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Search results 1 to 100 out of 147 for Eif4ebp2

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Hits by Category

Hits by Strain

Type Details Score
Gene
1979 | EIF4EBP2
Type: gene
Organism: human
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Gene
394958 | eif4ebp2
Type: gene
Organism: frog, western clawed
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Gene
361845 | Eif4ebp2
Type: gene
Organism: rat
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Gene
489027 | EIF4EBP2
Type: gene
Organism: dog, domestic
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Gene
782397 | EIF4EBP2
Type: gene
Organism: cattle
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Gene
100610028 | EIF4EBP2
Type: gene
Organism: chimpanzee
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Gene
769479 | EIF4EBP2
Type: gene
Organism: chicken
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Gene
386945 | eif4ebp2
Type: gene
Organism: zebrafish
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Gene
100424761 | EIF4EBP2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:109198 | Eif4ebp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0015367 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017280 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017258 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017041 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_109198 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017676 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016612 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017013 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017118 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017112 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017193 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017140 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017714 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016395 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016676 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030783 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016178 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16237163 | J:102163
First Author: Banko JL
Year: 2005
Journal: J Neurosci
Title: The translation repressor 4E-BP2 is critical for eIF4F complex formation, synaptic plasticity, and memory in the hippocampus.
Volume: 25
Issue: 42
Pages: 9581-90
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Publication
17029989 | J:128841
First Author: Banko JL
Year: 2007
Journal: Neurobiol Learn Mem
Title: Behavioral alterations in mice lacking the translation repressor 4E-BP2.
Volume: 87
Issue: 2
Pages: 248-56
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Publication
7935836 | J:41738
First Author: Pause A
Year: 1994
Journal: Nature
Title: Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function.
Volume: 371
Issue: 6500
Pages: 762-7
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Publication
33910008 | J:337368
First Author: Hooshmandi M
Year: 2021
Journal: Cell Rep
Title: 4E-BP2-dependent translation in cerebellar Purkinje cells controls spatial memory but not autism-like behaviors.
Volume: 35
Issue: 4
Pages: 109036
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Publication
23365227 | J:193890
First Author: Ran I
Year: 2013
Journal: J Neurosci
Title: Selective regulation of GluA subunit synthesis and AMPA receptor-mediated synaptic function and plasticity by the translation repressor 4E-BP2 in hippocampal pyramidal cells.
Volume: 33
Issue: 5
Pages: 1872-86
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Publication
34326413 | J:359849
First Author: Roque PS
Year: 2021
Journal: Sci Rep
Title: Intranasal insulin rescues repeated anesthesia-induced deficits in synaptic plasticity and memory and prevents apoptosis in neonatal mice via mTORC1.
Volume: 11
Issue: 1
Pages: 15490
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Publication
26245973 | J:225875
First Author: Aguilar-Valles A
Year: 2015
Journal: J Neurosci
Title: Inhibition of Group I Metabotropic Glutamate Receptors Reverses Autistic-Like Phenotypes Caused by Deficiency of the Translation Repressor eIF4E Binding Protein 2.
Volume: 35
Issue: 31
Pages: 11125-32
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GXD Expression
GXD Expression
     
Probe: MGI:5708400
Assay Type: Western blot
Annotation Date: 2016-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5708505
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5708400
Assay Type: Western blot
Annotation Date: 2016-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5708505
Age: postnatal adult
Specimen Label: Eif4e+/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5708400
Assay Type: Western blot
Annotation Date: 2016-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5708505
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5708400
Assay Type: Western blot
Annotation Date: 2016-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5708505
Age: postnatal adult
Specimen Label: Eif4e+/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5708400
Assay Type: Western blot
Annotation Date: 2016-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5708505
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5708400
Assay Type: Western blot
Annotation Date: 2016-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5708505
Age: postnatal adult
Specimen Label: Eif4e+/-
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:5708525
Assay Type: Western blot
Annotation Date: 2016-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5708527
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5708525
Assay Type: Western blot
Annotation Date: 2016-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5708527
Age: postnatal adult
Specimen Label: Eif4e+/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5708525
Assay Type: Western blot
Annotation Date: 2016-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5708527
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5708525
Assay Type: Western blot
Annotation Date: 2016-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5708527
Age: postnatal adult
Specimen Label: Eif4e+/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5708525
Assay Type: Western blot
Annotation Date: 2016-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5708527
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5708525
Assay Type: Western blot
Annotation Date: 2016-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5708527
Age: postnatal adult
Specimen Label: Eif4e+/-
Detected: true
Specimen Num: 6
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Publication
31427534 | J:278826
First Author: Wiebe S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Inhibitory interneurons mediate autism-associated behaviors via 4E-BP2.
Volume: 116
Issue: 36
Pages: 18060-18067
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Publication
36170669 | J:332823
First Author: Miller WP
Year: 2022
Journal: Diabetes
Title: Activation of Disulfide Redox Switch in REDD1 Promotes Oxidative Stress Under Hyperglycemic Conditions.
Volume: 71
Issue: 12
Pages: 2764-2776
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Publication
17273556 | J:118038
First Author: Le Bacquer O
Year: 2007
Journal: J Clin Invest
Title: Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2.
Volume: 117
Issue: 2
Pages: 387-96
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Publication
19175792 | J:243830
First Author: Olson KE
Year: 2009
Journal: Immunology
Title: Impaired myelopoiesis in mice lacking the repressors of translation initiation, 4E-BP1 and 4E-BP2.
Volume: 128
Issue: 1 Suppl
Pages: e376-84
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Publication
26998719 | J:254615
First Author: Miller WP
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: The Translational Repressor 4E-BP1 Contributes to Diabetes-Induced Visual Dysfunction.
Volume: 57
Issue: 3
Pages: 1327-37
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Publication
30894372 | J:274187
First Author: Wang Z
Year: 2019
Journal: Cancer Res
Title: 4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer.
Volume: 79
Issue: 7
Pages: 1438-1450
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Publication
30927336 | J:295227
First Author: Le Bacquer O
Year: 2019
Journal: J Cachexia Sarcopenia Muscle
Title: 4E-BP1 and 4E-BP2 double knockout mice are protected from aging-associated sarcopenia.
Volume: 10
Issue: 3
Pages: 696-709
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Publication
19843855 | J:153953
First Author: Kim YY
Year: 2009
Journal: Cancer Res
Title: Eukaryotic initiation factor 4E binding protein family of proteins: sentinels at a translational control checkpoint in lung tumor defense.
Volume: 69
Issue: 21
Pages: 8455-62
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Publication
23434932 | J:208544
First Author: Dennis MD
Year: 2013
Journal: Diabetes
Title: Hyperglycemia mediates a shift from cap-dependent to cap-independent translation via a 4E-BP1-dependent mechanism.
Volume: 62
Issue: 7
Pages: 2204-14
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Publication
35675781 | J:326145
First Author: Saviuk N
Year: 2022
Journal: Cell Rep
Title: Loss of 4E-BP converts cerebellar long-term depression to long-term potentiation.
Volume: 39
Issue: 10
Pages: 110911
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Publication
27492367 | J:235616
First Author: Signer RA
Year: 2016
Journal: Genes Dev
Title: The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs.
Volume: 30
Issue: 15
Pages: 1698-703
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Publication
30733333 | J:280102
First Author: Dierschke SK
Year: 2019
Journal: J Biol Chem
Title: O-GlcNAcylation alters the selection of mRNAs for translation and promotes 4E-BP1-dependent mitochondrial dysfunction in the retina.
Volume: 294
Issue: 14
Pages: 5508-5520
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Publication
24945486 | J:216832
First Author: Steiner JL
Year: 2014
Journal: PLoS One
Title: Disruption of genes encoding eIF4E binding proteins-1 and -2 does not alter basal or sepsis-induced changes in skeletal muscle protein synthesis in male or female mice.
Volume: 9
Issue: 6
Pages: e99582
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Publication
31825840 | J:296924
First Author: Kouloulia S
Year: 2019
Journal: Cell Rep
Title: Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity.
Volume: 29
Issue: 11
Pages: 3620-3635.e7
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Publication
20347422 | J:162956
First Author: Bidinosti M
Year: 2010
Journal: Mol Cell
Title: Postnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmission.
Volume: 37
Issue: 6
Pages: 797-808
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Publication
9464245 | J:47955
First Author: Zhou J
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast.
Volume: 242
Issue: 3
Pages: 502-7
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Publication
20547975 | J:169349
First Author: Schrufer TL
Year: 2010
Journal: Diabetes
Title: Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Muller cells in culture.
Volume: 59
Issue: 9
Pages: 2107-16
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Publication
29617653 | J:271198
First Author: Chong Y
Year: 2018
Journal: Cell Rep
Title: Removing 4E-BP Enables Synapses to Refine without Postsynaptic Activity.
Volume: 23
Issue: 1
Pages: 11-22
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Publication
33328636 | J:306868
First Author: Aguilar-Valles A
Year: 2021
Journal: Nature
Title: Antidepressant actions of ketamine engage cell-specific translation via eIF4E.
Volume: 590
Issue: 7845
Pages: 315-319
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Publication
31032899 | J:281990
First Author: William M
Year: 2019
Journal: Eur J Immunol
Title: Translational repression of Ccl5 and Cxcl10 by 4E-BP1 and 4E-BP2 restrains the ability of mouse macrophages to induce migration of activated T cells.
Volume: 49
Issue: 8
Pages: 1200-1212
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Publication
31747684 | J:283731
First Author: Starr CR
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Role of Translational Attenuation in Inherited Retinal Degeneration.
Volume: 60
Issue: 14
Pages: 4849-4857
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Publication
20493810 | J:160601
First Author: Carnevalli LS
Year: 2010
Journal: Dev Cell
Title: S6K1 plays a critical role in early adipocyte differentiation.
Volume: 18
Issue: 5
Pages: 763-74
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Publication
29712774 | J:263333
First Author: William M
Year: 2018
Journal: J Immunol
Title: eIF4E-Binding Proteins 1 and 2 Limit Macrophage Anti-Inflammatory Responses through Translational Repression of IL-10 and Cyclooxygenase-2.
Volume: 200
Issue: 12
Pages: 4102-4116
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Publication
32475820 | J:332824
First Author: Dierschke SK
Year: 2020
Journal: J Biol Chem
Title: Diabetes enhances translation of Cd40 mRNA in murine retinal Müller glia via a 4E-BP1/2-dependent mechanism.
Volume: 295
Issue: 31
Pages: 10831-10841
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Publication
28699639 | J:250382
 
First Author: Blandino-Rosano M
Year: 2017
Journal: Nat Commun
Title: Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing.
Volume: 8
Pages: 16014
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Publication
18272964 | J:134222
First Author: Colina R
Year: 2008
Journal: Nature
Title: Translational control of the innate immune response through IRF-7.
Volume: 452
Issue: 7185
Pages: 323-8
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Publication
26678009 | J:228277
   
First Author: Khoutorsky A
Year: 2015
Journal: Elife
Title: Translational control of nociception via 4E-binding protein 1.
Volume: 4
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Publication
23658533 | J:197132
First Author: Bjur E
Year: 2013
Journal: PLoS Genet
Title: Distinct translational control in CD4+ T cell subsets.
Volume: 9
Issue: 5
Pages: e1003494
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Publication
23263185 | J:194400
First Author: Santini E
Year: 2013
Journal: Nature
Title: Exaggerated translation causes synaptic and behavioural aberrations associated with autism.
Volume: 493
Issue: 7432
Pages: 411-5
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Publication
8975712 | J:37710
First Author: Tsukiyama-Kohara K
Year: 1996
Journal: Genomics
Title: Tissue distribution, genomic structure, and chromosome mapping of mouse and human eukaryotic initiation factor 4E-binding proteins 1 and 2.
Volume: 38
Issue: 3
Pages: 353-63
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Publication
19244480 | J:149769
First Author: Sukarieh R
Year: 2009
Journal: Am J Physiol Cell Physiol
Title: The eIF4E-binding proteins are modifiers of cytoplasmic eIF4E relocalization during the heat shock response.
Volume: 296
Issue: 5
Pages: C1207-17
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Publication
23172145 | J:194221
First Author: Gkogkas CG
Year: 2013
Journal: Nature
Title: Autism-related deficits via dysregulated eIF4E-dependent translational control.
Volume: 493
Issue: 7432
Pages: 371-7
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Publication
19878875 | J:153944
First Author: Petroulakis E
Year: 2009
Journal: Cancer Cell
Title: p53-dependent translational control of senescence and transformation via 4E-BPs.
Volume: 16
Issue: 5
Pages: 439-46
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Publication
24206664 | J:206172
First Author: Morita M
Year: 2013
Journal: Cell Metab
Title: mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation.
Volume: 18
Issue: 5
Pages: 698-711
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Publication
27217487 | J:246863
First Author: Blandino-Rosano M
Year: 2016
Journal: Diabetes
Title: 4E-BP2/SH2B1/IRS2 Are Part of a Novel Feedback Loop That Controls β-Cell Mass.
Volume: 65
Issue: 8
Pages: 2235-48
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Publication
33876772 | J:304843
 
First Author: Sharma V
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: 4E-BP2-dependent translation in parvalbumin neurons controls epileptic seizure threshold.
Volume: 118
Issue: 15
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Publication
32213561 | J:288497
First Author: Pearl D
Year: 2020
Journal: J Immunol
Title: 4E-BP-Dependent Translational Control of Irf8 Mediates Adipose Tissue Macrophage Inflammatory Response.
Volume: 204
Issue: 9
Pages: 2392-2400
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Publication
29453322 | J:260731
First Author: Ding M
Year: 2018
Journal: Mol Cancer Res
Title: The mTOR Targets 4E-BP1/2 Restrain Tumor Growth and Promote Hypoxia Tolerance in PTEN-driven Prostate Cancer.
Volume: 16
Issue: 4
Pages: 682-695
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Publication
21501832 | J:273483
First Author: Jaramillo M
Year: 2011
Journal: Cell Host Microbe
Title: Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection.
Volume: 9
Issue: 4
Pages: 331-41
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Publication
17635924 | J:124932
First Author: Gelinas JN
Year: 2007
Journal: J Biol Chem
Title: ERK and mTOR signaling couple beta-adrenergic receptors to translation initiation machinery to gate induction of protein synthesis-dependent long-term potentiation.
Volume: 282
Issue: 37
Pages: 27527-35
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Publication
23818585 | J:198805
First Author: Shen C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: The mTOR pathway negatively controls ATM by up-regulating miRNAs.
Volume: 110
Issue: 29
Pages: 11869-74
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Publication
25872869 | J:260549
First Author: Chung J
Year: 2015
Journal: Sci Signal
Title: The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability.
Volume: 8
Issue: 372
Pages: ra34
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Publication
8939971 | J:51748
First Author: Lin TA
Year: 1996
Journal: J Biol Chem
Title: Control of the translational regulators PHAS-I and PHAS-II by insulin and cAMP in 3T3-L1 adipocytes.
Volume: 271
Issue: 47
Pages: 30199-204
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Publication
23184952 | J:244821
First Author: Dennis MD
Year: 2013
Journal: J Biol Chem
Title: Mechanistic target of rapamycin complex 1 (mTORC1)-mediated phosphorylation is governed by competition between substrates for interaction with raptor.
Volume: 288
Issue: 1
Pages: 10-9
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Publication
26095252 | J:224214
First Author: Truitt ML
Year: 2015
Journal: Cell
Title: Differential Requirements for eIF4E Dose in Normal Development and Cancer.
Volume: 162
Issue: 1
Pages: 59-71
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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