| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
Not Specified |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shen X |
| Year: |
2022 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Definition of a mouse microglial subset that regulates neuronal development and proinflammatory responses in the brain. |
| Volume: |
119 |
| Issue: |
8 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tzeng TC |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
CD11c(hi) dendritic cells regulate the re-establishment of vascular quiescence and stabilization after immune stimulation of lymph nodes. |
| Volume: |
184 |
| Issue: |
8 |
| Pages: |
4247-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Milam JE |
| Year: |
2010 |
| Journal: |
Am J Pathol |
| Title: |
CD11c+ cells are required to prevent progression from local acute lung injury to multiple organ failure and death. |
| Volume: |
176 |
| Issue: |
1 |
| Pages: |
218-26 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
304
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yashiro T |
| Year: |
2017 |
| Journal: |
Int Immunol |
| Title: |
The hematopoietic cell-specific transcription factor PU.1 is critical for expression of CD11c. |
| Volume: |
29 |
| Issue: |
2 |
| Pages: |
87-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhu XJ |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
PU.1 is essential for CD11c expression in CD8(+)/CD8(-) lymphoid and monocyte-derived dendritic cells during GM-CSF or FLT3L-induced differentiation. |
| Volume: |
7 |
| Issue: |
12 |
| Pages: |
e52141 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jones MB |
| Year: |
2016 |
| Journal: |
Glycobiology |
| Title: |
Dendritic cell-specific Mgat2 knockout mice show antigen presentation defects but reveal an unexpected CD11c expression pattern. |
| Volume: |
26 |
| Issue: |
9 |
| Pages: |
1007-1013 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Patsouris D |
| Year: |
2008 |
| Journal: |
Cell Metab |
| Title: |
Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. |
| Volume: |
8 |
| Issue: |
4 |
| Pages: |
301-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu J |
| Year: |
2023 |
| Journal: |
Cell Rep |
| Title: |
Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity. |
| Volume: |
42 |
| Issue: |
1 |
| Pages: |
111991 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okuyama M |
| Year: |
2010 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
A novel in vivo inducible dendritic cell ablation model in mice. |
| Volume: |
397 |
| Issue: |
3 |
| Pages: |
559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zeng M |
| Year: |
2016 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Mutagenetix entry for Adendritic |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hou L |
| Year: |
2022 |
| Journal: |
Front Immunol |
| Title: |
CD11c regulates late-stage T cell development in the thymus. |
| Volume: |
13 |
|
| Pages: |
1040818 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jawhara S |
| Year: |
2012 |
| Journal: |
J Immunol |
| Title: |
Integrin αXβ₂ is a leukocyte receptor for Candida albicans and is essential for protection against fungal infections. |
| Volume: |
189 |
| Issue: |
5 |
| Pages: |
2468-77 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hou L |
| Year: |
2024 |
| Journal: |
Front Immunol |
| Title: |
Integrin CD11c regulates B cell homeostasis. |
| Volume: |
15 |
|
| Pages: |
1359608 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu H |
| Year: |
2010 |
| Journal: |
Arterioscler Thromb Vasc Biol |
| Title: |
CD11c expression in adipose tissue and blood and its role in diet-induced obesity. |
| Volume: |
30 |
| Issue: |
2 |
| Pages: |
186-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Smith KA |
| Year: |
2012 |
| Journal: |
Infect Immun |
| Title: |
Type 2 innate immunity in helminth infection is induced redundantly and acts autonomously following CD11c(+) cell depletion. |
| Volume: |
80 |
| Issue: |
10 |
| Pages: |
3481-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Camper L |
| Year: |
2001 |
| Journal: |
Cell Tissue Res |
| Title: |
Distribution of the collagen-binding integrin alpha10beta1 during mouse development. |
| Volume: |
306 |
| Issue: |
1 |
| Pages: |
107-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huleatt JW |
| Year: |
1995 |
| Journal: |
J Immunol |
| Title: |
Antigen-driven induction of CD11c on intestinal intraepithelial lymphocytes and CD8+ T cells in vivo. |
| Volume: |
154 |
| Issue: |
11 |
| Pages: |
5684-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shelley CS |
| Year: |
2002 |
| Journal: |
J Immunol |
| Title: |
During differentiation of the monocytic cell line U937, Pur alpha mediates induction of the CD11c beta 2 integrin gene promoter. |
| Volume: |
168 |
| Issue: |
8 |
| Pages: |
3887-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kirby AC |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
Alveolar macrophages transport pathogens to lung draining lymph nodes. |
| Volume: |
183 |
| Issue: |
3 |
| Pages: |
1983-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sen D |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Selective and site-specific mobilization of dermal dendritic cells and Langerhans cells by Th1- and Th2-polarizing adjuvants. |
| Volume: |
107 |
| Issue: |
18 |
| Pages: |
8334-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
White AL |
| Year: |
2010 |
| Journal: |
Immunology |
| Title: |
Ligation of CD11c during vaccination promotes germinal centre induction and robust humoral responses without adjuvant. |
| Volume: |
131 |
| Issue: |
1 |
| Pages: |
141-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qualai J |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential. |
| Volume: |
11 |
| Issue: |
4 |
| Pages: |
e0154253 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sandor AM |
| Year: |
2019 |
| Journal: |
Front Immunol |
| Title: |
CD11c+ Cells Are Gatekeepers for Lymphocyte Trafficking to Infiltrated Islets During Type 1 Diabetes. |
| Volume: |
10 |
|
| Pages: |
99 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5637842 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2015-06-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610521 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:5637967 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
6 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6314783 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-06-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876724 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:6314789 |
| Age: |
embryonic day 16.0 |
|
| Note: |
Expression is in dendritic cells. |
| Specimen Label: |
E16 spleen |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6314783 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-06-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876727 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:6314789 |
| Age: |
postnatal day 2 |
|
| Note: |
Expression is in dendritic cells. |
| Specimen Label: |
Day 2 spleen |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6314783 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-06-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876728 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6314789 |
| Age: |
postnatal week 2 |
|
| Note: |
Expression is in dendritic cells. |
| Specimen Label: |
2 week spleen |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6314783 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-06-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876728 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6314789 |
| Age: |
postnatal week 6 |
|
| Note: |
Expression is in dendritic cells. |
| Specimen Label: |
6 week spleen |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7294406 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-06-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876728 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:7294415 |
| Age: |
postnatal adult |
| Image: |
5C CD11c |
| Note: |
Expression co-localized with Rtn1a in a minute population of cells. |
| Specimen Label: |
5C CD11c |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5637945 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1786821 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:5638113 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Expressed in the endothelial cells of the AV canal cushion. |
| Specimen Label: |
3F |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5637945 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268819 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:5638113 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
3E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5637945 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268821 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:5638113 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Slightly less expression. |
| Specimen Label: |
3F |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5796517 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-10-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1925228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5804010 |
| Age: |
postnatal |
|
|
| Specimen Label: |
6A control |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6314783 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-06-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3552327 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:6314789 |
| Age: |
postnatal day 2 |
|
| Note: |
Expression is in dendritic cells. |
| Specimen Label: |
Day 2 LN |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6314783 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-06-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3552328 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6314789 |
| Age: |
postnatal week 2 |
|
| Note: |
Expression is in dendritic cells. |
| Specimen Label: |
2 week LN |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6314783 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-06-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3552328 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6314789 |
| Age: |
postnatal week 6 |
|
| Note: |
Expression is in dendritic cells. |
| Specimen Label: |
6 week LN |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7294406 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-06-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3552328 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:7294415 |
| Age: |
postnatal adult |
| Image: |
4C CD11c |
| Note: |
Expression co-localized with Rtn1a in majority of cells. |
| Specimen Label: |
4C CD11c |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3710154 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-24 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752322 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:3710167 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression was mainly restricted to the subcapsular cortex of the thymus. |
| Specimen Label: |
2 E14.5 WT |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3710154 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-24 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752322 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:3710167 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression pattern in the mutant was less organized than the wild type. |
| Specimen Label: |
2 E14.5 PU.1-/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3710154 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-24 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752322 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:3710167 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
4 E14.5 WT |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3710154 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-24 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752322 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:3710167 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression level in the mutant was less than 10% of wild type. |
| Specimen Label: |
4 E14.5 PU.1-/- |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5637945 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268619 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:5638113 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Expressed in the endothelial cells of the AV canal cushion. |
| Specimen Label: |
3E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5796517 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-10-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3283428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5804010 |
| Age: |
postnatal |
|
|
| Specimen Label: |
6B SI control |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3710154 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-24 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876824 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:3710167 |
| Age: |
embryonic day 16.5 |
|
| Note: |
Expression was mainly restricted to the subcapsular cortex of the thymus. |
| Specimen Label: |
2 E16.5 WT |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3710154 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-24 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876824 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:3710167 |
| Age: |
embryonic day 16.5 |
|
| Note: |
Expression levels were near wild type. Expression pattern in the mutant was less organized than the wild type. |
| Specimen Label: |
2 E16.5 PU.1-/- |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3710154 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-24 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876824 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:3710167 |
| Age: |
embryonic day 16.5 |
|
|
| Specimen Label: |
4 E16.5 WT |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3710154 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2007-05-24 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876824 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:3710167 |
| Age: |
embryonic day 16.5 |
|
| Note: |
Expression level in the mutant was approximately 70% of wild type. |
| Specimen Label: |
4 E16.5 PU.1-/- |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5637945 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5638113 |
| Age: |
postnatal month 1 |
|
|
| Specimen Label: |
not shown |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6314783 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-06-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876824 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:6314789 |
| Age: |
embryonic day 16.0 |
|
| Note: |
Expression is in dendritic cells. |
| Specimen Label: |
E16 thymus |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6314783 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-06-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876827 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:6314789 |
| Age: |
postnatal day 2 |
|
| Note: |
Expression is in dendritic cells. |
| Specimen Label: |
Day 2 thymus |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6314783 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-06-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876828 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6314789 |
| Age: |
postnatal week 2 |
|
| Note: |
Expression is in dendritic cells. |
| Specimen Label: |
2 week thymus |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6314783 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-06-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876828 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6314789 |
| Age: |
postnatal week 6 |
|
| Note: |
Expression is in dendritic cells. |
| Specimen Label: |
6 week thymus |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7294406 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-06-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876828 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:7294415 |
| Age: |
postnatal adult |
| Image: |
3C CD11c |
| Note: |
Expression co-localized with Rtn1a in majority of cells. |
| Specimen Label: |
3C CD11c |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5637945 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3643819 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:5638113 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Expressed in the mesenchymal cells inside the cardiac jelly. |
| Specimen Label: |
3E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5637945 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-03 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3643821 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:5638113 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Expressed in the mesenchymal cells inside the cardiac jelly. |
| Specimen Label: |
3F |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6314783 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-06-25 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876524 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:6314789 |
| Age: |
embryonic day 16.0 |
|
| Note: |
Expression is in dendritic cells in the lymph node. |
| Specimen Label: |
E16 LN |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang X |
| Year: |
2000 |
| Journal: |
GenBank Submission |
| Title: |
Mus musculus leukocyte adhesion glycoprotein p150,95 alpha integrin subunit mRNA, complete cds |
|
|
| Pages: |
AF211864 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bates JT |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
Direct stimulation of tlr5+/+ CD11c+ cells is necessary for the adjuvant activity of flagellin. |
| Volume: |
182 |
| Issue: |
12 |
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7539-47 |
|
•
•
•
•
•
|
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| First Author: |
Huang QQ |
| Year: |
2015 |
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Nat Commun |
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CD11c-mediated deletion of Flip promotes autoreactivity and inflammatory arthritis. |
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|
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7086 |
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•
•
•
•
•
|
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Teichmann LL |
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2015 |
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Immunity |
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Local triggering of the ICOS coreceptor by CD11c(+) myeloid cells drives organ inflammation in lupus. |
| Volume: |
42 |
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3 |
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552-65 |
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| First Author: |
Wlodarczyk A |
| Year: |
2017 |
| Journal: |
EMBO J |
| Title: |
A novel microglial subset plays a key role in myelinogenesis in developing brain. |
| Volume: |
36 |
| Issue: |
22 |
| Pages: |
3292-3308 |
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| First Author: |
Kamphuis W |
| Year: |
2016 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Transcriptional profiling of CD11c-positive microglia accumulating around amyloid plaques in a mouse model for Alzheimer's disease. |
| Volume: |
1862 |
| Issue: |
10 |
| Pages: |
1847-60 |
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| First Author: |
Mencarelli A |
| Year: |
2018 |
| Journal: |
Nat Commun |
| Title: |
Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis. |
| Volume: |
9 |
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1 |
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1102 |
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| First Author: |
Mott KR |
| Year: |
2008 |
| Journal: |
J Virol |
| Title: |
Lymphoid-related CD11c+ CD8alpha+ dendritic cells are involved in enhancing herpes simplex virus type 1 latency. |
| Volume: |
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| Issue: |
20 |
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9870-9 |
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Khare A |
| Year: |
2013 |
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J Immunol |
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Cutting edge: inhaled antigen upregulates retinaldehyde dehydrogenase in lung CD103+ but not plasmacytoid dendritic cells to induce Foxp3 de novo in CD4+ T cells and promote airway tolerance. |
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25-9 |
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Alnaeeli M |
| Year: |
2006 |
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J Immunol |
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Immune interactions with CD4+ T cells promote the development of functional osteoclasts from murine CD11c+ dendritic cells. |
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| Year: |
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Parasite Immunol |
| Title: |
Deletion of the complement phagocytic receptors CR3 and CR4 does not alter susceptibility to experimental cerebral malaria. |
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| Year: |
2010 |
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J Immunol |
| Title: |
CD11c+ dendritic cells and B cells contribute to the tumoricidal activity of anti-DR5 antibody therapy in established tumors. |
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| Year: |
2005 |
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Cell Immunol |
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4-1BB costimulation enhances HSV-1-specific CD8+ T cell responses by the induction of CD11c+CD8+ T cells. |
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A novel association between resident tissue macrophages and nerves in the peripheral stroma of the murine cornea. |
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2021 |
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CD11c participates in triggering acute graft-versus-host disease during bone marrow transplantation. |
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| Year: |
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