| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
LEM domain-containing protein 2 (LEMD2 or LEM2) is an inner nuclear membrane protein associated with A-type lamins that is involved in nuclear structure organization [, ]. It also plays a role in embryonic development and in the regulation of several signaling pathways [].LEM2 contains an N-terminal LEM domain, two putative transmembrane domains and a MAN1-Src1p C-terminal (MSC) domain, but lacks the Man1-specific C-terminal RNA recognition motif (RRM) []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tapia O |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
Nuclear envelope protein Lem2 is required for mouse development and regulates MAP and AKT kinases. |
| Volume: |
10 |
| Issue: |
3 |
| Pages: |
e0116196 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brachner A |
| Year: |
2005 |
| Journal: |
J Cell Sci |
| Title: |
LEM2 is a novel MAN1-related inner nuclear membrane protein associated with A-type lamins. |
| Volume: |
118 |
| Issue: |
Pt 24 |
| Pages: |
5797-810 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen R |
| Year: |
2023 |
| Journal: |
Circ Res |
| Title: |
Mechanistic Insights of the LEMD2 p.L13R Mutation and Its Role in Cardiomyopathy. |
| Volume: |
132 |
| Issue: |
2 |
| Pages: |
e43-e58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Caravia XM |
| Year: |
2022 |
| Journal: |
J Clin Invest |
| Title: |
Loss of function of the nuclear envelope protein LEMD2 causes DNA damage-dependent cardiomyopathy. |
| Volume: |
132 |
| Issue: |
22 |
|
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
511
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
125
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ulbert S |
| Year: |
2006 |
| Journal: |
FEBS Lett |
| Title: |
The inner nuclear membrane protein Lem2 is critical for normal nuclear envelope morphology. |
| Volume: |
580 |
| Issue: |
27 |
| Pages: |
6435-41 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2677398 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-01-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610517 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5705854 |
| Age: |
embryonic day 10.5 |
| Image: |
6C Heart Lemd2 +/+ |
|
| Specimen Label: |
6C Heart Lemd2 +/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2677398 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-01-29 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610517 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5705854 |
| Age: |
embryonic day 10.5 |
| Image: |
6C Heart Lemd2 Gt/Gt |
| Note: |
Increased levels of expression compared with wild type embryos. |
| Specimen Label: |
6C Heart Lemd2 Gt/Gt |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2677398 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-02-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610517 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5706766 |
| Age: |
embryonic day 10.5 |
| Image: |
6C Heart Lemd2 +/+ |
|
| Specimen Label: |
6C Heart Lemd2 +/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2677398 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-02-02 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610517 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5706766 |
| Age: |
embryonic day 10.5 |
| Image: |
6C Heart Lemd2 Gt/Gt |
| Note: |
Increased levels of expression compared with wild type embryos. |
| Specimen Label: |
6C Heart Lemd2 Gt/Gt |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2677398 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-01-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3116917 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5705854 |
| Age: |
embryonic day 10.5 |
| Image: |
6C Somites Lemd2 +/+ |
|
| Specimen Label: |
6C Somites Lemd2 +/+ |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2677398 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-01-29 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3116917 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5705854 |
| Age: |
embryonic day 10.5 |
| Image: |
6C Somites Lemd2 Gt/Gt |
| Note: |
Increased levels of expression compared with wild type embryos. |
| Specimen Label: |
6C Somites Lemd2 Gt/Gt |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2677398 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-02-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3116917 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5706766 |
| Age: |
embryonic day 10.5 |
| Image: |
6C Somites Lemd2 +/+ |
|
| Specimen Label: |
6C Somites Lemd2 +/+ |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2677398 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-02-02 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3116917 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5706766 |
| Age: |
embryonic day 10.5 |
| Image: |
6C Somites Lemd2 Gt/Gt |
| Note: |
Increased levels of expression compared with wild type embryos. |
| Specimen Label: |
6C Somites Lemd2 Gt/Gt |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705824 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2016-01-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603921 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:5705851 |
| Age: |
embryonic day 13.5 |
| Image: |
1 |
|
| Specimen Label: |
+/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705824 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2016-01-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603921 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:5705851 |
| Age: |
embryonic day 13.5 |
| Image: |
1 |
|
| Specimen Label: |
+/Gt |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706593 |
| Age: |
embryonic day 10.5 |
| Image: |
1 |
|
| Specimen Label: |
+/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706593 |
| Age: |
embryonic day 10.5 |
| Image: |
1 |
|
| Specimen Label: |
+/Gt |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706593 |
| Age: |
embryonic day 10.5 |
| Image: |
1 |
|
| Specimen Label: |
Gt/Gt |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706594 |
| Age: |
embryonic day 10.5 |
| Image: |
S1 |
|
| Specimen Label: |
E10.5 +/+ |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706594 |
| Age: |
embryonic day 10.5 |
| Image: |
S1 |
|
| Specimen Label: |
E10.5 +/Gt |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706594 |
| Age: |
embryonic day 10.5 |
| Image: |
S1 |
|
| Specimen Label: |
E10.5 Gt/Gt |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603913 |
|
| Stage: |
TS13 |
| Assay Id: |
MGI:5706594 |
| Age: |
embryonic day 8.5 |
| Image: |
S1 |
|
| Specimen Label: |
E8.5 +/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603913 |
|
| Stage: |
TS13 |
| Assay Id: |
MGI:5706594 |
| Age: |
embryonic day 8.5 |
| Image: |
S1 |
|
| Specimen Label: |
E8.5 +/Gt |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603913 |
|
| Stage: |
TS13 |
| Assay Id: |
MGI:5706594 |
| Age: |
embryonic day 8.5 |
| Image: |
S1 |
|
| Specimen Label: |
E8.5 Gt/Gt |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603921 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:5706594 |
| Age: |
embryonic day 13.5 |
| Image: |
S1 |
|
| Specimen Label: |
E13.5 +/+ |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603921 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:5706594 |
| Age: |
embryonic day 13.5 |
| Image: |
S1 |
|
| Specimen Label: |
E13.5 +/Gt |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603921 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:5706594 |
| Age: |
embryonic day 13.5 |
| Image: |
S1 |
|
| Specimen Label: |
E13.5 Gt/Gt |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3586628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5706596 |
| Age: |
postnatal adult |
| Image: |
S1 |
|
| Specimen Label: |
+/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3586628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5706596 |
| Age: |
postnatal adult |
| Image: |
S1 |
|
| Specimen Label: |
+/+ |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3586628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5706596 |
| Age: |
postnatal adult |
| Image: |
S1 |
|
| Specimen Label: |
+/+ |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3586628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5706596 |
| Age: |
postnatal adult |
| Image: |
S1 |
|
| Specimen Label: |
+/Gt |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3586628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5706596 |
| Age: |
postnatal adult |
| Image: |
S1 |
|
| Specimen Label: |
+/Gt |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3586628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5706596 |
| Age: |
postnatal adult |
| Image: |
S1 |
|
| Specimen Label: |
+/Gt |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706597 |
| Age: |
embryonic day 10.5 |
| Image: |
6 |
|
| Specimen Label: |
+/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706597 |
| Age: |
embryonic day 10.5 |
| Image: |
6 |
|
| Specimen Label: |
+/+ |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706597 |
| Age: |
embryonic day 10.5 |
| Image: |
6 |
|
| Specimen Label: |
+/+ |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706597 |
| Age: |
embryonic day 10.5 |
| Image: |
6 |
|
| Specimen Label: |
+/+ |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706597 |
| Age: |
embryonic day 10.5 |
| Image: |
6 |
|
| Specimen Label: |
Gt/Gt |
| Detected: |
false |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706597 |
| Age: |
embryonic day 10.5 |
| Image: |
6 |
|
| Specimen Label: |
Gt/Gt |
| Detected: |
false |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706597 |
| Age: |
embryonic day 10.5 |
| Image: |
6 |
|
| Specimen Label: |
Gt/Gt |
| Detected: |
false |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5705833 |
| Assay Type: |
Western blot |
| Annotation Date: |
2016-02-01 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:5706597 |
| Age: |
embryonic day 10.5 |
| Image: |
6 |
|
| Specimen Label: |
Gt/Gt |
| Detected: |
false |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7331388 |
| Assay Type: |
Western blot |
| Annotation Date: |
2022-08-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7331408 |
| Age: |
postnatal day 17 |
| Image: |
2 |
|
| Specimen Label: |
WT |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7331388 |
| Assay Type: |
Western blot |
| Annotation Date: |
2022-08-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7331408 |
| Age: |
postnatal day 17 |
| Image: |
2 |
|
| Specimen Label: |
WT |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7331388 |
| Assay Type: |
Western blot |
| Annotation Date: |
2022-08-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7331408 |
| Age: |
postnatal day 17 |
| Image: |
2 |
|
| Specimen Label: |
KO |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7331388 |
| Assay Type: |
Western blot |
| Annotation Date: |
2022-08-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7331408 |
| Age: |
postnatal day 17 |
| Image: |
2 |
|
| Specimen Label: |
KO |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2016-01-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610517 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5705852 |
| Age: |
embryonic day 10.5 |
| Image: |
2C Mesoderm |
|
| Specimen Label: |
2C Mesoderm |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2016-01-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
| Pattern: |
Widespread |
| Stage: |
TS17 |
| Assay Id: |
MGI:5705852 |
| Age: |
embryonic day 10.5 |
| Image: |
2A (left) |
| Note: |
Authors report variable levels of expression throughout the embryo. |
| Specimen Label: |
2A (left) |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2016-01-29 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:5705852 |
| Age: |
embryonic day 10.5 |
| Image: |
2A (right) |
| Note: |
Slightly higher expression sometimes seen in developing liver, Wolffian duct and certain areas of neurectoderm. |
| Specimen Label: |
2A (right) |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2016-01-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603921 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:5705852 |
| Age: |
embryonic day 13.5 |
| Image: |
2B (left) |
|
| Specimen Label: |
2B (left) |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2016-01-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603921 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:5705852 |
| Age: |
embryonic day 13.5 |
| Image: |
2B (right) |
|
| Specimen Label: |
2B (right) |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2016-01-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684617 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5705852 |
| Age: |
embryonic day 10.5 |
| Image: |
2A (right) |
|
| Specimen Label: |
2A (right) |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2016-01-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684617 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5705852 |
| Age: |
embryonic day 10.5 |
| Image: |
2C Endoderm |
|
| Specimen Label: |
2C Endoderm |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2016-01-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1616417 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5705852 |
| Age: |
embryonic day 10.5 |
| Image: |
2A (right) |
|
| Specimen Label: |
2A (right) |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2016-01-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1616417 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5705852 |
| Age: |
embryonic day 10.5 |
| Image: |
2C Ectoderm |
|
| Specimen Label: |
2C Ectoderm |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2016-01-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1657717 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5705852 |
| Age: |
embryonic day 10.5 |
| Image: |
2A (right) |
|
| Specimen Label: |
2A (right) |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huber MD |
| Year: |
2009 |
| Journal: |
Mol Cell Biol |
| Title: |
Overlapping functions of nuclear envelope proteins NET25 (Lem2) and emerin in regulation of extracellular signal-regulated kinase signaling in myoblast differentiation. |
| Volume: |
29 |
| Issue: |
21 |
| Pages: |
5718-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ramirez-Martinez A |
| Year: |
2021 |
| Journal: |
Nat Commun |
| Title: |
The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
690 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ross JA |
| Year: |
2023 |
| Journal: |
Cardiovasc Res |
| Title: |
Lem2 is essential for cardiac development by maintaining nuclear integrity. |
| Volume: |
119 |
| Issue: |
11 |
| Pages: |
2074-2088 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Mammalian Genetics Unit at Harwell |
| Year: |
2004 |
| Journal: |
Unpublished |
| Title: |
Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Strausberg RL |
| Year: |
2002 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
| Volume: |
99 |
| Issue: |
26 |
| Pages: |
16899-903 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
NIH Mouse Knockout Inventory |
| Year: |
2004 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the NIH Mouse Knockout Inventory |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI and IMPC |
| Year: |
2018 |
| Journal: |
Database Release |
| Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wellcome Trust Sanger Institute |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Magdaleno S |
| Year: |
2006 |
| Journal: |
PLoS Biol |
| Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
| Volume: |
4 |
| Issue: |
4 |
| Pages: |
e86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|