Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Eukaryotic translation initiation factor 3 subunit F is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome [, ]. In humans, it exhibits a deubiquitinase activity regulating Notch activation []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Moretti J |
Year: |
2010 |
Journal: |
PLoS Biol |
Title: |
The translation initiation factor 3f (eIF3f) exhibits a deubiquitinase activity regulating Notch activation. |
Volume: |
8 |
Issue: |
11 |
Pages: |
e1000545 |
|
•
•
•
•
•
|
Publication |
First Author: |
Docquier A |
Year: |
2019 |
Journal: |
J Physiol |
Title: |
eIF3f depletion impedes mouse embryonic development, reduces adult skeletal muscle mass and amplifies muscle loss during disuse. |
Volume: |
597 |
Issue: |
12 |
Pages: |
3107-3131 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
361
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
361
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
361
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
360
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
361
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
148
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
50
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Asano K |
Year: |
1997 |
Journal: |
J Biol Chem |
Title: |
Conservation and diversity of eukaryotic translation initiation factor eIF3. |
Volume: |
272 |
Issue: |
2 |
Pages: |
1101-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou C |
Year: |
2005 |
Journal: |
BMC Biol |
Title: |
PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes. |
Volume: |
3 |
|
Pages: |
14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zeng L |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control. |
Volume: |
288 |
Issue: |
42 |
Pages: |
30087-93 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7332874 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1611715 |
|
Stage: |
TS15 |
Assay Id: |
MGI:7332892 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7332874 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1611715 |
|
Stage: |
TS15 |
Assay Id: |
MGI:7332892 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
Yy1 cko |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7333055 |
Assay Type: |
Western blot |
Annotation Date: |
2022-09-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603915 |
|
Stage: |
TS15 |
Assay Id: |
MGI:7333075 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
Wildtype |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7333055 |
Assay Type: |
Western blot |
Annotation Date: |
2022-09-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603915 |
|
Stage: |
TS15 |
Assay Id: |
MGI:7333075 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
Eif3cXs-J/+ |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7333055 |
Assay Type: |
Western blot |
Annotation Date: |
2022-09-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603915 |
|
Stage: |
TS15 |
Assay Id: |
MGI:7333075 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
Wildtype |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7333055 |
Assay Type: |
Western blot |
Annotation Date: |
2022-09-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603915 |
|
Stage: |
TS15 |
Assay Id: |
MGI:7333075 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
Eif3cXs-J/+ |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2769723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539683 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6045 |
|
Specimen Label: |
GUDMAP:6045 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-03-30 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3152723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:6513299 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S1 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4428913 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-04-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7621783 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2853323 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539683 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6045 |
|
Specimen Label: |
GUDMAP:6045 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2845723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539683 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6045 |
|
Specimen Label: |
GUDMAP:6045 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1795023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5539683 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6045 |
|
Specimen Label: |
GUDMAP:6045 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1869223 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539683 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6045 |
|
Specimen Label: |
GUDMAP:6045 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2004-12-03 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1647017 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:3509382 |
Age: |
embryonic day 10.5 |
Image: |
1 |
Note: |
Authors stated that in some instances they could not determine expression levels with certainty. |
Specimen Label: |
1 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2762123 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539683 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6045 |
|
Specimen Label: |
GUDMAP:6045 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797223 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539683 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6045 |
|
Specimen Label: |
GUDMAP:6045 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1832123 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5539683 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6045 |
|
Specimen Label: |
GUDMAP:6045 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4428913 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-04-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7621783 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2851823 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539683 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6045 |
|
Specimen Label: |
GUDMAP:6045 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2760523 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539683 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6045 |
|
Specimen Label: |
GUDMAP:6045 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2852723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539683 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6045 |
|
Specimen Label: |
GUDMAP:6045 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3506704 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2850023 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:5539683 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:6045 |
|
Specimen Label: |
GUDMAP:6045 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lagirand-Cantaloube J |
Year: |
2008 |
Journal: |
EMBO J |
Title: |
The initiation factor eIF3-f is a major target for atrogin1/MAFbx function in skeletal muscle atrophy. |
Volume: |
27 |
Issue: |
8 |
Pages: |
1266-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Min SH |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Altered levels of growth-related and novel gene transcripts in reproductive and other tissues of female mice overexpressing spermidine/spermine N1-acetyltransferase (SSAT). |
Volume: |
277 |
Issue: |
5 |
Pages: |
3647-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Harris TE |
Year: |
2006 |
Journal: |
EMBO J |
Title: |
mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin. |
Volume: |
25 |
Issue: |
8 |
Pages: |
1659-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Masutani M |
Year: |
2007 |
Journal: |
EMBO J |
Title: |
Reconstitution reveals the functional core of mammalian eIF3. |
Volume: |
26 |
Issue: |
14 |
Pages: |
3373-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fujii K |
Year: |
2021 |
Journal: |
Dev Cell |
Title: |
Controlling tissue patterning by translational regulation of signaling transcripts through the core translation factor eIF3c. |
Volume: |
56 |
Issue: |
21 |
Pages: |
2928-2937.e9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Varum S |
Year: |
2019 |
Journal: |
Cell Stem Cell |
Title: |
Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation. |
Volume: |
24 |
Issue: |
4 |
Pages: |
637-653.e9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tkatchenko TV |
Year: |
2009 |
Journal: |
Physiol Genomics |
Title: |
Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease. |
Volume: |
39 |
Issue: |
3 |
Pages: |
160-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Distler U |
Year: |
2014 |
Journal: |
Proteomics |
Title: |
In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics. |
Volume: |
14 |
Issue: |
21-22 |
Pages: |
2607-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt curators |
Year: |
2014 |
|
Title: |
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wiese CB |
Year: |
2012 |
Journal: |
Front Neurosci |
Title: |
A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. |
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Mouse Genome Informatics Scientific Curators |
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2001 |
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Title: |
RIKEN Data Curation in Mouse Genome Informatics |
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MGI and IMPC |
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2018 |
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Database Release |
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Science |
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Mouse brain organization revealed through direct genome-scale TF expression analysis. |
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Front Mol Neurosci |
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Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
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First Author: |
Velocigene |
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2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
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GUDMAP Consortium |
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2004 |
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GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
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Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
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Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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Science |
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The transcriptional landscape of the mammalian genome. |
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2001 |
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Nature |
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Functional annotation of a full-length mouse cDNA collection. |
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Nature |
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MGD Nomenclature Committee |
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Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
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Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
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2008 |
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Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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GOA curators |
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2016 |
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Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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The Jackson Laboratory Mouse Radiation Hybrid Database |
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Database Release |
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Mouse T31 Radiation Hybrid Data Load |
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2002 |
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Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
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The Gene Ontology Consortium |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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PLoS Biol |
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A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
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Mouse Genome Informatics Scientific Curators |
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2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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Mouse Genome Informatics Scientific Curators |
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2010 |
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Database Download |
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Database Download |
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2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Mouse Genome Database and National Center for Biotechnology Information |
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Database Release |
Title: |
Entrez Gene Load |
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