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Search results 1 to 100 out of 139 for Slc10a2

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
6555 | SLC10A2
Type: gene
Organism: human
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Gene
100487141 | slc10a2
Type: gene
Organism: frog, western clawed
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Gene
key_41226 | SLC10A2
Type: gene
Organism: hamster, Chinese
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Gene
key_41227 | SLC10A2
Type: gene
Organism: rabbit, European
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Gene
29500 | Slc10a2
Type: gene
Organism: rat
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Gene
403448 | SLC10A2
Type: gene
Organism: dog, domestic
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Gene
467318 | SLC10A2
Type: gene
Organism: chimpanzee
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Gene
525823 | SLC10A2
Type: gene
Organism: cattle
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Gene
428018 | SLC10A2
Type: gene
Organism: chicken
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Gene
393329 | slc10a2
Type: gene
Organism: zebrafish
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Gene
702376 | SLC10A2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1201406 | Slc10a2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR030207 | SLC10A2
Type: Family
Description: Solute carrier family 10 member 2 (SLC10A2) is also known as ileal sodium/bile acid cotransporter (ASBT) as it plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine [, ]. It indirectly contributes to cholesterol homoeostasis [, ].
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Protein
P70172
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
Q6QQR9
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
Q0VBB8
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Publication
7592981 | -
First Author: Wong MH
Year: 1995
Journal: J Biol Chem
Title: Identification of a mutation in the ileal sodium-dependent bile acid transporter gene that abolishes transport activity.
Volume: 270
Issue: 45
Pages: 27228-34
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Publication
9109432 | -
First Author: Oelkers P
Year: 1997
Journal: J Clin Invest
Title: Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2).
Volume: 99
Issue: 8
Pages: 1880-7
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Publication
24498857 | -
First Author: Chothe PP
Year: 2014
Journal: Biochem J
Title: Resveratrol promotes degradation of the human bile acid transporter ASBT (SLC10A2).
Volume: 459
Issue: 2
Pages: 301-12
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Publication
16687134 | -
First Author: Kitayama K
Year: 2006
Journal: Eur J Pharmacol
Title: Novel non-systemic inhibitor of ileal apical Na+-dependent bile acid transporter reduces serum cholesterol levels in hamsters and monkeys.
Volume: 539
Issue: 1-2
Pages: 89-98
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Publication
15834632 | J:97646
First Author: Lyons MA
Year: 2005
Journal: Mamm Genome
Title: Single and interacting QTLs for cholesterol gallstones revealed in an intercross between mouse strains NZB and SM.
Volume: 16
Issue: 3
Pages: 152-63
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Publication
12819193 | J:85312
First Author: Dawson PA
Year: 2003
Journal: J Biol Chem
Title: Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice.
Volume: 278
Issue: 36
Pages: 33920-7
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Publication
31465442 | J:279004
First Author: Kemis JH
Year: 2019
Journal: PLoS Genet
Title: Genetic determinants of gut microbiota composition and bile acid profiles in mice.
Volume: 15
Issue: 8
Pages: e1008073
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Publication
15563450 | J:106032
First Author: Dawson PA
Year: 2005
Journal: J Biol Chem
Title: The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter.
Volume: 280
Issue: 8
Pages: 6960-8
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Protein Coding Gene
MGP_CAROLIEiJ_G0030804 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033339 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033320 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033251 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033320 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033034 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1201406 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033832 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032357 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033007 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033161 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033108 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033255 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033143 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033849 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032069 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032472 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021265 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031912 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10101301 | J:54780
First Author: Saeki T
Year: 1999
Journal: J Biochem
Title: Characterization, cDNA cloning, and functional expression of mouse ileal sodium-dependent bile acid transporter.
Volume: 125
Issue: 4
Pages: 846-51
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Publication
17823457 | J:129925
First Author: Jung D
Year: 2007
Journal: J Lipid Res
Title: FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorption.
Volume: 48
Issue: 12
Pages: 2693-700
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Publication
26210740 | J:225894
First Author: Raufman JP
Year: 2015
Journal: Carcinogenesis
Title: Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids.
Volume: 36
Issue: 10
Pages: 1193-200
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Publication
24841254 | J:216330
First Author: Naugler WE
Year: 2014
Journal: PLoS One
Title: Bile acid flux is necessary for normal liver regeneration.
Volume: 9
Issue: 5
Pages: e97426
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Publication
20616306 | J:163323
First Author: Halpern MD
Year: 2010
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Apical sodium-dependent bile acid transporter upregulation is associated with necrotizing enterocolitis.
Volume: 299
Issue: 3
Pages: G623-31
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Publication
11509565 | J:72178
First Author: Chen F
Year: 2001
Journal: J Biol Chem
Title: The role of AP-1 in the transcriptional regulation of the rat apical sodium-dependent bile acid transporter.
Volume: 276
Issue: 42
Pages: 38703-14
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GXD Expression
GXD Expression
     
Probe: MGI:6510492
Assay Type: RT-PCR
Annotation Date: 2021-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:6510584
Age: postnatal
Specimen Label: B6J
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6510492
Assay Type: RT-PCR
Annotation Date: 2021-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:6510584
Age: postnatal
Specimen Label: B6By
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6510606
Assay Type: Western blot
Annotation Date: 2021-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276428
Stage: TS28
Assay Id: MGI:6510607
Age: postnatal
Specimen Label: B6J
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6510606
Assay Type: Western blot
Annotation Date: 2021-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276428
Stage: TS28
Assay Id: MGI:6510607
Age: postnatal
Specimen Label: B6J
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6510606
Assay Type: Western blot
Annotation Date: 2021-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276428
Stage: TS28
Assay Id: MGI:6510607
Age: postnatal
Specimen Label: B6J
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6510606
Assay Type: Western blot
Annotation Date: 2021-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276428
Stage: TS28
Assay Id: MGI:6510607
Age: postnatal
Specimen Label: B6By
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6510606
Assay Type: Western blot
Annotation Date: 2021-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276428
Stage: TS28
Assay Id: MGI:6510607
Age: postnatal
Specimen Label: B6By
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6510606
Assay Type: Western blot
Annotation Date: 2021-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276428
Stage: TS28
Assay Id: MGI:6510607
Age: postnatal
Specimen Label: B6By
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691264
Age: postnatal adult
Image: BCM_2398595
Note: kidney
Specimen Label: BCM_2398595
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691264
Age: postnatal adult
Image: BCM_2398596
Note: kidney
Specimen Label: BCM_2398596
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691264
Age: postnatal adult
Image: BCM_2398597
Note: kidney
Specimen Label: BCM_2398597
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1902828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691264
Age: postnatal adult
Image: BCM_2398598
Specimen Label: BCM_2398598
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1902828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691264
Age: postnatal adult
Image: BCM_2398599
Specimen Label: BCM_2398599
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1902828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691264
Age: postnatal adult
Image: BCM_2398600
Specimen Label: BCM_2398600
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691264
Age: postnatal adult
Image: BCM_2398601
Note: vas deferens
Specimen Label: BCM_2398601
Specimen Num: 7
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691264
Age: postnatal adult
Image: BCM_2398602
Note: vas deferens
Specimen Label: BCM_2398602
Specimen Num: 8
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3283428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691264
Age: postnatal adult
Image: BCM_2398598
Specimen Label: BCM_2398598
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3283428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691264
Age: postnatal adult
Image: BCM_2398599
Specimen Label: BCM_2398599
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3283428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691264
Age: postnatal adult
Image: BCM_2398600
Specimen Label: BCM_2398600
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6510606
Assay Type: Immunohistochemistry
Annotation Date: 2021-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3542328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6510608
Age: postnatal
Note: Protein is on the apical membrane.
Specimen Label: 3F
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691264
Age: postnatal adult
Image: BCM_2398601
Specimen Label: BCM_2398601
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691264
Age: postnatal adult
Image: BCM_2398602
Specimen Label: BCM_2398602
Specimen Num: 8
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Publication
- | J:60842
   
First Author: Saeki T
Year: 1999
Journal: GenBank Submission
Title: House mouse; Musculus domesticus mRNA for ileal Na+-dependent bile acid transporter, partial cds
Pages: D87059
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Publication
36410025 | J:333190
First Author: Meadows V
Year: 2023
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Loss of apical sodium bile acid transporter alters bile acid circulation and reduces biliary damage in cholangitis.
Volume: 324
Issue: 1
Pages: G60-G77
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Publication
36787187 | J:334921
 
First Author: Truong JK
Year: 2023
Journal: JCI Insight
Title: Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice.
Volume: 8
Issue: 6
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Publication
9457686 | J:42394
First Author: Lammert F
Year: 1998
Journal: Mamm Genome
Title: Localization of the ileal sodium-bile salt cotransporter gene (Slc10a2) to mouse chromosome 8.
Volume: 9
Issue: 2
Pages: 173-4
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Publication
18292224 | J:132778
First Author: Rao A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The organic solute transporter alpha-beta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis.
Volume: 105
Issue: 10
Pages: 3891-6
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Publication
39214086 | J:354341
First Author: Peiper AM
Year: 2024
Journal: Cell Host Microbe
Title: Metabolic immaturity and breastmilk bile acid metabolites are central determinants of heightened newborn vulnerability to norovirus diarrhea.
Volume: 32
Issue: 9
Pages: 1488-1501.e5
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Publication
33895309 | J:320453
First Author: Zaufel A
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions.
Volume: 1867
Issue: 8
Pages: 166153
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Publication
23200860 | J:198860
First Author: Ito M
Year: 2013
Journal: Biochim Biophys Acta
Title: Disruption of Stard10 gene alters the PPARα-mediated bile acid homeostasis.
Volume: 1831
Issue: 2
Pages: 459-68
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Publication
23125159 | J:337164
First Author: Cherrington NJ
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: The hepatic bile acid transporters Ntcp and Mrp2 are downregulated in experimental necrotizing enterocolitis.
Volume: 304
Issue: 1
Pages: G48-56
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Publication
22542490 | J:320452
First Author: Lan T
Year: 2012
Journal: J Hepatol
Title: Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism.
Volume: 57
Issue: 2
Pages: 359-65
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Publication
19882669 | J:156027
First Author: Festing MH
Year: 2009
Journal: Genesis
Title: Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1.
Volume: 47
Issue: 12
Pages: 858-63
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Publication
23880190 | J:318171
First Author: Lan T
Year: 2013
Journal: Atherosclerosis
Title: Inhibition of ileal apical but not basolateral bile acid transport reduces atherosclerosis in apoE⁻/⁻ mice.
Volume: 229
Issue: 2
Pages: 374-80
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Publication
33828301 | J:334847
First Author: Chen ML
Year: 2021
Journal: Nature
Title: CAR directs T cell adaptation to bile acids in the small intestine.
Volume: 593
Issue: 7857
Pages: 147-151
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Publication
29262351 | J:259930
First Author: Cao W
Year: 2017
Journal: Immunity
Title: The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids.
Volume: 47
Issue: 6
Pages: 1182-1196.e10
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Publication
31080134 | J:284491
First Author: Pepe-Mooney BJ
Year: 2019
Journal: Cell Stem Cell
Title: Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration.
Volume: 25
Issue: 1
Pages: 23-38.e8
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Publication
18245842 | J:133501
First Author: Stylianou IM
Year: 2008
Journal: Genetics
Title: Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification.
Volume: 178
Issue: 3
Pages: 1795-805
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Publication
19679677 | J:154939
First Author: Cheng X
Year: 2009
Journal: Drug Metab Dispos
Title: Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.
Volume: 37
Issue: 11
Pages: 2178-85
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Publication
23747249 | J:199245
First Author: Vergnes L
Year: 2013
Journal: Cell Metab
Title: Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels.
Volume: 17
Issue: 6
Pages: 916-28
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Publication
27146480 | J:233745
First Author: Ferrell JM
Year: 2016
Journal: J Lipid Res
Title: Cholesterol 7α-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders.
Volume: 57
Issue: 7
Pages: 1144-54
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Publication
23676500 | J:201436
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First Author: University of California, Davis
Year: 2010
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First Author: The Gene Ontology Consortium
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Journal: Nucleic Acids Res
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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