Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Plastin-1 is an actin-bundling protein of the microvilli and stereocilia [, ]. It is the most abundant actin-bundling protein of stereocilia. Mutations in the human PLS1 gene may be associated with relatively mild and progressive forms of hearing loss []. Plastin-1 mediates liquid packing of actin, which is required for stereocilia growth []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Krey JF |
Year: |
2016 |
Journal: |
J Cell Biol |
Title: |
Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid. |
Volume: |
215 |
Issue: |
4 |
Pages: |
467-482 |
|
•
•
•
•
•
|
Publication |
First Author: |
Taylor R |
Year: |
2015 |
Journal: |
Hum Mol Genet |
Title: |
Absence of plastin 1 causes abnormal maintenance of hair cell stereocilia and a moderate form of hearing loss in mice. |
Volume: |
24 |
Issue: |
1 |
Pages: |
37-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Grimm-Günter EM |
Year: |
2009 |
Journal: |
Mol Biol Cell |
Title: |
Plastin 1 binds to keratin and is required for terminal web assembly in the intestinal epithelium. |
Volume: |
20 |
Issue: |
10 |
Pages: |
2549-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Revenu C |
Year: |
2012 |
Journal: |
Mol Biol Cell |
Title: |
A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins. |
Volume: |
23 |
Issue: |
2 |
Pages: |
324-36 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
236
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
138
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
344
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
630
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Western blot |
Annotation Date: |
2015-11-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5695579 |
Age: |
postnatal adult |
Image: |
1 |
|
Specimen Label: |
intestinal epithelium |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Western blot |
Annotation Date: |
2020-08-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6449104 |
Age: |
postnatal adult |
Image: |
1 |
|
Specimen Label: |
2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Western blot |
Annotation Date: |
2020-08-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3592917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:6449104 |
Age: |
embryonic day 10.5 |
Image: |
1 |
|
Specimen Label: |
3 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7855268 |
Assay Type: |
Western blot |
Annotation Date: |
2025-01-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7855420 |
Age: |
embryonic day 18.5 |
Image: |
2 |
|
Specimen Label: |
Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7855268 |
Assay Type: |
Western blot |
Annotation Date: |
2025-01-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7855420 |
Age: |
embryonic day 18.5 |
Image: |
2 |
|
Specimen Label: |
Control |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7855268 |
Assay Type: |
Western blot |
Annotation Date: |
2025-01-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7855420 |
Age: |
embryonic day 18.5 |
Image: |
2 |
|
Specimen Label: |
Control |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7855268 |
Assay Type: |
Western blot |
Annotation Date: |
2025-01-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7855420 |
Age: |
embryonic day 18.5 |
Image: |
2 |
|
Specimen Label: |
Control |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7855268 |
Assay Type: |
Western blot |
Annotation Date: |
2025-01-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7855420 |
Age: |
embryonic day 18.5 |
Image: |
2 |
|
Specimen Label: |
Control |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7855268 |
Assay Type: |
Western blot |
Annotation Date: |
2025-01-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7855420 |
Age: |
embryonic day 18.5 |
Image: |
2 |
|
Specimen Label: |
Control |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7855268 |
Assay Type: |
Western blot |
Annotation Date: |
2025-01-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7855420 |
Age: |
embryonic day 18.5 |
Image: |
2 |
|
Specimen Label: |
Mutant |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7855268 |
Assay Type: |
Western blot |
Annotation Date: |
2025-01-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7855420 |
Age: |
embryonic day 18.5 |
Image: |
2 |
|
Specimen Label: |
Mutant |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7855268 |
Assay Type: |
Western blot |
Annotation Date: |
2025-01-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7855420 |
Age: |
embryonic day 18.5 |
Image: |
2 |
|
Specimen Label: |
Mutant |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7855268 |
Assay Type: |
Western blot |
Annotation Date: |
2025-01-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7855420 |
Age: |
embryonic day 18.5 |
Image: |
2 |
|
Specimen Label: |
Mutant |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3570528 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:6449211 |
Age: |
postnatal adult |
Image: |
4A/B |
Note: |
Punctate distribution of expression in cytoplasm, with ring of submembranous expression. No expression in germinal vesicle. |
Specimen Label: |
4A/B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:361197 |
Pattern: |
Widespread |
Stage: |
TS07 |
Assay Id: |
MGI:6449211 |
Age: |
embryonic day 5.0 |
Image: |
4E embryo |
Note: |
Expression in inner cell mass. Authors report expression in all embryonic and extraembryonic tissues. |
Specimen Label: |
4E embryo |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3538523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:6449211 |
Age: |
embryonic day 15.5 |
Image: |
7c |
Note: |
Expression in smooth muscle surrounding gut. |
Specimen Label: |
7c |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-11-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1626717 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5695584 |
Age: |
embryonic day 10.5 |
Image: |
8A |
|
Specimen Label: |
8A |
Detected: |
false |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-11-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1626720 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5695584 |
Age: |
embryonic day 12.5 |
Image: |
8B |
|
Specimen Label: |
8B |
Detected: |
false |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-11-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1626722 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5695584 |
Age: |
embryonic day 14.5 |
Image: |
8C |
|
Specimen Label: |
8C |
Detected: |
false |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-11-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1626724 |
|
Stage: |
TS24 |
Assay Id: |
MGI:5695584 |
Age: |
embryonic day 16.5 |
Image: |
8D |
|
Specimen Label: |
8D |
Detected: |
false |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3526928 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6449211 |
Age: |
postnatal adult |
Image: |
4E decidua |
Note: |
Expression in maternal decidual cells. |
Specimen Label: |
4E decidua |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-11-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1907828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5695584 |
Age: |
postnatal adult |
Image: |
2A |
Note: |
Expression is in the microvilli and terminal web in the brush border and along the basolateral membranes. |
Specimen Label: |
2A |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1907820 |
Pattern: |
Regionally restricted |
Stage: |
TS20 |
Assay Id: |
MGI:6449211 |
Age: |
embryonic day 12.5 |
Image: |
7b |
Note: |
Expression distributed in cytoplasm. |
Specimen Label: |
7b |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1907823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:6449211 |
Age: |
embryonic day 15.5 |
Image: |
7c |
Note: |
Expression concentrated in apical cytoplasm. |
Specimen Label: |
7c |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1907828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:6449211 |
Age: |
postnatal adult |
Image: |
7d |
Note: |
Expression remains concentrated in apical cytoplasm. |
Specimen Label: |
7d |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4427105 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827284 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013517_10 |
|
Specimen Label: |
euxassay_013517_10 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4427105 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827284 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013517_11 |
|
Specimen Label: |
euxassay_013517_11 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4427105 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827284 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013517_12 |
|
Specimen Label: |
euxassay_013517_12 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4427105 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827284 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013517_13 |
|
Specimen Label: |
euxassay_013517_13 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4427105 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752323 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827284 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_013517_14 |
|
Specimen Label: |
euxassay_013517_14 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-11-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1624717 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5695584 |
Age: |
embryonic day 10.5 |
Image: |
6A |
Note: |
Absent in the intestine. |
Specimen Label: |
6A |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-11-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608620 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:5695584 |
Age: |
embryonic day 12.5 |
Image: |
8B |
Note: |
Expression is along the apical membranes. |
Specimen Label: |
8B |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-11-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608622 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:5695584 |
Age: |
embryonic day 14.5 |
Image: |
8C |
Note: |
Expression is along the apical membranes. |
Specimen Label: |
8C |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-11-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608624 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:5695584 |
Age: |
embryonic day 16.5 |
Image: |
8D |
Note: |
Expression is along the apical membranes. |
Specimen Label: |
8D |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608613 |
Pattern: |
Regionally restricted |
Stage: |
TS13 |
Assay Id: |
MGI:6449211 |
Age: |
embryonic day 8.5 |
Image: |
4G |
Note: |
Expression redistributed to apical cytoplasm of visceral endoderm. |
Specimen Label: |
4G |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5812149 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-12-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1866828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:5812528 |
Age: |
postnatal |
|
Note: |
Expression is in microvilli. |
Specimen Label: |
S3 Jejunum WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5812149 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-12-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1866828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:5812528 |
Age: |
postnatal |
|
Note: |
Expression in this mutant is the same as in wild-type. |
Specimen Label: |
S3 Jejunum -/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5812149 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-12-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1894128 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:5812528 |
Age: |
postnatal |
|
Note: |
Expression is in microvilli. |
Specimen Label: |
S3 Colon WT |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5812149 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-12-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1894128 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:5812528 |
Age: |
postnatal |
|
Note: |
Expression in this mutant is the same as in wild-type. |
Specimen Label: |
S3 Colon -/- |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1885217 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:6449211 |
Age: |
embryonic day 10.5 |
Image: |
7a |
Note: |
Expression more evenly distributed throughout intestinal cells; slightly more concentrated along basal surface of epithelium. |
Specimen Label: |
7a |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3102528 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:6449211 |
Age: |
postnatal adult |
Image: |
4C/D |
Note: |
In later-stage oocytes, expression concentrated in cortical cytoplasm. |
Specimen Label: |
4C/D |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-11-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3592917 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5695584 |
Age: |
embryonic day 10.5 |
Image: |
8A |
Note: |
Expression is along the apical and basolateral membranes. |
Specimen Label: |
8A |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3592917 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:6449211 |
Age: |
embryonic day 10.5 |
Image: |
4H |
Note: |
Localization of expression to apical surface more prominent by E10.5. |
Specimen Label: |
4H |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1625013 |
Pattern: |
Diffuse |
Stage: |
TS13 |
Assay Id: |
MGI:6449211 |
Age: |
embryonic day 8.5 |
Image: |
4F |
Note: |
Diffuse cytoplasmic expression in epithelial lining of foregut. |
Specimen Label: |
4F |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-11-12 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287320 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:5695584 |
Age: |
embryonic day 12.5 |
Image: |
6B |
Note: |
Expression is at the apical surface. |
Specimen Label: |
6B |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-11-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287322 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:5695584 |
Age: |
embryonic day 14.5 |
Image: |
6C |
Note: |
Expression is strong at the apical surface and weaker at the basolateral membrane. |
Specimen Label: |
6C |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5695574 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-11-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287324 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:5695584 |
Age: |
embryonic day 16.5 |
Image: |
6D |
Note: |
Expression is in the developing microvilli and terminal web region. |
Specimen Label: |
6D |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Weak |
Sex: |
Female |
Emaps: |
EMAPS:1796228 |
Pattern: |
Diffuse |
Stage: |
TS28 |
Assay Id: |
MGI:6449211 |
Age: |
postnatal adult |
Image: |
4A/B |
Note: |
Weak, diffuse expression in follicle cell surrounding oocytes and adjacent ovarian tissues. |
Specimen Label: |
4A/B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6449100 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-08-11 |
Strength: |
Weak |
Sex: |
Female |
Emaps: |
EMAPS:1796228 |
Pattern: |
Diffuse |
Stage: |
TS28 |
Assay Id: |
MGI:6449211 |
Age: |
postnatal adult |
Image: |
4C/D |
Note: |
Weak, diffuse expression in follicle cell surrounding oocytes and adjacent ovarian tissues. |
Specimen Label: |
4C/D |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deady LE |
Year: |
2014 |
Journal: |
Infect Immun |
Title: |
L-plastin is essential for alveolar macrophage production and control of pulmonary pneumococcal infection. |
Volume: |
82 |
Issue: |
5 |
Pages: |
1982-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chafel MM |
Year: |
1995 |
Journal: |
Dev Dyn |
Title: |
Sequential expression and differential localization of I-, L-, and T-fimbrin during differentiation of the mouse intestine and yolk sac. |
Volume: |
203 |
Issue: |
2 |
Pages: |
141-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ohsawa K |
Year: |
2004 |
Journal: |
J Neurochem |
Title: |
Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity. |
Volume: |
88 |
Issue: |
4 |
Pages: |
844-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ezzell RM |
Year: |
1989 |
Journal: |
Development |
Title: |
Differential localization of villin and fimbrin during development of the mouse visceral endoderm and intestinal epithelium. |
Volume: |
106 |
Issue: |
2 |
Pages: |
407-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lutz J |
Year: |
2014 |
Journal: |
Histochem Cell Biol |
Title: |
Expression analysis of mouse Rhobtb3 using a LacZ reporter and preliminary characterization of a knockout strain. |
Volume: |
142 |
Issue: |
5 |
Pages: |
511-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morandell J |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. |
Volume: |
12 |
Issue: |
1 |
Pages: |
3058 |
|
•
•
•
•
•
|
Publication |
First Author: |
Muthu V |
Year: |
2019 |
Journal: |
Development |
Title: |
Genomic architecture of Shh-dependent cochlear morphogenesis. |
Volume: |
146 |
Issue: |
18 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Gao N |
Year: |
2010 |
Journal: |
Genes Dev |
Title: |
Cdx2 regulates endo-lysosomal function and epithelial cell polarity. |
Volume: |
24 |
Issue: |
12 |
Pages: |
1295-305 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Sequence and Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
Mouse Genome Sequence Project Annotation |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
Journal: |
Database Download |
Title: |
Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
|
|
|
|
•
•
•
•
•
|