Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang E |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress. |
Volume: |
8 |
Issue: |
1 |
Pages: |
1399 |
|
•
•
•
•
•
|
Publication |
First Author: |
Endele S |
Year: |
1999 |
Journal: |
Genomics |
Title: |
LETM1, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, flanks the Wolf-Hirschhorn syndrome (WHS) critical region and is deleted in most WHS patients. |
Volume: |
60 |
Issue: |
2 |
Pages: |
218-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Snyder MM |
Year: |
2021 |
Journal: |
FASEB J |
Title: |
LETMD1 is required for mitochondrial structure and thermogenic function of brown adipocytes. |
Volume: |
35 |
Issue: |
11 |
Pages: |
e21965 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shao J |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Leucine zipper-EF-hand containing transmembrane protein 1 (LETM1) forms a Ca2+/H+ antiporter. |
Volume: |
6 |
|
Pages: |
34174 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang D |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Letm1, the mitochondrial Ca2+/H+ antiporter, is essential for normal glucose metabolism and alters brain function in Wolf-Hirschhorn syndrome. |
Volume: |
110 |
Issue: |
24 |
Pages: |
E2249-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kuum M |
Year: |
2012 |
Journal: |
J Cell Sci |
Title: |
Endoplasmic reticulum potassium-hydrogen exchanger and small conductance calcium-activated potassium channel activities are essential for ER calcium uptake in neurons and cardiomyocytes. |
Volume: |
125 |
Issue: |
Pt 3 |
Pages: |
625-33 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7580628 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603921 |
Pattern: |
Ubiquitous |
Stage: |
TS21 |
Assay Id: |
MGI:7580631 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
3b |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3527622 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-02-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1674419 |
|
Stage: |
TS19 |
Assay Id: |
MGI:3527623 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
E11.5 mesonephros |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7580628 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684621 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:7580631 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
3b |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3527622 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-02-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1636715 |
|
Stage: |
TS15 |
Assay Id: |
MGI:3527623 |
Age: |
embryonic day 9.5 |
|
Note: |
There is no expression present in the urogenital ridge. |
Specimen Label: |
E9.5 urogenital ridge |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3527622 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-02-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1868522 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:3527623 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression is present in the testis cords. |
Specimen Label: |
E14.5 testis |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3527622 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-02-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1738319 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:3527623 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
E11.5 genital ridge |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7580628 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:7580631 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
3b |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3527622 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-02-25 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:1796222 |
|
Stage: |
TS22 |
Assay Id: |
MGI:3527623 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
E14.5 ovary |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Osada N |
Year: |
2000 |
Journal: |
GenBank Submission |
Title: |
Mus musculus brain cDNA, clone MNCb-2242, similar to Mus musculus leucine zipper-EF-hand containing transmembrane protein 1 (Letm1) mRNA |
|
|
Pages: |
AB041582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Näf D |
Year: |
2001 |
Journal: |
Hum Mol Genet |
Title: |
Mouse models for the Wolf-Hirschhorn deletion syndrome. |
Volume: |
10 |
Issue: |
2 |
Pages: |
91-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chern T |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. |
Volume: |
13 |
Issue: |
1 |
Pages: |
134 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang D |
Year: |
2024 |
Journal: |
J Cell Physiol |
Title: |
Maternal Ezh1/2 deficiency impairs the function of mitochondria in mouse oocytes and early embryos. |
Volume: |
239 |
Issue: |
6 |
Pages: |
e31244 |
|
•
•
•
•
•
|
Publication |
First Author: |
Meng TG |
Year: |
2023 |
Journal: |
Adv Sci (Weinh) |
Title: |
NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte-to-Embryo Transition. |
Volume: |
10 |
Issue: |
27 |
Pages: |
e2301940 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pagliarini DJ |
Year: |
2008 |
Journal: |
Cell |
Title: |
A mitochondrial protein compendium elucidates complex I disease biology. |
Volume: |
134 |
Issue: |
1 |
Pages: |
112-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Georgas K |
Year: |
2009 |
Journal: |
Dev Biol |
Title: |
Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. |
Volume: |
332 |
Issue: |
2 |
Pages: |
273-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wertz K |
Year: |
2000 |
Journal: |
Mech Dev |
Title: |
Large-scale screen for genes involved in gonad development. |
Volume: |
98 |
Issue: |
1-2 |
Pages: |
51-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Da Cruz S |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Proteomic analysis of the mouse liver mitochondrial inner membrane. |
Volume: |
278 |
Issue: |
42 |
Pages: |
41566-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mootha VK |
Year: |
2003 |
Journal: |
Cell |
Title: |
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. |
Volume: |
115 |
Issue: |
5 |
Pages: |
629-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
|
Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
480
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
LETM1 domain-containing protein 1 |
Type: |
chain |
End: |
360 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakamura S |
Year: |
2020 |
Journal: |
Commun Biol |
Title: |
The mitochondrial inner membrane protein LETM1 modulates cristae organization through its LETM domain. |
Volume: |
3 |
Issue: |
1 |
Pages: |
99 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
360
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiao H |
Year: |
2022 |
Journal: |
Cell |
Title: |
Architecture of the outbred brown fat proteome defines regulators of metabolic physiology. |
Volume: |
185 |
Issue: |
24 |
Pages: |
4654-4673.e28 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
26 |
Description: |
LETM1 domain-containing protein LETM2, mitochondrial |
Type: |
chain |
End: |
480 |
|
•
•
•
•
•
|
Allele |
Name: |
LETM1 domain containing 1; endonuclease-mediated mutation 1, Shihuan Kuang |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
221
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
288
 |
Fragment?: |
false |
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Gene |
Type: |
gene |
Organism: |
frog, African clawed |
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Gene |
Type: |
gene |
Organism: |
frog, African clawed |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
171
 |
Fragment?: |
false |
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•
•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
196
 |
Fragment?: |
false |
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•
•
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