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Search results 1 to 100 out of 1038 for Foxc1

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Hits by Strain

Type Details Score
Gene
2296 | FOXC1
Type: gene
Organism: human
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Gene
493250 | foxc1
Type: gene
Organism: frog, western clawed
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Gene
112443733 | FOXC1
Type: gene
Organism: cattle
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Gene
119867598 | FOXC1
Type: gene
Organism: dog, domestic
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Gene
750577 | FOXC1
Type: gene
Organism: chimpanzee
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Gene
364706 | Foxc1
Type: gene
Organism: rat
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Gene
395856 | FOXC1
Type: gene
Organism: chicken
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Gene
722918 | FOXC1
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR033067 | FoxC1
Type: Family
Description: Forkhead box (Fox) proteins are a family of transcription factors characterised by the presence of a 'forkhead' or winged-helix DNA-binding domain. This entry represents Forkhead box protein C1 (FOXC1, also known as Fkhl-7) which, in humans, participates in a broad range of developmental processes including somatic, cardiovascular, kidney, eye, skull and cortical development [].
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Protein Coding Gene
MGI:1347466 | Foxc1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
19668217 | J:152710
First Author: Aldinger KA
Year: 2009
Journal: Nat Genet
Title: FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation.
Volume: 41
Issue: 9
Pages: 1037-42
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Gene
101927703 | FOXCUT
Type: gene
Organism: human
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Protein
Q61572
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: false
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Publication
26912704 | J:229528
First Author: Wang L
Year: 2016
Journal: Science
Title: Foxc1 reinforces quiescence in self-renewing hair follicle stem cells.
Volume: 351
Issue: 6273
Pages: 613-7
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Publication
25513817 | J:266747
   
First Author: Haldipur P
Year: 2014
Journal: Elife
Title: Foxc1 dependent mesenchymal signalling drives embryonic cerebellar growth.
Volume: 3
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Publication
22522965 | J:188816
First Author: Sasman A
Year: 2012
Journal: Genesis
Title: Generation of conditional alleles for Foxc1 and Foxc2 in mice.
Volume: 50
Issue: 10
Pages: 766-74
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Publication
28223138 | J:240396
First Author: Motojima M
Year: 2017
Journal: Exp Cell Res
Title: Foxc1 and Foxc2 are necessary to maintain glomerular podocytes.
Volume: 352
Issue: 2
Pages: 265-272
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Publication
23862012 | J:199438
First Author: Siegenthaler JA
Year: 2013
Journal: Biol Open
Title: Foxc1 is required by pericytes during fetal brain angiogenesis.
Volume: 2
Issue: 7
Pages: 647-59
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Publication
25808752 | J:221866
 
First Author: Yoshida M
Year: 2015
Journal: Nat Commun
Title: The transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossification.
Volume: 6
Pages: 6653
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Publication
37154714 | J:337938
First Author: Tan C
Year: 2023
Journal: EMBO Rep
Title: Endothelial FOXC1 and FOXC2 promote intestinal regeneration after ischemia-reperfusion injury.
Volume: 24
Issue: 7
Pages: e56030
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Publication
25733312 | J:221192
First Author: Prasitsak T
Year: 2015
Journal: Dev Dyn
Title: Foxc1 is required for early stage telencephalic vascular development.
Volume: 244
Issue: 5
Pages: 703-11
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Publication
31588228 | J:297206
First Author: Lee YH
Year: 2019
Journal: Theranostics
Title: Role of FOXC1 in regulating APSCs self-renewal via STI-1/PrPC signaling.
Volume: 9
Issue: 22
Pages: 6443-6465
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Publication
38580085 | J:352624
First Author: Wei W
Year: 2024
Journal: Genomics
Title: Variants in FOXC1 and FOXC2 identified in patients with conotruncal heart defects.
Volume: 116
Issue: 3
Pages: 110840
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Publication
29070831 | J:255407
First Author: Gao B
Year: 2017
Journal: Sci Rep
Title: Inhibition of lobuloalveolar development by FOXC1 overexpression in the mouse mammary gland.
Volume: 7
Issue: 1
Pages: 14017
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Publication
24590069 | J:210256
First Author: Omatsu Y
Year: 2014
Journal: Nature
Title: Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation.
Volume: 508
Issue: 7497
Pages: 536-40
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Publication
14512019 | J:85739
First Author: Rice R
Year: 2003
Journal: Dev Biol
Title: Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4.
Volume: 262
Issue: 1
Pages: 75-87
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Publication
27592801 | J:238355
First Author: Cui CY
Year: 2017
Journal: J Invest Dermatol
Title: Foxc1 Ablated Mice Are Anhidrotic and Recapitulate Features of Human Miliaria Sweat Retention Disorder.
Volume: 137
Issue: 1
Pages: 38-45
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Publication
32510325 | J:290955
   
First Author: Norden PR
Year: 2020
Journal: Elife
Title: Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation.
Volume: 9
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Publication
22022403 | J:178103
First Author: McKeone R
Year: 2011
Journal: PLoS One
Title: Foxf2: a novel locus for anterior segment dysgenesis adjacent to the Foxc1 gene.
Volume: 6
Issue: 10
Pages: e25489
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Publication
10767326 | J:61775
First Author: Smith RS
Year: 2000
Journal: Hum Mol Genet
Title: Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development.
Volume: 9
Issue: 7
Pages: 1021-32
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GXD Expression
GXD Expression
     
Probe: MGI:6173038
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190302
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Foxc1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6173038
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190302
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Foxc1
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6173038
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190302
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Foxc1
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6173038
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190302
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Foxc1
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6173038
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190302
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Foxc1
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6173038
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190302
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Foxc1
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6173038
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190302
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Foxc1
Detected: false
Specimen Num: 6
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Publication
15196959 | J:91443
First Author: Wilm B
Year: 2004
Journal: Dev Biol
Title: The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus intermediate mesoderm cell fate.
Volume: 271
Issue: 1
Pages: 176-89
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Publication
29322554 | J:264474
First Author: Mya N
Year: 2018
Journal: Congenit Anom (Kyoto)
Title: Transcription factor Foxc1 is involved in anterior part of cranial base formation.
Volume: 58
Issue: 5
Pages: 158-166
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Publication
15906377 | J:98808
First Author: Rice R
Year: 2005
Journal: Dev Dyn
Title: Foxc1 integrates Fgf and Bmp signalling independently of twist or noggin during calvarial bone development.
Volume: 233
Issue: 3
Pages: 847-52
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Publication
32259372 | J:302064
First Author: Sanchez J
Year: 2020
Journal: Genesis
Title: Conditional inactivation of Foxc1 and Foxc2 in neural crest cells leads to cardiac abnormalities.
Volume: 58
Issue: 7
Pages: e23364
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Publication
18422524 | J:137357
First Author: Vivatbutsiri P
Year: 2008
Journal: J Anat
Title: Impaired meningeal development in association with apical expansion of calvarial bone osteogenesis in the Foxc1 mutant.
Volume: 212
Issue: 5
Pages: 603-11
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Publication
27214551 | J:237068
First Author: Fatima A
Year: 2016
Journal: J Clin Invest
Title: Foxc1 and Foxc2 deletion causes abnormal lymphangiogenesis and correlates with ERK hyperactivation.
Volume: 126
Issue: 7
Pages: 2437-51
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Publication
23677979 | J:202056
First Author: Sizemore GM
Year: 2013
Journal: Biol Reprod
Title: FOXC1 is enriched in the mammary luminal progenitor population, but is not necessary for mouse mammary ductal morphogenesis.
Volume: 89
Issue: 1
Pages: 10
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Publication
11782474 | J:75459
First Author: Berry FB
Year: 2002
Journal: J Biol Chem
Title: FOXC1 transcriptional regulation is mediated by N- and C-terminal activation domains and contains a phosphorylated transcriptional inhibitory domain.
Volume: 277
Issue: 12
Pages: 10292-7
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Publication
28253399 | J:254700
First Author: Seo S
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Foxc1 and Foxc2 in the Neural Crest Are Required for Ocular Anterior Segment Development.
Volume: 58
Issue: 3
Pages: 1368-1377
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Publication
16412416 | J:105944
First Author: Mattiske D
Year: 2006
Journal: Dev Biol
Title: The mouse forkhead gene Foxc1 is required for primordial germ cell migration and antral follicle development.
Volume: 290
Issue: 2
Pages: 447-58
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Publication
34331943 | J:310856
First Author: Almubarak A
Year: 2021
Journal: J Biol Chem
Title: Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification.
Volume: 297
Issue: 3
Pages: 101020
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Publication
22171010 | J:181974
First Author: Seo S
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth.
Volume: 109
Issue: 6
Pages: 2015-20
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Publication
24385915 | J:223126
First Author: Inman KE
Year: 2013
Journal: PLoS Genet
Title: Interaction between Foxc1 and Fgf8 during mammalian jaw patterning and in the pathogenesis of syngnathia.
Volume: 9
Issue: 12
Pages: e1003949
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Publication
16839542 | J:119303
First Author: Seo S
Year: 2006
Journal: Dev Biol
Title: Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract.
Volume: 296
Issue: 2
Pages: 421-36
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Publication
39012257 | J:353623
 
First Author: Almubarak A
Year: 2024
Journal: Development
Title: FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton.
Volume: 151
Issue: 16
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Publication
24472616 | J:212049
First Author: Silla ZT
Year: 2014
Journal: Exp Cell Res
Title: Signals from the lens and Foxc1 regulate the expression of key genes during the onset of corneal endothelial development.
Volume: 322
Issue: 2
Pages: 381-8
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Publication
23344708 | J:194058
First Author: Sun J
Year: 2013
Journal: Development
Title: Foxc1 controls the growth of the murine frontal bone rudiment by direct regulation of a Bmp response threshold of Msx2.
Volume: 140
Issue: 5
Pages: 1034-44
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Publication
11562355 | J:71693
First Author: Kume T
Year: 2001
Journal: Genes Dev
Title: The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis.
Volume: 15
Issue: 18
Pages: 2470-82
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Publication
27671872 | J:237944
First Author: Mishra S
Year: 2016
Journal: Dev Biol
Title: Cerebrovascular defects in Foxc1 mutants correlate with aberrant WNT and VEGF-A pathways downstream of retinoic acid from the meninges.
Volume: 420
Issue: 1
Pages: 148-165
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Publication
16678147 | J:119144
First Author: Seo S
Year: 2006
Journal: Dev Biol
Title: The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development.
Volume: 294
Issue: 2
Pages: 458-70
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Publication
10704385 | J:60834
First Author: Kume T
Year: 2000
Journal: Development
Title: Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract.
Volume: 127
Issue: 7
Pages: 1387-95
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GXD Expression
GXD Expression
Probe: MGI:7261257
Assay Type: Immunohistochemistry
Annotation Date: 2022-04-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7261300
Age: embryonic day 12.5
Image: 6C
Note: Co-localization with Foxc1 in cartilage areas of cranial base.
Specimen Label: 6C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7261257
Assay Type: Immunohistochemistry
Annotation Date: 2022-04-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7261300
Age: embryonic day 12.5
Image: 6G/H
Note: Co-localization with Foxc1 in cartilage areas of cranial base.
Specimen Label: 6G/H
Detected: true
Specimen Num: 2
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Publication
17715063 | J:136459
First Author: Zarbalis K
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Cortical dysplasia and skull defects in mice with a Foxc1 allele reveal the role of meningeal differentiation in regulating cortical development.
Volume: 104
Issue: 35
Pages: 14002-7
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Publication
28092268 | J:253288
   
First Author: Haldipur P
Year: 2017
Journal: Elife
Title: Phenotypic outcomes in Mouse and Human Foxc1 dependent Dandy-Walker cerebellar malformation suggest shared mechanisms.
Volume: 6
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Publication
11179011 | J:67859
First Author: Saleem RA
Year: 2001
Journal: Am J Hum Genet
Title: Analyses of the effects that disease-causing missense mutations have on the structure and function of the winged-helix protein FOXC1.
Volume: 68
Issue: 3
Pages: 627-41
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Publication
11165495 | J:67310
First Author: Topczewska JM
Year: 2001
Journal: Mech Dev
Title: Sequence and expression of zebrafish foxc1a and foxc1b, encoding conserved forkhead/winged helix transcription factors.
Volume: 100
Issue: 2
Pages: 343-7
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Publication
18187037 | J:131323
First Author: Hayashi H
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Forkhead transcription factors regulate expression of the chemokine receptor CXCR4 in endothelial cells and CXCL12-induced cell migration.
Volume: 367
Issue: 3
Pages: 584-9
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Publication
12624268 | J:82280
First Author: Libby RT
Year: 2003
Journal: Science
Title: Modification of ocular defects in mouse developmental glaucoma models by tyrosinase.
Volume: 299
Issue: 5612
Pages: 1578-81
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Publication
16470615 | J:107208
First Author: Mattiske D
Year: 2006
Journal: Dev Dyn
Title: The role of the forkhead transcription factor, Foxc1, in the development of the mouse lacrimal gland.
Volume: 235
Issue: 4
Pages: 1074-80
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Publication
29959321 | J:266245
First Author: Hirukawa A
Year: 2018
Journal: Nat Commun
Title: Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program.
Volume: 9
Issue: 1
Pages: 2547
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Publication
30943405 | J:291738
First Author: Adane B
Year: 2019
Journal: Cell Rep
Title: The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells.
Volume: 27
Issue: 1
Pages: 238-254.e6
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Publication
23145080 | J:195028
First Author: Mirzayans F
Year: 2012
Journal: PLoS One
Title: Initiation of early osteoblast differentiation events through the direct transcriptional regulation of Msx2 by FOXC1.
Volume: 7
Issue: 11
Pages: e49095
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Publication
15465483 | J:93150
First Author: Dagenais SL
Year: 2004
Journal: Gene Expr Patterns
Title: Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome.
Volume: 4
Issue: 6
Pages: 611-9
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Publication
19879845 | J:157301
First Author: Siegenthaler JA
Year: 2009
Journal: Cell
Title: Retinoic acid from the meninges regulates cortical neuron generation.
Volume: 139
Issue: 3
Pages: 597-609
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Publication
16207763 | J:102847
First Author: Matt N
Year: 2005
Journal: Development
Title: Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells.
Volume: 132
Issue: 21
Pages: 4789-800
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Publication
12015277 | J:76673
First Author: Lines MA
Year: 2002
Journal: Hum Mol Genet
Title: Molecular genetics of Axenfeld-Rieger malformations.
Volume: 11
Issue: 10
Pages: 1177-84
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Publication
18545664 | J:137147
First Author: Hayashi H
Year: 2008
Journal: PLoS One
Title: Foxc transcription factors directly regulate Dll4 and Hey2 expression by interacting with the VEGF-Notch signaling pathways in endothelial cells.
Volume: 3
Issue: 6
Pages: e2401
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Publication
16759280 | J:356614
First Author: Sommer P
Year: 2006
Journal: Dev Growth Differ
Title: Identification of Tgf beta1i4 as a downstream target of Foxc1.
Volume: 48
Issue: 5
Pages: 297-308
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Publication
31845891 | J:291752
   
First Author: Portal C
Year: 2019
Journal: Elife
Title: Primary cilia deficiency in neural crest cells models anterior segment dysgenesis in mouse.
Volume: 8
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Publication
39217245 | J:353558
First Author: Havrylov S
Year: 2024
Journal: Sci Rep
Title: Pleiotropy in FOXC1-attributable phenotypes involves altered ciliation and cilia-dependent signaling.
Volume: 14
Issue: 1
Pages: 20278
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Publication
24417671 | J:213450
First Author: Machida A
Year: 2014
Journal: Congenit Anom (Kyoto)
Title: Difference in apical and basal growth of the frontal bone primordium in Foxc1ch/ch mice.
Volume: 54
Issue: 3
Pages: 172-7
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Publication
26718006 | J:229010
First Author: Wang J
Year: 2016
Journal: Development
Title: Yap and Taz play a crucial role in neural crest-derived craniofacial development.
Volume: 143
Issue: 3
Pages: 504-15
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Publication
22248045 | J:181175
 
First Author: Zarbalis K
Year: 2012
Journal: Neural Dev
Title: Meningeal defects alter the tangential migration of cortical interneurons in Foxc1hith/hith mice.
Volume: 7
Pages: 2
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Publication
16459152 | J:109569
First Author: Mitchell EK
Year: 2006
Journal: Gene Expr Patterns
Title: Differential gene expression in the developing mouse ureter.
Volume: 6
Issue: 5
Pages: 519-38
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Publication
20976766 | J:250521
First Author: Hecht JH
Year: 2010
Journal: Ann Neurol
Title: Primary cellular meningeal defects cause neocortical dysplasia and dyslamination.
Volume: 68
Issue: 4
Pages: 454-64
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Publication
26839363 | J:240081
First Author: Mayeuf-Louchart A
Year: 2016
Journal: Development
Title: Endothelial cell specification in the somite is compromised in Pax3-positive progenitors of Foxc1/2 conditional mutants, with loss of forelimb myogenesis.
Volume: 143
Issue: 5
Pages: 872-9
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Publication
33898467 | J:306327
 
First Author: Xu J
Year: 2021
Journal: Front Cell Dev Biol
Title: Cis-Repression of Foxq1 Expression Affects Foxf2-Mediated Gene Expression in Palate Development.
Volume: 9
Pages: 665109
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Publication
19369394 | J:148019
First Author: Huang J
Year: 2009
Journal: Development
Title: FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate.
Volume: 136
Issue: 10
Pages: 1741-50
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Publication
24055172 | J:203791
First Author: Kuracha MR
Year: 2013
Journal: Dev Biol
Title: Spry1 and Spry2 are necessary for eyelid closure.
Volume: 383
Issue: 2
Pages: 227-38
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Protein Coding Gene
MGP_CAROLIEiJ_G0018400 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020423 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020378 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020355 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020373 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020176 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1347466 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020809 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019693 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020132 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020254 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020239 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020331 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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