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Search results 1 to 100 out of 327 for Rab9

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Hits by Strain

Type Details Score
Protein Domain
IPR041824 | Rab9
Type: Family
Description: Ras-related protein Rab9 is a member of the large Rab GTPase family. It is found in late endosomes, together with mannose 6-phosphate receptors (MPRs) and the tail-interacting protein of 47kDa (TIP47). Rab9 is a key mediator of vesicular transport from late endosomes to the trans-Golgi network (TGN) by redirecting the MPRs []. Rab9 has been identified as a key component for the replication of several viruses, including HIV1, Ebola, Marburg, and measles, making it a potential target for inhibiting a variety of viruses [].Rabs are regulated by GTPase activating proteins (GAPs), which interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP. Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state. Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localization. Most Rab GTPases contain a lipid modification site at the C terminus, with sequence motifs CC, CXC, or CCX. Lipid binding is essential for membrane attachment, a key feature of most Rab proteins [, ].
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Protein Coding Gene
MGI:1890695 | Rab9
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
16140752 | -
First Author: Murray JL
Year: 2005
Journal: J Virol
Title: Rab9 GTPase is required for replication of human immunodeficiency virus type 1, filoviruses, and measles virus.
Volume: 79
Issue: 18
Pages: 11742-51
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Publication
15456905 | -
First Author: Ganley IG
Year: 2004
Journal: Mol Biol Cell
Title: Rab9 GTPase regulates late endosome size and requires effector interaction for its stability.
Volume: 15
Issue: 12
Pages: 5420-30
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Protein
Q9R0M6
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
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Publication
30511961 | J:329650
First Author: Saito T
Year: 2019
Journal: J Clin Invest
Title: An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia.
Volume: 129
Issue: 2
Pages: 802-819
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Protein
Q8BHH2
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
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Protein
Q3KNA5
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
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Protein
Q0PD48
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
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Protein
A2AFP5
Organism: Mus musculus/domesticus
Length: 202  
Fragment?: true
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Publication
10196122 | -
First Author: Dumas JJ
Year: 1999
Journal: Structure
Title: Structural basis of activation and GTP hydrolysis in Rab proteins.
Volume: 7
Issue: 4
Pages: 413-23
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Publication
11387043 | -
First Author: Stenmark H
Year: 2001
Journal: Genome Biol
Title: The Rab GTPase family.
Volume: 2
Issue: 5
Pages: REVIEWS3007
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Gene
10244 | RABEPK
Type: gene
Organism: human
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Gene
100421226 | RABEPKP1
Type: gene
Organism: human
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Publication
25220469 | J:233558
First Author: Zhang Z
Year: 2014
Journal: Structure
Title: Crystal structure of the Rab9A-RUTBC2 RBD complex reveals the molecular basis for the binding specificity of Rab9A with RUTBC2.
Volume: 22
Issue: 10
Pages: 1408-20
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Publication
20048159 | J:235260
First Author: Kloer DP
Year: 2010
Journal: J Biol Chem
Title: Assembly of the biogenesis of lysosome-related organelles complex-3 (BLOC-3) and its interaction with Rab9.
Volume: 285
Issue: 10
Pages: 7794-804
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Protein Coding Gene
MGP_CAROLIEiJ_G0033573 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_AJ_G0036235 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0036165 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0036230 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035937 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1890695 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036753 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0035224 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035911 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0036077 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0036009 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0036162 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0036041 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0036792 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034923 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0035360 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0032112 | -
Type: protein_coding_gene
Organism: Mus pahari
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Publication
26620560 | J:230050
First Author: Marubashi S
Year: 2016
Journal: J Biol Chem
Title: RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes.
Volume: 291
Issue: 3
Pages: 1427-40
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Publication
15078902 | J:89488
First Author: Seaman MN
Year: 2004
Journal: J Cell Biol
Title: Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer.
Volume: 165
Issue: 1
Pages: 111-22
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Publication
12051767 | J:76617
First Author: Zhao H
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Intracellular membrane trafficking pathways in bone-resorbing osteoclasts revealed by cloning and subcellular localization studies of small GTP-binding rab proteins.
Volume: 293
Issue: 3
Pages: 1060-5
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
20548051 | J:163340
First Author: Cox BJ
Year: 2010
Journal: Genome Res
Title: Phenotypic annotation of the mouse X chromosome.
Volume: 20
Issue: 8
Pages: 1154-64
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Publication
25131634 | J:238190
First Author: Alldred MJ
Year: 2015
Journal: J Comp Neurol
Title: Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice.
Volume: 523
Issue: 1
Pages: 61-74
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Publication
- | J:160967
     
First Author: Cox BJ
Year: 2010
Journal: MGI Direct Data Submission
Title: Phenotypic annotation of the mouse X chromosome
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
15760467 | J:99477
 
First Author: Brown AC
Year: 2005
Journal: BMC Genet
Title: Searching QTL by gene expression: analysis of diabesity.
Volume: 6
Pages: 12
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:66348
   
First Author: Seki N
Year: 1999
Journal: GenBank Submission
Title: Mus musculus SID 99 mRNA for small GTP binding protein, complete cds
Pages: AB027290
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Publication
14530284 | J:292523
First Author: Ikonomov OC
Year: 2003
Journal: J Biol Chem
Title: Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40.
Volume: 278
Issue: 51
Pages: 50863-71
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Publication
9126495 | J:40089
First Author: Davies JP
Year: 1997
Journal: Genomics
Title: Cloning and mapping of human Rab7 and Rab9 cDNA sequences and identification of a Rab9 pseudogene.
Volume: 41
Issue: 1
Pages: 131-4
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Protein Coding Gene
MGI:2139530 | Rabepk
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
19056848 | J:144240
First Author: Kaptzan T
Year: 2009
Journal: Am J Pathol
Title: Development of a Rab9 transgenic mouse and its ability to increase the lifespan of a murine model of Niemann-Pick type C disease.
Volume: 174
Issue: 1
Pages: 14-20
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Gene
296649 | Rabepk
Type: gene
Organism: rat
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Gene
738599 | RABEPK
Type: gene
Organism: chimpanzee
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Gene
609581 | RABEPK
Type: gene
Organism: dog, domestic
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Gene
533613 | RABEPK
Type: gene
Organism: cattle
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Gene
100859020 | LOC100859020
Type: gene
Organism: chicken
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Gene
772357 | RABEPK
Type: gene
Organism: chicken
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Gene
431756 | rabepk
Type: gene
Organism: zebrafish
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Gene
712731 | RABEPK
Type: gene
Organism: macaque, rhesus
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Gene
102152427 | LOC102152427
Type: gene
Organism: dog, domestic
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Gene
100492747 | rabepk
Type: gene
Organism: frog, western clawed
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Gene
100145144 | XB5901661
Type: gene
Organism: frog, western clawed
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Gene
447194 | rabepk.L
Type: gene
Organism: frog, African clawed
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UniProt Feature
UniProt Feature
Begin: 1
Description: Rab9 effector protein with kelch motifs
Type: chain
End: 380
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Publication
30837268 | J:278183
First Author: Ohishi Y
Year: 2019
Journal: J Biol Chem
Title: The BLOC-3 subunit HPS4 is required for activation of Rab32/38 GTPases in melanogenesis, but its Rab9 activity is dispensable for melanogenesis.
Volume: 294
Issue: 17
Pages: 6912-6922
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Gene
100126636 | XB5901661.S
Type: gene
Organism: frog, African clawed
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Protein
Q8VCH5
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
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Protein
D6RHN6
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: false
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Protein
D6RGR6
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: false
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Protein
G8JL41
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: true
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Protein
A2AUF7
Organism: Mus musculus/domesticus
Length: 321  
Fragment?: false
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Protein
B0R0S4
Organism: Mus musculus/domesticus
Length: 372  
Fragment?: false
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Allele
Rabepk<+> | MGI:3580828
 
Name: Rab9 effector protein with kelch motifs; wild type
Allele Type: Not Specified
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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