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Search results 1 to 100 out of 1043 for Robo1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
6091 | ROBO1
Type: gene
Organism: human
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Gene
100124716 | robo1
Type: gene
Organism: frog, western clawed
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Gene
58946 | Robo1
Type: gene
Organism: rat
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Gene
487690 | ROBO1
Type: gene
Organism: dog, domestic
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Gene
460518 | ROBO1
Type: gene
Organism: chimpanzee
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Gene
536815 | ROBO1
Type: gene
Organism: cattle
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Gene
395292 | ROBO1
Type: gene
Organism: chicken
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Gene
30769 | robo1
Type: gene
Organism: zebrafish
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Gene
722879 | ROBO1
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR032986 | Robo1
Type: Family
Description: The secreted Slit repellents and their Roundabout (Robo) receptors were originally identified as important axon guidance molecules. The SLIT-ROBO interaction has been found to be involved in the regulation of cell migration, cell death and angiogenesis and, as such, has a pivotal role during the development of other tissues such as the lung, kidney, liver and breast []. There are four Robo homologues in vertebrates (Robo1-4).Robo1 and Robo2 are known to play a crucial role in axon guidance [, ]. They overlap to cooperate in guiding longitudinal axons, but each isoform has specialised functions in spinal commissural axon guidance [, ]. Robo1 prevents axonal stalling after crossing []. Robo1 may also be involved in lung []and heart development [, ].Deregulation of Robo is implicated in several neuropathological conditions and cancers [].
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Protein Coding Gene
MGI:1274781 | Robo1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
21820427 | J:176600
First Author: Kim M
Year: 2011
Journal: Dev Biol
Title: Robo1 and Robo2 have distinct roles in pioneer longitudinal axon guidance.
Volume: 358
Issue: 1
Pages: 181-8
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Publication
17360927 | J:119469
First Author: Fouquet C
Year: 2007
Journal: J Neurosci
Title: Robo1 and robo2 control the development of the lateral olfactory tract.
Volume: 27
Issue: 11
Pages: 3037-45
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Publication
20631173 | J:162558
First Author: Jaworski A
Year: 2010
Journal: J Neurosci
Title: Collaborative and specialized functions of Robo1 and Robo2 in spinal commissural axon guidance.
Volume: 30
Issue: 28
Pages: 9445-53
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Publication
11734623 | J:73485
First Author: Xian J
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene.
Volume: 98
Issue: 26
Pages: 15062-6
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Publication
15091338 | J:89780
First Author: Long H
Year: 2004
Journal: Neuron
Title: Conserved roles for Slit and Robo proteins in midline commissural axon guidance.
Volume: 42
Issue: 2
Pages: 213-23
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Publication
25691540 | J:244269
First Author: Mommersteeg MT
Year: 2015
Journal: Cardiovasc Res
Title: Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves.
Volume: 106
Issue: 1
Pages: 55-66
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Publication
20941780 | J:166534
First Author: Medioni C
Year: 2010
Journal: Dev Dyn
Title: Expression of Slit and Robo genes in the developing mouse heart.
Volume: 239
Issue: 12
Pages: 3303-11
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450760
Age: embryonic day 16.5
Image: Robo1 - E16.5
Note: There is strong staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Robo1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450760
Age: embryonic day 12.5
Image: Robo1 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Robo1 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450760
Age: embryonic day 14.5
Image: Robo1 - E14.5
Note: There is moderate staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Robo1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754324
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450760
Age: embryonic day 16.5
Image: Robo1 - E16.5
Note: There is strong staining in the ventricular zone of the prethalamus. Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus.
Specimen Label: Robo1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Pattern: Widespread
Stage: TS21
Assay Id: MGI:6188844
Age: embryonic day 13.5
Image: 1 Robo1 E13.5 Rostral
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E13.5 Rostral
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:6188844
Age: embryonic day 15.5
Image: 1 Robo1 E15.5 Rostral
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E15.5 Rostral
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:6188844
Age: embryonic day 15.5
Image: 1 Robo1 E15.5 Caudal
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E15.5 Caudal
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Pattern: Widespread
Stage: TS25
Assay Id: MGI:6188844
Age: embryonic day 17.5
Image: 1 Robo1 E17.5 Caudal
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E17.5 Caudal
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753720
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450760
Age: embryonic day 12.5
Image: Robo1 - E12.5
Note: There is strong staining in the mantle zone of the VMH nucleus and weak staining in the dorsal and ventral POAs. Staining is either absent or ubiquitous in the mantle zone of the PVH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Robo1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753722
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450760
Age: embryonic day 14.5
Image: Robo1 - E14.5
Note: There is moderate staining in the MZ of the dorsal and ventral POAs and the AVH and weak staining in the PVH nucleus. Staining is either absent or ubiquitous in the MZ of the anterior and posterior IDs, the VMH and ARH nuclei and the AVH.
Specimen Label: Robo1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753724
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450760
Age: embryonic day 16.5
Image: Robo1 - E16.5
Note: There is moderate staining in the mantle zone of the dorsal and ventral POAs and weak staining in the AVH and the DAH. Staining is either absent or ubiquitous in the mantle zone of the PVH, SCH, DMH, VMH and ARH nuclei and the PH.
Specimen Label: Robo1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450760
Age: embryonic day 11.5
Image: Robo1 - E11.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex and the ganglionic eminences.
Specimen Label: Robo1 - E11.5
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267323
Pattern: Widespread
Stage: TS23
Assay Id: MGI:6188844
Age: embryonic day 15.5
Image: 1 Robo1 E15.5 Caudal
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E15.5 Caudal
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267325
Pattern: Widespread
Stage: TS25
Assay Id: MGI:6188844
Age: embryonic day 17.5
Image: 1 Robo1 E17.5 Caudal
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E17.5 Caudal
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271824
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450760
Age: embryonic day 16.5
Image: Robo1 - E16.5
Note: There is weak staining in the mantle zone of the mam and supramam zones. Staining is either absent or ubiquitous in the mantle zone of the premam zone.
Specimen Label: Robo1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753920
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450760
Age: embryonic day 12.5
Image: Robo1 - E12.5
Note: There is weak staining in the ventricular zone of the anterior and posterior IDs. Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei and the AVH.
Specimen Label: Robo1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691119
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450760
Age: embryonic day 11.5
Image: Robo1 - E11.5
Note: There is strong staining in the mantle zone of the ganglionic eminences. Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex
Specimen Label: Robo1 - E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450760
Age: embryonic day 14.5
Image: Robo1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Label: Robo1 - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450760
Age: embryonic day 14.5
Image: Robo1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Label: Robo1 - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3266524
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450760
Age: embryonic day 16.5
Image: Robo1 - E16.5
Note: There is strong staining in the mantle zone of the ganglionic eminences. Staining is either absent or ubiquitous in the ventricular zone of the ganglionic eminences.
Specimen Label: Robo1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1754120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450760
Age: embryonic day 12.5
Image: Robo1 - E12.5
Note: There is very strong staining in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Robo1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754122
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450760
Age: embryonic day 14.5
Image: Robo1 - E14.5
Note: There is strong staining in the mantle zone of the dorsal thalamus. Staining is either absent or ubiquitous in the mantle zone of the prethalamus.
Specimen Label: Robo1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450760
Age: embryonic day 16.5
Image: Robo1 - E16.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Robo1 - E16.5
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3694936
Assay Type: RNA in situ
Annotation Date: 2007-02-08
Strength: Present
Sex: Female
Emaps: EMAPS:1796220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3696044
Age: embryonic day 12.0
Image: 3 Robo1 XX-/-
Specimen Label: 3 Robo1 XX-/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3747121
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6188844
Age: embryonic day 13.5
Image: 1 Robo1 E13.5 Middle
Note: Strong expression throughout mantle zone of medial ganglionic eminence.
Specimen Label: 1 Robo1 E13.5 Middle
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450760
Age: embryonic day 12.5
Image: Robo1 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Robo1 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450760
Age: embryonic day 14.5
Image: Robo1 - E14.5
Note: There is moderate staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Robo1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450760
Age: embryonic day 16.5
Image: Robo1 - E16.5
Note: There is strong staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Robo1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450760
Age: embryonic day 12.5
Image: Robo1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Robo1 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450760
Age: embryonic day 14.5
Image: Robo1 - E14.5
Note: There is strong staining in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Robo1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:6188844
Age: embryonic day 15.5
Image: 1 Robo1 E15.5 Middle
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E15.5 Middle
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Pattern: Widespread
Stage: TS25
Assay Id: MGI:6188844
Age: embryonic day 17.5
Image: 1 Robo1 E17.5 Rostral
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E17.5 Rostral
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Pattern: Widespread
Stage: TS25
Assay Id: MGI:6188844
Age: embryonic day 17.5
Image: 1 Robo1 E17.5 Middle
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E17.5 Middle
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691021
Pattern: Widespread
Stage: TS21
Assay Id: MGI:6188844
Age: embryonic day 13.5
Image: 1 Robo1 E13.5 Caudal
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E13.5 Caudal
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3694936
Assay Type: RNA in situ
Annotation Date: 2007-02-08
Strength: Present
Sex: Male
Emaps: EMAPS:2909820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:3696044
Age: embryonic day 12.0
Image: 3 Robo1 XY+/+
Note: Expression is in the testis cords.
Specimen Label: 3 Robo1 XY+/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267323
Pattern: Widespread
Stage: TS23
Assay Id: MGI:6188844
Age: embryonic day 15.5
Image: 1 Robo1 E15.5 Rostral
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E15.5 Rostral
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267323
Pattern: Widespread
Stage: TS23
Assay Id: MGI:6188844
Age: embryonic day 15.5
Image: 1 Robo1 E15.5 Middle
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E15.5 Middle
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267325
Pattern: Widespread
Stage: TS25
Assay Id: MGI:6188844
Age: embryonic day 17.5
Image: 1 Robo1 E17.5 Rostral
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E17.5 Rostral
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267325
Pattern: Widespread
Stage: TS25
Assay Id: MGI:6188844
Age: embryonic day 17.5
Image: 1 Robo1 E17.5 Middle
Note: Authors report expression throughout the rostral-caudal extend of differentiating basal ganglia and cortex.
Specimen Label: 1 Robo1 E17.5 Middle
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271820
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450760
Age: embryonic day 12.5
Image: Robo1 - E12.5
Note: There is strong staining in the mantle zone of the TT and mam zone and weak staining in the supramam zone. Staining is either absent or ubiquitous in the mantle zone of the premam zone.
Specimen Label: Robo1 - E12.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271822
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450760
Age: embryonic day 14.5
Image: Robo1 - E14.5
Note: There is strong staining in the mantle zone of the TT and the mam zone and weak staining in the supramam zone. Staining is either absent or ubiquitous in the mantle zone of the premam zone.
Specimen Label: Robo1 - E14.5
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1690819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450760
Age: embryonic day 11.5
Image: Robo1 - E11.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus, the prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
Specimen Label: Robo1 - E11.5
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753922
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450760
Age: embryonic day 14.5
Image: Robo1 - E14.5
Note: There is weak staining in the ventricular zone of the AVH and anterior and posterior IDs. Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs and the PVH, VMH and ARH nuclei.
Specimen Label: Robo1 - E14.5
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753924
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450760
Age: embryonic day 16.5
Image: Robo1 - E16.5
Note: There is strong staining in the VZ of the VMH nucleus & the PH, moderate staining in the AVH, the DAH & DMH nucleus & weak staining in the PVH nucleus. Staining is either absent or ubiquitous in the VZ of the dorsal & ventral POAs & SCH & ARH nuclei.
Specimen Label: Robo1 - E16.5
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450760
Age: embryonic day 12.5
Image: Robo1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Label: Robo1 - E12.5
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450760
Age: embryonic day 16.5
Image: Robo1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Label: Robo1 - E16.5
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450760
Age: embryonic day 12.5
Image: Robo1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Label: Robo1 - E12.5
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271024
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450760
Age: embryonic day 16.5
Image: Robo1 - E16.5
Note: There is strong staining in the ventricular zone of the premam and mam zones. Staining is either absent or ubiquitous in the ventricular zone of the supramam zone.
Specimen Label: Robo1 - E16.5
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3266520
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450760
Age: embryonic day 12.5
Image: Robo1 - E12.5
Note: There is very strong staining in the mantle zone of the ganglionic eminences. Staining is either absent or ubiquitous in the ventricular zone of the ganglionic eminences.
Specimen Label: Robo1 - E12.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3266522
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450760
Age: embryonic day 14.5
Image: Robo1 - E14.5
Note: There is moderate staining in the mantle zone of the ganglionic eminences. Staining is either absent or ubiquitous in the ventricular zone of the ganglionic eminences.
Specimen Label: Robo1 - E14.5
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3585021
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690619
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450760
Age: embryonic day 11.5
Image: Robo1 - E11.5
Note: Staining is strong in the MZ of the dorsal thalamus, prethalamus, dorsal & ventral POAs, PVH nucleus & AVH, moderate in the mam & supramam zones, weak in anterior & posterior IDs & either absent or ubiquitous in the VMH & ARH nuclei, premam zone & TT.
Specimen Label: Robo1 - E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3694936
Assay Type: RNA in situ
Annotation Date: 2007-02-08
Strength: Absent
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:3696044
Age: embryonic day 12.0
Image: 3 Robo1 XX+/+
Specimen Label: 3 Robo1 XX+/+
Detected: false
Specimen Num: 2
•
•
•
•
•
Publication
24741061 | J:210623
First Author: Yeh ML
Year: 2014
Journal: J Neurosci
Title: Robo1 modulates proliferation and neurogenesis in the developing neocortex.
Volume: 34
Issue: 16
Pages: 5717-31
•
•
•
•
•
Publication
22588058 | -
 
First Author: Ballard MS
Year: 2012
Journal: Adv Cancer Res
Title: A roundabout way to cancer.
Volume: 114
Pages: 187-235
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6188844
Age: embryonic day 15.5
Note: Strong expression in tangential migratory routes of interneurons, especially within intermediate zone/subventricular zone.
Specimen Label: Robo1 E15.5
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6188844
Age: embryonic day 17.5
Specimen Label: Robo1 E17.5
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6188844
Age: embryonic day 15.5
Note: Strong expression in tangential migratory routes of interneurons, especially within intermediate zone/subventricular zone.
Specimen Label: Robo1 E15.5
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6188844
Age: embryonic day 15.5
Note: Strong expression in preplate layer.
Specimen Label: Robo1 E15.5
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691025
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6188844
Age: embryonic day 17.5
Note: Expression somewhat downregulated in ventral telencephalon.
Specimen Label: Robo1 E17.5
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6188844
Age: embryonic day 15.5
Specimen Label: Robo1 E15.5
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5752975
Assay Type: Immunohistochemistry
Annotation Date: 2018-07-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6188844
Age: embryonic day 15.5
Specimen Label: Robo1 E15.5
Detected: true
Specimen Num: 7
•
•
•
•
•
Publication
20100881 | -
First Author: Dickinson RE
Year: 2010
Journal: Reproduction
Title: The SLIT-ROBO pathway: a regulator of cell function with implications for the reproductive system.
Volume: 139
Issue: 4
Pages: 697-704
•
•
•
•
•
Publication
25894826 | J:228373
First Author: Rama N
Year: 2015
Journal: Nat Med
Title: Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization.
Volume: 21
Issue: 5
Pages: 483-91
•
•
•
•
•
Publication
22772332 | J:190078
First Author: Mire E
Year: 2012
Journal: Nat Neurosci
Title: Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth.
Volume: 15
Issue: 8
Pages: 1134-43
•
•
•
•
•
Publication
37149867 | J:336857
First Author: Dailey-Krempel B
Year: 2023
Journal: Cell Rep
Title: A tug of war between DCC and ROBO1 signaling during commissural axon guidance.
Volume: 42
Issue: 5
Pages: 112455
•
•
•
•
•
Publication
22661412 | J:210150
First Author: Gonda Y
Year: 2013
Journal: Cereb Cortex
Title: Robo1 regulates the migration and laminar distribution of upper-layer pyramidal neurons of the cerebral cortex.
Volume: 23
Issue: 6
Pages: 1495-508
•
•
•
•
•
Protein
A0A338P6U2
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: true
•
•
•
•
•
Protein
Q3V357
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: false
•
•
•
•
•
Publication
16690755 | J:109478
First Author: Andrews W
Year: 2006
Journal: Development
Title: Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain.
Volume: 133
Issue: 11
Pages: 2243-52
•
•
•
•
•
Publication
22457488 | J:183861
First Author: Marcos-Mondéjar P
Year: 2012
Journal: J Neurosci
Title: The lhx2 transcription factor controls thalamocortical axonal guidance by specific regulation of robo1 and robo2 receptors.
Volume: 32
Issue: 13
Pages: 4372-85
•
•
•
•
•
Publication
17392456 | J:120131
First Author: López-Bendito G
Year: 2007
Journal: J Neurosci
Title: Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain.
Volume: 27
Issue: 13
Pages: 3395-407
•
•
•
•
•
Protein
Q3UUE8
Organism: Mus musculus/domesticus
Length: 293  
Fragment?: true
•
•
•
•
•
Protein
Q3UQW4
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
•
•
•
•
•
Protein
Q3UQ03
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: true
•
•
•
•
•
Publication
21508241 | J:171602
First Author: Hernández-Miranda LR
Year: 2011
Journal: J Neurosci
Title: Robo1 regulates semaphorin signaling to guide the migration of cortical interneurons through the ventral forebrain.
Volume: 31
Issue: 16
Pages: 6174-87
•
•
•
•
•
Protein
O89026
Organism: Mus musculus/domesticus
Length: 1612  
Fragment?: false
•
•
•
•
•
Protein
A0A338P6F7
Organism: Mus musculus/domesticus
Length: 1622  
Fragment?: true
•
•
•
•
•
Protein
G5E843
Organism: Mus musculus/domesticus
Length: 1612  
Fragment?: false
•
•
•
•
•
Publication
30685539 | J:276179
 
First Author: Gruner HN
Year: 2019
Journal: Neuroscience
Title: Robo1 and 2 Repellent Receptors Cooperate to Guide Facial Neuron Cell Migration and Axon Projections in the Embryonic Mouse Hindbrain.
Volume: 402
Pages: 116-129
•
•
•
•
•
Publication
36002265 | J:352718
First Author: Gorla M
Year: 2022
Journal: J Neurosci
Title: A Nedd4 E3 Ubiquitin Ligase Pathway Inhibits Robo1 Repulsion and Promotes Commissural Axon Guidance across the Midline.
Volume: 42
Issue: 40
Pages: 7547-7561
•
•
•
•
•
Publication
17826360 | J:126306
First Author: Nural HF
Year: 2007
Journal: Gene Expr Patterns
Title: The Slit receptor Robo1 is predominantly expressed via the Dutt1 alternative promoter in pioneer neurons in the embryonic mouse brain and spinal cord.
Volume: 7
Issue: 8
Pages: 837-45
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6182408
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191218
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Robo1
Detected: true
Specimen Num: 7
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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