| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Melan-A, also known as melanoma antigen recognised by T-cells 1, or MART-1, is a protein that in humans is encoded by the MLANA gene. It is required for the function of the melanosomal matrix protein PMEL17/GP100 and thus plays an important role in regulating mammalian pigmentation []. Melan-A is a member of the MAGE gene family []and is a tumour associated antigen. Clinically, the protein may serve as an anti-cancer vaccine []. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
113
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
113
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hoashi T |
| Year: |
2005 |
| Journal: |
J Biol Chem |
| Title: |
MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes. |
| Volume: |
280 |
| Issue: |
14 |
| Pages: |
14006-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bardliving CL |
| Year: |
2013 |
| Journal: |
Protein Expr Purif |
| Title: |
Process development and production of cGMP grade Melan-A for cancer vaccine clinical trials. |
| Volume: |
92 |
| Issue: |
2 |
| Pages: |
171-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chomez P |
| Year: |
2001 |
| Journal: |
Cancer Res |
| Title: |
An overview of the MAGE gene family with the identification of all human members of the family. |
| Volume: |
61 |
| Issue: |
14 |
| Pages: |
5544-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aydin IT |
| Year: |
2011 |
| Journal: |
Genesis |
| Title: |
A mart-1::Cre transgenic line induces recombination in melanocytes and retinal pigment epithelium. |
| Volume: |
49 |
| Issue: |
5 |
| Pages: |
403-9 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouriaux F |
| Year: |
2016 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Effects of Long-term Serial Passaging on the Characteristics and Properties of Cell Lines Derived From Uveal Melanoma Primary Tumors. |
| Volume: |
57 |
| Issue: |
13 |
| Pages: |
5288-5301 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619819 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
3 C57BL/6J |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619819 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
3 Mitf Mi/+ |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619819 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
3 Mitf Mi/Mi |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619819 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
| Image: |
sl_Mlana_+_+_a_head_40 |
|
| Specimen Label: |
sl_Mlana_+_+_a_head_40 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619819 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
| Image: |
sl_Mlana_mi_+_a_head_40 |
|
| Specimen Label: |
sl_Mlana_mi_+_a_head_40 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619819 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
| Image: |
sl_Mlana_mi_mi_a_head_40 |
|
| Specimen Label: |
sl_Mlana_mi_mi_a_head_40 |
| Detected: |
false |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619819 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
| Image: |
sl_MlanA_mi_mi_a_side_16 |
|
| Specimen Label: |
sl_MlanA_mi_mi_a_side_16 |
| Detected: |
false |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619819 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
| Image: |
sl_MlnA_mi_+_a_side_16 |
|
| Specimen Label: |
sl_MlnA_mi_+_a_side_16 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619819 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
| Image: |
sl_MlanA_+_+_a_side_16 |
|
| Specimen Label: |
sl_MlanA_+_+_a_side_16 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717219 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
5A Mitf+/+ |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717219 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
5A Mitf Mi/+ |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717219 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
5A Mitf Mi/Mi |
| Detected: |
false |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1616919 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
| Image: |
sl_Mlana_+_+_a_head_40 |
| Note: |
Absent in melanoblasts. |
| Specimen Label: |
sl_Mlana_+_+_a_head_40 |
| Detected: |
false |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1616919 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
| Image: |
sl_Mlana_mi_+_a_head_40 |
| Note: |
Absent in melanoblasts. |
| Specimen Label: |
sl_Mlana_mi_+_a_head_40 |
| Detected: |
false |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1616919 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
| Image: |
sl_Mlana_mi_mi_a_head_40 |
| Note: |
Absent in melanoblasts. |
| Specimen Label: |
sl_Mlana_mi_mi_a_head_40 |
| Detected: |
false |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6456179 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-09-21 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3639228 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6456591 |
| Age: |
postnatal adult |
| Image: |
3H (Late) |
| Note: |
Abnormal increase in density in dermis in locations concurrent with increased incidence of pigment. |
| Specimen Label: |
3H (Late) |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3273519 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Absent in melanoblasts. |
| Specimen Label: |
3 C57BL/6J |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3273519 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Absent in melanoblasts. |
| Specimen Label: |
3 Mitf Mi/+ |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3273519 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
3 Mitf Mi/Mi |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3273519 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
| Image: |
sl_MlanA_+_+_a_side_16 |
| Note: |
Absent in melanoblasts. |
| Specimen Label: |
sl_MlanA_+_+_a_side_16 |
| Detected: |
false |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3273519 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
| Image: |
sl_MlanA_mi_mi_a_side_16 |
| Note: |
Absent in melanoblasts. |
| Specimen Label: |
sl_MlanA_mi_mi_a_side_16 |
| Detected: |
false |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4437036 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-03-11 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3273519 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:4437035 |
| Age: |
embryonic day 11.5 |
| Image: |
sl_MlnA_mi_+_a_side_16 |
| Note: |
Absent in melanoblasts. |
| Specimen Label: |
sl_MlnA_mi_+_a_side_16 |
| Detected: |
false |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6456179 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752728 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:6456591 |
| Age: |
postnatal adult |
| Image: |
3H +/+ |
| Note: |
Expression in dermal melanocytes. |
| Specimen Label: |
3H +/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6456179 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-09-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6456591 |
| Age: |
postnatal adult |
| Image: |
3H (Early) |
|
| Specimen Label: |
3H (Early) |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aydin IT |
| Year: |
2012 |
| Journal: |
Pigment Cell Melanoma Res |
| Title: |
Coat color dilution in mice because of inactivation of the melanoma antigen MART-1. |
| Volume: |
25 |
| Issue: |
1 |
| Pages: |
37-46 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Giordano F |
| Year: |
2009 |
| Journal: |
Hum Mol Genet |
| Title: |
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| Allele |
| Name: |
melan-A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
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| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
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| Allele |
| Name: |
transgene insertion 5, Friedrich Beermann |
| Allele Type: |
Transgenic |
| Attribute String: |
Recombinase |
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