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Search results 1 to 100 out of 110 for Rph3a

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Hits by Strain

Type Details Score
Gene
22895 | RPH3A
Type: gene
Organism: human
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Gene
100487950 | rph3a
Type: gene
Organism: frog, western clawed
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Gene
282044 | RPH3A
Type: gene
Organism: cattle
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Gene
171039 | Rph3a
Type: gene
Organism: rat
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Gene
611038 | RPH3A
Type: gene
Organism: dog, domestic
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Gene
738818 | RPH3A
Type: gene
Organism: chimpanzee
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Gene
416886 | RPH3A
Type: gene
Organism: chicken
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Gene
712197 | RPH3A
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR028698 | RPH3A
Type: Family
Description: In humans, Rabphilin-3A (RPH3A) contains two C2 domains and one RabBD (Rab-binding) domain. RPH3A may interact with the SNARE complex and regulate synaptic vesicle exocytosis and Ca2+-triggered neurotransmitter release []. It has been linked to neurodegenerative diseases, such as Huntington's disease [], Lewy body disease []and Alzheimer's disease [].
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Protein Coding Gene
MGI:102788 | Rph3a
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:3639882
Assay Type: RNA in situ
Annotation Date: 2006-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3639926
Age: embryonic day 14.5
Note: Expression was detected in the inferior olivary nucleus (ION).
Specimen Label: 6P Rph3a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3639882
Assay Type: RNA in situ
Annotation Date: 2006-08-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1755022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3639926
Age: embryonic day 14.5
Note: Expression was detected in the inferior olivary nucleus (ION) as in wild type, but the area of the ION was increased.
Specimen Label: 6P Rph3a
Detected: true
Specimen Num: 2
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Publication
28636945 | J:254711
First Author: Yuan Q
Year: 2017
Journal: Cell Rep
Title: PKN1 Directs Polarized RAB21 Vesicle Trafficking via RPH3A and Is Important for Neutrophil Adhesion and Ischemia-Reperfusion Injury.
Volume: 19
Issue: 12
Pages: 2586-2597
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Publication
17877635 | -
First Author: Smith R
Year: 2007
Journal: J Neurochem
Title: Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease.
Volume: 103
Issue: 1
Pages: 115-23
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Publication
15207266 | -
First Author: Dalfó E
Year: 2004
Journal: Neurobiol Dis
Title: Abnormal alpha-synuclein interactions with rab3a and rabphilin in diffuse Lewy body disease.
Volume: 16
Issue: 1
Pages: 92-7
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Publication
24200817 | -
 
First Author: Tan MG
Year: 2014
Journal: Neurochem Int
Title: Decreased rabphilin 3A immunoreactivity in Alzheimer's disease is associated with Aβ burden.
Volume: 64
Pages: 29-36
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Protein
A0A0J9YV12
Organism: Mus musculus/domesticus
Length: 49  
Fragment?: true
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Protein
P47708
Organism: Mus musculus/domesticus
Length: 681  
Fragment?: false
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Protein
Q768S5
Organism: Mus musculus/domesticus
Length: 681  
Fragment?: false
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Publication
26679993 | J:228276
 
First Author: Stanic J
Year: 2015
Journal: Nat Commun
Title: Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex.
Volume: 6
Pages: 10181
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Protein Coding Gene
MGP_CAROLIEiJ_G0027676 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030021 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029986 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029924 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029997 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029715 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_102788 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030450 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029123 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029684 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029834 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029791 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029923 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029821 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030491 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028837 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029198 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024256 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028674 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:4884891
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944986
Age: embryonic day 11.5
Image: g00427 E11.5
Specimen Label: g00427 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4884891
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944986
Age: embryonic day 11.5
Image: g00427 E11.5
Specimen Label: g00427 E11.5
Detected: true
Specimen Num: 1
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Publication
35398339 | J:325659
 
First Author: Sekine Y
Year: 2022
Journal: Exp Neurol
Title: Rabphilin3A reduces integrin-dependent growth cone signaling to restrict axon regeneration after trauma.
Volume: 353
Pages: 114070
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Publication
7822236 | J:20188
First Author: Inagaki N
Year: 1994
Journal: J Biochem
Title: Cloning of a mouse Rabphilin-3A expressed in hormone-secreting cells.
Volume: 116
Issue: 2
Pages: 239-42
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Publication
10407024 | J:56293
First Author: Schlüter OM
Year: 1999
Journal: J Neurosci
Title: Rabphilin knock-out mice reveal that rabphilin is not required for rab3 function in regulating neurotransmitter release.
Volume: 19
Issue: 14
Pages: 5834-46
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Publication
10707984 | J:60150
First Author: Fenster SD
Year: 2000
Journal: Neuron
Title: Piccolo, a presynaptic zinc finger protein structurally related to bassoon.
Volume: 25
Issue: 1
Pages: 203-14
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Publication
10025402 | J:52577
First Author: Ostermeier C
Year: 1999
Journal: Cell
Title: Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A.
Volume: 96
Issue: 3
Pages: 363-74
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Publication
15967669 | J:104634
First Author: Smith R
Year: 2005
Journal: Neurobiol Dis
Title: Depletion of rabphilin 3A in a transgenic mouse model (R6/1) of Huntington's disease, a possible culprit in synaptic dysfunction.
Volume: 20
Issue: 3
Pages: 673-84
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Publication
30930167 | J:284160
First Author: Ren C
Year: 2019
Journal: Dev Cell
Title: Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment.
Volume: 49
Issue: 2
Pages: 206-219.e7
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Publication
16763567 | J:326633
First Author: Deák F
Year: 2006
Journal: EMBO J
Title: Rabphilin regulates SNARE-dependent re-priming of synaptic vesicles for fusion.
Volume: 25
Issue: 12
Pages: 2856-66
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Publication
16043482 | J:114721
First Author: Baldini G
Year: 2005
Journal: J Biol Chem
Title: Rabphilin localizes with the cell actin cytoskeleton and stimulates association of granules with F-actin cross-linked by {alpha}-actinin.
Volume: 280
Issue: 41
Pages: 34974-84
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Publication
22993210 | J:200268
First Author: Brozzi F
Year: 2012
Journal: Mol Biol Cell
Title: MyRIP interaction with MyoVa on secretory granules is controlled by the cAMP-PKA pathway.
Volume: 23
Issue: 22
Pages: 4444-55
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Publication
14722103 | J:166024
First Author: Fukuda M
Year: 2004
Journal: J Biol Chem
Title: Rabphilin and Noc2 are recruited to dense-core vesicles through specific interaction with Rab27A in PC12 cells.
Volume: 279
Issue: 13
Pages: 13065-75
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Publication
21521611 | J:174823
First Author: Pang ZP
Year: 2011
Journal: Neuron
Title: Doc2 supports spontaneous synaptic transmission by a Ca(2+)-independent mechanism.
Volume: 70
Issue: 2
Pages: 244-51
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Publication
31235931 | J:281603
First Author: Avagliano Trezza R
Year: 2019
Journal: Nat Neurosci
Title: Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome.
Volume: 22
Issue: 8
Pages: 1235-1247
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Publication
11773082 | J:75312
First Author: Kuroda TS
Year: 2002
Journal: J Biol Chem
Title: The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.
Volume: 277
Issue: 11
Pages: 9212-8
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Publication
11056535 | J:71886
First Author: Ozaki N
Year: 2000
Journal: Nat Cell Biol
Title: cAMP-GEFII is a direct target of cAMP in regulated exocytosis.
Volume: 2
Issue: 11
Pages: 805-11
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Publication
11359932 | J:126869
First Author: Tanaka M
Year: 2001
Journal: Mol Biol Cell
Title: Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction.
Volume: 12
Issue: 5
Pages: 1421-30
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Publication
33753311 | J:317639
 
First Author: Bourgeois-Jaarsma Q
Year: 2021
Journal: Mol Cell Neurosci
Title: Ca2+ sensor proteins in spontaneous release and synaptic plasticity: Limited contribution of Doc2c, rabphilin-3a and synaptotagmin 7 in hippocampal glutamatergic neurons.
Volume: 112
Pages: 103613
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Publication
14559211 | J:86115
First Author: Mashimo T
Year: 2003
Journal: Genomics
Title: Structural and functional genomics and evolutionary relationships in the cluster of genes encoding murine 2',5'-oligoadenylate synthetases.
Volume: 82
Issue: 5
Pages: 537-52
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Publication
12578829 | J:83108
First Author: Fukuda M
Year: 2003
Journal: J Biol Chem
Title: Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.
Volume: 278
Issue: 17
Pages: 15373-80
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Publication
12590134 | J:83162
First Author: Fukuda M
Year: 2003
Journal: J Biol Chem
Title: Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.
Volume: 278
Issue: 17
Pages: 15390-6
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Publication
17803915 | J:127941
First Author: Yao I
Year: 2007
Journal: Cell
Title: SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release.
Volume: 130
Issue: 5
Pages: 943-57
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Publication
12080145 | J:77001
First Author: Perelygin AA
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Positional cloning of the murine flavivirus resistance gene.
Volume: 99
Issue: 14
Pages: 9322-7
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Publication
16364898 | J:107595
First Author: Landsberg RL
Year: 2005
Journal: Neuron
Title: Hindbrain rhombic lip is comprised of discrete progenitor cell populations allocated by Pax6.
Volume: 48
Issue: 6
Pages: 933-47
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Publication
31869353 | J:283382
First Author: Qin L
Year: 2019
Journal: PLoS One
Title: Analyses with double knockouts of the Bmpr1a and Bmpr1b genes demonstrate that BMP signaling is involved in the formation of precerebellar mossy fiber nuclei derived from the rhombic lip.
Volume: 14
Issue: 12
Pages: e0226602
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Publication
18987029 | J:143205
First Author: Kanadia RN
Year: 2008
Journal: Development
Title: Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons.
Volume: 135
Issue: 23
Pages: 3923-33
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Publication
18829970 | J:143462
First Author: Liu Z
Year: 2008
Journal: J Neurosci
Title: Control of precerebellar neuron development by Olig3 bHLH transcription factor.
Volume: 28
Issue: 40
Pages: 10124-33
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Publication
17124501 | J:119934
First Author: Schoch S
Year: 2006
Journal: EMBO J
Title: Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.
Volume: 25
Issue: 24
Pages: 5852-63
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Publication
29445148 | J:314661
First Author: Zhang Q
Year: 2018
Journal: Cell Death Dis
Title: Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification.
Volume: 9
Issue: 2
Pages: 247
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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