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Search results 1 to 100 out of 1376 for Mycn

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Hits by Strain

Type Details Score
Gene
4613 | MYCN
Type: gene
Organism: human
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Gene
448649 | mycn
Type: gene
Organism: frog, western clawed
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Gene
298894 | Mycn
Type: gene
Organism: rat
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Gene
482978 | MYCN
Type: gene
Organism: dog, domestic
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Gene
459043 | MYCN
Type: gene
Organism: chimpanzee
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Gene
616888 | MYCN
Type: gene
Organism: cattle
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Gene
252851 | mycn
Type: gene
Organism: zebrafish
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Gene
698699 | MYCN
Type: gene
Organism: macaque, rhesus
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Gene
key_80056 | MYCN
Type: gene
Organism: cat, domestic
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Gene
key_25168 | MYCN
Type: gene
Organism: sheep
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Gene
421948 | MYCN
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:97357 | Mycn
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
10408 | MYCNOS
Type: gene
Organism: human
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Gene
103752554 | MYCNUT
Type: gene
Organism: human
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Publication
20478998 | J:160518
First Author: Swartling FJ
Year: 2010
Journal: Genes Dev
Title: Pleiotropic role for MYCN in medulloblastoma.
Volume: 24
Issue: 10
Pages: 1059-72
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Publication
22218692 | J:183718
First Author: Chanthery YH
Year: 2012
Journal: Sci Transl Med
Title: Paracrine signaling through MYCN enhances tumor-vascular interactions in neuroblastoma.
Volume: 4
Issue: 115
Pages: 115ra3
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Publication
34625907 | J:353394
First Author: Chen J
Year: 2022
Journal: Mol Neurobiol
Title: Function of Oncogene Mycn in Adult Neurogenesis and Oligodendrogenesis.
Volume: 59
Issue: 1
Pages: 77-92
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Publication
28459463 | J:247891
First Author: Olsen RR
Year: 2017
Journal: Oncogene
Title: MYCN induces neuroblastoma in primary neural crest cells.
Volume: 36
Issue: 35
Pages: 5075-5082
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Publication
23063798 | J:190992
First Author: Harmelink C
Year: 2013
Journal: Dev Biol
Title: Myocardial Mycn is essential for mouse ventricular wall morphogenesis.
Volume: 373
Issue: 1
Pages: 53-63
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Publication
22789543 | J:191012
First Author: Berry T
Year: 2012
Journal: Cancer Cell
Title: The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma.
Volume: 22
Issue: 1
Pages: 117-30
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Publication
16912192 | J:112163
First Author: Chesler L
Year: 2006
Journal: Cancer Res
Title: Inhibition of phosphatidylinositol 3-kinase destabilizes Mycn protein and blocks malignant progression in neuroblastoma.
Volume: 66
Issue: 16
Pages: 8139-46
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Publication
29636449 | J:261937
First Author: Mirzamohammadi F
Year: 2018
Journal: Nat Commun
Title: Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models.
Volume: 9
Issue: 1
Pages: 1352
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Publication
25171250 | J:242189
First Author: DeWitt J
Year: 2014
Journal: Dev Neurosci
Title: Ciliary neurotrophic factor reduces the proliferation and promotes the differentiation of TH- MYCN transformed sympathoadrenal progenitors.
Volume: 36
Issue: 5
Pages: 422-31
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Publication
19208763 | J:146444
First Author: Alvarez-Rodríguez R
Year: 2009
Journal: J Cell Sci
Title: Expression of the proneural gene encoding Mash1 suppresses MYCN mitotic activity.
Volume: 122
Issue: Pt 5
Pages: 595-9
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190832
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Mycn
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190832
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Mycn
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190832
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Mycn
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190832
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Mycn
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190832
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Mycn
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190832
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Mycn
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190832
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Mycn
Detected: true
Specimen Num: 7
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Publication
34590686 | J:326460
First Author: Yang R
Year: 2022
Journal: Hum Mol Genet
Title: Mycn deficiency underlies the development of orofacial clefts in mice and humans.
Volume: 31
Issue: 5
Pages: 803-815
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Publication
33387268 | J:332187
First Author: Holdhof D
Year: 2021
Journal: Cerebellum
Title: Simultaneous Brg1 Knockout and MYCN Overexpression in Cerebellar Granule Neuron Precursors Is Insufficient to Drive Tumor Formation but Temporarily Enhances their Proliferation and Delays their Migration.
Volume: 20
Issue: 3
Pages: 410-419
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GXD Expression
GXD Expression
 
Probe: MGI:7738626
Assay Type: RNA in situ
Annotation Date: 2024-10-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3540017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7750770
Age: embryonic day 10.5
Note: Expression of the proliferation marker Mycn was detected in the interventricular septum.
Specimen Label: S1D WT
Detected: true
Specimen Num: 1
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DO Term
DOID:0080888 | spinal ependymoma, MYCN-amplified
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Publication
32820040 | J:303705
First Author: Grunblatt E
Year: 2020
Journal: Genes Dev
Title: MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity.
Volume: 34
Issue: 17-18
Pages: 1210-1226
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GXD Expression
GXD Expression
 
Probe: MGI:7738626
Assay Type: RNA in situ
Annotation Date: 2024-10-22
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3540017
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7750770
Age: embryonic day 10.5
Note: Expression of the proliferation marker Mycn was lower in the interventricular septum of the mutant compared with wild type.
Specimen Label: S1D Chd4
Detected: true
Specimen Num: 2
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Protein
Q810L7
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
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Gene
100609397 | MYCNOS
Type: gene
Organism: chimpanzee
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Publication
30573562 | J:271076
     
First Author: Kato K
Year: 2018
Journal: J Med Genet
Title: MYCN de novo gain-of-function mutation in a patient with a novel megalencephaly syndrome.
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Publication
25785590 | J:233439
First Author: Ahmad Z
Year: 2015
Journal: PLoS One
Title: Molecular and in vivo characterization of cancer-propagating cells derived from MYCN-dependent medulloblastoma.
Volume: 10
Issue: 3
Pages: e0119834
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Publication
22624711 | J:189301
First Author: Swartling FJ
Year: 2012
Journal: Cancer Cell
Title: Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.
Volume: 21
Issue: 5
Pages: 601-13
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Publication
22340587 | J:181466
First Author: Hogarty MD
Year: 2012
Journal: Cancer Cell
Title: PI3King on MYCN to improve neuroblastoma therapeutics.
Volume: 21
Issue: 2
Pages: 145-7
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Publication
20153925 | J:164102
First Author: Bell E
Year: 2010
Journal: Cancer Lett
Title: MYCN oncoprotein targets and their therapeutic potential.
Volume: 293
Issue: 2
Pages: 144-57
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Publication
28165337 | J:240402
First Author: Wu N
Year: 2017
Journal: J Clin Invest
Title: A mouse model of MYCN-driven retinoblastoma reveals MYCN-independent tumor reemergence.
Volume: 127
Issue: 3
Pages: 888-898
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Publication
32595833 | J:310037
First Author: Yang CL
Year: 2020
Journal: Oncotarget
Title: Lineage-restricted sympathoadrenal progenitors confer neuroblastoma origin and its tumorigenicity.
Volume: 11
Issue: 24
Pages: 2357-2371
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Publication
21849159 | J:178560
First Author: Westermark UK
Year: 2011
Journal: Semin Cancer Biol
Title: The MYCN oncogene and differentiation in neuroblastoma.
Volume: 21
Issue: 4
Pages: 256-66
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Publication
39402275 | J:357531
First Author: Cheung BB
Year: 2024
Journal: Commun Biol
Title: Golgi-localized Ring Finger Protein 121 is necessary for MYCN-driven neuroblastoma tumorigenesis.
Volume: 7
Issue: 1
Pages: 1322
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Publication
36734327 | J:338272
 
First Author: Sendra M
Year: 2023
Journal: Development
Title: Cre recombinase microinjection for single-cell tracing and localised gene targeting.
Volume: 150
Issue: 3
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Publication
33804256 | J:305117
 
First Author: Jiao X
Year: 2021
Journal: Int J Mol Sci
Title: Reduced Granule Cell Proliferation and Molecular Dysregulation in the Cerebellum of Lysosomal Acid Phosphatase 2 (ACP2) Mutant Mice.
Volume: 22
Issue: 6
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Publication
27773673 | J:249255
First Author: Xiao D
Year: 2016
Journal: Mol Cell
Title: Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
Volume: 64
Issue: 3
Pages: 493-506
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Publication
27668798 | J:258583
First Author: King B
Year: 2016
Journal: Nat Immunol
Title: The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells.
Volume: 17
Issue: 11
Pages: 1312-1321
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Publication
25557119 | J:278563
First Author: Nakaguro M
Year: 2015
Journal: Cancer Sci
Title: Nucleolar protein PES1 is a marker of neuroblastoma outcome and is associated with neuroblastoma differentiation.
Volume: 106
Issue: 3
Pages: 237-43
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Publication
26829053 | J:230720
First Author: Ueda T
Year: 2016
Journal: Oncogene
Title: ALK(R1275Q) perturbs extracellular matrix, enhances cell invasion and leads to the development of neuroblastoma in cooperation with MYCN.
Volume: 35
Issue: 34
Pages: 4447-58
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Publication
22921766 | J:192942
First Author: Valli E
Year: 2012
Journal: Biochim Biophys Acta
Title: CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells.
Volume: 1819
Issue: 11-12
Pages: 1173-85
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Publication
27728805 | J:236713
First Author: Dardenne E
Year: 2016
Journal: Cancer Cell
Title: N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
Volume: 30
Issue: 4
Pages: 563-577
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Publication
27618649 | J:240517
First Author: Tavana O
Year: 2016
Journal: Nat Med
Title: HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.
Volume: 22
Issue: 10
Pages: 1180-1186
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Publication
20537458 | J:161374
First Author: Varlakhanova NV
Year: 2010
Journal: Differentiation
Title: myc maintains embryonic stem cell pluripotency and self-renewal.
Volume: 80
Issue: 1
Pages: 9-19
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Publication
- | J:14305
 
First Author: Klett C
Year: 1991
Journal: Mouse Genome
Title: Mapping of Nmyc-1 to mouse Chromosome 12, band A3/B.
Volume: 89
Pages: 275
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Publication
22164278 | J:182261
First Author: Terrile M
Year: 2011
Journal: PLoS One
Title: miRNA expression profiling of the murine TH-MYCN neuroblastoma model reveals similarities with human tumors and identifies novel candidate miRNAs.
Volume: 6
Issue: 12
Pages: e28356
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Publication
22907436 | J:199983
First Author: Calao M
Year: 2013
Journal: Oncogene
Title: Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation.
Volume: 32
Issue: 31
Pages: 3616-26
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Publication
33410138 | J:304357
First Author: Seya D
Year: 2021
Journal: Dev Growth Differ
Title: A role of Hey2 transcription factor for right ventricle development through regulation of Tbx2-Mycn pathway during cardiac morphogenesis.
Volume: 63
Issue: 1
Pages: 82-92
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Publication
30642836 | J:272568
 
First Author: Muñoz-Martín N
Year: 2019
Journal: Development
Title: Myc is dispensable for cardiomyocyte development but rescues Mycn-deficient hearts through functional replacement and cell competition.
Volume: 146
Issue: 3
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Publication
30061166 | J:270575
 
First Author: Mastromina I
Year: 2018
Journal: Development
Title: Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse.
Volume: 145
Issue: 14
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Publication
23430699 | J:198307
First Author: Puissant A
Year: 2013
Journal: Cancer Discov
Title: Targeting MYCN in neuroblastoma by BET bromodomain inhibition.
Volume: 3
Issue: 3
Pages: 308-23
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Publication
31042497 | J:278332
First Author: Sun Q
Year: 2019
Journal: Dev Biol
Title: SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.
Volume: 452
Issue: 1
Pages: 1-7
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Publication
34716243 | J:330416
First Author: Li J
Year: 2021
Journal: J Am Soc Nephrol
Title: Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance.
Volume: 32
Issue: 11
Pages: 2815-2833
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Publication
21307096 | J:170488
First Author: Blank MC
Year: 2011
Journal: Development
Title: Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis.
Volume: 138
Issue: 6
Pages: 1207-16
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Publication
25175806 | J:214800
First Author: Gustafson WC
Year: 2014
Journal: Cancer Cell
Title: Drugging MYCN through an allosteric transition in Aurora kinase A.
Volume: 26
Issue: 3
Pages: 414-427
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Protein Coding Gene
MGP_CAROLIEiJ_G0017621 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019604 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019570 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019541 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97357 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019995 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018907 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019323 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019436 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019427 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019507 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019461 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020034 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018673 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018958 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029377 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018463 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
3513190 | J:8219
First Author: DePinho RA
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: Structure and expression of the murine N-myc gene.
Volume: 83
Issue: 6
Pages: 1827-31
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Publication
3015591 | J:8353
First Author: Taya Y
Year: 1986
Journal: EMBO J
Title: Nucleotide sequence of the coding region of the mouse N-myc gene.
Volume: 5
Issue: 6
Pages: 1215-9
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Publication
3287334 | J:9196
First Author: Katoh K
Year: 1988
Journal: Nucleic Acids Res
Title: Complete nucleotide sequence and exon-intron boundaries of the 5' non-coding region of the mouse N-myc gene.
Volume: 16
Issue: 8
Pages: 3589
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Publication
9635194 | J:67930
First Author: Nagy A
Year: 1998
Journal: Curr Biol
Title: Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles.
Volume: 8
Issue: 11
Pages: 661-4
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Publication
1701023 | J:48400
First Author: Stanton BR
Year: 1990
Journal: Mol Cell Biol
Title: Germ line transmission of an inactive N-myc allele generated by homologous recombination in mouse embryonic stem cells.
Volume: 10
Issue: 12
Pages: 6755-8
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Publication
10837121 | J:107691
First Author: Bates CM
Year: 2000
Journal: Dev Biol
Title: Role of N-myc in the developing mouse kidney.
Volume: 222
Issue: 2
Pages: 317-25
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Publication
1459450 | J:3413
First Author: Charron J
Year: 1992
Journal: Genes Dev
Title: Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene.
Volume: 6
Issue: 12A
Pages: 2248-57
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Publication
1577267 | J:973
First Author: Moens CB
Year: 1992
Journal: Genes Dev
Title: A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung.
Volume: 6
Issue: 5
Pages: 691-704
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Publication
17486137 | J:355764
 
First Author: Cox B
Year: 2007
Journal: Mol Syst Biol
Title: Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes.
Volume: 3
Pages: 109
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Publication
1931830 | J:76279
First Author: Sawai S
Year: 1991
Journal: New Biol
Title: Embryonic lethality resulting from disruption of both N-myc alleles in mouse zygotes.
Volume: 3
Issue: 9
Pages: 861-9
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Publication
8404543 | J:11859
First Author: Sawai S
Year: 1993
Journal: Development
Title: Defects of embryonic organogenesis resulting from targeted disruption of the N-myc gene in the mouse.
Volume: 117
Issue: 4
Pages: 1445-55
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Publication
20530674 | J:161601
First Author: Heine VM
Year: 2010
Journal: Cancer Res
Title: Dexamethasone destabilizes Nmyc to inhibit the growth of hedgehog-associated medulloblastoma.
Volume: 70
Issue: 13
Pages: 5220-5
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