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Search results 1 to 100 out of 483 for Myocd

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
93649 | MYOCD
Type: gene
Organism: human
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Gene
100498057 | myocd
Type: gene
Organism: frog, western clawed
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Gene
246297 | Myocd
Type: gene
Organism: rat
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Gene
455063 | MYOCD
Type: gene
Organism: chimpanzee
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Gene
489509 | MYOCD
Type: gene
Organism: dog, domestic
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Gene
539517 | MYOCD
Type: gene
Organism: cattle
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Gene
427790 | MYOCD
Type: gene
Organism: chicken
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Gene
100331725 | myocd
Type: gene
Organism: zebrafish
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Gene
718193 | MYOCD
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR028721 | MYOCD
Type: Family
Description: Myocardin (Myocd) is a coactivator of serum response factor (SRF), which is a key regulator of the expression of smooth and cardiac muscle genes. Myocardin plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis) [, ]. It contains the RPEL repeats, which are monomeric globular actin (G-actin) binding elements. However, it binds to actin-related protein 5 (Arp5) instead of conventional actin, resulting in a significant suppression of Myocd activity [].
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Protein Coding Gene
MGI:2137495 | Myocd
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
B9EJ16
Organism: Mus musculus/domesticus
Length: 948  
Fragment?: false
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Publication
12640126 | J:82506
First Author: Du KL
Year: 2003
Journal: Mol Cell Biol
Title: Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation.
Volume: 23
Issue: 7
Pages: 2425-37
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Gene
101928418 | MYOCD-AS1
Type: gene
Organism: human
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GXD Expression
GXD Expression
     
Probe: MGI:4949079
Assay Type: RT-PCR
Annotation Date: 2011-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:4949210
Age: embryonic day 8.25
Specimen Label: Myocd Sox17+/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4949079
Assay Type: RT-PCR
Annotation Date: 2011-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:4949210
Age: embryonic day 8.25
Specimen Label: Myocd Sox17-/-
Detected: true
Specimen Num: 2
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Publication
36484734 | J:340976
First Author: Yang Q
Year: 2023
Journal: J Pathol
Title: Myocd regulates airway smooth muscle cell remodeling in response to chronic asthmatic injury.
Volume: 259
Issue: 3
Pages: 331-341
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Gene
100128006 | ARHGAP44-AS1
Type: gene
Organism: human
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Protein
F6TBX6
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: true
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Protein
Q3US93
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: true
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Publication
24025544 | -
First Author: Long X
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Myocardin: new therapeutic agent in vascular disease?
Volume: 33
Issue: 10
Pages: 2284-5
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Publication
24567363 | -
First Author: Morita T
Year: 2014
Journal: J Cell Biol
Title: Arp5 is a key regulator of myocardin in smooth muscle cells.
Volume: 204
Issue: 5
Pages: 683-96
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Publication
35905011 | J:327332
 
First Author: Kurz J
Year: 2022
Journal: Development
Title: GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter.
Volume: 149
Issue: 15
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Publication
38014633 | J:343799
 
First Author: Katano W
Year: 2023
Journal: Development
Title: Sall1 and Sall4 cooperatively interact with Myocd and SRF to promote cardiomyocyte proliferation by regulating CDK and cyclin genes.
Volume: 150
Issue: 24
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Protein
Q8VIM5
Organism: Mus musculus/domesticus
Length: 935  
Fragment?: false
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Publication
17940050 | J:149882
First Author: Long X
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Myocardin is a bifunctional switch for smooth versus skeletal muscle differentiation.
Volume: 104
Issue: 42
Pages: 16570-5
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Publication
31513549 | J:283803
First Author: Houweling AC
Year: 2019
Journal: J Clin Invest
Title: Loss-of-function variants in myocardin cause congenital megabladder in humans and mice.
Volume: 129
Issue: 12
Pages: 5374-5380
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Publication
33995678 | J:314123
First Author: Zhou Q
Year: 2021
Journal: Theranostics
Title: Targeting hyperactive TGFBR2 for treating MYOCD deficient lung cancer.
Volume: 11
Issue: 13
Pages: 6592-6606
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Publication
34523259 | J:313814
First Author: Thomas S
Year: 2021
Journal: Physiol Rep
Title: miR-145 transgenic mice develop cardiopulmonary complications leading to postnatal death.
Volume: 9
Issue: 17
Pages: e15013
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Publication
25957400 | J:245001
First Author: Baeten JT
Year: 2015
Journal: J Biol Chem
Title: Differential Regulation of NOTCH2 and NOTCH3 Contribute to Their Unique Functions in Vascular Smooth Muscle Cells.
Volume: 290
Issue: 26
Pages: 16226-37
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Publication
25805819 | J:220828
First Author: Huang J
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Myocardin is required for maintenance of vascular and visceral smooth muscle homeostasis during postnatal development.
Volume: 112
Issue: 14
Pages: 4447-52
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Publication
29976770 | J:285162
First Author: Lyu Q
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: CRISPR-Cas9-Mediated Epitope Tagging Provides Accurate and Versatile Assessment of Myocardin-Brief Report.
Volume: 38
Issue: 9
Pages: 2184-2190
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Publication
26453897 | J:227639
First Author: Baeten JT
Year: 2015
Journal: Genesis
Title: Loss of Notch2 and Notch3 in vascular smooth muscle causes patent ductus arteriosus.
Volume: 53
Issue: 12
Pages: 738-48
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Publication
36610028 | J:344822
First Author: Morita T
Year: 2023
Journal: FEBS Open Bio
Title: Actin-related protein 5 suppresses the cooperative activation of cardiac gene transcription by myocardin and MEF2.
Volume: 13
Issue: 2
Pages: 363-379
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Publication
20385216 | J:162813
First Author: Imamura M
Year: 2010
Journal: Gene
Title: Expression and functional activity of four myocardin isoforms.
Volume: 464
Issue: 1-2
Pages: 1-10
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Publication
18188448 | J:131288
First Author: Huang J
Year: 2008
Journal: J Clin Invest
Title: Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice.
Volume: 118
Issue: 2
Pages: 515-25
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Publication
19850880 | J:154666
First Author: Huang J
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Myocardin is required for cardiomyocyte survival and maintenance of heart function.
Volume: 106
Issue: 44
Pages: 18734-9
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Publication
33035679 | J:301536
First Author: Xia XD
Year: 2021
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Myocardin suppression increases lipid retention and atherosclerosis via downregulation of ABCA1 in vascular smooth muscle cells.
Volume: 1866
Issue: 4
Pages: 158824
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Publication
23308271 | J:195713
First Author: DeSouza KR
Year: 2013
Journal: PLoS One
Title: Analysis of the Sonic Hedgehog signaling pathway in normal and abnormal bladder development.
Volume: 8
Issue: 1
Pages: e53675
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Publication
19620969 | J:158135
First Author: Kwon C
Year: 2009
Journal: Nat Cell Biol
Title: A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate.
Volume: 11
Issue: 8
Pages: 951-7
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Publication
17215356 | J:119251
First Author: Chow N
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype.
Volume: 104
Issue: 3
Pages: 823-8
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Publication
19797053 | J:177245
First Author: Sun Q
Year: 2009
Journal: J Biol Chem
Title: Myocardin-dependent activation of the CArG box-rich smooth muscle gamma-actin gene: preferential utilization of a single CArG element through functional association with the NKX3.1 homeodomain protein.
Volume: 284
Issue: 47
Pages: 32582-90
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Publication
16224064 | J:117514
First Author: Qiu P
Year: 2005
Journal: Circ Res
Title: Myocardin enhances Smad3-mediated transforming growth factor-beta1 signaling in a CArG box-independent manner: Smad-binding element is an important cis element for SM22alpha transcription in vivo.
Volume: 97
Issue: 10
Pages: 983-91
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Publication
23671695 | J:202129
First Author: Martin E
Year: 2013
Journal: PLoS One
Title: TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in the ureter by reducing myocardin activity.
Volume: 8
Issue: 5
Pages: e63721
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Publication
22996691 | J:192465
First Author: Huang J
Year: 2012
Journal: J Clin Invest
Title: Myocardin regulates BMP10 expression and is required for heart development.
Volume: 122
Issue: 10
Pages: 3678-91
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Publication
35103284 | J:321979
 
First Author: Kurz J
Year: 2022
Journal: Development
Title: Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter.
Volume: 149
Issue: 4
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Publication
29093270 | J:282119
 
First Author: Koenig SN
Year: 2017
Journal: JCI Insight
Title: Notch1 haploinsufficiency causes ascending aortic aneurysms in mice.
Volume: 2
Issue: 21
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Protein Coding Gene
MGP_CAROLIEiJ_G0016512 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018476 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018445 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018414 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018416 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018229 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2137495 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018868 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017785 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018203 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018312 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018302 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018384 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018326 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018909 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017559 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017838 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017641 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017349 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
21357509 | J:169676
First Author: Hoofnagle MH
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Myocardin is differentially required for the development of smooth muscle cells and cardiomyocytes.
Volume: 300
Issue: 5
Pages: H1707-21
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Publication
24252873 | J:207845
 
First Author: Heidersbach A
Year: 2013
Journal: Elife
Title: microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart.
Volume: 2
Pages: e01323
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Publication
25573853 | J:241201
First Author: Vengrenyuk Y
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: Cholesterol loading reprograms the microRNA-143/145-myocardin axis to convert aortic smooth muscle cells to a dysfunctional macrophage-like phenotype.
Volume: 35
Issue: 3
Pages: 535-46
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Publication
28342807 | J:287037
 
First Author: Li H
Year: 2017
Journal: Gene
Title: Myocardin inhibited the gap protein connexin 43 via promoted miR-206 to regulate vascular smooth muscle cell phenotypic switch.
Volume: 616
Pages: 22-30
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Publication
17360478 | J:248206
First Author: Li HJ
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Steroid receptor coactivator 3 is a coactivator for myocardin, the regulator of smooth muscle transcription and differentiation.
Volume: 104
Issue: 10
Pages: 4065-70
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Publication
17021041 | J:115138
First Author: Creemers EE
Year: 2006
Journal: Development
Title: Myocardin is a direct transcriptional target of Mef2, Tead and Foxo proteins during cardiovascular development.
Volume: 133
Issue: 21
Pages: 4245-56
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Publication
17292825 | J:118335
First Author: Milyavsky M
Year: 2007
Journal: Cancer Cell
Title: Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect.
Volume: 11
Issue: 2
Pages: 133-46
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Publication
31029421 | J:291204
First Author: Luo Y
Year: 2019
Journal: Biochem Biophys Res Commun
Title: MiR-466h-5p induces expression of myocardin with complementary promoter sequences.
Volume: 514
Issue: 1
Pages: 187-193
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Publication
25614278 | J:318279
First Author: Ackers-Johnson M
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: Myocardin regulates vascular smooth muscle cell inflammatory activation and disease.
Volume: 35
Issue: 4
Pages: 817-28
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GXD Expression
GXD Expression
     
Probe: MGI:3054910
Assay Type: RT-PCR
Annotation Date: 2004-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:3054928
Age: embryonic day 9.5
Specimen Label: + S/S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3054910
Assay Type: RT-PCR
Annotation Date: 2004-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:3054928
Age: embryonic day 9.5
Specimen Label: - S/S
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3054910
Assay Type: RT-PCR
Annotation Date: 2004-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185715
Stage: TS15
Assay Id: MGI:3054928
Age: embryonic day 9.5
Specimen Label: + S/S
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3054910
Assay Type: RT-PCR
Annotation Date: 2004-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185815
Stage: TS15
Assay Id: MGI:3054928
Age: embryonic day 9.5
Specimen Label: + S/S
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3054910
Assay Type: RT-PCR
Annotation Date: 2004-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185715
Stage: TS15
Assay Id: MGI:3054928
Age: embryonic day 9.5
Specimen Label: - S/S
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3054910
Assay Type: RT-PCR
Annotation Date: 2004-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185815
Stage: TS15
Assay Id: MGI:3054928
Age: embryonic day 9.5
Specimen Label: - S/S
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:1860126
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: aorta
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:1860126
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: aorta
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:1860126
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: aorta
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:1832126
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: bladder
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:1832126
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: bladder
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:1832126
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: bladder
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:1702126
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: stomach
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:1702126
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: stomach
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:1702126
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: stomach
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:3287426
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: intestine
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:3287426
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: intestine
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:3287426
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: intestine
Detected: true
Specimen Num: 12
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•
GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: heart
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: heart
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Present
Sex: Female
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: heart
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
       
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Not Specified
Sex: Female
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: brain
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
       
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Not Specified
Sex: Female
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: brain
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
       
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Not Specified
Sex: Female
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: brain
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
       
Probe: MGI:3805888
Assay Type: RT-PCR
Annotation Date: 2008-09-15
Strength: Not Specified
Sex: Female
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:3805923
Age: embryonic day 18.5
Specimen Label: liver
Specimen Num: 19
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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