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Search results 1 to 100 out of 608 for Ryr1

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
6261 | RYR1
Type: gene
Organism: human
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Gene
100495378 | ryr1
Type: gene
Organism: frog, western clawed
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Gene
114207 | Ryr1
Type: gene
Organism: rat
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Gene
606491 | RYR1
Type: gene
Organism: dog, domestic
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Gene
100139857 | RYR1
Type: gene
Organism: cattle
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Gene
100612063 | RYR1
Type: gene
Organism: chimpanzee
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Gene
693612 | RYR1
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR033215 | RyR1
Type: Family
Description: The function of skeletal muscle relies on the movement of Ca2+ out of and back into the storage compartment (SR). Ryanodine receptor 1 (RyR) functions as a Ca2+-release channels, releasing Ca2+ from the SR, resulting in muscle contraction [].Mutations in the RyR1 gene cause malignant hyperthermia 1 (MHS1), an autosomal dominant pharmacogenetic disorder of skeletal muscle and is one of the main causes of death due to anesthesia [, ].
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Protein Coding Gene
MGI:99659 | Ryr1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
26793121 | -
 
First Author: Hernández-Ochoa EO
Year: 2015
Journal: Front Physiol
Title: Critical Role of Intracellular RyR1 Calcium Release Channels in Skeletal Muscle Function and Disease.
Volume: 6
Pages: 420
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Protein
E9PZQ0
Organism: Mus musculus/domesticus
Length: 5035  
Fragment?: false
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GXD Expression
GXD Expression
   
Probe: MGI:6306084
Assay Type: RT-PCR
Annotation Date: 2019-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757720
Stage: TS20
Assay Id: MGI:6306089
Age: embryonic day 12.5
Image: S1
Specimen Label: Ryr1 AG/AG
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6306084
Assay Type: RT-PCR
Annotation Date: 2019-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:6306092
Age: embryonic day 14.5
Image: S1
Specimen Label: Ryr1 AG/AG
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6306084
Assay Type: RT-PCR
Annotation Date: 2019-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:6306095
Age: embryonic day 18.5
Image: S1
Specimen Label: Ryr1 AG/AG
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6306084
Assay Type: RT-PCR
Annotation Date: 2019-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:6306102
Age: embryonic day 18.5
Image: 6
Specimen Label: Ryr1 AG/AG
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6306084
Assay Type: RT-PCR
Annotation Date: 2019-05-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:6306102
Age: embryonic day 18.5
Image: 6
Specimen Label: Ryr1 -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6306084
Assay Type: RT-PCR
Annotation Date: 2019-05-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:6306098
Age: embryonic day 14.5
Image: S1
Specimen Label: Ryr1 -/-
Detected: false
Specimen Num: 2
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Publication
28337975 | J:244199
 
First Author: Lee CS
Year: 2017
Journal: Nat Commun
Title: A chemical chaperone improves muscle function in mice with a RyR1 mutation.
Volume: 8
Pages: 14659
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Protein
Q99JF3
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: true
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Publication
1354642 | -
First Author: Gillard EF
Year: 1992
Journal: Genomics
Title: Polymorphisms and deduced amino acid substitutions in the coding sequence of the ryanodine receptor (RYR1) gene in individuals with malignant hyperthermia.
Volume: 13
Issue: 4
Pages: 1247-54
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Publication
1774074 | -
First Author: Gillard EF
Year: 1991
Journal: Genomics
Title: A substitution of cysteine for arginine 614 in the ryanodine receptor is potentially causative of human malignant hyperthermia.
Volume: 11
Issue: 3
Pages: 751-5
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Publication
16284304 | J:105738
First Author: Chelu MG
Year: 2006
Journal: FASEB J
Title: Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse.
Volume: 20
Issue: 2
Pages: 329-30
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Publication
33176865 | J:312214
First Author: Pelletier L
Year: 2020
Journal: Acta Neuropathol Commun
Title: In vivo RyR1 reduction in muscle triggers a core-like myopathy.
Volume: 8
Issue: 1
Pages: 192
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Publication
18394989 | J:136130
First Author: Durham WJ
Year: 2008
Journal: Cell
Title: RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knockin mice.
Volume: 133
Issue: 1
Pages: 53-65
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Publication
38203604 | J:344242
 
First Author: Thekkedam CG
Year: 2023
Journal: Int J Mol Sci
Title: The RyR1 P3528S Substitution Alters Mouse Skeletal Muscle Contractile Properties and RyR1 Ion Channel Gating.
Volume: 25
Issue: 1
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Protein
K3W4M2
Organism: Mus musculus/domesticus
Length: 5033  
Fragment?: false
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Protein
A0A1L1SQG7
Organism: Mus musculus/domesticus
Length: 5061  
Fragment?: false
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Publication
12704193 | J:84111
First Author: Avila G
Year: 2003
Journal: J Biol Chem
Title: FKBP12 binding to RyR1 modulates excitation-contraction coupling in mouse skeletal myotubes.
Volume: 278
Issue: 25
Pages: 22600-8
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Publication
17122579 | J:168222
First Author: Yang T
Year: 2006
Journal: Anesthesiology
Title: Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse.
Volume: 105
Issue: 6
Pages: 1164-75
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Publication
32506037 | J:312808
 
First Author: Cully TR
Year: 2020
Journal: Redox Biol
Title: Nox4 - RyR1 - Nox2: Regulators of micro-domain signaling in skeletal muscle.
Volume: 36
Pages: 101557
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Publication
33037202 | J:298094
First Author: Wang HJ
Year: 2020
Journal: Nat Commun
Title: Adaptive thermogenesis enhances the life-threatening response to heat in mice with an Ryr1 mutation.
Volume: 11
Issue: 1
Pages: 5099
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Publication
27382027 | J:259535
First Author: Lopez RJ
Year: 2016
Journal: Sci Signal
Title: An RYR1 mutation associated with malignant hyperthermia is also associated with bleeding abnormalities.
Volume: 9
Issue: 435
Pages: ra68
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Publication
22853897 | J:327848
First Author: Yarotskyy V
Year: 2012
Journal: Biophys J
Title: Temperature and RyR1 regulate the activation rate of store-operated Ca²+ entry current in myotubes.
Volume: 103
Issue: 2
Pages: 202-11
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Publication
22231556 | J:181209
First Author: Lanner JT
Year: 2012
Journal: Nat Med
Title: AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation.
Volume: 18
Issue: 2
Pages: 244-51
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Publication
20479108 | J:168221
First Author: Bannister RA
Year: 2010
Journal: J Gen Physiol
Title: A malignant hyperthermia-inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels.
Volume: 135
Issue: 6
Pages: 629-40
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Publication
31044239 | J:292405
First Author: Elbaz M
Year: 2019
Journal: Hum Mol Genet
Title: Quantitative RyR1 reduction and loss of calcium sensitivity of RyR1Q1970fsX16+A4329D cause cores and loss of muscle strength.
Volume: 28
Issue: 18
Pages: 2987-2999
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Publication
20479110 | J:168220
First Author: Estève E
Year: 2010
Journal: J Gen Physiol
Title: A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR.
Volume: 135
Issue: 6
Pages: 619-28
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Publication
30689883 | J:275501
First Author: Elbaz M
Year: 2019
Journal: Hum Mol Genet
Title: Quantitative reduction of RyR1 protein caused by a single-allele frameshift mutation in RYR1 ex36 impairs the strength of adult skeletal muscle fibres.
Volume: 28
Issue: 11
Pages: 1872-1884
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Publication
19246389 | J:146776
First Author: Andronache Z
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: A retrograde signal from RyR1 alters DHP receptor inactivation and limits window Ca2+ release in muscle fibers of Y522S RyR1 knock-in mice.
Volume: 106
Issue: 11
Pages: 4531-6
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Publication
29543863 | J:260112
First Author: Filipova D
Year: 2018
Journal: PLoS One
Title: Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5.
Volume: 13
Issue: 3
Pages: e0194428
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Publication
37468098 | J:339705
First Author: Zhang IX
Year: 2023
Journal: J Biol Chem
Title: ER stress increases expression of intracellular calcium channel RyR1 to modify Ca(2+) homeostasis in pancreatic beta cells.
Volume: 299
Issue: 8
Pages: 105065
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Publication
30563862 | J:284476
 
First Author: Diercks BP
Year: 2018
Journal: Sci Signal
Title: ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.
Volume: 11
Issue: 561
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Publication
32242214 | J:291685
First Author: Eckhardt J
Year: 2020
Journal: Hum Mol Genet
Title: Molecular basis of impaired extraocular muscle function in a mouse model of congenital myopathy due to compound heterozygous Ryr1 mutations.
Volume: 29
Issue: 8
Pages: 1330-1339
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Publication
12376096 | J:79494
First Author: Martins-Wess F
Year: 2002
Journal: Genomics
Title: Construction of a 1.2-Mb BAC/PAC contig of the porcine gene RYR1 region on SSC 6q1.2 and comparative analysis with HSA 19q13.13.
Volume: 80
Issue: 4
Pages: 416-22
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Publication
12954602 | J:87930
First Author: Shtifman A
Year: 2004
Journal: Am J Physiol Cell Physiol
Title: Ca2+ influx through alpha1S DHPR may play a role in regulating Ca2+ release from RyR1 in skeletal muscle.
Volume: 286
Issue: 1
Pages: C73-8
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Publication
32826313 | J:300593
First Author: Chang L
Year: 2020
Journal: J Biol Chem
Title: Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia.
Volume: 295
Issue: 45
Pages: 15226-15235
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Publication
25564733 | J:219285
   
First Author: Hanson MG
Year: 2015
Journal: Elife
Title: Potassium dependent rescue of a myopathy with core-like structures in mouse.
Volume: 4
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Publication
32693782 | J:328160
First Author: Nogami K
Year: 2020
Journal: BMC Musculoskelet Disord
Title: iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin.
Volume: 21
Issue: 1
Pages: 479
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Publication
36450915 | J:331968
First Author: Germani S
Year: 2022
Journal: Sci Rep
Title: Loss-of-rescue of Ryr1(I4895T)-related pathology by the genetic inhibition of the ER stress response mediator CHOP.
Volume: 12
Issue: 1
Pages: 20632
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Publication
26025922 | J:224393
First Author: Gartz Hanson M
Year: 2015
Journal: Dev Biol
Title: Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.
Volume: 404
Issue: 2
Pages: 76-87
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Publication
34257294 | J:322211
First Author: Yamazawa T
Year: 2021
Journal: Nat Commun
Title: A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke.
Volume: 12
Issue: 1
Pages: 4293
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Publication
23070698 | J:205099
First Author: Andersson DC
Year: 2012
Journal: J Physiol
Title: Stress-induced increase in skeletal muscle force requires protein kinase A phosphorylation of the ryanodine receptor.
Volume: 590
Issue: 24
Pages: 6381-7
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Publication
22036948 | J:180237
First Author: Kakizawa S
Year: 2012
Journal: EMBO J
Title: Nitric oxide-induced calcium release via ryanodine receptors regulates neuronal function.
Volume: 31
Issue: 2
Pages: 417-28
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Publication
18650434 | J:142324
First Author: Wright NT
Year: 2008
Journal: J Biol Chem
Title: S100A1 and calmodulin compete for the same binding site on ryanodine receptor.
Volume: 283
Issue: 39
Pages: 26676-83
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Publication
9489997 | J:45803
First Author: Barone V
Year: 1998
Journal: FEBS Lett
Title: Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.
Volume: 422
Issue: 2
Pages: 160-4
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Publication
21803290 | J:176731
First Author: Andersson DC
Year: 2011
Journal: Cell Metab
Title: Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging.
Volume: 14
Issue: 2
Pages: 196-207
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Publication
18003898 | J:127629
First Author: Zvaritch E
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: An Ryr1I4895T mutation abolishes Ca2+ release channel function and delays development in homozygous offspring of a mutant mouse line.
Volume: 104
Issue: 47
Pages: 18537-42
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Publication
19959667 | J:155825
First Author: Zvaritch E
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Ca2+ dysregulation in Ryr1(I4895T/wt) mice causes congenital myopathy with progressive formation of minicores, cores, and nemaline rods.
Volume: 106
Issue: 51
Pages: 21813-8
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Publication
31107960 | J:275500
     
First Author: Brennan S
Year: 2019
Journal: Hum Mol Genet
Title: Mouse model of severe recessive RYR1-related myopathy.
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Publication
19966218 | J:155819
First Author: Boncompagni S
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Characterization and temporal development of cores in a mouse model of malignant hyperthermia.
Volume: 106
Issue: 51
Pages: 21996-2001
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Publication
29701772 | J:265105
First Author: Suman M
Year: 2018
Journal: Hum Mol Genet
Title: Inositol trisphosphate receptor-mediated Ca2+ signalling stimulates mitochondrial function and gene expression in core myopathy patients.
Volume: 27
Issue: 13
Pages: 2367-2382
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Publication
22203976 | J:179979
First Author: De Crescenzo V
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Type 1 ryanodine receptor knock-in mutation causing central core disease of skeletal muscle also displays a neuronal phenotype.
Volume: 109
Issue: 2
Pages: 610-5
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Publication
17925380 | J:128454
First Author: Fritz N
Year: 2007
Journal: J Cell Sci
Title: RyR1-specific requirement for depolarization-induced Ca2+ sparks in urinary bladder smooth muscle.
Volume: 120
Issue: Pt 21
Pages: 3784-91
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Publication
20978128 | J:168219
First Author: Giulivi C
Year: 2011
Journal: J Biol Chem
Title: Basal bioenergetic abnormalities in skeletal muscle from ryanodine receptor malignant hyperthermia-susceptible R163C knock-in mice.
Volume: 286
Issue: 1
Pages: 99-113
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Publication
23159934 | J:196987
First Author: Eltit JM
Year: 2013
Journal: FASEB J
Title: Nonspecific sarcolemmal cation channels are critical for the pathogenesis of malignant hyperthermia.
Volume: 27
Issue: 3
Pages: 991-1000
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Publication
37591734 | J:340582
 
First Author: Osman V
Year: 2023
Journal: eNeuro
Title: Isoflurane Alters Presynaptic Endoplasmic Reticulum Calcium Dynamics in Wild-Type and Malignant Hyperthermia-Susceptible Rodent Hippocampal Neurons.
Volume: 10
Issue: 8
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Publication
37670077 | J:340573
First Author: Magyar ZÉ
Year: 2023
Journal: Sci Rep
Title: Function of a mutant ryanodine receptor (T4709M) linked to congenital myopathy.
Volume: 13
Issue: 1
Pages: 14659
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Publication
35238775 | J:328692
   
First Author: Ruiz A
Year: 2022
Journal: Elife
Title: Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors.
Volume: 11
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Publication
8618963 | J:32590
First Author: Mickelson JR
Year: 1996
Journal: Physiol Rev
Title: Malignant hyperthermia: excitation-contraction coupling, Ca2+ release channel, and cell Ca2+ regulation defects.
Volume: 76
Issue: 2
Pages: 537-92
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Publication
12642598 | J:82858
First Author: Avila G
Year: 2003
Journal: J Gen Physiol
Title: The pore region of the skeletal muscle ryanodine receptor is a primary locus for excitation-contraction uncoupling in central core disease.
Volume: 121
Issue: 4
Pages: 277-86
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Publication
16246297 | J:104052
First Author: Beutner G
Year: 2005
Journal: Biochim Biophys Acta
Title: Type 1 ryanodine receptor in cardiac mitochondria: transducer of excitation-metabolism coupling.
Volume: 1717
Issue: 1
Pages: 1-10
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Publication
22505613 | J:197779
First Author: Fourest-Lieuvin A
Year: 2012
Journal: J Cell Sci
Title: Role of triadin in the organization of reticulum membrane at the muscle triad.
Volume: 125
Issue: Pt 14
Pages: 3443-53
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Publication
18268335 | J:132211
First Author: Bellinger AM
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity.
Volume: 105
Issue: 6
Pages: 2198-202
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Publication
21896730 | J:176588
First Author: Sun QA
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4.
Volume: 108
Issue: 38
Pages: 16098-103
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Publication
23223241 | J:328062
First Author: Tjondrokoesoemo A
Year: 2013
Journal: J Biol Chem
Title: Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.
Volume: 288
Issue: 4
Pages: 2103-9
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Publication
10788707 | J:63370
First Author: Mori F
Year: 2000
Journal: Neurosci Lett
Title: Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.
Volume: 285
Issue: 1
Pages: 57-60
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Publication
11500519 | J:72345
First Author: Yang D
Year: 2001
Journal: J Biol Chem
Title: RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle.
Volume: 276
Issue: 43
Pages: 40210-4
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Publication
27621462 | J:238343
First Author: Polster A
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Stac3 has a direct role in skeletal muscle-type excitation-contraction coupling that is disrupted by a myopathy-causing mutation.
Volume: 113
Issue: 39
Pages: 10986-91
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Publication
9799464 | J:113063
First Author: Komazaki S
Year: 1998
Journal: Cell Tissue Res
Title: Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.
Volume: 294
Issue: 3
Pages: 467-73
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Publication
36010545 | J:327913
 
First Author: Serano M
Year: 2022
Journal: Cells
Title: Oxygen Consumption and Basal Metabolic Rate as Markers of Susceptibility to Malignant Hyperthermia and Heat Stroke.
Volume: 11
Issue: 16
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Publication
21156754 | J:168218
First Author: Feng W
Year: 2011
Journal: Mol Pharmacol
Title: Functional and biochemical properties of ryanodine receptor type 1 channels from heterozygous R163C malignant hyperthermia-susceptible mice.
Volume: 79
Issue: 3
Pages: 420-31
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Publication
22139840 | J:181523
First Author: Barrientos GC
Year: 2012
Journal: J Biol Chem
Title: Gene dose influences cellular and calcium channel dysregulation in heterozygous and homozygous T4826I-RYR1 malignant hyperthermia-susceptible muscle.
Volume: 287
Issue: 4
Pages: 2863-76
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Publication
21969454 | J:191545
First Author: Lefebvre R
Year: 2011
Journal: J Physiol
Title: Defects in Ca2+ release associated with local expression of pathological ryanodine receptors in mouse muscle fibres.
Volume: 589
Issue: Pt 22
Pages: 5361-82
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Publication
15289441 | J:94747
First Author: Tang W
Year: 2004
Journal: FASEB J
Title: Altered excitation-contraction coupling with skeletal muscle specific FKBP12 deficiency.
Volume: 18
Issue: 13
Pages: 1597-9
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Publication
21289290 | J:195542
First Author: Yamaguchi N
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1.
Volume: 300
Issue: 5
Pages: C998-C1012
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Publication
21933672 | J:189480
First Author: Huang W
Year: 2011
Journal: Exp Eye Res
Title: Localization and phenotype-specific expression of ryanodine calcium release channels in C57BL6 and DBA/2J mouse strains.
Volume: 93
Issue: 5
Pages: 700-9
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Publication
10736313 | J:106295
First Author: Avila G
Year: 2000
Journal: J Gen Physiol
Title: Functional impact of the ryanodine receptor on the skeletal muscle L-type Ca(2+) channel.
Volume: 115
Issue: 4
Pages: 467-80
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Publication
7876312 | J:23314
First Author: Giannini G
Year: 1995
Journal: J Cell Biol
Title: The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.
Volume: 128
Issue: 5
Pages: 893-904
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Publication
18313230 | J:135635
First Author: Sawada K
Year: 2008
Journal: Neuroscience
Title: Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya.
Volume: 152
Issue: 3
Pages: 609-17
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Publication
19198614 | J:146474
First Author: Bellinger AM
Year: 2009
Journal: Nat Med
Title: Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle.
Volume: 15
Issue: 3
Pages: 325-30
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Publication
11159936 | J:67173
First Author: Tiso N
Year: 2001
Journal: Hum Mol Genet
Title: Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).
Volume: 10
Issue: 3
Pages: 189-94
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Publication
15972723 | J:100392
First Author: Kimura T
Year: 2005
Journal: Hum Mol Genet
Title: Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1.
Volume: 14
Issue: 15
Pages: 2189-200
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Publication
30236258 | J:303297
First Author: Lopez JR
Year: 2018
Journal: Br J Anaesth
Title: Malignant hyperthermia, environmental heat stress, and intracellular calcium dysregulation in a mouse model expressing the p.G2435R variant of RYR1.
Volume: 121
Issue: 4
Pages: 953-961
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Publication
22131268 | J:181904
First Author: Yuen B
Year: 2012
Journal: FASEB J
Title: Mice expressing T4826I-RYR1 are viable but exhibit sex- and genotype-dependent susceptibility to malignant hyperthermia and muscle damage.
Volume: 26
Issue: 3
Pages: 1311-22
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Publication
16844763 | J:112566
First Author: Stolk M
Year: 2006
Journal: J Leukoc Biol
Title: IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.
Volume: 80
Issue: 3
Pages: 651-8
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Publication
10444070 | J:56913
First Author: Flucher BE
Year: 1999
Journal: J Cell Biol
Title: Type 3 and type 1 ryanodine receptors are localized in triads of the same mammalian skeletal muscle fibers.
Volume: 146
Issue: 3
Pages: 621-30
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Publication
30870432 | J:273796
First Author: Liu Y
Year: 2019
Journal: PLoS Genet
Title: Blocking skeletal muscle DHPRs/Ryr1 prevents neuromuscular synapse loss in mutant mice deficient in type III Neuregulin 1 (CRD-Nrg1).
Volume: 15
Issue: 3
Pages: e1007857
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Publication
26831464 | J:356935
 
First Author: Filipova D
Year: 2016
Journal: Sci Rep
Title: Gene profiling of embryonic skeletal muscle lacking type I ryanodine receptor Ca(2+) release channel.
Volume: 6
Pages: 20050
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Publication
9124414 | J:38828
First Author: Marks AR
Year: 1997
Journal: Am J Physiol
Title: Intracellular calcium-release channels: regulators of cell life and death.
Volume: 272
Issue: 2 Pt 2
Pages: H597-605
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Protein Coding Gene
MGP_CAROLIEiJ_G0029471 | -
Type: protein_coding_gene
Organism: Mus caroli
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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