| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6171821 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2022-06-30 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7294512 |
| Age: |
postnatal day 56 |
| Image: |
S3 EHBP1 |
|
| Specimen Label: |
S3 EHBP1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ma F |
| Year: |
2025 |
| Journal: |
Cell Metab |
| Title: |
EHBP1 suppresses liver fibrosis in metabolic dysfunction-associated steatohepatitis. |
| Volume: |
37 |
| Issue: |
5 |
| Pages: |
1152-1170.e7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guilherme A |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton. |
| Volume: |
279 |
| Issue: |
11 |
| Pages: |
10593-605 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guilherme A |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes. |
| Volume: |
279 |
| Issue: |
38 |
| Pages: |
40062-75 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4415979 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2022-06-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689422 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7294502 |
| Age: |
embryonic day 14.5 |
| Image: |
S2 EHBP1 |
|
| Specimen Label: |
S2 EHBP1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6437573 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2026-06-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1637015 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:8351304 |
| Age: |
embryonic day 9.5 |
| Image: |
Ehbp1 -/- E9.5 |
| Note: |
Expression is seen in the fetal vascular network within the labyrinthine zone; in the mutant this network is comparable to that seen in controls. |
| Specimen Label: |
Ehbp1 -/- E9.5 |
| Detected: |
true |
| Specimen Num: |
20 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6437573 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2026-06-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1637015 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:8351304 |
| Age: |
embryonic day 9.5 |
| Image: |
Ehbp1 +/- E9.5 |
| Note: |
Expression is seen in the fetal vascular network within the labyrinthine zone. |
| Specimen Label: |
Ehbp1 +/- E9.5 |
| Detected: |
true |
| Specimen Num: |
19 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8261090 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2026-06-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3187815 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:8350480 |
| Age: |
embryonic day 9.5 |
| Image: |
Ehbp1 -/- E9.5 |
| Note: |
Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls. (A slight reduction in the layer was observed but was attributed to the developmental delay of the conceptus.) |
| Specimen Label: |
Ehbp1 -/- E9.5 |
| Detected: |
true |
| Specimen Num: |
22 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8261069 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2026-06-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3187815 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:8350479 |
| Age: |
embryonic day 9.5 |
| Image: |
Ehbp1 -/- E9.5 |
| Note: |
Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development is comparable to that seen in controls. (A slight reduction in the SynTII layer was observed but was attributed to the developmental delay of the conceptus.) |
| Specimen Label: |
Ehbp1 -/- E9.5 |
| Detected: |
true |
| Specimen Num: |
22 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6403435 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2026-06-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3187815 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:8350550 |
| Age: |
embryonic day 9.5 |
| Image: |
Ehbp1 -/- E9.5 |
| Note: |
Expression is seen in mature SynTI cells; in mutants this layer is comparable to that seen in controls. |
| Specimen Label: |
Ehbp1 -/- E9.5 |
| Detected: |
true |
| Specimen Num: |
20 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6403438 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2026-06-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3187815 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:8350556 |
| Age: |
embryonic day 9.5 |
| Image: |
Ehbp1 -/- E9.5 |
| Note: |
Expression is seen in mature SynTII cells; in the mutant chorioallantoic branching and SynTII layer formation is comparable to that seen in controls. (A slight reduction in the SynTII layer was observed but was attributed to the developmental delay of the conceptus.) |
| Specimen Label: |
Ehbp1 -/- E9.5 |
| Detected: |
true |
| Specimen Num: |
20 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6403438 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2026-06-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3187815 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:8350556 |
| Age: |
embryonic day 9.5 |
| Image: |
Ehbp1 +/- E9.5 |
| Note: |
Expression is seen in mature SynTII cells. |
| Specimen Label: |
Ehbp1 +/- E9.5 |
| Detected: |
true |
| Specimen Num: |
19 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8261090 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2026-06-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3187815 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:8350480 |
| Age: |
embryonic day 9.5 |
| Image: |
Ehbp1 +/- E9.5 |
| Note: |
Expression is seen in SynTI cells and precursors. |
| Specimen Label: |
Ehbp1 +/- E9.5 |
| Detected: |
true |
| Specimen Num: |
21 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6403435 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2026-06-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3187815 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:8350550 |
| Age: |
embryonic day 9.5 |
| Image: |
Ehbp1 +/- E9.5 |
| Note: |
Expression is seen in mature SynTI cells. |
| Specimen Label: |
Ehbp1 +/- E9.5 |
| Detected: |
true |
| Specimen Num: |
19 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8261069 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2026-06-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3187815 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:8350479 |
| Age: |
embryonic day 9.5 |
| Image: |
Ehbp1 +/- E9.5 |
| Note: |
Expression is seen in a subset of SynTII cells and precursors. |
| Specimen Label: |
Ehbp1 +/- E9.5 |
| Detected: |
true |
| Specimen Num: |
21 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8261083 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2026-06-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3187615 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:8350481 |
| Age: |
embryonic day 9.5 |
| Image: |
Ehbp1 -/- E9.5 |
| Note: |
In mutants this layer is comparable to that seen in controls. |
| Specimen Label: |
Ehbp1 -/- E9.5 |
| Detected: |
true |
| Specimen Num: |
17 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8261083 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2026-06-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3187615 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:8350481 |
| Age: |
embryonic day 9.5 |
| Image: |
Ehbp1 +/- E9.5 |
|
| Specimen Label: |
Ehbp1 +/- E9.5 |
| Detected: |
true |
| Specimen Num: |
16 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fuchs S |
| Year: |
2001 |
| Journal: |
GenBank Submission |
| Title: |
Mus musculus KIAA0903-like protein mRNA, complete cds |
|
|
| Pages: |
AF424697 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakajo A |
| Year: |
2016 |
| Journal: |
J Cell Biol |
| Title: |
EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells. |
| Volume: |
212 |
| Issue: |
3 |
| Pages: |
297-306 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fuchs S |
| Year: |
2002 |
| Journal: |
BMC Genet |
| Title: |
Comparative transcription map of the wobbler critical region on mouse chromosome 11 and the homologous region on human chromosome 2p13-14. |
| Volume: |
3 |
|
| Pages: |
14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Urbanek ME |
| Year: |
2021 |
| Journal: |
Sci Rep |
| Title: |
Genetic predisposition to tinnitus in the UK Biobank population. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
18150 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guertin TM |
| Year: |
2026 |
| Journal: |
Development |
| Title: |
Onset of embryonic and placental defects coincide in 19 of 22 novel mid-gestation lethal murine knockout lines. |
| Volume: |
153 |
| Issue: |
10 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tremblay KD |
| Year: |
2025 |
| Journal: |
MGI Direct Data Submission |
| Title: |
A Catalog of Novel Organogenesis Lethal KOMP Phenotypes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bulfone A |
| Year: |
2005 |
| Journal: |
J Neurosci |
| Title: |
Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. |
| Volume: |
25 |
| Issue: |
33 |
| Pages: |
7586-600 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Araki K |
| Year: |
1999 |
| Journal: |
Cell Mol Biol (Noisy-le-grand) |
| Title: |
Exchangeable gene trap using the Cre/mutated lox system. |
| Volume: |
45 |
| Issue: |
5 |
| Pages: |
737-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Taniwaki T |
| Year: |
2005 |
| Journal: |
Dev Growth Differ |
| Title: |
Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. |
| Volume: |
47 |
| Issue: |
3 |
| Pages: |
163-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
MGC Data curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory |
| Year: |
2012 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by The Jackson Laboratory |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stryke D |
| Year: |
2003 |
| Journal: |
Nucleic Acids Res |
| Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
| Volume: |
31 |
| Issue: |
1 |
| Pages: |
278-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wellcome Trust Sanger Institute |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI and IMPC |
| Year: |
2026 |
| Journal: |
Database Release |
| Title: |
MGI Load of Molecular Notes for Endonuclease-Mediated (CRISPR) Alleles from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
| Pages: |
1670-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helmholtz Zentrum Muenchen GmbH |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skarnes WC |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
| Volume: |
474 |
| Issue: |
7351 |
| Pages: |
337-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
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| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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•
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| Publication |
| First Author: |
UniProt |
| Year: |
2021 |
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| Title: |
Electronic Gene Ontology annotations created by ARBA machine learning models |
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•
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| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
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•
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| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
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| Title: |
GemPharmatech Website. |
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•
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| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
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| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
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| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
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•
•
•
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| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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•
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| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
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| Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
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•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
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•
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•
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•
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| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
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•
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•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
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•
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•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
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| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
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•
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•
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| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
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•
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| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
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| Publication |
| First Author: |
Li Z |
| Year: |
2016 |
| Journal: |
Sci Adv |
| Title: |
A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets. |
| Volume: |
2 |
| Issue: |
12 |
| Pages: |
e1601470 |
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•
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•
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| Publication |
| First Author: |
Eguchi T |
| Year: |
2018 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis. |
| Volume: |
115 |
| Issue: |
39 |
| Pages: |
E9115-E9124 |
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•
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
392
 |
| Fragment?: |
false |
|
•
•
•
•
•
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
339
 |
| Fragment?: |
false |
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•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
392
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
73
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
370
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang P |
| Year: |
2016 |
| Journal: |
PLoS Genet |
| Title: |
RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes. |
| Volume: |
12 |
| Issue: |
6 |
| Pages: |
e1006093 |
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•
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•
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| Protein Domain |
| Type: |
Domain |
| Description: |
The C2 domain is one of the most prevalent eukaryotic lipid-binding domains deployed in diverse functional contexts. Many C2 domains bind directly to membrane lipids and display a wide range of lipid selectivity, with preference for anionic phosphatidylserine (PS) and phosphatidylinositol-phosphates (PIPs).Despite their limited sequence similarity, all C2 domains contain at their core a compact ��-sandwich composed of two four-stranded �� sheets with highly variable inter-strand regions that might contain one or more alpha- helices.The NT-type C2 domain shows a diverse range of domain architectures but it is nearly always found at the N-termini of proteins that contain it. Hence, it has been named the N-terminal C2 (NT-C2) family. It is typically coupled with a coiled-coil domain, that could mediate di/oligo-merization and the DIL (Dilute) domain. It is also coupled with the Calponin homology (CH) domain in EHBP1 proteins, Filamin/ABP280 repeats and Mg2+ transporter MgtE N-terminal domain in proteins from chlorophyte algae such as Micromonas and Ostreococcus tauri. Thus, a common theme across the NT-type C2 domain proteins is the combination to several different domains with microfilament-binding or actin-related roles (i.e. such as CH, DIL, and Filamin). Other conserved groups of the NT-type C2 proteins prototyped by EEIG1, PMI1, and SYNC1 have their own distinct C- terminal conserved extensions that are restricted to these groups and might mediate specific interactions. The primary function of the NT-type C2 domain appears to be the linking of actin/microfilament-binding adaptors to the membrane and to act as a link that tethers endosomal vesicles to the cytoskeleton in course of their intracellular trafficking [, ]. |
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•
•
•
•
•
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
308
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang D |
| Year: |
2010 |
| Journal: |
Gene |
| Title: |
Identification of novel families and classification of the C2 domain superfamily elucidate the origin and evolution of membrane targeting activities in eukaryotes. |
| Volume: |
469 |
| Issue: |
1-2 |
| Pages: |
18-30 |
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