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Search results 1 to 100 out of 101 for Kif22

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Hits by Strain

Type Details Score
Gene
3835 | KIF22
Type: gene
Organism: human
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Gene
394855 | kif22
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR026986 | KIF22
Type: Family
Description: Kinesin-like protein KIF22 (also known as kinesin-like DNA-binding protein, Kid) is a chromokinesin that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis [, , ]. KIF22 is associated with chromosome arms and plays an important part in producing the polar ejection forces that move chromosome arms toward the spindle equator at metaphase during mitosis []. Its destruction is needed for anaphase chromosome movement []. Depletion of KIF22 caused abnormal chromosome arm orientation, delayed chromosome congression, and sensitised cells to nocodazole []. Defects in KIF22 are the cause of spondyloepimetaphyseal dysplasia with joint laxity, type 2 (SEMDJL2), a bone disease characterised by short stature, distinctive midface retrusion, progressive knee malalignment, generalised ligamentous laxity, and mild spinal deformity [, ].
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Gene
293502 | Kif22
Type: gene
Organism: rat
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Gene
489938 | KIF22
Type: gene
Organism: dog, domestic
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Gene
454026 | KIF22
Type: gene
Organism: chimpanzee
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Gene
506294 | KIF22
Type: gene
Organism: cattle
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Gene
561788 | kif22
Type: gene
Organism: zebrafish
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Gene
706401 | KIF22
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:109233 | Kif22
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:7570102
Assay Type: RNA in situ
Annotation Date: 2024-01-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7570119
Age: embryonic day 14.5
Image: S4a Kif22
Note: Expression in cortical plate and ventricular zone of cortex.
Specimen Label: S4a Kif22
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7570102
Assay Type: RNA in situ
Annotation Date: 2024-01-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7570119
Age: embryonic day 14.5
Image: S4a Kif22
Note: Expression in cortical plate and ventricular zone of cortex.
Specimen Label: S4a Kif22
Detected: true
Specimen Num: 1
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Publication
22152677 | -
First Author: Min BJ
Year: 2011
Journal: Am J Hum Genet
Title: Whole-exome sequencing identifies mutations of KIF22 in spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type.
Volume: 89
Issue: 6
Pages: 760-6
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Publication
22152678 | -
First Author: Boyden ED
Year: 2011
Journal: Am J Hum Genet
Title: Recurrent dominant mutations affecting two adjacent residues in the motor domain of the monomeric kinesin KIF22 result in skeletal dysplasia and joint laxity.
Volume: 89
Issue: 6
Pages: 767-72
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Protein
A0A0U1RPH8
Organism: Mus musculus/domesticus
Length: 161  
Fragment?: true
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Protein
Q3V300
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
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Publication
22945934 | -
First Author: Wandke C
Year: 2012
Journal: J Cell Biol
Title: Human chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosis.
Volume: 198
Issue: 5
Pages: 847-63
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Publication
10966104 | -
First Author: Funabiki H
Year: 2000
Journal: Cell
Title: The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement.
Volume: 102
Issue: 4
Pages: 411-24
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Publication
10966105 | -
First Author: Antonio C
Year: 2000
Journal: Cell
Title: Xkid, a chromokinesin required for chromosome alignment on the metaphase plate.
Volume: 102
Issue: 4
Pages: 425-35
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Publication
12360284 | -
First Author: Perez LH
Year: 2002
Journal: Nat Cell Biol
Title: Xkid chromokinesin is required for the meiosis I to meiosis II transition in Xenopus laevis oocytes.
Volume: 4
Issue: 10
Pages: 737-42
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Publication
38989461 | J:351469
First Author: Kawaue H
Year: 2024
Journal: iScience
Title: KIF22 regulates mitosis and proliferation of chondrocyte cells.
Volume: 27
Issue: 7
Pages: 110151
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Publication
9339368 | J:43498
First Author: Yang Z
Year: 1997
Journal: Genomics
Title: Identification, partial characterization, and genetic mapping of kinesin-like protein genes in mouse.
Volume: 45
Issue: 1
Pages: 123-31
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Protein Coding Gene
MGP_CAROLIEiJ_G0030484 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033018 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033001 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032933 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033006 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032716 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_109233 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033512 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032045 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032689 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032841 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032794 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032935 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032826 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033531 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031752 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032157 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013694 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031598 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
18329364 | J:145315
First Author: Ohsugi M
Year: 2008
Journal: Cell
Title: Kid-mediated chromosome compaction ensures proper nuclear envelope formation.
Volume: 132
Issue: 5
Pages: 771-82
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Publication
12692123 | J:84108
First Author: Shiroguchi K
Year: 2003
Journal: J Biol Chem
Title: The second microtubule-binding site of monomeric kid enhances the microtubule affinity.
Volume: 278
Issue: 25
Pages: 22460-5
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Publication
27550518 | J:246572
First Author: Soeda S
Year: 2016
Journal: J Cell Sci
Title: The microtubule-binding and coiled-coil domains of Kid are required to turn off the polar ejection force at anaphase.
Volume: 129
Issue: 19
Pages: 3609-3619
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GXD Expression
GXD Expression
Probe: MGI:3070145
Assay Type: RNA in situ
Annotation Date: 2005-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Pattern: Not Specified
Stage: TS05
Assay Id: MGI:3607279
Age: embryonic day 3.5
Image: blastocyst
Note: When a less concentrated dilution of probe is used, no expression is seen.
Specimen Label: blastocyst
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1028290
Assay Type: RNA in situ
Annotation Date: 2023-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7525218
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1028290
Assay Type: RNA in situ
Annotation Date: 2023-09-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7525218
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7569343
Assay Type: Immunohistochemistry
Annotation Date: 2024-01-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7570108
Age: embryonic day 13.5
Image: S4b WT
Specimen Label: S4b WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7569343
Assay Type: Immunohistochemistry
Annotation Date: 2024-01-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7570108
Age: embryonic day 13.5
Image: S4b HeCo
Note: Authors report altered expression in ventricular zone.
Specimen Label: S4b HeCo
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3070145
Assay Type: RNA in situ
Annotation Date: 2005-12-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160465
Stage: TS05
Assay Id: MGI:3607279
Age: embryonic day 3.5
Image: blastocyst
Note: Expression levels are lower in the trophectoderm than in the inner cell mass.
Specimen Label: blastocyst
Detected: false
Specimen Num: 1
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Publication
11884614 | J:75489
First Author: Dickins RA
Year: 2002
Journal: Mol Cell Biol
Title: The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice.
Volume: 22
Issue: 7
Pages: 2294-303
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Publication
10349636 | J:80645
 
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
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Publication
29229923 | J:317479
First Author: Bizzotto S
Year: 2017
Journal: Sci Rep
Title: Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex.
Volume: 7
Issue: 1
Pages: 17308
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Publication
32492419 | J:306456
First Author: Farini D
Year: 2020
Journal: Cell Rep
Title: A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.
Volume: 31
Issue: 9
Pages: 107703
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Publication
38196272 | J:347631
First Author: Li C
Year: 2024
Journal: Adv Sci (Weinh)
Title: Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes.
Volume: 11
Issue: 11
Pages: e2305992
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Publication
16325481 | J:102143
First Author: Yoshikawa T
Year: 2006
Journal: Gene Expr Patterns
Title: High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.
Volume: 6
Issue: 2
Pages: 213-24
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: Kinesin-like protein KIF22
Type: chain
End: 660
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Protein
A0A0U1RNY7
Organism: Mus musculus/domesticus
Length: 151  
Fragment?: true
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DO Term
DOID:0112199 | spondyloepimetaphyseal dysplasia with joint laxity type 2
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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