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Search results 1 to 100 out of 147 for Maf1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
84232 | MAF1
Type: gene
Organism: human
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Gene
733512 | maf1
Type: gene
Organism: frog, western clawed
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Gene
100857613 | MAF1
Type: gene
Organism: chicken
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Gene
315093 | Maf1
Type: gene
Organism: rat
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Gene
464456 | MAF1
Type: gene
Organism: chimpanzee
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Gene
482087 | MAF1
Type: gene
Organism: dog, domestic
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Gene
512498 | MAF1
Type: gene
Organism: cattle
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Gene
700385 | MAF1
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR015257 | Maf1
Type: Family
Description: Maf1 is a negative regulator of RNA polymerase III [, ]. It inhibits the de novo assembly of TFIIIB onto DNA []. Maf1 represses Pol III in response to DNA damage, oxidative stress, growth to stationary phase, treatment with rapamycin or chlorpromazine, and blocking of the secretory pathway []. It targets the initiation factor TFIIIB []. Its structure has been solved [].
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Protein Coding Gene
MGI:1916127 | Maf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25934505 | J:222253
First Author: Bonhoure N
Year: 2015
Journal: Genes Dev
Title: Loss of the RNA polymerase III repressor MAF1 confers obesity resistance.
Volume: 29
Issue: 9
Pages: 934-47
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Publication
32686713 | J:294203
First Author: Bonhoure N
Year: 2020
Journal: Sci Rep
Title: MAF1 is a chronic repressor of RNA polymerase III transcription in the mouse.
Volume: 10
Issue: 1
Pages: 11956
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Protein
E0CYF5
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: false
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Protein
Q9D0U6
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: false
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Protein
E0CYK4
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
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Publication
30429315 | J:269014
First Author: Willis IM
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Metabolic programming a lean phenotype by deregulation of RNA polymerase III.
Volume: 115
Issue: 48
Pages: 12182-12187
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Publication
38143800 | J:344230
 
First Author: Willemin G
Year: 2023
Journal: Front Mol Biosci
Title: Contrasting effects of whole-body and hepatocyte-specific deletion of the RNA polymerase III repressor Maf1 in the mouse.
Volume: 10
Pages: 1297800
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Publication
12504022 | -
First Author: Upadhya R
Year: 2002
Journal: Mol Cell
Title: Maf1 is an essential mediator of diverse signals that repress RNA polymerase III transcription.
Volume: 10
Issue: 6
Pages: 1489-94
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Publication
17785443 | -
First Author: Cieśla M
Year: 2007
Journal: Mol Cell Biol
Title: Maf1 is involved in coupling carbon metabolism to RNA polymerase III transcription.
Volume: 27
Issue: 21
Pages: 7693-702
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Publication
38226680 | J:350727
First Author: Han Y
Year: 2024
Journal: Brain
Title: Maf1 loss regulates spinogenesis and attenuates cognitive impairment in Alzheimer's disease.
Volume: 147
Issue: 6
Pages: 2128-2143
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Publication
18377933 | J:170798
First Author: Goodfellow SJ
Year: 2008
Journal: J Mol Biol
Title: Regulation of RNA polymerase III transcription by Maf1 in mammalian cells.
Volume: 378
Issue: 3
Pages: 481-91
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Publication
31695767 | J:294677
First Author: Sun Y
Year: 2019
Journal: Theranostics
Title: Maf1 ameliorates cardiac hypertrophy by inhibiting RNA polymerase III through ERK1/2.
Volume: 9
Issue: 24
Pages: 7268-7281
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Publication
34902358 | J:319889
 
First Author: Chen D
Year: 2022
Journal: Exp Neurol
Title: Maf1 regulates axonal regeneration of retinal ganglion cells after injury.
Volume: 348
Pages: 113948
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Gene
391578 | MAF1P1
Type: gene
Organism: human
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Publication
20543138 | J:175339
First Author: Kantidakis T
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1.
Volume: 107
Issue: 26
Pages: 11823-8
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Publication
25502566 | J:222654
First Author: Palian BM
Year: 2014
Journal: PLoS Genet
Title: Maf1 is a novel target of PTEN and PI3K signaling that negatively regulates oncogenesis and lipid metabolism.
Volume: 10
Issue: 12
Pages: e1004789
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Publication
11438659 | -
First Author: Pluta K
Year: 2001
Journal: Mol Cell Biol
Title: Maf1p, a negative effector of RNA polymerase III in Saccharomyces cerevisiae.
Volume: 21
Issue: 15
Pages: 5031-40
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Publication
20887893 | -
First Author: Vannini A
Year: 2010
Journal: Cell
Title: Molecular basis of RNA polymerase III transcription repression by Maf1.
Volume: 143
Issue: 1
Pages: 59-70
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Publication
16762835 | -
First Author: Oficjalska-Pham D
Year: 2006
Journal: Mol Cell
Title: General repression of RNA polymerase III transcription is triggered by protein phosphatase type 2A-mediated dephosphorylation of Maf1.
Volume: 22
Issue: 5
Pages: 623-32
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Publication
15196897 | -
 
First Author: Willis IM
Year: 2004
Journal: Prog Nucleic Acid Res Mol Biol
Title: Signaling repression of transcription by RNA polymerase III in yeast.
Volume: 77
Pages: 323-53
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Publication
38089586 | J:343468
First Author: Li Y
Year: 2023
Journal: iScience
Title: Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms.
Volume: 26
Issue: 12
Pages: 108544
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Publication
35611941 | J:341503
   
First Author: Phillips E
Year: 2022
Journal: Elife
Title: MAF1, a repressor of RNA polymerase III-dependent transcription, regulates bone mass.
Volume: 11
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Publication
20516213 | J:162787
First Author: Michels AA
Year: 2010
Journal: Mol Cell Biol
Title: mTORC1 directly phosphorylates and regulates human MAF1.
Volume: 30
Issue: 15
Pages: 3749-57
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Protein Coding Gene
MGP_CAROLIEiJ_G0019923 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021987 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021945 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021928 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021954 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021726 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1916127 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0022394 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0021245 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021693 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021818 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021799 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021889 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021823 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0022414 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020986 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0021297 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019933 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020826 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716824
Pattern: Uniform
Stage: TS24
Assay Id: MGI:3585533
Age: embryonic day 16.0
Image: E16
Note: Expression was panretinal.
Specimen Label: E16
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585533
Age: postnatal day 6-7
Image: P6/7
Note: Expression was panretinal, but the level was higher in amacrine and ganglion cells.
Specimen Label: P6/7
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585533
Age: postnatal day 0-1
Image: P0/1
Note: Expression was detected in the inner neuroblastic layer.
Specimen Label: P0/1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585533
Age: postnatal adult
Image: Adult
Specimen Label: Adult
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3585533
Age: embryonic day 16.0
Specimen Label: Embryo
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3585533
Age: embryonic day 18.0
Image: E18
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E18
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585533
Age: postnatal day 0-1
Image: P0/1
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P0/1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585533
Age: postnatal day 2-3
Image: P2/3
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585533
Age: postnatal adult
Image: Adult
Specimen Label: Adult
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3585533
Age: embryonic day 16.0
Note: Expression was detected in Kuffler cells (resident hepatic macrophages).
Specimen Label: Embryo
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3585533
Age: embryonic day 16.0
Specimen Label: Embryo
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585533
Age: postnatal day 8-10
Image: P8/10
Note: Expression was detected in amacrine cells.
Specimen Label: P8/10
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585533
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:3584905
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3585533
Age: embryonic day 14.0
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E14
Detected: true
Specimen Num: 1
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Allele
Maf1<em1Lnh> | MGI:5661490
Name: MAF1 homolog, negative regulator of RNA polymerase III; endonuclease-mediated mutation 1, Nouria Hernandez
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Maf1<tm1Lnh> | MGI:7645448
Name: MAF1 homolog, negative regulator of RNA polymerase III; targeted mutation 1, Nouria Hernandez
Allele Type: Targeted
Attribute String: Conditional ready
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
29248739 | J:261856
First Author: Willis IM
Year: 2018
Journal: Biochim Biophys Acta
Title: Maf1 phenotypes and cell physiology.
Volume: 1861
Issue: 4
Pages: 330-337
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