| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Levi-Montalcini R |
| Year: |
1995 |
| Journal: |
J Neurol Sci |
| Title: |
Update of the NGF saga. |
| Volume: |
130 |
| Issue: |
2 |
| Pages: |
119-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Leborgne NGF |
| Year: |
2020 |
| Journal: |
Front Immunol |
| Title: |
Serpinb1a Is Dispensable for the Development and Cytokine Response of Invariant Natural Killer T Cell Subsets. |
| Volume: |
11 |
|
| Pages: |
562587 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Glebova NO |
| Year: |
2004 |
| Journal: |
J Neurosci |
| Title: |
Heterogeneous requirement of NGF for sympathetic target innervation in vivo. |
| Volume: |
24 |
| Issue: |
3 |
| Pages: |
743-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Davies AM |
| Year: |
1995 |
| Journal: |
Dev Biol |
| Title: |
NGF receptor expression in sensory neurons develops normally in embryos lacking NGF. |
| Volume: |
171 |
| Issue: |
2 |
| Pages: |
434-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Testa G |
| Year: |
2019 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Cholinergic striatal neurons are increased in HSAN V homozygous mice despite reduced NGF bioavailability. |
| Volume: |
509 |
| Issue: |
3 |
| Pages: |
763-766 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Davis BM |
| Year: |
1996 |
| Journal: |
Brain Res |
| Title: |
Effects of NGF overexpression on anatomical and physiological properties of sympathetic postganglionic neurons. |
| Volume: |
724 |
| Issue: |
1 |
| Pages: |
47-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Harrison SM |
| Year: |
2004 |
| Journal: |
Brain Res Mol Brain Res |
| Title: |
Rescue of NGF-deficient mice I: transgenic expression of NGF in skin rescues mice lacking endogenous NGF. |
| Volume: |
122 |
| Issue: |
2 |
| Pages: |
116-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
White FA |
| Year: |
1996 |
| Journal: |
J Neurosci |
| Title: |
Synchronous onset of NGF and TrkA survival dependence in developing dorsal root ganglia. |
| Volume: |
16 |
| Issue: |
15 |
| Pages: |
4662-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Phillips HS |
| Year: |
2004 |
| Journal: |
Brain Res Mol Brain Res |
| Title: |
Rescue of NGF-deficient mice II: basal forebrain cholinergic projections require NGF for target innervation but not guidance. |
| Volume: |
124 |
| Issue: |
1 |
| Pages: |
1-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Harper S |
| Year: |
1990 |
| Journal: |
Development |
| Title: |
NGF mRNA expression in developing cutaneous epithelium related to innervation density. |
| Volume: |
110 |
| Issue: |
2 |
| Pages: |
515-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Luo W |
| Year: |
2007 |
| Journal: |
Neuron |
| Title: |
A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons. |
| Volume: |
54 |
| Issue: |
5 |
| Pages: |
739-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Girard BM |
| Year: |
2011 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
Neurotrophin/receptor expression in urinary bladder of mice with overexpression of NGF in urothelium. |
| Volume: |
300 |
| Issue: |
2 |
| Pages: |
F345-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu RY |
| Year: |
2002 |
| Journal: |
Mol Cell Neurosci |
| Title: |
NGF enhances sensory axon growth induced by laminin but not by the L1 cell adhesion molecule. |
| Volume: |
20 |
| Issue: |
1 |
| Pages: |
2-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Delivanoglou N |
| Year: |
2020 |
| Journal: |
J Neuroinflammation |
| Title: |
Spatio-temporal expression profile of NGF and the two-receptor system, TrkA and p75NTR, in experimental autoimmune encephalomyelitis. |
| Volume: |
17 |
| Issue: |
1 |
| Pages: |
41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Triaca V |
| Year: |
2016 |
| Journal: |
Aging Cell |
| Title: |
NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease. |
| Volume: |
15 |
| Issue: |
4 |
| Pages: |
661-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kioussi C |
| Year: |
1994 |
| Journal: |
J Cell Biol |
| Title: |
Differential induction of Pax genes by NGF and BDNF in cerebellar primary cultures. |
| Volume: |
125 |
| Issue: |
2 |
| Pages: |
417-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lombardi L |
| Year: |
2008 |
| Journal: |
Neurobiol Dis |
| Title: |
Components of the NGF signaling complex are altered in mdx mouse superior cervical ganglion and its target organs. |
| Volume: |
32 |
| Issue: |
3 |
| Pages: |
402-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hassankhani A |
| Year: |
1995 |
| Journal: |
Dev Biol |
| Title: |
Overexpression of NGF within the heart of transgenic mice causes hyperinnervation, cardiac enlargement, and hyperplasia of ectopic cells. |
| Volume: |
169 |
| Issue: |
1 |
| Pages: |
309-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang L |
| Year: |
1994 |
| Journal: |
J Neurosci |
| Title: |
NGF and NT-3 have differing effects on the growth of dorsal root axons in developing mammalian spinal cord. |
| Volume: |
14 |
| Issue: |
9 |
| Pages: |
5187-201 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chou HC |
| Year: |
2001 |
| Journal: |
Anat Embryol (Berl) |
| Title: |
The distribution of PGP9. 5, BDNF and NGF in the vallate papilla of adult and developing mice. |
| Volume: |
204 |
| Issue: |
2 |
| Pages: |
161-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schnegelsberg B |
| Year: |
2010 |
| Journal: |
Am J Physiol Regul Integr Comp Physiol |
| Title: |
Overexpression of NGF in mouse urothelium leads to neuronal hyperinnervation, pelvic sensitivity, and changes in urinary bladder function. |
| Volume: |
298 |
| Issue: |
3 |
| Pages: |
R534-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang W |
| Year: |
2018 |
| Journal: |
Front Aging Neurosci |
| Title: |
Targeted Mutation (R100W) of the Gene Encoding NGF Leads to Deficits in the Peripheral Sensory Nervous System. |
| Volume: |
10 |
|
| Pages: |
373 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Girard BM |
| Year: |
2012 |
| Journal: |
J Mol Neurosci |
| Title: |
Effects of CYP-induced cystitis on PACAP/VIP and receptor expression in micturition pathways and bladder function in mice with overexpression of NGF in urothelium. |
| Volume: |
48 |
| Issue: |
3 |
| Pages: |
730-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Crowley C |
| Year: |
1994 |
| Journal: |
Cell |
| Title: |
Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. |
| Volume: |
76 |
| Issue: |
6 |
| Pages: |
1001-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Forgie A |
| Year: |
2000 |
| Journal: |
Eur J Neurosci |
| Title: |
In vivo survival requirement of a subset of nodose ganglion neurons for nerve growth factor. |
| Volume: |
12 |
| Issue: |
2 |
| Pages: |
670-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen KS |
| Year: |
1997 |
| Journal: |
J Neurosci |
| Title: |
Disruption of a single allele of the nerve growth factor gene results in atrophy of basal forebrain cholinergic neurons and memory deficits. |
| Volume: |
17 |
| Issue: |
19 |
| Pages: |
7288-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dissen GA |
| Year: |
2001 |
| Journal: |
Endocrinology |
| Title: |
Nerve growth factor is required for early follicular development in the mammalian ovary. |
| Volume: |
142 |
| Issue: |
5 |
| Pages: |
2078-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lazaridis I |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. |
| Volume: |
9 |
| Issue: |
4 |
| Pages: |
e1001051 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wilson JL |
| Year: |
2014 |
| Journal: |
Endocrinology |
| Title: |
Excess of nerve growth factor in the ovary causes a polycystic ovary-like syndrome in mice, which closely resembles both reproductive and metabolic aspects of the human syndrome. |
| Volume: |
155 |
| Issue: |
11 |
| Pages: |
4494-506 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
307
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Holmberg K |
| Year: |
2001 |
| Journal: |
Exp Neurol |
| Title: |
Effect of peripheral nerve lesion and lumbar sympathectomy on peptide regulation in dorsal root ganglia in the NGF-overexpressing mouse. |
| Volume: |
167 |
| Issue: |
2 |
| Pages: |
290-303 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Einarsdottir E |
| Year: |
2004 |
| Journal: |
Hum Mol Genet |
| Title: |
A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception. |
| Volume: |
13 |
| Issue: |
8 |
| Pages: |
799-805 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Figueiredo HF |
| Year: |
2001 |
| Journal: |
Mech Dev |
| Title: |
Skin-derived nerve growth factor blocks programmed cell death in the trigeminal ganglia but does not enhance neuron proliferation. |
| Volume: |
109 |
| Issue: |
2 |
| Pages: |
205-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Davis BM |
| Year: |
1994 |
| Journal: |
J Comp Neurol |
| Title: |
Overexpression of nerve growth factor in transgenic mice induces novel sympathetic projections to primary sensory neurons. |
| Volume: |
349 |
| Issue: |
3 |
| Pages: |
464-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Patel TD |
| Year: |
2000 |
| Journal: |
Neuron |
| Title: |
Development of sensory neurons in the absence of NGF/TrkA signaling in vivo. |
| Volume: |
25 |
| Issue: |
2 |
| Pages: |
345-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Manti M |
| Year: |
2020 |
| Journal: |
FASEB J |
| Title: |
Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice. |
| Volume: |
34 |
| Issue: |
11 |
| Pages: |
14440-14457 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brennan C |
| Year: |
1999 |
| Journal: |
Nat Neurosci |
| Title: |
The p75 neurotrophin receptor influences NT-3 responsiveness of sympathetic neurons in vivo. |
| Volume: |
2 |
| Issue: |
8 |
| Pages: |
699-705 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Testa G |
| Year: |
2019 |
| Journal: |
J Neurosci |
| Title: |
The NGFR100W Mutation Specifically Impairs Nociception without Affecting Cognitive Performance in a Mouse Model of Hereditary Sensory and Autonomic Neuropathy Type V. |
| Volume: |
39 |
| Issue: |
49 |
| Pages: |
9702-9715 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hofer M |
| Year: |
1990 |
| Journal: |
EMBO J |
| Title: |
Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. |
| Volume: |
9 |
| Issue: |
8 |
| Pages: |
2459-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Middleton G |
| Year: |
2001 |
| Journal: |
Development |
| Title: |
Populations of NGF-dependent neurones differ in their requirement for BAX to undergo apoptosis in the absence of NGF/TrkA signalling in vivo. |
| Volume: |
128 |
| Issue: |
23 |
| Pages: |
4715-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Frade JM |
| Year: |
1999 |
| Journal: |
Development |
| Title: |
Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord. |
| Volume: |
126 |
| Issue: |
4 |
| Pages: |
683-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamashita N |
| Year: |
2017 |
| Journal: |
Dev Cell |
| Title: |
Phospho-Regulation of Soma-to-Axon Transcytosis of Neurotrophin Receptors. |
| Volume: |
42 |
| Issue: |
6 |
| Pages: |
626-639.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Francis N |
| Year: |
1999 |
| Journal: |
Dev Biol |
| Title: |
NT-3, like NGF, is required for survival of sympathetic neurons, but not their precursors. |
| Volume: |
210 |
| Issue: |
2 |
| Pages: |
411-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo T |
| Year: |
2011 |
| Journal: |
Nat Neurosci |
| Title: |
An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates. |
| Volume: |
14 |
| Issue: |
1 |
| Pages: |
31-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sharma N |
| Year: |
2010 |
| Journal: |
Neuron |
| Title: |
Long-distance control of synapse assembly by target-derived NGF. |
| Volume: |
67 |
| Issue: |
3 |
| Pages: |
422-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ieda M |
| Year: |
2006 |
| Journal: |
Circulation |
| Title: |
Nerve growth factor is critical for cardiac sensory innervation and rescues neuropathy in diabetic hearts. |
| Volume: |
114 |
| Issue: |
22 |
| Pages: |
2351-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Botchkareva NV |
| Year: |
2000 |
| Journal: |
J Invest Dermatol |
| Title: |
Distinct roles for nerve growth factor and brain-derived neurotrophic factor in controlling the rate of hair follicle morphogenesis. |
| Volume: |
114 |
| Issue: |
2 |
| Pages: |
314-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Petrie CN |
| Year: |
2015 |
| Journal: |
Exp Neurol |
| Title: |
Myenteric expression of nerve growth factor and the p75 neurotrophin receptor regulate axonal remodeling as a consequence of colonic inflammation in mice. |
| Volume: |
271 |
|
| Pages: |
228-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yu T |
| Year: |
2014 |
| Journal: |
J Neurosci |
| Title: |
In vivo regulation of NGF-mediated functions by Nedd4-2 ubiquitination of TrkA. |
| Volume: |
34 |
| Issue: |
17 |
| Pages: |
6098-106 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Deppmann CD |
| Year: |
2008 |
| Journal: |
Science |
| Title: |
A model for neuronal competition during development. |
| Volume: |
320 |
| Issue: |
5874 |
| Pages: |
369-73 |
|
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•
•
•
•
|
| Publication |
| First Author: |
Matsui K |
| Year: |
1994 |
| Journal: |
Neurosci Lett |
| Title: |
Developmental changes of nerve growth factor levels in the gracile axonal dystrophy mouse. |
| Volume: |
177 |
| Issue: |
1-2 |
| Pages: |
116-8 |
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•
•
•
•
|
| Publication |
| First Author: |
Harrison SM |
| Year: |
2000 |
| Journal: |
J Comp Neurol |
| Title: |
Levels of nerve growth factor and neurotrophin-3 are affected differentially by the presence of p75 in sympathetic neurons in vivo. |
| Volume: |
424 |
| Issue: |
1 |
| Pages: |
99-110 |
|
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•
•
•
•
|
| Publication |
| First Author: |
Kerr B |
| Year: |
2009 |
| Journal: |
Reproduction |
| Title: |
NTRK1 and NTRK2 receptors facilitate follicle assembly and early follicular development in the mouse ovary. |
| Volume: |
138 |
| Issue: |
1 |
| Pages: |
131-40 |
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•
•
•
•
|
| Publication |
| First Author: |
Wheeler MA |
| Year: |
2014 |
| Journal: |
Neuron |
| Title: |
TNF-α/TNFR1 signaling is required for the development and function of primary nociceptors. |
| Volume: |
82 |
| Issue: |
3 |
| Pages: |
587-602 |
|
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•
•
•
•
|
| Publication |
| First Author: |
Wickramasinghe SR |
| Year: |
2008 |
| Journal: |
Neuron |
| Title: |
Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. |
| Volume: |
58 |
| Issue: |
4 |
| Pages: |
532-45 |
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•
•
•
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| Author |
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•
•
•
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| Publication |
| First Author: |
Andres R |
| Year: |
2008 |
| Journal: |
Neurosci Lett |
| Title: |
Regulation of sympathetic neuron differentiation by endogenous nerve growth factor and neurotrophin-3. |
| Volume: |
431 |
| Issue: |
3 |
| Pages: |
241-6 |
|
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•
•
•
•
|
| Publication |
| First Author: |
Sedý J |
| Year: |
2004 |
| Journal: |
Dev Dyn |
| Title: |
Pacinian corpuscle development involves multiple Trk signaling pathways. |
| Volume: |
231 |
| Issue: |
3 |
| Pages: |
551-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kolbeck R |
| Year: |
1999 |
| Journal: |
J Neurochem |
| Title: |
Brain-derived neurotrophic factor levels in the nervous system of wild-type and neurotrophin gene mutant mice. |
| Volume: |
72 |
| Issue: |
5 |
| Pages: |
1930-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang S |
| Year: |
2015 |
| Journal: |
Elife |
| Title: |
Extrinsic and intrinsic signals converge on the Runx1/CBFβ transcription factor for nonpeptidergic nociceptor maturation. |
| Volume: |
4 |
|
| Pages: |
e10874 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Siao CJ |
| Year: |
2012 |
| Journal: |
J Exp Med |
| Title: |
ProNGF, a cytokine induced after myocardial infarction in humans, targets pericytes to promote microvascular damage and activation. |
| Volume: |
209 |
| Issue: |
12 |
| Pages: |
2291-305 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fundin BT |
| Year: |
1997 |
| Journal: |
Dev Biol |
| Title: |
Differential dependency of cutaneous mechanoreceptors on neurotrophins, trk receptors, and P75 LNGFR. |
| Volume: |
190 |
| Issue: |
1 |
| Pages: |
94-116 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Selby MJ |
| Year: |
1987 |
| Journal: |
Mol Cell Biol |
| Title: |
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2023 |
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Nat Cell Biol |
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Leptin receptor(+) cells promote bone marrow innervation and regeneration by synthesizing nerve growth factor. |
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2016 |
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Mol Cell Endocrinol |
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436 |
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J Immunol |
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DNA Cell Biol |
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Method for quantitation of low-abundance nerve growth factor mRNA expression in human nervous tissue using competitive reverse transcription polymerase chain reaction. |
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2015 |
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Stem Cells |
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Nerve growth factor and proNGF simultaneously promote symmetric self-renewal, quiescence, and epithelial to mesenchymal transition to enlarge the breast cancer stem cell compartment. |
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33 |
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2 |
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Nerve growth factor promotes cardiac repair following myocardial infarction. |
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Biochim Biophys Acta |
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Hepatic nerve growth factor induced by iron overload triggers defenestration in liver sinusoidal endothelial cells. |
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Sci Adv |
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NGF-p75 signaling coordinates skeletal cell migration during bone repair. |
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Cell Rep |
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NGF-TrkA Signaling by Sensory Nerves Coordinates the Vascularization and Ossification of Developing Endochondral Bone. |
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