| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Endophilin-B1 is a BAR and SH3 (Src homology 3) domain-containing protein and a member of the endophilin family that is localised predominantly to intracellular membranes. It regulates the membrane dynamics of various intracellular compartments such as mitochondria and autophagosome formation in fibroblast [, ]. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takahashi Y |
| Year: |
2011 |
| Journal: |
Autophagy |
| Title: |
Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy. |
| Volume: |
7 |
| Issue: |
1 |
| Pages: |
61-73 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
365
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
194
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
394
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
140
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cheung ZH |
| Year: |
2009 |
| Journal: |
Commun Integr Biol |
| Title: |
Endophilin B1: Guarding the gate to destruction. |
| Volume: |
2 |
| Issue: |
2 |
| Pages: |
130-2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Khan MM |
| Year: |
2014 |
| Journal: |
Autophagy |
| Title: |
Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
123-36 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang DB |
| Year: |
2014 |
| Journal: |
J Neurosci |
| Title: |
Bax interacting factor-1 promotes survival and mitochondrial elongation in neurons. |
| Volume: |
34 |
| Issue: |
7 |
| Pages: |
2674-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang DB |
| Year: |
2015 |
| Journal: |
Brain |
| Title: |
Loss of endophilin-B1 exacerbates Alzheimer's disease pathology. |
| Volume: |
138 |
| Issue: |
Pt 7 |
| Pages: |
2005-19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu Y |
| Year: |
2016 |
| Journal: |
Sci Rep |
| Title: |
Bif-1 deficiency impairs lipid homeostasis and causes obesity accompanied by insulin resistance. |
| Volume: |
6 |
|
| Pages: |
20453 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Touyama K |
| Year: |
2019 |
| Journal: |
J Cell Biochem |
| Title: |
Bif-1/Endophilin B1/SH3GLB1 regulates bone homeostasis. |
| Volume: |
120 |
| Issue: |
11 |
| Pages: |
18793-18804 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cuddeback SM |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax. |
| Volume: |
276 |
| Issue: |
23 |
| Pages: |
20559-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Farsad K |
| Year: |
2001 |
| Journal: |
J Cell Biol |
| Title: |
Generation of high curvature membranes mediated by direct endophilin bilayer interactions. |
| Volume: |
155 |
| Issue: |
2 |
| Pages: |
193-200 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3800310 |
| Assay Type: |
Western blot |
| Annotation Date: |
2008-08-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603920 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:3800330 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
Bif-1 +/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3800310 |
| Assay Type: |
Western blot |
| Annotation Date: |
2008-08-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603920 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:3800330 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
Bif-1 +/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3800310 |
| Assay Type: |
Western blot |
| Annotation Date: |
2008-08-05 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603920 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:3800330 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
Bif-1 -/- |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5640731 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2015-06-17 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3647224 |
|
| Stage: |
TS24 |
| Assay Id: |
MGI:5640803 |
| Age: |
embryonic day 16.5 |
| Image: |
S5 |
|
| Specimen Label: |
bv/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5640731 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2015-06-17 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3647224 |
|
| Stage: |
TS24 |
| Assay Id: |
MGI:5640803 |
| Age: |
embryonic day 16.5 |
| Image: |
S5 |
|
| Specimen Label: |
bv/bv |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5640731 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2015-06-17 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1778728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5640865 |
| Age: |
postnatal day 15 |
| Image: |
S5 |
|
| Specimen Label: |
ce |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5640731 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2015-06-17 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5640865 |
| Age: |
postnatal day 15 |
| Image: |
S5 |
|
| Specimen Label: |
sp |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5640731 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2015-06-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1778728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5641080 |
| Age: |
postnatal day 15 |
| Image: |
S7 |
|
| Specimen Label: |
bv/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5640731 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2015-06-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1778728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5641080 |
| Age: |
postnatal day 15 |
| Image: |
S7 |
|
| Specimen Label: |
bv/bv |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543004 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-10-24 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284226 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:7543246 |
| Age: |
embryonic day 19.0 |
| Image: |
S4 |
|
| Specimen Label: |
WT |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543004 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-10-24 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284226 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:7543246 |
| Age: |
embryonic day 19.0 |
| Image: |
S4 |
|
| Specimen Label: |
dMut |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7661083 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-07-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754422 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:7662267 |
| Age: |
embryonic day 14.0 |
|
|
| Specimen Label: |
E14 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7661083 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-07-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754424 |
|
| Stage: |
TS24 |
| Assay Id: |
MGI:7662267 |
| Age: |
embryonic day 16.0 |
|
|
| Specimen Label: |
E16 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7661083 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-07-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754426 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:7662267 |
| Age: |
embryonic day 18.0 |
|
|
| Specimen Label: |
E18 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7661083 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-07-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754427 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:7662267 |
| Age: |
postnatal day 0 |
|
|
| Specimen Label: |
P0 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7661083 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-07-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7662267 |
| Age: |
postnatal day 7 |
|
|
| Specimen Label: |
P7 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7661083 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-07-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7662267 |
| Age: |
postnatal day 21 |
|
|
| Specimen Label: |
P21 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7661083 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-07-02 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7662267 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Adult |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3505902 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2004-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1666917 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:3510331 |
| Age: |
embryonic day 10.5 |
| Image: |
2L |
| Note: |
Otic vesicle; dorsally restricted expression. |
| Specimen Label: |
2L |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3505902 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2004-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1699417 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:3510331 |
| Age: |
embryonic day 10.5 |
| Image: |
2L |
| Note: |
Endolymphatic duct. |
| Specimen Label: |
2L |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Modregger J |
| Year: |
2000 |
| Journal: |
GenBank Submission |
| Title: |
Mus musculus endophilin B1a mRNA, complete cds, alternatively spliced |
|
|
| Pages: |
AF263364 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hrabchak C |
| Year: |
2007 |
| Journal: |
Biochemistry |
| Title: |
A testis specific isoform of endophilin B1, endophilin B1t, interacts specifically with protein phosphatase-1c gamma2 in mouse testis and is abnormally expressed in PP1c gamma null mice. |
| Volume: |
46 |
| Issue: |
15 |
| Pages: |
4635-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takahashi Y |
| Year: |
2013 |
| Journal: |
Blood |
| Title: |
Bif-1 haploinsufficiency promotes chromosomal instability and accelerates Myc-driven lymphomagenesis via suppression of mitophagy. |
| Volume: |
121 |
| Issue: |
9 |
| Pages: |
1622-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wong AS |
| Year: |
2011 |
| Journal: |
Nat Cell Biol |
| Title: |
Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease. |
| Volume: |
13 |
| Issue: |
5 |
| Pages: |
568-79 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Maiuri MC |
| Year: |
2009 |
| Journal: |
Cell Death Differ |
| Title: |
Control of autophagy by oncogenes and tumor suppressor genes. |
| Volume: |
16 |
| Issue: |
1 |
| Pages: |
87-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takahashi Y |
| Year: |
2007 |
| Journal: |
Nat Cell Biol |
| Title: |
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. |
| Volume: |
9 |
| Issue: |
10 |
| Pages: |
1142-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wheeler FC |
| Year: |
2005 |
| Journal: |
Mamm Genome |
| Title: |
QTL mapping in a mouse model of cardiomyopathy reveals an ancestral modifier allele affecting heart function and survival. |
| Volume: |
16 |
| Issue: |
6 |
| Pages: |
414-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang Y |
| Year: |
2015 |
| Journal: |
Cell Res |
| Title: |
Endophilin A1 regulates dendritic spine morphogenesis and stability through interaction with p140Cap. |
| Volume: |
25 |
| Issue: |
4 |
| Pages: |
496-516 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takahashi Y |
| Year: |
2005 |
| Journal: |
Mol Cell Biol |
| Title: |
Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis. |
| Volume: |
25 |
| Issue: |
21 |
| Pages: |
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