding Gene
MGP_CAROLIEiJ_G0023523 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
ENSMUSG00200047268 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00195036644 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00220041800 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00180045730 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00175041404 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2442794 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00215044506 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSTCUG00005017606 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00210049504 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00185047239 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00205032466 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00230039462 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSUMUG00000011446 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00190039437 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00225048488 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSLUMG00010038548 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSIUOG00005038358 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024976 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
ENSMSPG00010037828 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:7264596
Assay Type: Western blot
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:7264622
Age: embryonic day 11.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7264596
Assay Type: Western blot
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:7264622
Age: embryonic day 11.5
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7264596
Assay Type: Western blot
Annotation Date: 2022-04-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:7264622
Age: embryonic day 11.5
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7264596
Assay Type: Western blot
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7264624
Age: embryonic day 13.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7264596
Assay Type: Western blot
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7264624
Age: embryonic day 13.5
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7264596
Assay Type: Western blot
Annotation Date: 2022-04-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7264624
Age: embryonic day 13.5
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7264611
Assay Type: RT-PCR
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:7264634
Age: embryonic day 9.5
Image: 2
Specimen Label: E9.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7264611
Assay Type: RT-PCR
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7264634
Age: embryonic day 10.5
Image: 2
Specimen Label: E10.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7264606
Assay Type: RNA in situ
Annotation Date: 2022-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1640615
Pattern: Widespread
Stage: TS15
Assay Id: MGI:7264630
Age: embryonic day 9.5
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7264606
Assay Type: RNA in situ
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Widespread
Stage: TS15
Assay Id: MGI:7264630
Age: embryonic day 9.5
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7264606
Assay Type: RNA in situ
Annotation Date: 2022-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Widespread
Stage: TS17
Assay Id: MGI:7264630
Age: embryonic day 10.5
Image: 2B
Specimen Label: 2B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7264606
Assay Type: RNA in situ
Annotation Date: 2022-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Widespread
Stage: TS15
Assay Id: MGI:7264630
Age: embryonic day 9.5
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7264606
Assay Type: RNA in situ
Annotation Date: 2022-04-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611715
Pattern: Widespread
Stage: TS15
Assay Id: MGI:7264630
Age: embryonic day 9.5
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
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Publication
20159556 | J:229372
First Author: Allaire PD
Year: 2010
Journal: Mol Cell
Title: The Connecdenn DENN domain: a GEF for Rab35 mediating cargo-specific exit from early endosomes.
Volume: 37
Issue: 3
Pages: 370-82
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Publication
32238901 | J:370717
First Author: Wang Y
Year: 2020
Journal: Cell Res
Title: Accelerated evolution of an Lhx2 enhancer shapes mammalian social hierarchies.
Volume: 30
Issue: 5
Pages: 408-420
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Publication
17182770 | J:116685
First Author: Allaire PD
Year: 2006
Journal: J Neurosci
Title: Connecdenn, a novel DENN domain-containing protein of neuronal clathrin-coated vesicles functioning in synaptic vesicle endocytosis.
Volume: 26
Issue: 51
Pages: 13202-12
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:384794
     
First Author: MGI and IMPC
Year: 2026
Journal: Database Release
Title: MGI Load of Molecular Notes for Endonuclease-Mediated (CRISPR) Alleles from the International Mouse Phenotyping Consortium (IMPC)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342609
       
First Author: UniProt
Year: 2021
Title: Electronic Gene Ontology annotations created by ARBA machine learning models
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:389486
     
First Author: Mouse Genome Informatics and Ensembl Genome Database Project
Year: 2026
Journal: Database Release
Title: MGI Strain Genome Feature and Gene Model Load from Ensembl.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Allele
Dennd1a<em1Smoc> | MGI:7289312
Name: DENN domain containing 1A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6428529 | C57BL/6JSmoc-Dennd1a<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Igs2<tm2(Rr555999-lacZ)Kco> | MGI:8245534
Name: intergenic site 2; targeted mutation 2, Kerby C Oberg
Allele Type: Targeted
Attribute String: Reporter
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Allele
Igs2<tm1(Rr556004-lacZ)Kco> | MGI:8245533
Name: intergenic site 2; targeted mutation 1, Kerby C Oberg
Allele Type: Targeted
Attribute String: Reporter
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Publication
40052149 | J:362224
 
First Author: Britton JC
Year: 2025
Journal: Front Cell Dev Biol
Title: Evidence for Fgf and Wnt regulation of Lhx2 during limb development via two limb-specific Lhx2-associated cis-regulatory modules.
Volume: 13
Pages: 1552716
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Publication
20154091 | -
First Author: Marat AL
Year: 2010
Journal: J Biol Chem
Title: The connecdenn family, Rab35 guanine nucleotide exchange factors interfacing with the clathrin machinery.
Volume: 285
Issue: 14
Pages: 10627-37
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Protein
A0A0G2JGT6
Organism: Mus musculus/domesticus
Length: 47  
Fragment?: false
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Protein
A0A3B2WB03
Organism: Mus musculus/domesticus
Length: 61  
Fragment?: false
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Protein
A2ALU3
Organism: Mus musculus/domesticus
Length: 277  
Fragment?: true
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Protein
C6EQJ8
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
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Protein
D6RI65
Organism: Mus musculus/domesticus
Length: 47  
Fragment?: false
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Protein Domain
IPR040032 | DENND1A/B/C
Type: Family
Description: This entry includes proteins containing an N-terminal tripartite DENN domain, including DENND1A (also known as connecdenn 1), DENND1B (connecdenn 2) and DENND1C (connecdenn 3). These proteins act as guanine-nucleotide exchange factors for Rab35 through the DENN domain. Inactive GDP-bound RAB35 is converted into its active GTP-bound form by the exchange of GDP to GTP. The DENN domains of DENND1A and DENND1B, but not DENND1C, bind Rab35, indicating that binding and activation are separate. The C-termini of DENND1A, DENND1B and DENND1C differ significantly, but each binds to clathrin and to the clathrin adaptor AP-2. This is a means to regulate clathrin-mediated endocytosis of synaptic vesicles and exit from early endosomes [].
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Protein
A2AUP6
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
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Protein
D6RH88
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: false
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Protein
Q8R1W1
Organism: Mus musculus/domesticus
Length: 224  
Fragment?: false
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Protein
A0A0G2JH11
Organism: Mus musculus/domesticus
Length: 352  
Fragment?: false
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Protein
Q3U1T9
Organism: Mus musculus/domesticus
Length: 766  
Fragment?: false
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Protein
Q8K382
Organism: Mus musculus/domesticus
Length: 1016  
Fragment?: false
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Protein
Q8CFK6
Organism: Mus musculus/domesticus
Length: 786  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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