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Search results 1 to 100 out of 228 for Irgm1

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Type Details Score
Protein
A0A1G5SJJ3
Organism: Mus musculus/domesticus
Length: 409  
Fragment?: false
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Protein Coding Gene
MGI:107567 | Irgm1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
33510463 | J:305209
First Author: Rai P
Year: 2021
Journal: Nat Immunol
Title: IRGM1 links mitochondrial quality control to autoimmunity.
Volume: 22
Issue: 3
Pages: 312-321
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Publication
32311672 | J:303514
 
First Author: Zhang L
Year: 2020
Journal: Int Immunopharmacol
Title: Irgm1 knockout indirectly inhibits regeneration after skeletal muscle injury in mice.
Volume: 84
Pages: 106515
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Publication
17982087 | J:153857
First Author: Henry SC
Year: 2007
Journal: J Immunol
Title: Impaired macrophage function underscores susceptibility to Salmonella in mice lacking Irgm1 (LRG-47).
Volume: 179
Issue: 10
Pages: 6963-72
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Publication
21633090 | J:176943
First Author: King KY
Year: 2011
Journal: Blood
Title: Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling.
Volume: 118
Issue: 6
Pages: 1525-33
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Publication
27439214 | J:318620
 
First Author: Fang S
Year: 2016
Journal: Atherosclerosis
Title: Irgm1 promotes M1 but not M2 macrophage polarization in atherosclerosis pathogenesis and development.
Volume: 251
Pages: 282-290
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Publication
23689639 | J:207253
 
First Author: Xia F
Year: 2013
Journal: Sci Rep
Title: IRGM1 regulates oxidized LDL uptake by macrophage via actin-dependent receptor internalization during atherosclerosis.
Volume: 3
Pages: 1867
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Publication
20072621 | J:157238
First Author: Zhao YO
Year: 2010
Journal: PLoS One
Title: Localisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cells.
Volume: 5
Issue: 1
Pages: e8648
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Publication
35197566 | J:328106
First Author: Fan Y
Year: 2022
Journal: Cell Death Differ
Title: Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis.
Volume: 29
Issue: 9
Pages: 1673-1688
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Publication
27443879 | J:243244
First Author: Xu Y
Year: 2017
Journal: J Leukoc Biol
Title: Irgm1 is required for the inflammatory function of M1 macrophage in early experimental autoimmune encephalomyelitis.
Volume: 101
Issue: 2
Pages: 507-517
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Publication
20056715 | J:162368
First Author: Xu H
Year: 2010
Journal: FASEB J
Title: Genetic deficiency of Irgm1 (LRG-47) suppresses induction of experimental autoimmune encephalomyelitis by promoting apoptosis of activated CD4+ T cells.
Volume: 24
Issue: 5
Pages: 1583-92
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Publication
18806793 | J:142840
First Author: Feng CG
Year: 2008
Journal: Nat Immunol
Title: The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death.
Volume: 9
Issue: 11
Pages: 1279-87
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Publication
19620982 | J:151541
First Author: Tiwari S
Year: 2009
Journal: Nat Immunol
Title: Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P(2) and PtdIns(3,4,5)P(3) promotes immunity to mycobacteria.
Volume: 10
Issue: 8
Pages: 907-17
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Publication
23842753 | J:205698
First Author: Springer HM
Year: 2013
Journal: J Immunol
Title: Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-γ-induced mouse cells.
Volume: 191
Issue: 4
Pages: 1765-74
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Publication
22796503 | J:188154
First Author: Wang C
Year: 2013
Journal: Mol Immunol
Title: Immune-related GTPase Irgm1 exacerbates experimental auto-immune encephalomyelitis by promoting the disruption of blood-brain barrier and blood-cerebrospinal fluid barrier.
Volume: 53
Issue: 1-2
Pages: 43-51
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Publication
16888103 | J:112322
First Author: Singh SB
Year: 2006
Journal: Science
Title: Human IRGM induces autophagy to eliminate intracellular mycobacteria.
Volume: 313
Issue: 5792
Pages: 1438-41
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Publication
23785284 | J:317923
First Author: Haldar AK
Year: 2013
Journal: PLoS Pathog
Title: IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins.
Volume: 9
Issue: 6
Pages: e1003414
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Publication
37874678 | J:342325
First Author: Chauhan NR
Year: 2023
Journal: Cell Rep
Title: Transgenic mouse models support a protective role of type I IFN response in SARS-CoV-2 infection-related lung immunopathology and neuroinvasion.
Volume: 42
Issue: 11
Pages: 113275
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Publication
36221902 | J:332005
First Author: Mehto S
Year: 2022
Journal: EMBO J
Title: Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection.
Volume: 41
Issue: 23
Pages: e111289
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Publication
22675202 | J:189560
First Author: Matsuzawa T
Year: 2012
Journal: J Immunol
Title: IFN-γ elicits macrophage autophagy via the p38 MAPK signaling pathway.
Volume: 189
Issue: 2
Pages: 813-8
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Publication
19920210 | J:157117
First Author: Henry SC
Year: 2010
Journal: J Leukoc Biol
Title: Regulation of macrophage motility by Irgm1.
Volume: 87
Issue: 2
Pages: 333-43
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Publication
22163006 | J:182269
First Author: Chang CP
Year: 2011
Journal: PLoS One
Title: Concanavalin A/IFN-gamma triggers autophagy-related necrotic hepatocyte death through IRGM1-mediated lysosomal membrane disruption.
Volume: 6
Issue: 12
Pages: e28323
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Publication
25644000 | J:229266
First Author: Guo J
Year: 2015
Journal: Infect Immun
Title: IRGM3 contributes to immunopathology and is required for differentiation of antigen-specific effector CD8+ T cells in experimental cerebral malaria.
Volume: 83
Issue: 4
Pages: 1406-17
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Publication
18424746 | J:134525
First Author: Coers J
Year: 2008
Journal: J Immunol
Title: Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10.
Volume: 180
Issue: 9
Pages: 6237-45
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Publication
33124745 | J:301384
First Author: Finethy R
Year: 2020
Journal: EMBO Rep
Title: Dynamin-related Irgm proteins modulate LPS-induced caspase-11 activation and septic shock.
Volume: 21
Issue: 11
Pages: e50830
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Publication
28154172 | J:241380
First Author: Schmidt EA
Year: 2017
Journal: J Biol Chem
Title: Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages.
Volume: 292
Issue: 11
Pages: 4651-4662
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Publication
19176402 | J:149702
First Author: Henry SC
Year: 2009
Journal: J Leukoc Biol
Title: Balance of Irgm protein activities determines IFN-gamma-induced host defense.
Volume: 85
Issue: 5
Pages: 877-85
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Publication
34338548 | J:333017
First Author: Dockterman J
Year: 2021
Journal: Infect Immun
Title: Murine Irgm Paralogs Regulate Nonredundant Functions To Execute Host Defense to Toxoplasma gondii.
Volume: 89
Issue: 11
Pages: e0020221
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Publication
23989005 | J:210568
First Author: Liu B
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation.
Volume: 305
Issue: 8
Pages: G573-84
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Publication
32453761 | J:292423
First Author: Taylor GA
Year: 2020
Journal: PLoS Pathog
Title: Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium.
Volume: 16
Issue: 5
Pages: e1008553
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Publication
22874556 | J:329066
First Author: He S
Year: 2012
Journal: Autophagy
Title: Immune-related GTPase M (IRGM1) regulates neuronal autophagy in a mouse model of stroke.
Volume: 8
Issue: 11
Pages: 1621-7
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Publication
34467632 | J:332983
First Author: Nath P
Year: 2021
Journal: EMBO Rep
Title: Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses.
Volume: 22
Issue: 11
Pages: e52948
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Publication
34078740 | J:308470
 
First Author: Pradipta A
Year: 2021
Journal: Life Sci Alliance
Title: Cell-autonomous Toxoplasma killing program requires Irgm2 but not its microbe vacuolar localization.
Volume: 4
Issue: 7
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Publication
21757726 | J:176619
First Author: Traver MK
Year: 2011
Journal: J Biol Chem
Title: Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy.
Volume: 286
Issue: 35
Pages: 30471-80
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Publication
31612615 | J:328983
First Author: Zhou RX
Year: 2020
Journal: CNS Neurosci Ther
Title: Regulation of hippocampal neuronal apoptosis and autophagy in mice with sepsis-associated encephalopathy by immunity-related GTPase M1.
Volume: 26
Issue: 2
Pages: 177-188
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Publication
36580725 | J:344483
 
First Author: Sun S
Year: 2023
Journal: Biomed Pharmacother
Title: IRGM/Irgm1 deficiency inhibits neutrophil-platelet interactions and thrombosis in experimental atherosclerosis and arterial injury.
Volume: 158
Pages: 114152
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Publication
29361512 | J:257085
     
First Author: Rogala AR
Year: 2017
Journal: Dis Model Mech
Title: Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice.
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Publication
24751652 | J:332984
First Author: Henry SC
Year: 2014
Journal: PLoS One
Title: Palmitoylation of the immunity related GTPase, Irgm1: impact on membrane localization and ability to promote mitochondrial fission.
Volume: 9
Issue: 4
Pages: e95021
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Publication
27098192 | J:332981
 
First Author: Maric-Biresev J
Year: 2016
Journal: BMC Biol
Title: Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection.
Volume: 14
Pages: 33
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Protein Coding Gene
MGP_CAROLIEiJ_G0016256 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018207 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018178 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018144 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018147 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017961 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_107567 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018601 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017524 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017933 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018043 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018037 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018115 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018061 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018640 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017304 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017574 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017392 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017097 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
19144319 | J:143718
First Author: Trost M
Year: 2009
Journal: Immunity
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
Volume: 30
Issue: 1
Pages: 143-54
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Publication
15294976 | J:92658
First Author: Martens S
Year: 2004
Journal: J Immunol
Title: Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis.
Volume: 173
Issue: 4
Pages: 2594-606
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Publication
18772884 | J:168299
First Author: Hunn JP
Year: 2008
Journal: EMBO J
Title: Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii.
Volume: 27
Issue: 19
Pages: 2495-509
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
7561525 | J:29047
First Author: Sorace JM
Year: 1995
Journal: J Leukoc Biol
Title: Identification of an endotoxin and IFN-inducible cDNA: possible identification of a novel protein family.
Volume: 58
Issue: 4
Pages: 477-84
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Publication
11457893 | J:87535
First Author: Collazo CM
Year: 2001
Journal: J Exp Med
Title: Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection.
Volume: 194
Issue: 2
Pages: 181-8
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Publication
14707092 | J:87364
First Author: Feng CG
Year: 2004
Journal: J Immunol
Title: Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia.
Volume: 172
Issue: 2
Pages: 1163-8
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Publication
15908352 | J:99144
First Author: Butcher BA
Year: 2005
Journal: Infect Immun
Title: p47 GTPases regulate Toxoplasma gondii survival in activated macrophages.
Volume: 73
Issue: 6
Pages: 3278-86
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Publication
16339555 | J:122278
First Author: Santiago HC
Year: 2005
Journal: J Immunol
Title: Mice deficient in LRG-47 display enhanced susceptibility to Trypanosoma cruzi infection associated with defective hemopoiesis and intracellular control of parasite growth.
Volume: 175
Issue: 12
Pages: 8165-72
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Publication
17911638 | J:153019
First Author: Bafica A
Year: 2007
Journal: J Immunol
Title: The IFN-inducible GTPase LRG47 (Irgm1) negatively regulates TLR4-triggered proinflammatory cytokine production and prevents endotoxemia.
Volume: 179
Issue: 8
Pages: 5514-22
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
21731484 | J:182190
First Author: Coers J
Year: 2011
Journal: PLoS Pathog
Title: Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections.
Volume: 7
Issue: 6
Pages: e1001346
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Publication
23853600 | J:213363
First Author: Berghout J
Year: 2013
Journal: PLoS Pathog
Title: Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria.
Volume: 9
Issue: 7
Pages: e1003491
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Publication
34694641 | J:333980
First Author: Christgen S
Year: 2022
Journal: Eur J Immunol
Title: The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice.
Volume: 52
Issue: 2
Pages: 285-296
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Publication
20566858 | J:162073
First Author: Dhar N
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Mycobacterium tuberculosis persistence mutants identified by screening in isoniazid-treated mice.
Volume: 107
Issue: 27
Pages: 12275-80
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Publication
21383050 | J:171938
First Author: von Bargen K
Year: 2011
Journal: Infect Immun
Title: Nitric oxide-mediated intracellular growth restriction of pathogenic Rhodococcus equi can be prevented by iron.
Volume: 79
Issue: 5
Pages: 2098-111
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
23070814 | J:188254
First Author: Budry L
Year: 2012
Journal: Genes Dev
Title: The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling.
Volume: 26
Issue: 20
Pages: 2299-310
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Publication
24715728 | J:208845
First Author: Pilla DM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.
Volume: 111
Issue: 16
Pages: 6046-51
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Publication
17082622 | J:140485
First Author: Koga R
Year: 2006
Journal: J Immunol
Title: TLR-dependent induction of IFN-beta mediates host defense against Trypanosoma cruzi.
Volume: 177
Issue: 10
Pages: 7059-66
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Publication
25482432 | J:268956
First Author: Sun L
Year: 2015
Journal: Cell Host Microbe
Title: Type I interferons link viral infection to enhanced epithelial turnover and repair.
Volume: 17
Issue: 1
Pages: 85-97
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Publication
28193861 | J:241213
First Author: Feeley EM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems.
Volume: 114
Issue: 9
Pages: E1698-E1706
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
22855710 | J:189851
First Author: Gondek DC
Year: 2012
Journal: J Immunol
Title: CD4+ T cells are necessary and sufficient to confer protection against Chlamydia trachomatis infection in the murine upper genital tract.
Volume: 189
Issue: 5
Pages: 2441-9
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Publication
31648279 | J:285422
First Author: Tuladhar S
Year: 2019
Journal: PLoS Pathog
Title: The ROP16III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival.
Volume: 15
Issue: 10
Pages: e1007856
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Publication
35941154 | J:327605
First Author: Chandrasekaran S
Year: 2022
Journal: Nat Commun
Title: IFN-γ stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii.
Volume: 13
Issue: 1
Pages: 4605
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Publication
38501887 | J:361381
First Author: Dockterman J
Year: 2024
Journal: mBio
Title: Irgm proteins attenuate inflammatory disease in mouse models of genital Chlamydia infection.
Volume: 15
Issue: 4
Pages: e0030324
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Publication
18371424 | J:149806
First Author: Feng CG
Year: 2008
Journal: Cell Stem Cell
Title: The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation.
Volume: 2
Issue: 1
Pages: 83-9
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Publication
23132496 | J:190883
First Author: Tischler AD
Year: 2013
Journal: Infect Immun
Title: Mycobacterium tuberculosis requires phosphate-responsive gene regulation to resist host immunity.
Volume: 81
Issue: 1
Pages: 317-28
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Publication
30612879 | J:271759
First Author: Mehto S
Year: 2019
Journal: Mol Cell
Title: The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy.
Volume: 73
Issue: 3
Pages: 429-445.e7
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Publication
32715615 | J:298776
First Author: Jena KK
Year: 2020
Journal: EMBO Rep
Title: Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS signaling to control interferon response.
Volume: 21
Issue: 9
Pages: e50051
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Publication
32542357 | J:301395
First Author: Norona J
Year: 2020
Journal: Blood
Title: Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans.
Volume: 136
Issue: 12
Pages: 1442-1455
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
25356593 | J:247338
First Author: Ferreira-da-Silva Mda F
Year: 2014
Journal: PLoS Pathog
Title: Identification of the microsporidian Encephalitozoon cuniculi as a new target of the IFNγ-inducible IRG resistance system.
Volume: 10
Issue: 10
Pages: e1004449
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Publication
23012479 | J:190322
First Author: Archambaud C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Impact of lactobacilli on orally acquired listeriosis.
Volume: 109
Issue: 41
Pages: 16684-9
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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