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Search results 1 to 100 out of 106 for Rcan3

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Hits by Category

Hits by Strain

Type Details Score
Gene
11123 | RCAN3
Type: gene
Organism: human
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Gene
100124707 | rcan3
Type: gene
Organism: frog, western clawed
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Gene
362627 | Rcan3
Type: gene
Organism: rat
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Gene
487369 | RCAN3
Type: gene
Organism: dog, domestic
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Gene
456631 | RCAN3
Type: gene
Organism: chimpanzee
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Gene
506601 | RCAN3
Type: gene
Organism: cattle
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Gene
419698 | RCAN3
Type: gene
Organism: chicken
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Gene
325356 | rcan3
Type: gene
Organism: zebrafish
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Gene
719315 | RCAN3
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR034923 | RCAN3
Type: Family
Description: Calcipressin-3 (RCAN3) is a member of the calcipressin family. Overexpressed RCAN3 has been found to bind and inhibit the Ca2+/calmodulin-dependent phosphatase calcineurin, and further down-regulates nuclear factor of activated T cells (NFAT)-dependent cytokine gene expression in activated human Jurkat T cells []. RCAN3 can also interact with cardiac troponin I (TNNI3), a heart-specific inhibitory subunit of the troponin complex, and may play a role in cardiac contraction [].Calcipressins (RCANs) are a novel family of calcineurin regulators that have been suggested as key factors contributing to Down syndrome in humans. Three human calcipressins have been identified, calcipressin 1-3. Calcipressin 1 is also known as modulatory calcineurin-interacting protein 1 (MCIP1), Adapt78 and Down syndrome critical region 1 (DSCR1). Calcipressin 2 is variously known as MCIP2, ZAKI-4 and DSCR1-like 1. Calcipressin 3 is also called MCIP3 and DSCR1-like 2 []. Calcipressins contain an N-terminal RNA recognition motif (RRM), a highly conserved SP repeat domain containing the phosphorylation site by GSK-3, a well-known PxIxIT motif responsible for docking many substrates to calcineurin, and a C-terminal TxxP motif [].Calcineurin is a calcium-responsive enzyme that dephosphorylates the nuclear factor of activated T cells (NFAT). In doing so, it promotes its nuclear translocation and uniquely links calcium signalling to transcriptional regulation [].
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Protein Coding Gene
MGI:1858220 | Rcan3
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100750325 | RCAN3AS
Type: gene
Organism: human
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Publication
18022329 | -
First Author: Facchin F
Year: 2008
Journal: Gene
Title: Identification and analysis of human RCAN3 (DSCR1L2) mRNA and protein isoforms.
Volume: 407
Issue: 1-2
Pages: 159-68
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Publication
17270291 | -
First Author: Mulero MC
Year: 2007
Journal: Biochim Biophys Acta
Title: RCAN3, a novel calcineurin inhibitor that down-regulates NFAT-dependent cytokine gene expression.
Volume: 1773
Issue: 3
Pages: 330-41
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Protein
Q9JKK0
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: false
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Protein
B0QZL9
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: true
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Protein
A2A994
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: true
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Publication
12942079 | -
First Author: Parry RV
Year: 2003
Journal: Nat Immunol
Title: Calcium-independent calcineurin regulation.
Volume: 4
Issue: 9
Pages: 821-3
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Publication
19273587 | -
First Author: Mehta S
Year: 2009
Journal: Mol Cell Biol
Title: Domain architecture of the regulators of calcineurin (RCANs) and identification of a divergent RCAN in yeast.
Volume: 29
Issue: 10
Pages: 2777-93
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Publication
25783055 | J:309990
First Author: Serrano-Candelas E
Year: 2015
Journal: Biochem Biophys Res Commun
Title: RCAN 1 and 3 proteins regulate thymic positive selection.
Volume: 460
Issue: 2
Pages: 295-301
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Protein Coding Gene
MGP_CAROLIEiJ_G0026638 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028943 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028902 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028854 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028926 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028640 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1858220 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029367 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028072 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028605 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028754 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028721 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028853 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028747 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029405 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027792 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028150 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028971 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0027618 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:2669980
Assay Type: Northern blot
Annotation Date: 2003-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2669984
Age: postnatal adult
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2669980
Assay Type: Northern blot
Annotation Date: 2003-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2669984
Age: postnatal adult
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2669980
Assay Type: Northern blot
Annotation Date: 2003-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2669984
Age: postnatal adult
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2669980
Assay Type: Northern blot
Annotation Date: 2003-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2669984
Age: postnatal adult
Specimen Label: 4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2669980
Assay Type: Northern blot
Annotation Date: 2003-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2669984
Age: postnatal adult
Specimen Label: 5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:2669980
Assay Type: Northern blot
Annotation Date: 2003-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2669984
Age: postnatal adult
Specimen Label: 6
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:2669980
Assay Type: Northern blot
Annotation Date: 2003-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2669984
Age: postnatal adult
Specimen Label: 7
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:2669980
Assay Type: Northern blot
Annotation Date: 2003-08-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2669984
Age: postnatal adult
Specimen Label: 8
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:2669980
Assay Type: Northern blot
Annotation Date: 2003-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2669985
Age: embryonic day 7.0
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2669980
Assay Type: Northern blot
Annotation Date: 2003-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2669985
Age: embryonic day 11.0
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2669980
Assay Type: Northern blot
Annotation Date: 2003-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2669985
Age: embryonic day 15.0
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2669980
Assay Type: Northern blot
Annotation Date: 2003-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2669985
Age: embryonic day 17.0
Specimen Label: 4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3618790
Assay Type: RT-PCR
Annotation Date: 2006-04-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Stage: TS28
Assay Id: MGI:3618803
Age: postnatal adult
Specimen Label: Dscr1l2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3708297
Assay Type: RT-PCR
Annotation Date: 2007-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:3708373
Age: embryonic day 13.5
Image: 7
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3708297
Assay Type: RT-PCR
Annotation Date: 2007-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:3708373
Age: embryonic day 16.5
Image: 7
Specimen Label: E16.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7485878
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:7485936
Age: postnatal adult
Specimen Label: Thymus
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7485878
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3552328
Stage: TS28
Assay Id: MGI:7485936
Age: postnatal adult
Specimen Label: LN
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7485878
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7485936
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7485878
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:7485936
Age: postnatal adult
Specimen Label: BM
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7485878
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7485936
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:7485878
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876824
Stage: TS24
Assay Id: MGI:7485941
Age: embryonic day 16.0
Specimen Label: Thymus E16
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7485878
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:7485941
Age: embryonic day 16.0
Specimen Label: Liver E16
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7485869
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7486041
Age: postnatal week 8-15
Specimen Label: hnRNP A1<+/+>
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7485869
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7486041
Age: postnatal week 8-15
Specimen Label: hnRNP A1<+/->
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7485869
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7486040
Age: postnatal week 8-15
Specimen Label: hnRNP A1<+/+>
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7485869
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7486040
Age: postnatal week 8-15
Specimen Label: hnRNP A1<+/->
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7485869
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:7486042
Age: postnatal week 8-15
Specimen Label: hnRNP A1<+/+>
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7485869
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:7486042
Age: postnatal week 8-15
Specimen Label: hnRNP A1<+/->
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7485878
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:7485941
Age: postnatal adult
Specimen Label: Thymus Adult
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3618775
Assay Type: RNA in situ
Annotation Date: 2006-04-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3618785
Age: embryonic day 18.5
Note: Expression is in the acruate nucleus, the dorsal medial and ventromedial hypothalamus.
Specimen Label: Dscr1l2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:2453559
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Pattern: Ubiquitous
Stage: TS23
Assay Id: MGI:4827662
Age: embryonic day 14.5
Image: euxassay_010962_15
Specimen Label: euxassay_010962_15
Detected: true
Specimen Num: 1
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Publication
11080588 | J:65855
First Author: Strippoli P
Year: 2000
Journal: Gene
Title: The murine DSCR1-like (Down syndrome candidate region 1) gene family: conserved synteny with the human orthologous genes.
Volume: 257
Issue: 2
Pages: 223-32
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Publication
10756093 | J:61529
First Author: Strippoli P
Year: 2000
Journal: Genomics
Title: A new gene family including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2).
Volume: 64
Issue: 3
Pages: 252-63
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Publication
17595344 | J:122065
First Author: Davies KJ
Year: 2007
Journal: FASEB J
Title: Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin.
Volume: 21
Issue: 12
Pages: 3023-8
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Publication
15870395 | J:100830
First Author: Bischof JM
Year: 2005
Journal: Physiol Genomics
Title: Genome-wide analysis of gene transcription in the hypothalamus.
Volume: 22
Issue: 2
Pages: 191-6
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Publication
28077597 | J:238260
 
First Author: Liu TY
Year: 2017
Journal: Open Biol
Title: Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice.
Volume: 7
Issue: 1
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Publication
17198697 | J:119549
First Author: Yang XY
Year: 2007
Journal: Dev Biol
Title: Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition.
Volume: 303
Issue: 2
Pages: 825-37
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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