| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li L |
| Year: |
2023 |
| Journal: |
Cell Rep |
| Title: |
Mitigation of non-alcoholic steatohepatitis via recombinant Orosomucoid 2, an acute phase protein modulating the Erk1/2-PPARγ-Cd36 pathway. |
| Volume: |
42 |
| Issue: |
7 |
| Pages: |
112697 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhou B |
| Year: |
2022 |
| Journal: |
Nat Metab |
| Title: |
Orosomucoid 2 maintains hepatic lipid homeostasis through suppression of de novo lipogenesis. |
| Volume: |
4 |
| Issue: |
9 |
| Pages: |
1185-1201 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee SC |
| Year: |
1989 |
| Journal: |
DNA |
| Title: |
Molecular cloning of cDNAs corresponding to two genes of alpha 1-acid glycoprotein and characterization of two alleles of AGP-1 in the mouse. |
| Volume: |
8 |
| Issue: |
4 |
| Pages: |
245-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Prowse KR |
| Year: |
1990 |
| Journal: |
J Biol Chem |
| Title: |
Molecular characterization and acute phase expression of the multiple Mus caroli alpha 1-acid glycoprotein (AGP) genes. Differences in glucocorticoid stimulation and regulatory elements between the rat and mouse AGP genes. |
| Volume: |
265 |
| Issue: |
18 |
| Pages: |
10201-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alam T |
| Year: |
1992 |
| Journal: |
Biochemistry |
| Title: |
Interaction of acute-phase-inducible and liver-enriched nuclear factors with the promoter region of the mouse alpha 1-acid glycoprotein gene-1. |
| Volume: |
31 |
| Issue: |
7 |
| Pages: |
1928-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Davisson MT |
| Year: |
1986 |
| Journal: |
Mouse News Lett |
| Title: |
[Alpha-1-acid glycoprotein-1 changed to orosomucoid-1 (Orm-1).] |
| Volume: |
75 |
|
| Pages: |
8 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cooper R |
| Year: |
1987 |
| Journal: |
Biochemistry |
| Title: |
Nucleotide sequence of the mouse alpha 1-acid glycoprotein gene 1. |
| Volume: |
26 |
| Issue: |
17 |
| Pages: |
5244-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Watanabe H |
| Year: |
2020 |
| Journal: |
Sci Rep |
| Title: |
A synthetic retinoic acid receptor agonist Am80 ameliorates renal fibrosis via inducing the production of alpha-1-acid glycoprotein. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
11424 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakamura Y |
| Year: |
2024 |
| Journal: |
Mol Pharm |
| Title: |
Contribution of the α(1)-Acid Glycoprotein in Drug Pharmacokinetics: The Usefulness of α(1)-Acid Glycoprotein-Knockout Mice. |
| Volume: |
21 |
| Issue: |
7 |
| Pages: |
3144-3150 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Watanabe H |
| Year: |
2021 |
| Journal: |
Sci Rep |
| Title: |
An acute phase protein α1-acid glycoprotein mitigates AKI and its progression to CKD through its anti-inflammatory action. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
7953 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chang CJ |
| Year: |
1992 |
| Journal: |
DNA Cell Biol |
| Title: |
Structure and expression of mouse alpha 1-acid glycoprotein gene-3 (AGP-3). |
| Volume: |
11 |
| Issue: |
4 |
| Pages: |
315-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cooper R |
| Year: |
1986 |
| Journal: |
J Biol Chem |
| Title: |
Evidence for the existence of multiple alpha 1-acid glycoprotein genes in the mouse. |
| Volume: |
261 |
| Issue: |
4 |
| Pages: |
1849-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Craig AG |
| Year: |
1985 |
| Journal: |
Biochem J |
| Title: |
A mouse gene family associated with a major submaxillary-gland glycoprotein. |
| Volume: |
225 |
| Issue: |
3 |
| Pages: |
657-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee SH |
| Year: |
2021 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
The bile acid induced hepatokine orosomucoid suppresses adipocyte differentiation. |
| Volume: |
534 |
|
| Pages: |
864-870 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Johansson AC |
| Year: |
2002 |
| Journal: |
Eur J Immunol |
| Title: |
The genetic control of sialadenitis versus arthritis in a NOD.QxB10.Q F2 cross. |
| Volume: |
32 |
| Issue: |
1 |
| Pages: |
243-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mburu P |
| Year: |
2003 |
| Journal: |
Nat Genet |
| Title: |
Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31. |
| Volume: |
34 |
| Issue: |
4 |
| Pages: |
421-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baumann H |
| Year: |
1984 |
| Journal: |
Mouse News Lett |
| Title: |
Genetic analysis of the major acute phase reactants in the mouse: chromosomal location of the structural genes for haptoglobin and alpha-1-acid glycoprotein-2 |
| Volume: |
71 |
|
| Pages: |
49 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baumann H |
| Year: |
1984 |
| Journal: |
J Biol Chem |
| Title: |
The acute phase response of mouse liver. Genetic analysis of the major acute phase reactants. |
| Volume: |
259 |
| Issue: |
1 |
| Pages: |
566-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baumann H |
| Year: |
1985 |
| Journal: |
Mol Gen Genet |
| Title: |
Genetics and evolution of the acute phase proteins in mice. |
| Volume: |
201 |
| Issue: |
3 |
| Pages: |
505-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bahary N |
| Year: |
1992 |
| Journal: |
Genomics |
| Title: |
Molecular mapping of mouse chromosomes 4 and 6: use of a flow-sorted Robertsonian chromosome. |
| Volume: |
13 |
| Issue: |
3 |
| Pages: |
761-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Greenfield AJ |
| Year: |
1992 |
| Journal: |
Mouse Genome |
| Title: |
Mappping of clone D4Smh6b to the distal end of mouse chromosome 4 |
| Volume: |
90 |
| Issue: |
1 |
| Pages: |
94-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bahary N |
| Year: |
1991 |
| Journal: |
Genomics |
| Title: |
Molecular genetic linkage maps of mouse chromosomes 4 and 6. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
33-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Committee on Standardized Genetic Nomenclature for Mice |
| Year: |
1993 |
|
| Title: |
Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Velocigene |
| Year: |
2008 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Allele |
| Name: |
orosomucoid 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
ORMDL family members include ORMDL1/2/3 from humans and their homologues, such as protein Orm1 and Orm2 from budding yeasts. ORMDLs may be involved in protein folding in the endoplasmic reticulum []. In budding yeast, Orm1 and Orm2 proteins mediate sphingolipid homeostasis []. |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
153
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
153
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
153
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hjelmqvist L |
| Year: |
2002 |
| Journal: |
Genome Biol |
| Title: |
ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins. |
| Volume: |
3 |
| Issue: |
6 |
| Pages: |
RESEARCH0027 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Breslow DK |
| Year: |
2010 |
| Journal: |
Nature |
| Title: |
Orm family proteins mediate sphingolipid homeostasis. |
| Volume: |
463 |
| Issue: |
7284 |
| Pages: |
1048-53 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Spiller F |
| Year: |
2012 |
| Journal: |
Diabetes |
| Title: |
α1-Acid glycoprotein decreases neutrophil migration and increases susceptibility to sepsis in diabetic mice. |
| Volume: |
61 |
| Issue: |
6 |
| Pages: |
1584-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsusaka K |
| Year: |
2021 |
| Journal: |
Cancer Res |
| Title: |
α1-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages. |
| Volume: |
81 |
| Issue: |
17 |
| Pages: |
4545-4559 |
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