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Search results 1 to 100 out of 509 for Phex

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Hits by Strain

Type Details Score
Gene
5251 | PHEX
Type: gene
Organism: human
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Gene
100496470 | phex
Type: gene
Organism: frog, western clawed
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Gene
119868400 | PHEX
Type: gene
Organism: dog, domestic
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Gene
25512 | Phex
Type: gene
Organism: rat
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Gene
465533 | PHEX
Type: gene
Organism: chimpanzee
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Gene
536029 | PHEX
Type: gene
Organism: cattle
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Gene
395777 | PHEX
Type: gene
Organism: chicken
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Gene
386969 | phex
Type: gene
Organism: zebrafish
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Gene
697025 | PHEX
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:107489 | Phex
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
A2ICR0
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: false
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Publication
17710565 | J:136463
First Author: Xiong X
Year: 2008
Journal: J Biomed Sci
Title: A novel Phex mutation with defective glycosylation causes hypophosphatemia and rickets in mice.
Volume: 15
Issue: 1
Pages: 47-59
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GXD Expression
GXD Expression
     
Probe: MGI:7491754
Assay Type: RT-PCR
Annotation Date: 2023-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768125
Stage: TS25
Assay Id: MGI:7491759
Age: embryonic day 17.5
Specimen Label: Phex
Detected: true
Specimen Num: 1
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Publication
11517178 | J:71057
First Author: Liu S
Year: 2001
Journal: Endocrinology
Title: Cloning and characterization of the proximal murine Phex promoter.
Volume: 142
Issue: 9
Pages: 3987-95
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Gene
100873942 | PHEX-AS1
Type: gene
Organism: human
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Publication
11159866 | J:67356
First Author: Miao D
Year: 2001
Journal: Endocrinology
Title: Osteomalacia in hyp mice is associated with abnormal phex expression and with altered bone matrix protein expression and deposition.
Volume: 142
Issue: 2
Pages: 926-39
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Publication
18597632 | J:153409
First Author: Addison WN
Year: 2008
Journal: J Bone Miner Res
Title: MEPE-ASARM peptides control extracellular matrix mineralization by binding to hydroxyapatite: an inhibition regulated by PHEX cleavage of ASARM.
Volume: 23
Issue: 10
Pages: 1638-49
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Publication
11713245 | J:74324
First Author: Liu S
Year: 2002
Journal: J Biol Chem
Title: Overexpression of Phex in osteoblasts fails to rescue the Hyp mouse phenotype.
Volume: 277
Issue: 5
Pages: 3686-97
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Publication
15029877 | J:88352
First Author: Lorenz-Depiereux B
Year: 2004
Journal: Mamm Genome
Title: New intragenic deletions in the Phex gene clarify X-linked hypophosphatemia-related abnormalities in mice.
Volume: 15
Issue: 3
Pages: 151-61
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Publication
23028440 | J:192046
First Author: Han F
Year: 2012
Journal: PLoS One
Title: Mutation in Phex gene predisposes BALB/c-Phex(Hyp-Duk)/Y mice to otitis media.
Volume: 7
Issue: 9
Pages: e43010
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Publication
9063736 | J:38621
First Author: Strom TM
Year: 1997
Journal: Hum Mol Genet
Title: Pex gene deletions in Gy and Hyp mice provide mouse models for X-linked hypophosphatemia.
Volume: 6
Issue: 2
Pages: 165-71
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Publication
11018258 | J:65004
First Author: Hines ER
Year: 2000
Journal: Biochim Biophys Acta
Title: Molecular cloning of the murine PHEX gene promoter.
Volume: 1493
Issue: 3
Pages: 333-6
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Publication
10087298 | J:54052
First Author: Wang L
Year: 1999
Journal: Mamm Genome
Title: Evidence for Phex haploinsufficiency in murine X-linked hypophosphatemia.
Volume: 10
Issue: 4
Pages: 385-9
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Publication
22573557 | J:196537
First Author: Owen C
Year: 2012
Journal: J Cell Biochem
Title: A novel Phex mutation in a new mouse model of hypophosphatemic rickets.
Volume: 113
Issue: 7
Pages: 2432-41
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Publication
17942069 | J:129885
First Author: Onishi T
Year: 2008
Journal: Arch Oral Biol
Title: Phex mutation causes overexpression of FGF23 in teeth.
Volume: 53
Issue: 2
Pages: 99-104
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Publication
11811562 | J:112483
First Author: Thompson DL
Year: 2002
Journal: J Bone Miner Res
Title: Ontogeny of Phex/PHEX protein expression in mouse embryo and subcellular localization in osteoblasts.
Volume: 17
Issue: 2
Pages: 311-20
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Publication
22006791 | J:196643
First Author: Ichikawa S
Year: 2012
Journal: J Bone Miner Res
Title: A Phex mutation in a murine model of X-linked hypophosphatemia alters phosphate responsiveness of bone cells.
Volume: 27
Issue: 2
Pages: 453-60
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Publication
15940367 | J:111519
First Author: Erben RG
Year: 2005
Journal: J Bone Miner Res
Title: Overexpression of human PHEX under the human beta-actin promoter does not fully rescue the Hyp mouse phenotype.
Volume: 20
Issue: 7
Pages: 1149-60
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Publication
8812412 | J:34935
First Author: Du L
Year: 1996
Journal: Genomics
Title: cDNA cloning of the murine Pex gene implicated in X-linked hypophosphatemia and evidence for expression in bone.
Volume: 36
Issue: 1
Pages: 22-8
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Publication
9077527 | J:39093
First Author: Beck L
Year: 1997
Journal: J Clin Invest
Title: Pex/PEX tissue distribution and evidence for a deletion in the 3' region of the Pex gene in X-linked hypophosphatemic mice.
Volume: 99
Issue: 6
Pages: 1200-9
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Publication
24839967 | J:217349
First Author: Zelenchuk LV
Year: 2014
Journal: PLoS One
Title: PHEX mimetic (SPR4-peptide) corrects and improves HYP and wild type mice energy-metabolism.
Volume: 9
Issue: 5
Pages: e97326
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Publication
12414538 | J:79953
First Author: Carpinelli MR
Year: 2002
Journal: Am J Pathol
Title: An ethyl-nitrosourea-induced point mutation in phex causes exon skipping, x-linked hypophosphatemia, and rickets.
Volume: 161
Issue: 5
Pages: 1925-33
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Publication
18172553 | J:131043
First Author: Yuan B
Year: 2008
Journal: J Clin Invest
Title: Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia.
Volume: 118
Issue: 2
Pages: 722-34
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Publication
15050894 | J:89258
First Author: Miao D
Year: 2004
Journal: Bone
Title: Cartilage abnormalities are associated with abnormal Phex expression and with altered matrix protein and MMP-9 localization in Hyp mice.
Volume: 34
Issue: 4
Pages: 638-47
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Publication
36011266 | J:335128
 
First Author: El Hakam C
Year: 2022
Journal: Genes (Basel)
Title: PHEX(L222P) Mutation Increases Phex Expression in a New ENU Mouse Model for XLH Disease.
Volume: 13
Issue: 8
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Publication
10934642 | J:157605
First Author: Ruchon AF
Year: 2000
Journal: J Bone Miner Res
Title: Developmental expression and tissue distribution of Phex protein: effect of the Hyp mutation and relationship to bone markers.
Volume: 15
Issue: 8
Pages: 1440-50
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Publication
26051469 | J:228153
 
First Author: Zelenchuk LV
Year: 2015
Journal: Bone
Title: Age dependent regulation of bone-mass and renal function by the MEPE ASARM-motif.
Volume: 79
Pages: 131-42
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Publication
22991293 | J:323274
First Author: Barros NM
Year: 2013
Journal: J Bone Miner Res
Title: Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemia.
Volume: 28
Issue: 3
Pages: 688-99
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Publication
9467015 | J:46360
First Author: Lorenz B
Year: 1998
Journal: Hum Mol Genet
Title: Spermine deficiency in Gy mice caused by deletion of the spermine synthase gene.
Volume: 7
Issue: 3
Pages: 541-7
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Publication
15459188 | J:95185
First Author: Wang X
Year: 2004
Journal: J Biol Chem
Title: Spermine synthesis is required for normal viability, growth, and fertility in the mouse.
Volume: 279
Issue: 49
Pages: 51370-5
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Publication
11023830 | J:65535
 
First Author: Mackintosh CA
Year: 2000
Journal: Biochem J
Title: Effect of spermine synthase deficiency on polyamine biosynthesis and content in mice and embryonic fibroblasts, and the sensitivity of fibroblasts to 1,3-bis-(2-chloroethyl)-N-nitrosourea.
Volume: 351 Pt 2
Pages: 439-47
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Publication
- | J:64263
 
First Author: Lyon MF
Year: 1960
Journal: Mouse News Lett
Title: Gy - gyro
Volume: 22
Pages: 30
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Publication
8141332 | J:17268
First Author: Thornton SW
Year: 1994
Journal: Am J Physiol
Title: X-linked hypophosphatemic Gy mice: renal tubular maximum for phosphate vs. brush-border transport after low-P diet.
Volume: 266
Issue: 2 Pt 2
Pages: F309-15
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Publication
8927512 | J:33927
First Author: Beck L
Year: 1996
Journal: Pflugers Arch
Title: Renal expression of Na+-phosphate cotransporter mRNA and protein: effect of the Gy mutation and low phosphate diet.
Volume: 431
Issue: 6
Pages: 936-41
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Publication
1528020 | J:3136
First Author: Scriver CR
Year: 1992
Journal: J Inherit Metab Dis
Title: X-linked hypophosphataemia: a homologous phenotype in humans and mice with unusual organ-specific gene dosage.
Volume: 15
Issue: 4
Pages: 610-24
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Publication
- | J:26058
First Author: Meyer RA
Year: 1994
Journal: Endocrine
Title: Measurement of parathyroid hormone in the mouse: secondary hyperparathyroidism in the X-linked hypophosphatemic (Gyro, gy) mouse.
Volume: 2
Issue: 12
Pages: 1127-1132
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Publication
8717533 | J:36180
First Author: Meyer RA Jr
Year: 1996
Journal: Bone
Title: Effects of altered diet on serum levels of 1,25-dihydroxyvitamin D and parathyroid hormone in X-linked hypophosphatemic (Hyp and Gy) mice.
Volume: 18
Issue: 1
Pages: 23-8
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Publication
1962291 | J:1654
First Author: Shetty NS
Year: 1991
Journal: Teratology
Title: Craniofacial abnormalities in mice with X-linked hypophosphatemic genes (Hyp or Gy).
Volume: 44
Issue: 4
Pages: 463-72
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Publication
1612032 | J:1824
First Author: Tenenhouse HS
Year: 1992
Journal: Endocrinology
Title: Renal phosphate transport and vitamin D metabolism in X-linked hypophosphatemic Gy mice: responses to phosphate deprivation.
Volume: 131
Issue: 1
Pages: 51-6
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Publication
10069185 | J:56014
First Author: Tenenhouse HS
Year: 1999
Journal: Nephrol Dial Transplant
Title: X-linked hypophosphataemia: a homologous disorder in humans and mice.
Volume: 14
Issue: 2
Pages: 333-41
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Publication
8266820 | J:17152
First Author: Woodward JE
Year: 1993
Journal: J Bone Miner Res
Title: Intestinal malabsorption of 45calcium in young Gy mice, a second model for X-linked hypophosphatemia.
Volume: 8
Issue: 11
Pages: 1281-90
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Publication
7853101 | J:24017
First Author: Meyer RA Jr
Year: 1995
Journal: J Orthop Res
Title: Femoral abnormalities and vitamin D metabolism in X-linked hypophosphatemic (Hyp and Gy) mice.
Volume: 13
Issue: 1
Pages: 30-40
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Publication
- | J:13833
 
First Author: Lyon MF
Year: 1980
Journal: Mouse News Lett
Title: Relation of gyro and hypophosphataemia
Volume: 62
Pages: 49
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Publication
3460077 | J:8335
First Author: Lyon MF
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: The Gy mutation: another cause of X-linked hypophosphatemia in mouse.
Volume: 83
Issue: 13
Pages: 4899-903
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Publication
8635692 | J:33265
First Author: Collins JF
Year: 1996
Journal: FASEB J
Title: The molecular defect in the renal sodium-phosphate transporter expression pathway of Gyro (Gy) mice is distinct from that of hypophosphatemic (Hyp) mice.
Volume: 10
Issue: 7
Pages: 751-9
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Publication
9362326 | J:43908
First Author: Econs MJ
Year: 1997
Journal: Am J Physiol
Title: Positional cloning of the PEX gene: new insights into the pathophysiology of X-linked hypophosphatemic rickets.
Volume: 273
Issue: 4 Pt 2
Pages: F489-98
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Publication
9545633 | J:47232
First Author: Meyer RA Jr
Year: 1998
Journal: Genomics
Title: Partial deletion of both the spermine synthase gene and the Pex gene in the X-linked hypophosphatemic, gyro (Gy) mouse.
Volume: 48
Issue: 3
Pages: 289-95
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Publication
8691720 | J:32872
First Author: Tenenhouse HS
Year: 1996
Journal: Kidney Int
Title: Renal Na(+)-phosphate cotransporter gene expression in X-linked Hyp and Gy mice.
Volume: 49
Issue: 4
Pages: 1027-32
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Publication
- | J:28887
First Author: Carter TC
Year: 1960
Journal: Genet Res
Title: The genetic sensitivity to X-rays of mouse foetal gonads.
Volume: 1
Issue: 3
Pages: 351-5
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Publication
18289812 | J:132678
First Author: Megerian CA
Year: 2008
Journal: Hear Res
Title: A mouse model with postnatal endolymphatic hydrops and hearing loss.
Volume: 237
Issue: 1-2
Pages: 90-105
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Publication
30120363 | J:278526
First Author: Pi M
Year: 2018
Journal: Sci Rep
Title: Cardiovascular Interactions between Fibroblast Growth Factor-23 and Angiotensin II.
Volume: 8
Issue: 1
Pages: 12398
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Publication
24601885 | J:210730
First Author: Ma Y
Year: 2014
Journal: Endocrinology
Title: Neither absence nor excess of FGF23 disturbs murine fetal-placental phosphorus homeostasis or prenatal skeletal development and mineralization.
Volume: 155
Issue: 5
Pages: 1596-605
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Publication
27929669 | J:246176
First Author: Ma Y
Year: 2017
Journal: Endocrinology
Title: FGF23 Is Not Required to Regulate Fetal Phosphorus Metabolism but Exerts Effects Within 12 Hours After Birth.
Volume: 158
Issue: 2
Pages: 252-263
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Publication
12900584 | J:85297
First Author: Sabbagh Y
Year: 2002
Journal: Cytogenet Genome Res
Title: The X chromosome deletion in HYP mice extends into the intergenic region but does not include the SAT gene downstream from Phex.
Volume: 99
Issue: 1-4
Pages: 344-9
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Publication
16005844 | J:104579
First Author: Ogawa T
Year: 2006
Journal: Arch Oral Biol
Title: Dentinal defects in Hyp mice not caused by hypophosphatemia alone.
Volume: 51
Issue: 1
Pages: 58-63
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Publication
28764922 | J:257795
 
First Author: Coyac BR
Year: 2017
Journal: Bone
Title: Tissue-specific mineralization defects in the periodontium of the Hyp mouse model of X-linked hypophosphatemia.
Volume: 103
Pages: 334-346
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Publication
19656036 | J:237176
First Author: Fong H
Year: 2009
Journal: J Periodontol
Title: Aberrant cementum phenotype associated with the hypophosphatemic hyp mouse.
Volume: 80
Issue: 8
Pages: 1348-54
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Publication
29878089 | J:264826
First Author: Kaneko I
Year: 2018
Journal: Endocrinology
Title: Eldecalcitol Causes FGF23 Resistance for Pi Reabsorption and Improves Rachitic Bone Phenotypes in the Male Hyp Mouse.
Volume: 159
Issue: 7
Pages: 2741-2758
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Publication
15054142 | J:106264
First Author: Meyer MH
Year: 2004
Journal: Physiol Genomics
Title: The genomic response of the mouse kidney to low-phosphate diet is altered in X-linked hypophosphatemia.
Volume: 18
Issue: 1
Pages: 4-11
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Publication
25460577 | J:217457
 
First Author: Zelenchuk LV
Year: 2015
Journal: Bone
Title: SPR4-peptide alters bone metabolism of normal and HYP mice.
Volume: 72
Pages: 23-33
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Publication
23266491 | J:319019
First Author: Seitz S
Year: 2013
Journal: Bone
Title: Retinol deprivation partially rescues the skeletal mineralization defects of Phex-deficient Hyp mice.
Volume: 53
Issue: 1
Pages: 231-8
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Publication
38050660 | J:357512
First Author: Qian C
Year: 2024
Journal: FEBS Open Bio
Title: A PAI-1 antagonist ameliorates hypophosphatemia in the Hyp vitamin D-resistant rickets model mouse.
Volume: 14
Issue: 2
Pages: 290-299
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Publication
36278488 | J:331927
 
First Author: Buck A
Year: 2022
Journal: JCI Insight
Title: Spatial metabolomics reveals upregulation of several pyrophosphate-producing pathways in cortical bone of Hyp mice.
Volume: 7
Issue: 20
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Publication
14751570 | J:87808
First Author: Qiu ZQ
Year: 2004
Journal: Bone
Title: Effect of gene dose and parental origin on bone histomorphometry in X-linked Hyp mice.
Volume: 34
Issue: 1
Pages: 134-9
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Publication
32116788 | J:351888
 
First Author: Guirado E
Year: 2020
Journal: Front Physiol
Title: Disrupted Protein Expression and Altered Proteolytic Events in Hypophosphatemic Dentin Can Be Rescued by Dentin Matrix Protein 1.
Volume: 11
Pages: 82
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Publication
21854633 | J:237170
 
First Author: Moriyama K
Year: 2011
Journal: J Biomed Sci
Title: Kbus/Idr, a mutant mouse strain with skeletal abnormalities and hypophosphatemia: identification as an allele of 'Hyp'.
Volume: 18
Pages: 60
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Publication
22886699 | J:233262
First Author: Yuan B
Year: 2013
Journal: J Bone Miner Res
Title: Hexa-D-arginine treatment increases 7B2•PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype.
Volume: 28
Issue: 1
Pages: 56-72
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Publication
38331306 | J:347431
 
First Author: Nakanishi T
Year: 2024
Journal: Bone
Title: Complex intrinsic abnormalities in osteoblast lineage cells of X-linked hypophosphatemia: Analysis of human iPS cell models generated by CRISPR/Cas9-mediated gene ablation.
Volume: 181
Pages: 117044
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Publication
28728941 | J:257817
 
First Author: Leifheit-Nestler M
Year: 2017
Journal: Bone
Title: Comparison of calcimimetic R568 and calcitriol in mineral homeostasis in the Hyp mouse, a murine homolog of X-linked hypophosphatemia.
Volume: 103
Pages: 224-232
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Publication
22334725 | J:183792
First Author: Zhang MY
Year: 2012
Journal: Endocrinology
Title: Chronic inhibition of ERK1/2 signaling improves disordered bone and mineral metabolism in hypophosphatemic (Hyp) mice.
Volume: 153
Issue: 4
Pages: 1806-16
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Publication
34523743 | J:323272
First Author: Delsmann MM
Year: 2021
Journal: J Bone Miner Res
Title: Conductive Hearing Loss in the Hyp Mouse Model of X-Linked Hypophosphatemia Is Accompanied by Hypomineralization of the Auditory Ossicles.
Volume: 36
Issue: 12
Pages: 2317-2328
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Publication
34537437 | J:323275
 
First Author: Carpenter KA
Year: 2022
Journal: Bone
Title: Sclerostin antibody improves phosphate metabolism hormones, bone formation rates, and bone mass in adult Hyp mice.
Volume: 154
Pages: 116201
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Publication
15843468 | J:150696
First Author: Liu S
Year: 2005
Journal: J Am Soc Nephrol
Title: Role of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemia.
Volume: 16
Issue: 6
Pages: 1645-53
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Publication
12952859 | J:87132
First Author: Tenenhouse HS
Year: 2003
Journal: Am J Physiol Renal Physiol
Title: Differential effects of Npt2a gene ablation and X-linked Hyp mutation on renal expression of Npt2c.
Volume: 285
Issue: 6
Pages: F1271-8
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Publication
16449303 | J:110579
First Author: Liu S
Year: 2006
Journal: Am J Physiol Endocrinol Metab
Title: Pathogenic role of Fgf23 in Hyp mice.
Volume: 291
Issue: 1
Pages: E38-49
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Publication
19556340 | J:225037
First Author: Liu S
Year: 2009
Journal: Mol Endocrinol
Title: Novel regulators of Fgf23 expression and mineralization in Hyp bone.
Volume: 23
Issue: 9
Pages: 1505-18
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Publication
21312267 | J:233115
First Author: Atkins GJ
Year: 2011
Journal: J Bone Miner Res
Title: Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism.
Volume: 26
Issue: 7
Pages: 1425-36
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Publication
19952276 | J:158461
First Author: Brownstein CA
Year: 2010
Journal: Endocrinology
Title: Increased bone volume and correction of HYP mouse hypophosphatemia in the Klotho/HYP mouse.
Volume: 151
Issue: 2
Pages: 492-501
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Publication
23652555 | J:318824
 
First Author: Uchihashi K
Year: 2013
Journal: Contrib Nephrol
Title: FGF23-induced hypophosphatemia persists in Hyp mice deficient in the WNT coreceptor Lrp6.
Volume: 180
Pages: 124-37
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Publication
23038738 | J:192371
First Author: Karaplis AC
Year: 2012
Journal: Endocrinology
Title: Mineralizing enthesopathy is a common feature of renal phosphate-wasting disorders attributed to FGF23 and is exacerbated by standard therapy in hyp mice.
Volume: 153
Issue: 12
Pages: 5906-17
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Publication
16123154 | J:129835
First Author: Perwad F
Year: 2005
Journal: Endocrinology
Title: Dietary and serum phosphorus regulate fibroblast growth factor 23 expression and 1,25-dihydroxyvitamin D metabolism in mice.
Volume: 146
Issue: 12
Pages: 5358-64
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Title: Overexpression of the DMP1 C-terminal fragment stimulates FGF23 and exacerbates the hypophosphatemic rickets phenotype in Hyp mice.
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