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Search results 1 to 100 out of 2308 for Lep

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0.011s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: horse
Gene
Type: gene
Organism: pig, domestic
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication  
First Author: Roh YJ
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: Dipterocarpus tuberculatus as a promising anti-obesity treatment in Lep knockout mice.
Volume: 14
Pages: 1167285
Publication
First Author: Sekiya M
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep ob/ob mice.
Volume: 387
Issue: 3
Pages: 511-5
Publication
First Author: Sekiya M
Year: 2004
Journal: J Biol Chem
Title: Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice.
Volume: 279
Issue: 15
Pages: 15084-90
Publication
First Author: Chua S Jr
Year: 2002
Journal: Diabetologia
Title: Differential beta cell responses to hyperglycaemia and insulin resistance in two novel congenic strains of diabetes (FVB- Lepr (db)) and obese (DBA- Lep (ob)) mice.
Volume: 45
Issue: 7
Pages: 976-90
Publication
First Author: King AM
Year: 2013
Journal: Infect Immun
Title: Leptospiral outer membrane protein LipL41 is not essential for acute leptospirosis but requires a small chaperone protein, lep, for stable expression.
Volume: 81
Issue: 8
Pages: 2768-76
Protein Domain
Type: Family
Description: Members of this protein family are Lep, an outer membrane lipoprotein LipL41-binding protein that appears to function as a chaperone important to its expression. LipL41 is the third most abundant lipoprotein in the pathogen Leptospira interrogans, but is found in saprophytic Leptospira species as well and is not essential for virulence [].
Publication
First Author: Ogawa Y
Year: 1999
Journal: Diabetes
Title: Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin.
Volume: 48
Issue: 9
Pages: 1822-9
Publication
First Author: Matsuoka N
Year: 2001
Journal: Am J Physiol Endocrinol Metab
Title: Decreased triglyceride-rich lipoproteins in transgenic skinny mice overexpressing leptin.
Volume: 280
Issue: 2
Pages: E334-9
Publication
First Author: Chung WK
Year: 1997
Journal: Obes Res
Title: Polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLP) and electrophoretic assays for the mouse obese (Lepob) mutation.
Volume: 5
Issue: 3
Pages: 183-5
Publication
First Author: Suganami E
Year: 2004
Journal: Diabetes
Title: Leptin stimulates ischemia-induced retinal neovascularization: possible role of vascular endothelial growth factor expressed in retinal endothelial cells.
Volume: 53
Issue: 9
Pages: 2443-8
Publication
First Author: Yamada N
Year: 2011
Journal: Endocrinology
Title: Impaired CNS leptin action is implicated in depression associated with obesity.
Volume: 152
Issue: 7
Pages: 2634-43
Publication
First Author: Elefteriou F
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Serum leptin level is a regulator of bone mass.
Volume: 101
Issue: 9
Pages: 3258-63
Publication
First Author: Ebihara K
Year: 2001
Journal: Diabetes
Title: Transgenic overexpression of leptin rescues insulin resistance and diabetes in a mouse model of lipoatrophic diabetes.
Volume: 50
Issue: 6
Pages: 1440-8
Publication
First Author: Aizawa-Abe M
Year: 2000
Journal: J Clin Invest
Title: Pathophysiological role of leptin in obesity-related hypertension.
Volume: 105
Issue: 9
Pages: 1243-52
Publication
First Author: Masuzaki H
Year: 1999
Journal: Diabetes
Title: Glucose metabolism and insulin sensitivity in transgenic mice overexpressing leptin with lethal yellow agouti mutation: usefulness of leptin for the treatment of obesity-associated diabetes.
Volume: 48
Issue: 8
Pages: 1615-22
Publication
First Author: Roh JI
Year: 2018
Journal: Exp Anim
Title: CRISPR-Cas9-mediated generation of obese and diabetic mouse models.
Volume: 67
Issue: 2
Pages: 229-237
Publication
First Author: Okamoto K
Year: 2006
Journal: Brain Res
Title: Sterol regulatory element binding protein (SREBP)-1 expression in brain is affected by age but not by hormones or metabolic changes.
Volume: 1081
Issue: 1
Pages: 19-27
Publication
First Author: Wrann CD
Year: 2012
Journal: J Clin Invest
Title: FOSL2 promotes leptin gene expression in human and mouse adipocytes.
Volume: 122
Issue: 3
Pages: 1010-21
Publication
First Author: Yook JS
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Leptin in hippocampus mediates benefits of mild exercise by an antioxidant on neurogenesis and memory.
Volume: 116
Issue: 22
Pages: 10988-10993
Publication
First Author: Cleary MP
Year: 2003
Journal: Breast Cancer Res Treat
Title: Genetically obese MMTV-TGF-alpha/Lep(ob)Lep(ob) female mice do not develop mammary tumors.
Volume: 77
Issue: 3
Pages: 205-15
Publication
First Author: Trevaskis JL
Year: 2008
Journal: Endocrinology
Title: Counterintuitive effects of double-heterozygous null melanocortin-4 receptor and leptin genes on diet-induced obesity and insulin resistance in C57BL/6J mice.
Volume: 149
Issue: 1
Pages: 174-84
Publication
First Author: Trevaskis JL
Year: 2005
Journal: Endocrinology
Title: Double leptin and melanocortin-4 receptor gene mutations have an additive effect on fat mass and are associated with reduced effects of leptin on weight loss and food intake.
Volume: 146
Issue: 10
Pages: 4257-65
Publication
First Author: Chung WK
Year: 1998
Journal: Am J Physiol
Title: Heterozygosity for Lep(ob) or Lep(rdb) affects body composition and leptin homeostasis in adult mice.
Volume: 274
Issue: 4 Pt 2
Pages: R985-90
Publication
First Author: Joost HG
Year: 2014
Journal: Mamm Genome
Title: The genetic basis of obesity-associated type 2 diabetes (diabesity) in polygenic mouse models.
Volume: 25
Issue: 9-10
Pages: 401-12
Publication  
First Author: Roh Y
Year: 2024
Journal: Int J Mol Sci
Title: Impact of the Oral Administration of Polystyrene Microplastics on Hepatic Lipid, Glucose, and Amino Acid Metabolism in C57BL/6Korl and C57BL/6-Lep(em1hwl)/Korl Mice.
Volume: 25
Issue: 9
Publication
First Author: Pfuhlmann K
Year: 2018
Journal: Diabetes
Title: Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1.
Volume: 67
Issue: 11
Pages: 2456-2465
Publication
First Author: Lo KA
Year: 2018
Journal: Diabetes
Title: Adipocyte Long-Noncoding RNA Transcriptome Analysis of Obese Mice Identified Lnc-Leptin, Which Regulates Leptin.
Volume: 67
Issue: 6
Pages: 1045-1056
Publication
First Author: Pathak RR
Year: 2013
Journal: J Biol Chem
Title: Loss of phosphatase and tensin homolog (PTEN) induces leptin-mediated leptin gene expression: feed-forward loop operating in the lung.
Volume: 288
Issue: 41
Pages: 29821-35
Publication
First Author: Dallner OS
Year: 2019
Journal: Nat Med
Title: Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity.
Volume: 25
Issue: 3
Pages: 507-516
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Wei Z
Year: 2012
Journal: J Biol Chem
Title: C1q/TNF-related protein-12 (CTRP12), a novel adipokine that improves insulin sensitivity and glycemic control in mouse models of obesity and diabetes.
Volume: 287
Issue: 13
Pages: 10301-15
Publication
First Author: Kebede M
Year: 2008
Journal: Diabetes
Title: Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion: a new mechanism for fat-induced impairment of beta-cell function.
Volume: 57
Issue: 7
Pages: 1887-95
Publication
First Author: Cowherd RB
Year: 2010
Journal: Am J Pathol
Title: Adiponectin lowers glucose production by increasing SOGA.
Volume: 177
Issue: 4
Pages: 1936-45
Publication
First Author: Chehab FF
Year: 1996
Journal: Nat Genet
Title: Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin.
Volume: 12
Issue: 3
Pages: 318-20
Publication
First Author: Cassano S
Year: 2014
Journal: Metabolism
Title: Leptin modulates autophagy in human CD4+CD25- conventional T cells.
Volume: 63
Issue: 10
Pages: 1272-9
Publication
First Author: Hong CJ
Year: 2010
Journal: PLoS One
Title: ENU mutagenesis identifies mice with morbid obesity and severe hyperinsulinemia caused by a novel mutation in leptin.
Volume: 5
Issue: 12
Pages: e15333
Publication
First Author: Krautkramer KA
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line.
Volume: 305
Issue: 5
Pages: E600-10
Publication
First Author: INGALLS AM
Year: 1950
Journal: J Hered
Title: Obese, a new mutation in the house mouse.
Volume: 41
Issue: 12
Pages: 317-8
Publication
First Author: Everard A
Year: 2011
Journal: Diabetes
Title: Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice.
Volume: 60
Issue: 11
Pages: 2775-86
Publication
First Author: Elinav E
Year: 2006
Journal: J Pathol
Title: Adoptive transfer of regulatory NKT lymphocytes ameliorates non-alcoholic steatohepatitis and glucose intolerance in ob/ob mice and is associated with intrahepatic CD8 trapping.
Volume: 209
Issue: 1
Pages: 121-8
Publication
First Author: Lanner JT
Year: 2006
Journal: Diabetes
Title: The role of Ca2+ influx for insulin-mediated glucose uptake in skeletal muscle.
Volume: 55
Issue: 7
Pages: 2077-83
Publication
First Author: Macia L
Year: 2006
Journal: J Immunol
Title: Impairment of dendritic cell functionality and steady-state number in obese mice.
Volume: 177
Issue: 9
Pages: 5997-6006
Publication
First Author: Silvani A
Year: 2009
Journal: Hypertension
Title: Sleep modulates hypertension in leptin-deficient obese mice.
Volume: 53
Issue: 2
Pages: 251-5
Publication  
First Author: Dickie MM
Year: 1957
Journal: Mouse News Lett
Title: [Linkage of ob to L.G. XI]
Volume: 17
Pages: 52
Publication
First Author: Gao M
Year: 2019
Journal: Sci Rep
Title: Controlling Obesity and Metabolic Diseases by Hydrodynamic Delivery of a Fusion Gene of Exendin-4 and α1 Antitrypsin.
Volume: 9
Issue: 1
Pages: 13427
Publication
First Author: Jalabert A
Year: 2021
Journal: Sci Rep
Title: Profiling of ob/ob mice skeletal muscle exosome-like vesicles demonstrates combined action of miRNAs, proteins and lipids to modulate lipid homeostasis in recipient cells.
Volume: 11
Issue: 1
Pages: 21626
Publication
First Author: Lubitz I
Year: 2014
Journal: Neurobiol Aging
Title: Non-viability of crossing the Alzheimer mouse model Tg2576 with the type 2 diabetes mouse model ob/ob.
Volume: 35
Issue: 7
Pages: e19-20
Publication
First Author: Pajvani UB
Year: 2005
Journal: Nat Med
Title: Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy.
Volume: 11
Issue: 7
Pages: 797-803
Publication
First Author: Burak MF
Year: 2015
Journal: Sci Transl Med
Title: Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Volume: 7
Issue: 319
Pages: 319ra205
Publication
First Author: Askari B
Year: 2014
Journal: Lab Invest
Title: Effects of CP-900691, a novel peroxisome proliferator-activated receptor α, agonist on diabetic nephropathy in the BTBR ob/ob mouse.
Volume: 94
Issue: 8
Pages: 851-62
Publication
First Author: Hung YH
Year: 2019
Journal: Physiol Genomics
Title: Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice.
Volume: 51
Issue: 8
Pages: 379-389
Publication
First Author: Kim YD
Year: 2008
Journal: Diabetes
Title: Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP.
Volume: 57
Issue: 2
Pages: 306-14
Publication
First Author: Üner AG
Year: 2019
Journal: Sci Rep
Title: Role of POMC and AgRP neuronal activities on glycaemia in mice.
Volume: 9
Issue: 1
Pages: 13068
Publication
First Author: Ip CK
Year: 2021
Journal: STAR Protoc
Title: An optimized protocol for establishing a chronic stress model in mice.
Volume: 2
Issue: 2
Pages: 100448
Publication
First Author: Soukas A
Year: 2000
Journal: Genes Dev
Title: Leptin-specific patterns of gene expression in white adipose tissue.
Volume: 14
Issue: 8
Pages: 963-80
Publication
First Author: Vicent D
Year: 1998
Journal: Diabetes
Title: Alterations in skeletal muscle gene expression of ob/ob mice by mRNA differential display.
Volume: 47
Issue: 9
Pages: 1451-8
Publication
First Author: Tubbs E
Year: 2014
Journal: Diabetes
Title: Mitochondria-associated endoplasmic reticulum membrane (MAM) integrity is required for insulin signaling and is implicated in hepatic insulin resistance.
Volume: 63
Issue: 10
Pages: 3279-94
Publication
First Author: Chen H
Year: 2021
Journal: Cell Rep
Title: Dissecting mammalian spermatogenesis using spatial transcriptomics.
Volume: 37
Issue: 5
Pages: 109915
Publication
First Author: MacDonald S
Year: 1998
Journal: Neurosci Lett
Title: Expression of beta-endorphin and its receptors in the spinal cord of obese-diabetic ob/ob mice.
Volume: 248
Issue: 2
Pages: 85-8
Publication
First Author: Heep H
Year: 2008
Journal: Int J Biol Sci
Title: Differences in trabecular bone of leptin-deficient ob/ob mice in response to biomechanical loading.
Volume: 4
Issue: 3
Pages: 169-75
Publication
First Author: Seemann R
Year: 2018
Journal: J Musculoskelet Neuronal Interact
Title: Leptin-deficiency eradicates the positive effect of traumatic brain injury on bone healing: histological analyses in a combined trauma mouse model.
Volume: 18
Issue: 1
Pages: 32-41
Publication
First Author: Duong M
Year: 2018
Journal: PLoS One
Title: Induction of obesity impairs reverse cholesterol transport in ob/ob mice.
Volume: 13
Issue: 9
Pages: e0202102
Publication
First Author: Melia HP
Year: 1999
Journal: FEBS Lett
Title: Effects of acute leptin administration on the differences in proton leak rate in liver mitochondria from ob/ob mice compared to lean controls.
Volume: 458
Issue: 2
Pages: 261-4
Publication
First Author: Inami Y
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression.
Volume: 412
Issue: 4
Pages: 618-25
Publication
First Author: Ravussin Y
Year: 2018
Journal: Cell Metab
Title: Evidence for a Non-leptin System that Defends against Weight Gain in Overfeeding.
Volume: 28
Issue: 2
Pages: 289-299.e5
Publication
First Author: Nadler ST
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The expression of adipogenic genes is decreased in obesity and diabetes mellitus.
Volume: 97
Issue: 21
Pages: 11371-6
Publication
First Author: Deem JD
Year: 2018
Journal: Am J Physiol Endocrinol Metab
Title: Leptin regulation of core body temperature involves mechanisms independent of the thyroid axis.
Volume: 315
Issue: 4
Pages: E552-E564
Publication
First Author: Almeida YE
Year: 2020
Journal: Sci Rep
Title: Excessive cholecalciferol supplementation increases kidney dysfunction associated with intrarenal artery calcification in obese insulin-resistant mice.
Volume: 10
Issue: 1
Pages: 87
Publication
First Author: Sasaki M
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Sulforaphane promotes murine hair growth by accelerating the degradation of dihydrotestosterone.
Volume: 472
Issue: 1
Pages: 250-4
Publication  
First Author: Bühler D
Year: 2023
Journal: Front Neurosci
Title: Leptin deficiency-caused behavioral change - A comparative analysis using EthoVision and DeepLabCut.
Volume: 17
Pages: 1052079