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Search results 1 to 100 out of 102 for Exog

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Categories

Hits by Pathway

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Hits by Strain

Type Details Score
Gene
9941 | EXOG
Type: gene
Organism: human
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Gene
100486077 | exog
Type: gene
Organism: frog, western clawed
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Gene
141380777 | exog
Type: gene
Organism: zebrafish
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Gene
301062 | Exog
Type: gene
Organism: rat
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Gene
485591 | EXOG
Type: gene
Organism: dog, domestic
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Gene
747482 | EXOG
Type: gene
Organism: chimpanzee
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Gene
524343 | EXOG
Type: gene
Organism: cattle
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Gene
420430 | EXOG
Type: gene
Organism: chicken
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Gene
695307 | EXOG
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2143333 | Exog
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100128324 | EXOGP1
Type: gene
Organism: human
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Protein Coding Gene
MGP_CAROLIEiJ_G0032802 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
ENSMUSG00200030150 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00195026945 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00220019182 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00180029195 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00175018637 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2143333 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00215029350 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSTCUG00005015923 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00210040042 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00185015942 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00205028773 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00230036260 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSUMUG00000024557 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00190013156 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00225023012 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSLUMG00010032163 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSIUOG00005019989 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015669 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
ENSMSPG00010019363 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:8436405
Assay Type: RT-PCR
Annotation Date: 2026-09-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1668828
Stage: TS28
Assay Id: MGI:8436409
Age: postnatal
Image: S7
Specimen Label: Control
Detected: true
Specimen Num: 1
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Publication
25378300 | J:218220
First Author: Szczesny B
Year: 2014
Journal: Nucleic Acids Res
Title: Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function.
Volume: 42
Issue: 21
Pages: 13161-73
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Publication
31666509 | J:281596
First Author: Man JCK
Year: 2019
Journal: Nat Commun
Title: An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo.
Volume: 10
Issue: 1
Pages: 4943
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Publication
22706305 | J:190769
First Author: van den Boogaard M
Year: 2012
Journal: J Clin Invest
Title: Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.
Volume: 122
Issue: 7
Pages: 2519-30
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:389486
     
First Author: Mouse Genome Informatics and Ensembl Genome Database Project
Year: 2026
Journal: Database Release
Title: MGI Strain Genome Feature and Gene Model Load from Ensembl.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
2050634 | -
First Author: Reed JW
Year: 1991
Journal: J Bacteriol
Title: Rhizobium meliloti exoG and exoJ mutations affect the exoX-exoY system for modulation of exopolysaccharide production.
Volume: 173
Issue: 12
Pages: 3776-88
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Allele
Del(9Rr207838-Rr207840)6Vmc | MGI:7423612
Name: deletion, Chr 9, Vincent M Christoffels 6
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr207840<em1Vmc> | MGI:7423615
Name: regulatory region 207840; endonuclease-mediated mutation 1, Vincent M Christoffels
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Del(9Rr207838-Rr207840)8Vmc | MGI:7423616
Name: deletion, Chr 9, Vincent M Christoffels 8
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr207838<em1Vmc> | MGI:7423618
Name: regulatory region 207838; endonuclease-mediated mutation 1, Vincent M Christoffels
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Strain
MGI:7425193 | FVB/NRj-Del(9Rr207838-Rr207840)6Vmc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Del(9Rr207839-Rr207840)9Vmc | MGI:7423617
Name: deletion, Chr 9, Vincent M Christoffels 9
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Genotype
Genotype
Symbol: Del(9Rr207838-Rr207840)6Vmc/+
Background: FVB/NRj-Del(9Rr207838-Rr207840)6Vmc
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(9Rr207838-Rr207840)6Vmc/Del(9Rr207838-Rr207840)6Vmc
Background: FVB/NRj-Del(9Rr207838-Rr207840)6Vmc
Zygosity: hm
Has Mutant Allele: true
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Publication
11004006 | -
First Author: Johnson KA
Year: 2000
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Osteoblast tissue-nonspecific alkaline phosphatase antagonizes and regulates PC-1.
Volume: 279
Issue: 4
Pages: R1365-77
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Publication
26371182 | -
First Author: Stein AJ
Year: 2015
Journal: Mol Pharmacol
Title: Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
Volume: 88
Issue: 6
Pages: 982-92
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Publication
27467858 | -
First Author: Stella J
Year: 2016
Journal: Hum Mutat
Title: Effects of Different Variants in the ENPP1 Gene on the Functional Properties of Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 1.
Volume: 37
Issue: 11
Pages: 1190-1201
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Publication
27754931 | -
First Author: Bain G
Year: 2017
Journal: J Pharmacol Exp Ther
Title: Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis.
Volume: 360
Issue: 1
Pages: 1-13
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Protein Domain
IPR020821 | ENPP1-3/EXOG-like_nuc-like
Type: Domain
Description: A family of bacterial and eukaryotic endonucleases share the following characteristics: they act on both DNA and RNA, cleave double-stranded and single-stranded nucleic acids and require a divalent ion such as magnesium for their activity. A histidine has been shown []to be essential for the activity of the Serratia marcescens nuclease. This residue is located in a conserved region which also contains an aspartic acid residue that could be implicated in the binding of the divalent ion.This entry represents the nuclease/phosphodiesterase domain found in proteins from bacteria and eukaryotes, including ENPP1-3, mitochondrial Endonuclease G and Nuclease EXOG from animals, venom phosphodiesterases and related proteins.ENPP1 is a nucleotide pyrophosphatase that generates diphosphate (PPi) and functions in bone mineralization and soft tissue calcification by regulating pyrophosphate levels []. It preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP and UTP to their corresponding monophosphates with release of pyrophosphate, as well as diadenosine polyphosphates, and also 3',5'-cAMP to AMP [, , , ]. ENPP2, also known as autotaxin, is a secreted lysophospholipase D that hydrolyzes lysophospholipids to produce the signaling molecule lysophosphatidic acid (LPA) in extracellular fluids [, ]. ENPP3 metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP [].Endonuclease G and EXOG act on DNA, preferentially double-stranded 5-hydroxymethylcytosine (5hmC)-modified DNA []and supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity [], respectively.
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Publication
18187503 | -
First Author: Cymerman IA
Year: 2008
Journal: Nucleic Acids Res
Title: EXOG, a novel paralog of Endonuclease G in higher eukaryotes.
Volume: 36
Issue: 4
Pages: 1369-79
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Publication
25355512 | J:218272
First Author: Robertson AB
Year: 2014
Journal: Nucleic Acids Res
Title: Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination.
Volume: 42
Issue: 21
Pages: 13280-93
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Publication
25344812 | J:273512
First Author: Li L
Year: 2014
Journal: Nat Chem Biol
Title: Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs.
Volume: 10
Issue: 12
Pages: 1043-8
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Publication
35147247 | -
First Author: Szeri F
Year: 2022
Journal: J Bone Miner Res
Title: The Mineralization Regulator ANKH Mediates Cellular Efflux of ATP, Not Pyrophosphate.
Volume: 37
Issue: 5
Pages: 1024-1031
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Publication
28011303 | -
First Author: Namasivayam V
Year: 2017
Journal: Biochim Biophys Acta Gen Subj
Title: The promiscuous ectonucleotidase NPP1: molecular insights into substrate binding and hydrolysis.
Volume: 1861
Issue: 3
Pages: 603-614
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Publication
29717535 | -
First Author: Gorelik A
Year: 2018
Journal: FEBS J
Title: Structural basis for nucleotide recognition by the ectoenzyme CD203c.
Volume: 285
Issue: 13
Pages: 2481-2494
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Protein
Q8C522
Organism: Mus musculus/domesticus
Length: 501  
Fragment?: false
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Protein
Q69ZY2
Organism: Mus musculus/domesticus
Length: 591  
Fragment?: true
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Publication
8078761 | -
First Author: Friedhoff P
Year: 1994
Journal: Nucleic Acids Res
Title: Identification of catalytically relevant amino acids of the extracellular Serratia marcescens endonuclease by alignment-guided mutagenesis.
Volume: 22
Issue: 16
Pages: 3280-7
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Protein
O08600
Organism: Mus musculus/domesticus
Length: 294  
Fragment?: false
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Protein
Q8C163
Organism: Mus musculus/domesticus
Length: 368  
Fragment?: false
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Protein
Q3UN47
Organism: Mus musculus/domesticus
Length: 294  
Fragment?: false
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Protein
Q3V3C8
Organism: Mus musculus/domesticus
Length: 695  
Fragment?: true
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Protein
Q4FZF8
Organism: Mus musculus/domesticus
Length: 442  
Fragment?: true
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Protein
Q99K07
Organism: Mus musculus/domesticus
Length: 565  
Fragment?: true
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Protein
Q6DYE8
Organism: Mus musculus/domesticus
Length: 874  
Fragment?: false
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Protein
P06802
Organism: Mus musculus/domesticus
Length: 906  
Fragment?: false
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Protein
Q9R1E6
Organism: Mus musculus/domesticus
Length: 862  
Fragment?: false
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Protein
A0A0R4J1Q7
Organism: Mus musculus/domesticus
Length: 906  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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