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Search results 1 to 100 out of 2317 for Nkx2-1

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Type Details Score
Publication
28266561 | J:275078
 
First Author: Minocha S
Year: 2017
Journal: Sci Rep
Title: Nkx2.1 regulates the generation of telencephalic astrocytes during embryonic development.
Volume: 7
Pages: 43093
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Publication
23562608 | J:198191
First Author: Li C
Year: 2013
Journal: Dev Biol
Title: Apc deficiency alters pulmonary epithelial cell fate and inhibits Nkx2.1 via triggering TGF-beta signaling.
Volume: 378
Issue: 1
Pages: 13-24
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Publication
18602626 | J:138200
First Author: Xing Y
Year: 2008
Journal: Dev Biol
Title: Mechanisms of TGFbeta inhibition of LUNG endodermal morphogenesis: the role of TbetaRII, Smads, Nkx2.1 and Pten.
Volume: 320
Issue: 2
Pages: 340-50
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Publication
19711380 | J:161578
First Author: Yee CL
Year: 2009
Journal: J Comp Neurol
Title: Arcuate nucleus expression of NKX2.1 and DLX and lineages expressing these transcription factors in neuropeptide Y(+), proopiomelanocortin(+), and tyrosine hydroxylase(+) neurons in neonatal and adult mice.
Volume: 517
Issue: 1
Pages: 37-50
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Publication
24157949 | J:205340
First Author: Zhao Y
Year: 2014
Journal: Dev Biol
Title: Ldb1 is essential for development of Nkx2.1 lineage derived GABAergic and cholinergic neurons in the telencephalon.
Volume: 385
Issue: 1
Pages: 94-106
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Publication
32375878 | J:317669
First Author: Haji N
Year: 2020
Journal: Mol Autism
Title: Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice.
Volume: 11
Issue: 1
Pages: 29
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Publication
28546511 | J:243650
First Author: Herriges MJ
Year: 2017
Journal: Genes Dev
Title: The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis.
Volume: 31
Issue: 9
Pages: 889-903
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Publication
18339674 | J:135983
First Author: Du T
Year: 2008
Journal: Development
Title: NKX2.1 specifies cortical interneuron fate by activating Lhx6.
Volume: 135
Issue: 8
Pages: 1559-67
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Publication
17220277 | J:118897
First Author: Minoo P
Year: 2007
Journal: Mol Cell Biol
Title: Physical and functional interactions between homeodomain NKX2.1 and winged helix/forkhead FOXA1 in lung epithelial cells.
Volume: 27
Issue: 6
Pages: 2155-65
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Publication
12930780 | J:85473
First Author: Corbin JG
Year: 2003
Journal: Development
Title: Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning.
Volume: 130
Issue: 20
Pages: 4895-906
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Publication
19581346 | J:152193
First Author: Hoshi S
Year: 2009
Journal: Carcinogenesis
Title: Role of NKX2-1 in N-bis(2-hydroxypropyl)-nitrosamine-induced thyroid adenoma in mice.
Volume: 30
Issue: 9
Pages: 1614-9
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Publication
18786356 | J:145461
First Author: Butt SJ
Year: 2008
Journal: Neuron
Title: The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes.
Volume: 59
Issue: 5
Pages: 722-32
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Publication
10393115 | J:55842
First Author: Sussel L
Year: 1999
Journal: Development
Title: Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum.
Volume: 126
Issue: 15
Pages: 3359-70
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Publication
23143308 | J:193977
First Author: Maeda Y
Year: 2012
Journal: J Clin Invest
Title: Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung.
Volume: 122
Issue: 12
Pages: 4388-400
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Publication
12902388 | J:102348
First Author: Nery S
Year: 2003
Journal: Cereb Cortex
Title: Dlx2 progenitor migration in wild type and Nkx2.1 mutant telencephalon.
Volume: 13
Issue: 9
Pages: 895-903
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Publication
20181579 | J:157830
First Author: Flandin P
Year: 2010
Journal: J Neurosci
Title: The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons.
Volume: 30
Issue: 8
Pages: 2812-23
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Publication
16510470 | J:121211
First Author: Yin Z
Year: 2006
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulmonary gene expression.
Volume: 291
Issue: 2
Pages: L191-9
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Publication
33428297 | J:308018
First Author: Li E
Year: 2021
Journal: Dev Dyn
Title: Blastocyst complementation reveals that NKX2-1 establishes the proximal-peripheral boundary of the airway epithelium.
Volume: 250
Issue: 7
Pages: 1001-1020
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Publication
31813798 | J:292005
First Author: Kim E
Year: 2019
Journal: Dev Cell
Title: Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation.
Volume: 51
Issue: 6
Pages: 675-683.e4
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Publication
23444355 | J:194843
First Author: Ferri A
Year: 2013
Journal: Development
Title: Sox2 is required for embryonic development of the ventral telencephalon through the activation of the ventral determinants Nkx2.1 and Shh.
Volume: 140
Issue: 6
Pages: 1250-61
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Publication
30332632 | J:278145
First Author: Mollaoglu G
Year: 2018
Journal: Immunity
Title: The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment.
Volume: 49
Issue: 4
Pages: 764-779.e9
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Publication
23523371 | J:198227
First Author: Snyder EL
Year: 2013
Journal: Mol Cell
Title: Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.
Volume: 50
Issue: 2
Pages: 185-99
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Publication
30002193 | J:266844
First Author: Caswell DR
Year: 2018
Journal: Mol Cancer Res
Title: Tumor Suppressor Activity of Selenbp1, a Direct Nkx2-1 Target, in Lung Adenocarcinoma.
Volume: 16
Issue: 11
Pages: 1737-1749
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Publication
18632661 | J:141842
First Author: Tomita T
Year: 2008
Journal: J Biol Chem
Title: CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression.
Volume: 283
Issue: 37
Pages: 25617-27
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Publication
30886014 | J:276237
First Author: Orquera DP
Year: 2019
Journal: J Neurosci
Title: The Homeodomain Transcription Factor NKX2.1 Is Essential for the Early Specification of Melanocortin Neuron Identity and Activates Pomc Expression in the Developing Hypothalamus.
Volume: 39
Issue: 21
Pages: 4023-4035
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Publication
27657450 | J:266826
First Author: Sandberg M
Year: 2016
Journal: Neuron
Title: Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.
Volume: 91
Issue: 6
Pages: 1260-1275
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Publication
18786357 | J:145460
First Author: Nóbrega-Pereira S
Year: 2008
Journal: Neuron
Title: Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors.
Volume: 59
Issue: 5
Pages: 733-45
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Publication
28813670 | J:254523
First Author: Magno L
Year: 2017
Journal: Cell Rep
Title: NKX2-1 Is Required in the Embryonic Septum for Cholinergic System Development, Learning, and Memory.
Volume: 20
Issue: 7
Pages: 1572-1584
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Publication
38114516 | J:344378
First Author: Toth A
Year: 2023
Journal: Nat Commun
Title: Alveolar epithelial progenitor cells require Nkx2-1 to maintain progenitor-specific epigenomic state during lung homeostasis and regeneration.
Volume: 14
Issue: 1
Pages: 8452
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Publication
33947861 | J:307465
First Author: Little DR
Year: 2021
Journal: Nat Commun
Title: Differential chromatin binding of the lung lineage transcription factor NKX2-1 resolves opposing murine alveolar cell fates in vivo.
Volume: 12
Issue: 1
Pages: 2509
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Publication
39284798 | J:354192
First Author: He H
Year: 2024
Journal: Nat Commun
Title: PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function.
Volume: 15
Issue: 1
Pages: 8112
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Publication
11854319 | J:74697
First Author: Krude H
Year: 2002
Journal: J Clin Invest
Title: Choreoathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiency.
Volume: 109
Issue: 4
Pages: 475-80
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Publication
19766601 | J:158870
 
First Author: Magno L
Year: 2009
Journal: Brain Res
Title: Ongoing expression of Nkx2.1 in the postnatal mouse forebrain: potential for understanding NKX2.1 haploinsufficiency in humans?
Volume: 1304
Pages: 164-86
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Gene
100506237 | NKX2-1-AS1
Type: gene
Organism: human
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Publication
32445470 | J:310130
First Author: Jia S
Year: 2020
Journal: Acta Biochim Biophys Sin (Shanghai)
Title: Nkx2.1 downregulation is involved in brain abnormality induced by excess retinoic acid.
Volume: 52
Issue: 6
Pages: 683-690
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Protein Coding Gene
MGI:108067 | Nkx2-1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
31813796 | J:359246
First Author: Nasr T
Year: 2019
Journal: Dev Cell
Title: Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog-Gli Is Required for Tracheoesophageal Separation.
Volume: 51
Issue: 6
Pages: 665-674.e6
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Publication
20507551 | J:161400
 
First Author: Carney RS
Year: 2010
Journal: Neural Dev
Title: Sonic hedgehog expressing and responding cells generate neuronal diversity in the medial amygdala.
Volume: 5
Pages: 14
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Publication
17990269 | J:131144
First Author: Xu Q
Year: 2008
Journal: J Comp Neurol
Title: Fate mapping Nkx2.1-lineage cells in the mouse telencephalon.
Volume: 506
Issue: 1
Pages: 16-29
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Publication
33154347 | J:306874
First Author: McSweeney C
Year: 2020
Journal: Transl Psychiatry
Title: Full function of exon junction complex factor, Rbm8a, is critical for interneuron development.
Volume: 10
Issue: 1
Pages: 379
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Publication
34228108 | J:316062
First Author: Siddiqi F
Year: 2021
Journal: Cereb Cortex
Title: Islet1 Precursors Contribute to Mature Interneuron Subtypes in Mouse Neocortex.
Volume: 31
Issue: 11
Pages: 5206-5224
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Publication
24487022 | J:229354
First Author: Heinrich G
Year: 2014
Journal: Diabetes
Title: Preserved energy balance in mice lacking FoxO1 in neurons of Nkx2.1 lineage reveals functional heterogeneity of FoxO1 signaling within the hypothalamus.
Volume: 63
Issue: 5
Pages: 1572-82
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Publication
37534159 | J:338817
First Author: Schoultz E
Year: 2023
Journal: iScience
Title: Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor.
Volume: 26
Issue: 7
Pages: 107071
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Publication
33600763 | J:306212
First Author: Ma T
Year: 2021
Journal: Neuron
Title: Decoding neuronal composition and ontogeny of individual hypothalamic nuclei.
Volume: 109
Issue: 7
Pages: 1150-1167.e6
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Gene
100874189 | NKX2-2-AS1
Type: gene
Organism: human
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GXD Expression
GXD Expression
 
Probe: MGI:7461076
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548437
Age: embryonic day 14.0
Image: 2A Nkx2.1
Specimen Label: 2A Nkx2.1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:2676171
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1685319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6755212
Age: embryonic day 11.5
Image: 4D Aurkb Ct Nkx2.1
Specimen Label: 4D Aurkb Ct Nkx2.1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:2676171
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1685319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6755212
Age: embryonic day 11.5
Image: 4D Aurkb Shh-Cre Nkx2.1
Note: Expression in remnant ot trachea, indicating separation of trachea from esophagus and lung specification had occurred.
Specimen Label: 4D Aurkb Shh-Cre Nkx2.1
Detected: true
Specimen Num: 2
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Gene
key_980033 | Nkx2-1
Type: gene
Organism: Not Specified
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Publication
30679375 | J:272493
First Author: Favuzzi E
Year: 2019
Journal: Science
Title: Distinct molecular programs regulate synapse specificity in cortical inhibitory circuits.
Volume: 363
Issue: 6425
Pages: 413-417
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Publication
20160132 | J:160018
First Author: Amendola E
Year: 2010
Journal: Endocrinology
Title: A locus on mouse chromosome 2 is involved in susceptibility to congenital hypothyroidism and contains an essential gene expressed in thyroid.
Volume: 151
Issue: 4
Pages: 1948-58
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Publication
12141427 | J:80726
First Author: Biben C
Year: 2002
Journal: Int J Dev Biol
Title: NK-2 class homeobox genes and pharyngeal/oral patterning: Nkx2-3 is required for salivary gland and tooth morphogenesis.
Volume: 46
Issue: 4
Pages: 415-22
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Publication
22955271 | J:217271
First Author: Varma S
Year: 2012
Journal: J Biol Chem
Title: The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation.
Volume: 287
Issue: 44
Pages: 37282-95
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Publication
20578903 | J:175294
First Author: Afink GB
Year: 2010
Journal: Thyroid
Title: Initial characterization of C16orf89, a novel thyroid-specific gene.
Volume: 20
Issue: 7
Pages: 811-21
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Publication
19632216 | J:153550
First Author: Yu W
Year: 2009
Journal: Dev Biol
Title: Patterning of ventral telencephalon requires positive function of Gli transcription factors.
Volume: 334
Issue: 1
Pages: 264-75
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Publication
15459176 | J:94409
First Author: Nasonkin IO
Year: 2004
Journal: Hum Mol Genet
Title: Pituitary hypoplasia and respiratory distress syndrome in Prop1 knockout mice.
Volume: 13
Issue: 22
Pages: 2727-35
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Publication
10101124 | J:52751
First Author: Tuttle R
Year: 1999
Journal: Development
Title: Defects in thalamocortical axon pathfinding correlate with altered cell domains in Mash-1-deficient mice.
Volume: 126
Issue: 9
Pages: 1903-16
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Publication
10934256 | J:227683
First Author: Marin O
Year: 2000
Journal: J Neurosci
Title: Origin and molecular specification of striatal interneurons.
Volume: 20
Issue: 16
Pages: 6063-76
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Publication
26490861 | J:226687
First Author: Morello F
Year: 2015
Journal: J Neurosci
Title: Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development.
Volume: 35
Issue: 42
Pages: 14205-19
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Publication
21048141 | J:166699
First Author: Chen L
Year: 2010
Journal: J Neurosci
Title: The mouse homeobox gene Gbx2 is required for the development of cholinergic interneurons in the striatum.
Volume: 30
Issue: 44
Pages: 14824-34
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Publication
38588430 | J:359486
First Author: Miyoshi G
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: Developmental trajectories of GABAergic cortical interneurons are sequentially modulated by dynamic FoxG1 expression levels.
Volume: 121
Issue: 16
Pages: e2317783121
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Publication
12821380 | J:84337
First Author: Kawano H
Year: 2003
Journal: Exp Neurol
Title: Aberrant trajectory of ascending dopaminergic pathway in mice lacking Nkx2.1.
Volume: 182
Issue: 1
Pages: 103-12
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Publication
15028753 | J:97012
First Author: Xu Q
Year: 2004
Journal: J Neurosci
Title: Origins of cortical interneuron subtypes.
Volume: 24
Issue: 11
Pages: 2612-22
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Publication
11493571 | J:70747
First Author: Tekki-Kessaris N
Year: 2001
Journal: Development
Title: Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon.
Volume: 128
Issue: 13
Pages: 2545-54
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Publication
10706142 | J:60228
First Author: Yuan B
Year: 2000
Journal: Dev Dyn
Title: Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos.
Volume: 217
Issue: 2
Pages: 180-90
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Publication
11171336 | J:67154
First Author: Nery S
Year: 2001
Journal: Development
Title: Sonic hedgehog contributes to oligodendrocyte specification in the mammalian forebrain.
Volume: 128
Issue: 4
Pages: 527-40
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Publication
11830575 | J:74238
First Author: Marín O
Year: 2002
Journal: Development
Title: Patterning of the basal telencephalon and hypothalamus is essential for guidance of cortical projections.
Volume: 129
Issue: 3
Pages: 761-73
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Publication
21345181 | J:169693
 
First Author: Silberschmidt D
Year: 2011
Journal: BMC Dev Biol
Title: In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1.
Volume: 11
Pages: 9
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Publication
17164424 | J:117072
First Author: Zhang Y
Year: 2007
Journal: Development
Title: GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo.
Volume: 134
Issue: 1
Pages: 189-98
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Publication
23420573 | J:241831
First Author: Niquille M
Year: 2013
Journal: Dev Neurobiol
Title: Two specific populations of GABAergic neurons originating from the medial and the caudal ganglionic eminences aid in proper navigation of callosal axons.
Volume: 73
Issue: 9
Pages: 647-72
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Publication
30397221 | J:268729
First Author: Reale C
Year: 2018
Journal: Sci Rep
Title: Genetic background and window of exposure contribute to thyroid dysfunction promoted by low-dose exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice.
Volume: 8
Issue: 1
Pages: 16324
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Publication
10208743 | J:54641
First Author: Minoo P
Year: 1999
Journal: Dev Biol
Title: Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos.
Volume: 209
Issue: 1
Pages: 60-71
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Publication
20697379 | J:167188
First Author: Ozaki T
Year: 2011
Journal: Lab Invest
Title: Development of thyroid gland and ultimobranchial body cyst is independent of p63.
Volume: 91
Issue: 1
Pages: 138-46
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Publication
17522155 | J:122531
First Author: Que J
Year: 2007
Journal: Development
Title: Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm.
Volume: 134
Issue: 13
Pages: 2521-31
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Publication
11163262 | J:66506
First Author: Pleasure SJ
Year: 2000
Journal: Neuron
Title: Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons.
Volume: 28
Issue: 3
Pages: 727-40
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Publication
19913007 | J:157262
First Author: Ioannides AS
Year: 2010
Journal: Dev Biol
Title: Foregut separation and tracheo-oesophageal malformations: the role of tracheal outgrowth, dorso-ventral patterning and programmed cell death.
Volume: 337
Issue: 2
Pages: 351-62
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Publication
20147383 | J:157922
First Author: Xing Y
Year: 2010
Journal: Development
Title: Signaling via Alk5 controls the ontogeny of lung Clara cells.
Volume: 137
Issue: 5
Pages: 825-33
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Publication
15264213 | J:92138
First Author: Kang Y
Year: 2004
Journal: Mol Carcinog
Title: Nkx2.1 transcription factor in lung cells and a transforming growth factor-beta1 heterozygous mouse model of lung carcinogenesis.
Volume: 40
Issue: 4
Pages: 212-31
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Publication
16613831 | J:108506
First Author: Storm EE
Year: 2006
Journal: Development
Title: Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers.
Volume: 133
Issue: 9
Pages: 1831-44
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Publication
26166575 | J:224836
First Author: Hoch RV
Year: 2015
Journal: Cell Rep
Title: OTX2 Transcription Factor Controls Regional Patterning within the Medial Ganglionic Eminence and Regional Identity of the Septum.
Volume: 12
Issue: 3
Pages: 482-94
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Publication
21303850 | J:169134
First Author: Domyan ET
Year: 2011
Journal: Development
Title: Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2.
Volume: 138
Issue: 5
Pages: 971-81
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Publication
32868762 | J:295412
First Author: Kim DW
Year: 2020
Journal: Nat Commun
Title: The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development.
Volume: 11
Issue: 1
Pages: 4360
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Publication
30063881 | J:266266
First Author: Newman EA
Year: 2018
Journal: Dev Biol
Title: Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus.
Volume: 442
Issue: 2
Pages: 236-248
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Publication
29440304 | J:260467
 
First Author: Ostrin EJ
Year: 2018
Journal: Development
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