| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
Not Specified |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
SIX1 is a transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development []. It plays important roles in organogenesis and tumorigenesis []. |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Coletta RD |
| Year: |
2004 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1. |
| Volume: |
101 |
| Issue: |
17 |
| Pages: |
6478-83 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
284
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu W |
| Year: |
2015 |
| Journal: |
Int J Cancer |
| Title: |
Six1: a critical transcription factor in tumorigenesis. |
| Volume: |
136 |
| Issue: |
6 |
| Pages: |
1245-53 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4833957 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760617 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:6378182 |
| Age: |
embryonic day 10.5 |
| Image: |
8A Six1 |
|
| Specimen Label: |
8A Six1 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4833957 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760617 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:6378182 |
| Age: |
embryonic day 10.5 |
| Image: |
8B Six1 |
|
| Specimen Label: |
8B Six1 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4833957 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760617 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:6378182 |
| Age: |
embryonic day 10.5 |
| Image: |
8C Six1 |
|
| Specimen Label: |
8C Six1 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4833957 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760617 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:6378182 |
| Age: |
embryonic day 10.5 |
| Image: |
8D Six1 |
|
| Specimen Label: |
8D Six1 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4833957 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760617 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:6378182 |
| Age: |
embryonic day 10.5 |
| Image: |
8E Six1 |
|
| Specimen Label: |
8E Six1 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4833957 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760617 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:6378182 |
| Age: |
embryonic day 10.5 |
| Image: |
8F Six1 |
|
| Specimen Label: |
8F Six1 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7328409 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-31 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3585028 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7486071 |
| Age: |
postnatal adult |
| Image: |
8E Six1 LacZ/+ |
| Note: |
Expression in Type II taste receptors. |
| Specimen Label: |
8E Six1 LacZ/+ |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4833957 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1654315 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:6378182 |
| Age: |
embryonic day 9.5 |
| Image: |
3B WT Six1 |
|
| Specimen Label: |
3B WT Six1 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4833957 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760617 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:6378182 |
| Age: |
embryonic day 10.5 |
| Image: |
9C Six1 E10.5 |
|
| Specimen Label: |
9C Six1 E10.5 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4833957 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760619 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:6378182 |
| Age: |
embryonic day 11.5 |
| Image: |
9C Six1 E11.5 |
|
| Specimen Label: |
9C Six1 E11.5 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7328409 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-31 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3585028 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:7486071 |
| Age: |
postnatal adult |
| Image: |
8E Six1 LacZ/LacZ |
| Note: |
Number of Type II taste receptors reduced compared to wild type. |
| Specimen Label: |
8E Six1 LacZ/LacZ |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4833957 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-11-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1654315 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:6378182 |
| Age: |
embryonic day 9.5 |
| Image: |
3A WT Six1 |
|
| Specimen Label: |
3A WT Six1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4833952 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2001-08-28 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603917 |
|
| Stage: |
TS17 |
| Assay Id: |
MGI:2148792 |
| Age: |
embryonic day 10.5 |
|
|
| Specimen Label: |
Six1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu PX |
| Year: |
2003 |
| Journal: |
Development |
| Title: |
Six1 is required for the early organogenesis of mammalian kidney. |
| Volume: |
130 |
| Issue: |
14 |
| Pages: |
3085-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ruf RG |
| Year: |
2004 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes. |
| Volume: |
101 |
| Issue: |
21 |
| Pages: |
8090-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ozaki H |
| Year: |
2004 |
| Journal: |
Development |
| Title: |
Six1 controls patterning of the mouse otic vesicle. |
| Volume: |
131 |
| Issue: |
3 |
| Pages: |
551-62 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
284
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
284
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Richard AF |
| Year: |
2011 |
| Journal: |
Dev Biol |
| Title: |
Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. |
| Volume: |
359 |
| Issue: |
2 |
| Pages: |
303-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Laclef C |
| Year: |
2003 |
| Journal: |
Mech Dev |
| Title: |
Thymus, kidney and craniofacial abnormalities in Six 1 deficient mice. |
| Volume: |
120 |
| Issue: |
6 |
| Pages: |
669-79 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sato S |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
Activation of Six1 Expression in Vertebrate Sensory Neurons. |
| Volume: |
10 |
| Issue: |
8 |
| Pages: |
e0136666 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Luo S |
| Year: |
2023 |
| Journal: |
Front Genet |
| Title: |
Ectomesenchymal Six1 controls mandibular skeleton formation. |
| Volume: |
14 |
|
| Pages: |
1082911 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sato S |
| Year: |
2012 |
| Journal: |
Dev Biol |
| Title: |
Regulation of Six1 expression by evolutionarily conserved enhancers in tetrapods. |
| Volume: |
368 |
| Issue: |
1 |
| Pages: |
95-108 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Spitz F |
| Year: |
1998 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site. |
| Volume: |
95 |
| Issue: |
24 |
| Pages: |
14220-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Laclef C |
| Year: |
2003 |
| Journal: |
Development |
| Title: |
Altered myogenesis in Six1-deficient mice. |
| Volume: |
130 |
| Issue: |
10 |
| Pages: |
2239-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sato S |
| Year: |
2018 |
| Journal: |
Dev Dyn |
| Title: |
Regulation of continuous but complex expression pattern of Six1 during early sensory development. |
| Volume: |
247 |
| Issue: |
1 |
| Pages: |
250-261 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu Y |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
Six1 regulates MyoD expression in adult muscle progenitor cells. |
| Volume: |
8 |
| Issue: |
6 |
| Pages: |
e67762 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zheng W |
| Year: |
2003 |
| Journal: |
Development |
| Title: |
The role of Six1 in mammalian auditory system development. |
| Volume: |
130 |
| Issue: |
17 |
| Pages: |
3989-4000 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nie X |
| Year: |
2010 |
| Journal: |
Development |
| Title: |
SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation. |
| Volume: |
137 |
| Issue: |
5 |
| Pages: |
755-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu J |
| Year: |
2022 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Six1 and Six2 of the Sine Oculis Homeobox Subfamily are Not Functionally Interchangeable in Mouse Nephron Formation. |
| Volume: |
10 |
|
| Pages: |
815249 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suzuki Y |
| Year: |
2010 |
| Journal: |
Cell Tissue Res |
| Title: |
Regulatory role of Six1 in the development of taste papillae. |
| Volume: |
339 |
| Issue: |
3 |
| Pages: |
513-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suzuki Y |
| Year: |
2010 |
| Journal: |
J Mol Histol |
| Title: |
Expression of Six1 and Six4 in mouse taste buds. |
| Volume: |
41 |
| Issue: |
4-5 |
| Pages: |
205-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sato S |
| Year: |
2010 |
| Journal: |
Dev Biol |
| Title: |
Conserved expression of mouse Six1 in the pre-placodal region (PPR) and identification of an enhancer for the rostral PPR. |
| Volume: |
344 |
| Issue: |
1 |
| Pages: |
158-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sakakibara I |
| Year: |
2016 |
| Journal: |
Skelet Muscle |
| Title: |
Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle. |
| Volume: |
6 |
| Issue: |
1 |
| Pages: |
30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Boucher CA |
| Year: |
1996 |
| Journal: |
Genomics |
| Title: |
Cloning of the human SIX1 gene and its assignment to chromosome 14. |
| Volume: |
33 |
| Issue: |
1 |
| Pages: |
140-2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang H |
| Year: |
2009 |
| Journal: |
J Biol Chem |
| Title: |
Ski regulates muscle terminal differentiation by transcriptional activation of Myog in a complex with Six1 and Eya3. |
| Volume: |
284 |
| Issue: |
5 |
| Pages: |
2867-79 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu Z |
| Year: |
2019 |
| Journal: |
J Dent Res |
| Title: |
Crucial and Overlapping Roles of Six1 and Six2 in Craniofacial Development. |
| Volume: |
98 |
| Issue: |
5 |
| Pages: |
572-579 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hsu JY |
| Year: |
2022 |
| Journal: |
Cell Rep |
| Title: |
SIX1 reprograms myogenic transcription factors to maintain the rhabdomyosarcoma undifferentiated state. |
| Volume: |
38 |
| Issue: |
5 |
| Pages: |
110323 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang C |
| Year: |
2011 |
| Journal: |
Dev Biol |
| Title: |
Six1 and Eya1 are critical regulators of peri-cloacal mesenchymal progenitors during genitourinary tract development. |
| Volume: |
360 |
| Issue: |
1 |
| Pages: |
186-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Santolini M |
| Year: |
2016 |
| Journal: |
Nucleic Acids Res |
| Title: |
MyoD reprogramming requires Six1 and Six4 homeoproteins: genome-wide cis-regulatory module analysis. |
| Volume: |
44 |
| Issue: |
18 |
| Pages: |
8621-8640 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Konishi Y |
| Year: |
2006 |
| Journal: |
Brain Res |
| Title: |
Six1 and Six4 promote survival of sensory neurons during early trigeminal gangliogenesis. |
| Volume: |
1116 |
| Issue: |
1 |
| Pages: |
93-102 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fujimoto Y |
| Year: |
2013 |
| Journal: |
Dev Cell |
| Title: |
Homeoproteins Six1 and Six4 regulate male sex determination and mouse gonadal development. |
| Volume: |
26 |
| Issue: |
4 |
| Pages: |
416-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suzuki Y |
| Year: |
2011 |
| Journal: |
J Anat |
| Title: |
Development of gustatory papillae in the absence of Six1 and Six4. |
| Volume: |
219 |
| Issue: |
6 |
| Pages: |
710-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tavares ALP |
| Year: |
2017 |
| Journal: |
Development |
| Title: |
Negative regulation of endothelin signaling by SIX1 is required for proper maxillary development. |
| Volume: |
144 |
| Issue: |
11 |
| Pages: |
2021-2031 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wurmser M |
| Year: |
2020 |
| Journal: |
Development |
| Title: |
SIX1 and SIX4 homeoproteins regulate PAX7+ progenitor cell properties during fetal epaxial myogenesis. |
| Volume: |
147 |
| Issue: |
19 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ikeda K |
| Year: |
2007 |
| Journal: |
Dev Biol |
| Title: |
Six1 is essential for early neurogenesis in the development of olfactory epithelium. |
| Volume: |
311 |
| Issue: |
1 |
| Pages: |
53-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nie X |
| Year: |
2011 |
| Journal: |
Dev Biol |
| Title: |
Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis. |
| Volume: |
352 |
| Issue: |
1 |
| Pages: |
141-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang CA |
| Year: |
2012 |
| Journal: |
J Clin Invest |
| Title: |
SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer. |
| Volume: |
122 |
| Issue: |
5 |
| Pages: |
1895-906 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu Y |
| Year: |
2012 |
| Journal: |
Nucleic Acids Res |
| Title: |
Discovery, optimization and validation of an optimal DNA-binding sequence for the Six1 homeodomain transcription factor. |
| Volume: |
40 |
| Issue: |
17 |
| Pages: |
8227-39 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Coletta RD |
| Year: |
2010 |
| Journal: |
BMC Dev Biol |
| Title: |
Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis. |
| Volume: |
10 |
|
| Pages: |
4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawasaki T |
| Year: |
2016 |
| Journal: |
Dev Growth Differ |
| Title: |
Six1 is required for mouse dental follicle cell and human periodontal ligament-derived cell proliferation. |
| Volume: |
58 |
| Issue: |
6 |
| Pages: |
530-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Grifone R |
| Year: |
2004 |
| Journal: |
Mol Cell Biol |
| Title: |
Six1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype. |
| Volume: |
24 |
| Issue: |
14 |
| Pages: |
6253-67 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suen AA |
| Year: |
2016 |
| Journal: |
Mol Cancer Res |
| Title: |
SIX1 Oncoprotein as a Biomarker in a Model of Hormonal Carcinogenesis and in Human Endometrial Cancer. |
| Volume: |
14 |
| Issue: |
9 |
| Pages: |
849-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McCoy EL |
| Year: |
2009 |
| Journal: |
Oral Dis |
| Title: |
Expression of Six1 homeobox gene during development of the mouse submandibular salivary gland. |
| Volume: |
15 |
| Issue: |
6 |
| Pages: |
407-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu H |
| Year: |
2017 |
| Journal: |
Carcinogenesis |
| Title: |
Six1 promotes colorectal cancer growth and metastasis by stimulating angiogenesis and recruiting tumor-associated macrophages. |
| Volume: |
38 |
| Issue: |
3 |
| Pages: |
281-292 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suen AA |
| Year: |
2019 |
| Journal: |
Mol Cancer Res |
| Title: |
SIX1 Regulates Aberrant Endometrial Epithelial Cell Differentiation and Cancer Latency Following Developmental Estrogenic Chemical Exposure. |
| Volume: |
17 |
| Issue: |
12 |
| Pages: |
2369-2382 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang T |
| Year: |
2017 |
| Journal: |
PLoS Genet |
| Title: |
Six1 is essential for differentiation and patterning of the mammalian auditory sensory epithelium. |
| Volume: |
13 |
| Issue: |
9 |
| Pages: |
e1006967 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baxi A |
| Year: |
2023 |
| Journal: |
Dev Dyn |
| Title: |
Transcriptomic analysis reveals the role of SIX1 in mouse cranial neural crest patterning and bone development. |
| Volume: |
252 |
| Issue: |
10 |
| Pages: |
1303-1315 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ando Z |
| Year: |
2005 |
| Journal: |
FEBS J |
| Title: |
Slc12a2 is a direct target of two closely related homeobox proteins, Six1 and Six4. |
| Volume: |
272 |
| Issue: |
12 |
| Pages: |
3026-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Le Grand F |
| Year: |
2012 |
| Journal: |
J Cell Biol |
| Title: |
Six1 regulates stem cell repair potential and self-renewal during skeletal muscle regeneration. |
| Volume: |
198 |
| Issue: |
5 |
| Pages: |
815-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Terakawa J |
| Year: |
2020 |
| Journal: |
Cell Death Differ |
| Title: |
SIX1 cooperates with RUNX1 and SMAD4 in cell fate commitment of Müllerian duct epithelium. |
| Volume: |
27 |
| Issue: |
12 |
| Pages: |
3307-3320 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ikeda K |
| Year: |
2010 |
| Journal: |
Int J Dev Biol |
| Title: |
Six1 is indispensable for production of functional progenitor cells during olfactory epithelial development. |
| Volume: |
54 |
| Issue: |
10 |
| Pages: |
1453-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takahashi M |
| Year: |
2020 |
| Journal: |
Dev Dyn |
| Title: |
Six1 is required for signaling center formation and labial-lingual asymmetry in developing lower incisors. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zou D |
| Year: |
2004 |
| Journal: |
Development |
| Title: |
Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes. |
| Volume: |
131 |
| Issue: |
22 |
| Pages: |
5561-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yajima H |
| Year: |
2014 |
| Journal: |
BMC Biol |
| Title: |
Six1 is a key regulator of the developmental and evolutionary architecture of sensory neurons in craniates. |
| Volume: |
12 |
|
| Pages: |
40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen B |
| Year: |
2009 |
| Journal: |
Dev Biol |
| Title: |
Initiation of olfactory placode development and neurogenesis is blocked in mice lacking both Six1 and Six4. |
| Volume: |
326 |
| Issue: |
1 |
| Pages: |
75-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bonnin MA |
| Year: |
2005 |
| Journal: |
Mech Dev |
| Title: |
Six1 is not involved in limb tendon development, but is expressed in limb connective tissue under Shh regulation. |
| Volume: |
122 |
| Issue: |
4 |
| Pages: |
573-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bosman EA |
| Year: |
2009 |
| Journal: |
Dev Biol |
| Title: |
Catweasel mice: a novel role for Six1 in sensory patch development and a model for branchio-oto-renal syndrome. |
| Volume: |
328 |
| Issue: |
2 |
| Pages: |
285-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kobayashi H |
| Year: |
2007 |
| Journal: |
Mech Dev |
| Title: |
Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects. |
| Volume: |
124 |
| Issue: |
4 |
| Pages: |
290-303 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6183328 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689419 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:6191305 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table S2 - E11.5 - Six1 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6183328 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689421 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:6191305 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
Table S2 - E13.5 - Six1 |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6183328 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689424 |
|
| Stage: |
TS24 |
| Assay Id: |
MGI:6191305 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
Table S2 - E15.5 - Six1 |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6183328 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689426 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:6191305 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
Table S2 - E18.5 - Six1 |
| Detected: |
false |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6183328 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6191305 |
| Age: |
postnatal day 4 |
|
|
| Specimen Label: |
Table S2 - P4 - Six1 |
| Detected: |
false |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6183328 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6191305 |
| Age: |
postnatal day 14 |
|
|
| Specimen Label: |
Table S2 - P14 - Six1 |
| Detected: |
false |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6183328 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6191305 |
| Age: |
postnatal day 28 |
|
|
| Specimen Label: |
Table S2 - P28 - Six1 |
| Detected: |
false |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Grifone R |
| Year: |
2005 |
| Journal: |
Development |
| Title: |
Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryo. |
| Volume: |
132 |
| Issue: |
9 |
| Pages: |
2235-49 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Niro C |
| Year: |
2010 |
| Journal: |
Dev Biol |
| Title: |
Six1 and Six4 gene expression is necessary to activate the fast-type muscle gene program in the mouse primary myotome. |
| Volume: |
338 |
| Issue: |
2 |
| Pages: |
168-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Oliver G |
| Year: |
1995 |
| Journal: |
Development |
| Title: |
Homeobox genes and connective tissue patterning. |
| Volume: |
121 |
| Issue: |
3 |
| Pages: |
693-705 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
El-Hashash AH |
| Year: |
2011 |
| Journal: |
Dev Biol |
| Title: |
Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. |
| Volume: |
353 |
| Issue: |
2 |
| Pages: |
242-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Freyer L |
| Year: |
2010 |
| Journal: |
Dev Dyn |
| Title: |
Canonical Wnt signaling modulates Tbx1, Eya1, and Six1 expression, restricting neurogenesis in the otic vesicle. |
| Volume: |
239 |
| Issue: |
6 |
| Pages: |
1708-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li J |
| Year: |
2020 |
| Journal: |
Nucleic Acids Res |
| Title: |
Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium. |
| Volume: |
48 |
| Issue: |
6 |
| Pages: |
2880-2896 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ahmed M |
| Year: |
2012 |
| Journal: |
Development |
| Title: |
EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear. |
| Volume: |
139 |
| Issue: |
11 |
| Pages: |
1965-77 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li X |
| Year: |
2003 |
| Journal: |
Nature |
| Title: |
Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. |
| Volume: |
426 |
| Issue: |
6964 |
| Pages: |
247-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Calpena E |
| Year: |
2022 |
| Journal: |
J Med Genet |
| Title: |
Unexpected role of SIX1 variants in craniosynostosis: expanding the phenotype of SIX1-related disorders. |
| Volume: |
59 |
| Issue: |
2 |
| Pages: |
165-169 |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|