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Search results 1 to 100 out of 107 for Ehbp1

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Type Details Score
Gene
Type: gene
Organism: human
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Gene
Type: gene
Organism: frog, western clawed
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Gene
Type: gene
Organism: rat
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Gene
Type: gene
Organism: dog, domestic
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Gene
Type: gene
Organism: chimpanzee
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Gene
Type: gene
Organism: cattle
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Gene
Type: gene
Organism: chicken
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Gene
Type: gene
Organism: zebrafish
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Gene
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression  
Probe: MGI:6171821
Assay Type: RNA in situ
Annotation Date: 2022-06-30
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7294512
Age: postnatal day 56
Image: S3 EHBP1
Specimen Label: S3 EHBP1
Detected: true
Specimen Num: 1
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Gene
Type: gene
Organism: human
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Publication
First Author: Ma F
Year: 2025
Journal: Cell Metab
Title: EHBP1 suppresses liver fibrosis in metabolic dysfunction-associated steatohepatitis.
Volume: 37
Issue: 5
Pages: 1152-1170.e7
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Publication
First Author: Guilherme A
Year: 2004
Journal: J Biol Chem
Title: EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton.
Volume: 279
Issue: 11
Pages: 10593-605
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Publication
First Author: Guilherme A
Year: 2004
Journal: J Biol Chem
Title: Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes.
Volume: 279
Issue: 38
Pages: 40062-75
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GXD Expression  
Probe: MGI:4415979
Assay Type: RNA in situ
Annotation Date: 2022-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7294502
Age: embryonic day 14.5
Image: S2 EHBP1
Specimen Label: S2 EHBP1
Detected: true
Specimen Num: 1
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GXD Expression
Probe: MGI:6437573
Assay Type: Immunohistochemistry
Annotation Date: 2026-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1637015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:8351304
Age: embryonic day 9.5
Image: Ehbp1 -/- E9.5
Note: Expression is seen in the fetal vascular network within the labyrinthine zone; in the mutant this network is comparable to that seen in controls.
Specimen Label: Ehbp1 -/- E9.5
Detected: true
Specimen Num: 20
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GXD Expression
Probe: MGI:6437573
Assay Type: Immunohistochemistry
Annotation Date: 2026-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1637015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:8351304
Age: embryonic day 9.5
Image: Ehbp1 +/- E9.5
Note: Expression is seen in the fetal vascular network within the labyrinthine zone.
Specimen Label: Ehbp1 +/- E9.5
Detected: true
Specimen Num: 19
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GXD Expression
Probe: MGI:8261090
Assay Type: RNA in situ
Annotation Date: 2026-06-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:8350480
Age: embryonic day 9.5
Image: Ehbp1 -/- E9.5
Note: Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls. (A slight reduction in the layer was observed but was attributed to the developmental delay of the conceptus.)
Specimen Label: Ehbp1 -/- E9.5
Detected: true
Specimen Num: 22
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GXD Expression
Probe: MGI:8261069
Assay Type: RNA in situ
Annotation Date: 2026-06-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:8350479
Age: embryonic day 9.5
Image: Ehbp1 -/- E9.5
Note: Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development is comparable to that seen in controls. (A slight reduction in the SynTII layer was observed but was attributed to the developmental delay of the conceptus.)
Specimen Label: Ehbp1 -/- E9.5
Detected: true
Specimen Num: 22
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GXD Expression
Probe: MGI:6403435
Assay Type: Immunohistochemistry
Annotation Date: 2026-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:8350550
Age: embryonic day 9.5
Image: Ehbp1 -/- E9.5
Note: Expression is seen in mature SynTI cells; in mutants this layer is comparable to that seen in controls.
Specimen Label: Ehbp1 -/- E9.5
Detected: true
Specimen Num: 20
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GXD Expression
Probe: MGI:6403438
Assay Type: Immunohistochemistry
Annotation Date: 2026-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:8350556
Age: embryonic day 9.5
Image: Ehbp1 -/- E9.5
Note: Expression is seen in mature SynTII cells; in the mutant chorioallantoic branching and SynTII layer formation is comparable to that seen in controls. (A slight reduction in the SynTII layer was observed but was attributed to the developmental delay of the conceptus.)
Specimen Label: Ehbp1 -/- E9.5
Detected: true
Specimen Num: 20
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GXD Expression
Probe: MGI:6403438
Assay Type: Immunohistochemistry
Annotation Date: 2026-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:8350556
Age: embryonic day 9.5
Image: Ehbp1 +/- E9.5
Note: Expression is seen in mature SynTII cells.
Specimen Label: Ehbp1 +/- E9.5
Detected: true
Specimen Num: 19
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GXD Expression
Probe: MGI:8261090
Assay Type: RNA in situ
Annotation Date: 2026-06-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:8350480
Age: embryonic day 9.5
Image: Ehbp1 +/- E9.5
Note: Expression is seen in SynTI cells and precursors.
Specimen Label: Ehbp1 +/- E9.5
Detected: true
Specimen Num: 21
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GXD Expression
Probe: MGI:6403435
Assay Type: Immunohistochemistry
Annotation Date: 2026-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:8350550
Age: embryonic day 9.5
Image: Ehbp1 +/- E9.5
Note: Expression is seen in mature SynTI cells.
Specimen Label: Ehbp1 +/- E9.5
Detected: true
Specimen Num: 19
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GXD Expression
Probe: MGI:8261069
Assay Type: RNA in situ
Annotation Date: 2026-06-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:8350479
Age: embryonic day 9.5
Image: Ehbp1 +/- E9.5
Note: Expression is seen in a subset of SynTII cells and precursors.
Specimen Label: Ehbp1 +/- E9.5
Detected: true
Specimen Num: 21
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GXD Expression
Probe: MGI:8261083
Assay Type: RNA in situ
Annotation Date: 2026-06-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187615
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:8350481
Age: embryonic day 9.5
Image: Ehbp1 -/- E9.5
Note: In mutants this layer is comparable to that seen in controls.
Specimen Label: Ehbp1 -/- E9.5
Detected: true
Specimen Num: 17
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GXD Expression  
Probe: MGI:8261083
Assay Type: RNA in situ
Annotation Date: 2026-06-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187615
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:8350481
Age: embryonic day 9.5
Image: Ehbp1 +/- E9.5
Specimen Label: Ehbp1 +/- E9.5
Detected: true
Specimen Num: 16
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
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Publication    
First Author: Fuchs S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus KIAA0903-like protein mRNA, complete cds
Pages: AF424697
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Publication
First Author: Nakajo A
Year: 2016
Journal: J Cell Biol
Title: EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells.
Volume: 212
Issue: 3
Pages: 297-306
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Publication  
First Author: Fuchs S
Year: 2002
Journal: BMC Genet
Title: Comparative transcription map of the wobbler critical region on mouse chromosome 11 and the homologous region on human chromosome 2p13-14.
Volume: 3
Pages: 14
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Publication
First Author: Urbanek ME
Year: 2021
Journal: Sci Rep
Title: Genetic predisposition to tinnitus in the UK Biobank population.
Volume: 11
Issue: 1
Pages: 18150
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Publication  
First Author: Guertin TM
Year: 2026
Journal: Development
Title: Onset of embryonic and placental defects coincide in 19 of 22 novel mid-gestation lethal murine knockout lines.
Volume: 153
Issue: 10
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Publication      
First Author: Tremblay KD
Year: 2025
Journal: MGI Direct Data Submission
Title: A Catalog of Novel Organogenesis Lethal KOMP Phenotypes
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Publication
First Author: Bulfone A
Year: 2005
Journal: J Neurosci
Title: Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Volume: 25
Issue: 33
Pages: 7586-600
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Publication
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication      
First Author: MGI and IMPC
Year: 2026
Journal: Database Release
Title: MGI Load of Molecular Notes for Endonuclease-Mediated (CRISPR) Alleles from the International Mouse Phenotyping Consortium (IMPC)
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Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication        
First Author: UniProt
Year: 2021
Title: Electronic Gene Ontology annotations created by ARBA machine learning models
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Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
First Author: Li Z
Year: 2016
Journal: Sci Adv
Title: A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets.
Volume: 2
Issue: 12
Pages: e1601470
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Publication
First Author: Eguchi T
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: LRRK2 and its substrate Rab GTPases are sequentially targeted onto stressed lysosomes and maintain their homeostasis.
Volume: 115
Issue: 39
Pages: E9115-E9124
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Protein
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 339  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 73  
Fragment?: true
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Protein
Organism: Mus musculus/domesticus
Length: 370  
Fragment?: false
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Publication
First Author: Wang P
Year: 2016
Journal: PLoS Genet
Title: RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes.
Volume: 12
Issue: 6
Pages: e1006093
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Protein Domain
Type: Domain
Description: The C2 domain is one of the most prevalent eukaryotic lipid-binding domains deployed in diverse functional contexts. Many C2 domains bind directly to membrane lipids and display a wide range of lipid selectivity, with preference for anionic phosphatidylserine (PS) and phosphatidylinositol-phosphates (PIPs).Despite their limited sequence similarity, all C2 domains contain at their core a compact ��-sandwich composed of two four-stranded �� sheets with highly variable inter-strand regions that might contain one or more alpha- helices.The NT-type C2 domain shows a diverse range of domain architectures but it is nearly always found at the N-termini of proteins that contain it. Hence, it has been named the N-terminal C2 (NT-C2) family. It is typically coupled with a coiled-coil domain, that could mediate di/oligo-merization and the DIL (Dilute) domain. It is also coupled with the Calponin homology (CH) domain in EHBP1 proteins, Filamin/ABP280 repeats and Mg2+ transporter MgtE N-terminal domain in proteins from chlorophyte algae such as Micromonas and Ostreococcus tauri. Thus, a common theme across the NT-type C2 domain proteins is the combination to several different domains with microfilament-binding or actin-related roles (i.e. such as CH, DIL, and Filamin). Other conserved groups of the NT-type C2 proteins prototyped by EEIG1, PMI1, and SYNC1 have their own distinct C- terminal conserved extensions that are restricted to these groups and might mediate specific interactions. The primary function of the NT-type C2 domain appears to be the linking of actin/microfilament-binding adaptors to the membrane and to act as a link that tethers endosomal vesicles to the cytoskeleton in course of their intracellular trafficking [, ].
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Protein
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: true
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Publication
First Author: Zhang D
Year: 2010
Journal: Gene
Title: Identification of novel families and classification of the C2 domain superfamily elucidate the origin and evolution of membrane targeting activities in eukaryotes.
Volume: 469
Issue: 1-2
Pages: 18-30
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