Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
rabbit, European |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Solute carrier family 12 member 1 (SLC12A1 or NKCC2) is an apical absorptive Na-K-Cl co-transporterisoform. In contrast to the wide tissue distribution of NKCC1, expressionof the NKCC2 isoform is restricted to the vertebrate kidney, where it isinvolved in urinary concentration []. Subsequent studies revealed thatthree variants exist, differing by 31 amino acids, which are generatedby alternatively splicing. They show differential distributions withinthe kidney, suggesting they may subserve varying functions []. Mutations in the gene encoding the renal-specific isoform of the Na-K-Clco-transporter (NKCC2) give rise to Bartter's Syndrome Type 1, an inheritedkidney disease characterised by hypokalaemia, metabolic alkalosis,salt-wasting and hypotension [].The Na-K-Cl co-transporters are a family of integral membrane proteins thatare ubiquitously expressed in animal tissues, serving a variety offunctions. In cells of Cl-absorptive and Cl-secretory epithelia, Na-K-Clco-transport serves as the major Cl-entry pathway, and functions inconcert with other membrane ion channels and pumps to carry out nettransepithelial movement of salt. This vectorial transport of Cl-acrossepithelia is involved in the reabsorption of salt in the vertebrate kidney(which is crucial for urinary concentration), and in the secretion of saltin such tissues as the mammalian intestine and trachea. In addition,Na-K-Cl co-transport is known to play a role in cell volume regulation inmost mammalian cell types. The proteins mediate the coupled, electroneutraltransport of sodium, potassium and chloride ions across the plasma membraneof cells (with a stoichiometry of 1:1:2, respectively). Co-transport of allthree ions is obligatory, since absence of one is sufficient to prevent ionmovement. Their transport activity does not alter the cell's membranepotential, thus the driving force for the transport is determined solelyby the chemical gradients of the three transported ions; hence, undernormal physiological conditions, the direction will be inward.There are two distinct isoforms: one fromCl-secretory epithelia, NKCC1; and another, NKCC2, found specifically inthe diluting segment of the vertebrate kidney, a Cl-absorptive epithelium[]. They show lowish amino acid sequence identity (~58%); nevertheless,they have rather similar hydropathy profiles, with hydrophilic N- andC-termini, flanking a central hydrophobic domain. Their N-termini showconsiderable variation, unlike the central domain (containing the 12putative transmembrane (TM) domains) and their C-termini, which are wellconserved (~70%). Both isoforms are known to be glycosylated and, consistentwith this, consensus sites for N-linked glycosylation are located within thelarge hydrophilic loop between presumed TM domains 7 and 8. Sequencecomparisons with other cloned ion co-transporters reveals that Na-K-Clco-transporters belong to a superfamily of electroneutral cation-chlorideco-transporters, which includes the K-Cl co-transporter () and thethiazide-sensitive Na-Cl co-transporter. All share a similar predictedmembrane topology of 12 TM regions in a central hydrophobic domain,together with hydrophilic N- and C-termini that are likely cytoplasmic. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7790610 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:2804923 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:7790672 |
Age: |
embryonic day 15.5 |
Image: |
1c SLC12a1 E15.5 |
|
Specimen Label: |
1c SLC12a1 E15.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7790610 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1928027 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7790672 |
Age: |
postnatal day 0 |
Image: |
1c SLC12a1 P0 |
|
Specimen Label: |
1c SLC12a1 P0 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gamba G |
Year: |
1994 |
Journal: |
J Biol Chem |
Title: |
Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney. |
Volume: |
269 |
Issue: |
26 |
Pages: |
17713-22 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1095
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1090
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1090
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1090
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Payne JA |
Year: |
1995 |
Journal: |
Curr Opin Cell Biol |
Title: |
Molecular characterization of the epithelial Na-K-Cl cotransporter isoforms. |
Volume: |
7 |
Issue: |
4 |
Pages: |
493-503 |
|
•
•
•
•
•
|
Publication |
First Author: |
Simon DB |
Year: |
1998 |
Journal: |
Curr Opin Cell Biol |
Title: |
Mutations in Na(K)Cl transporters in Gitelman's and Bartter's syndromes. |
Volume: |
10 |
Issue: |
4 |
Pages: |
450-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Payne JA |
Year: |
1994 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Alternatively spliced isoforms of the putative renal Na-K-Cl cotransporter are differentially distributed within the rabbit kidney. |
Volume: |
91 |
Issue: |
10 |
Pages: |
4544-8 |
|
•
•
•
•
•
|
Allele |
Name: |
solute carrier family 12, member 1; targeted mutation 1, Johannes Loffing |
Allele Type: |
Targeted |
Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
Publication |
First Author: |
Bourqui L |
Year: |
2023 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
A novel mouse model for an inducible gene modification in the renal thick ascending limb. |
Volume: |
324 |
Issue: |
5 |
Pages: |
F446-F460 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kelly L |
Year: |
2019 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Impaired glucose tolerance, glucagon, and insulin responses in mice lacking the loop diuretic-sensitive Nkcc2a transporter. |
Volume: |
317 |
Issue: |
4 |
Pages: |
C843-C856 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kemter E |
Year: |
2010 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Mutation of the Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in mice is associated with severe polyuria and a urea-selective concentrating defect without hyperreninemia. |
Volume: |
298 |
Issue: |
6 |
Pages: |
F1405-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kemter E |
Year: |
2014 |
Journal: |
J Biomed Sci |
Title: |
Standardized, systemic phenotypic analysis of Slc12a1I299F mutant mice. |
Volume: |
21 |
|
Pages: |
68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vanden Heuvel GB |
Year: |
2006 |
Journal: |
Gene Expr Patterns |
Title: |
Expression of the basolateral Na-K-Cl cotransporter during mouse nephrogenesis and embryonic development. |
Volume: |
6 |
Issue: |
8 |
Pages: |
1000-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pietilä I |
Year: |
2011 |
Journal: |
Dev Biol |
Title: |
Secreted Wnt antagonist Dickkopf-1 controls kidney papilla development coordinated by Wnt-7b signalling. |
Volume: |
353 |
Issue: |
1 |
Pages: |
50-60 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Gillen CM |
Year: |
1996 |
Journal: |
J Biol Chem |
Title: |
Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family. |
Volume: |
271 |
Issue: |
27 |
Pages: |
16237-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oppermann M |
Year: |
2006 |
Journal: |
J Am Soc Nephrol |
Title: |
Macula densa control of renin secretion and preglomerular resistance in mice with selective deletion of the B isoform of the Na,K,2Cl co-transporter. |
Volume: |
17 |
Issue: |
8 |
Pages: |
2143-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oppermann M |
Year: |
2007 |
Journal: |
J Am Soc Nephrol |
Title: |
Renal function in mice with targeted disruption of the A isoform of the Na-K-2Cl co-transporter. |
Volume: |
18 |
Issue: |
2 |
Pages: |
440-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takahashi N |
Year: |
2000 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Uncompensated polyuria in a mouse model of Bartter's syndrome. |
Volume: |
97 |
Issue: |
10 |
Pages: |
5434-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takahashi N |
Year: |
2002 |
Journal: |
J Am Soc Nephrol |
Title: |
Posttranscriptional compensation for heterozygous disruption of the kidney-specific NaK2Cl cotransporter gene. |
Volume: |
13 |
Issue: |
3 |
Pages: |
604-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Plata C |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms. |
Volume: |
277 |
Issue: |
13 |
Pages: |
11004-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Igarashi P |
Year: |
1996 |
Journal: |
J Biol Chem |
Title: |
Cloning and kidney cell-specific activity of the promoter of the murine renal Na-K-C1 cotransporter gene. |
Volume: |
271 |
Issue: |
16 |
Pages: |
9666-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang J |
Year: |
1997 |
Journal: |
Mamm Genome |
Title: |
Linkage mapping of the Na-K-2Cl cotransporter gene (Slc12a1) to rat chromosome 3. |
Volume: |
8 |
Issue: |
5 |
Pages: |
379 |
|
•
•
•
•
•
|
Publication |
First Author: |
Plata C |
Year: |
1999 |
Journal: |
Am J Physiol |
Title: |
Isoforms of the Na-K-2Cl cotransporter in murine TAL II. Functional characterization and activation by cAMP. |
Volume: |
276 |
Issue: |
3 Pt 2 |
Pages: |
F359-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Castrop H |
Year: |
2008 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Isoforms of renal Na-K-2Cl cotransporter NKCC2: expression and functional significance. |
Volume: |
295 |
Issue: |
4 |
Pages: |
F859-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zaarour N |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
A highly conserved motif at the COOH terminus dictates endoplasmic reticulum exit and cell surface expression of NKCC2. |
Volume: |
284 |
Issue: |
32 |
Pages: |
21752-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schiessl IM |
Year: |
2013 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Dietary salt intake modulates differential splicing of the Na-K-2Cl cotransporter NKCC2. |
Volume: |
305 |
Issue: |
8 |
Pages: |
F1139-48 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5472009 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473281 |
Age: |
postnatal |
|
|
Specimen Label: |
Wild Type |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5472009 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473281 |
Age: |
postnatal |
|
|
Specimen Label: |
Wild Type |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5472009 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473281 |
Age: |
postnatal |
|
|
Specimen Label: |
Wild Type |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5472009 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473281 |
Age: |
postnatal |
|
|
Specimen Label: |
Knockout |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5472009 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473281 |
Age: |
postnatal |
|
|
Specimen Label: |
Knockout |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5472009 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473281 |
Age: |
postnatal |
|
|
Specimen Label: |
Knockout |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5472009 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473281 |
Age: |
postnatal |
|
|
Specimen Label: |
Knockout |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5472009 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473281 |
Age: |
postnatal |
|
|
Specimen Label: |
Wild Type |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5473330 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473332 |
Age: |
postnatal |
|
|
Specimen Label: |
Wild Type |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5473330 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473332 |
Age: |
postnatal |
|
|
Specimen Label: |
Wild Type |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5473330 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473332 |
Age: |
postnatal |
|
|
Specimen Label: |
Wild Type |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5473330 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473332 |
Age: |
postnatal |
|
|
Specimen Label: |
Wild Type |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5473330 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473332 |
Age: |
postnatal |
|
|
Specimen Label: |
Knockout |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5473330 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473332 |
Age: |
postnatal |
|
|
Specimen Label: |
Knockout |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5473330 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473332 |
Age: |
postnatal |
|
|
Specimen Label: |
Knockout |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5473330 |
Assay Type: |
Western blot |
Annotation Date: |
2013-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5473332 |
Age: |
postnatal |
|
|
Specimen Label: |
Knockout |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6357742 |
Age: |
postnatal adult |
|
|
Specimen Label: |
brain |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6357742 |
Age: |
postnatal adult |
|
|
Specimen Label: |
heart |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6357742 |
Age: |
postnatal adult |
|
|
Specimen Label: |
lung |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6357742 |
Age: |
postnatal adult |
|
|
Specimen Label: |
liver |
Detected: |
false |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6357742 |
Age: |
postnatal adult |
|
|
Specimen Label: |
spleen |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6357742 |
Age: |
postnatal adult |
|
|
Specimen Label: |
kidney |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6357742 |
Age: |
postnatal adult |
|
|
Specimen Label: |
intestine |
Detected: |
false |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6357742 |
Age: |
postnatal adult |
|
|
Specimen Label: |
testis |
Detected: |
false |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:1796228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6357742 |
Age: |
postnatal adult |
|
|
Specimen Label: |
ovary |
Detected: |
false |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737321 |
|
Stage: |
TS21 |
Assay Id: |
MGI:6357749 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
E13.5 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:6357749 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
E14.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737324 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6357749 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
E16.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737327 |
|
Stage: |
TS27 |
Assay Id: |
MGI:6357749 |
Age: |
postnatal day 1 |
|
|
Specimen Label: |
P1 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6357749 |
Age: |
postnatal day 8 |
|
|
Specimen Label: |
P8 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6357741 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6357749 |
Age: |
postnatal adult |
|
|
Specimen Label: |
A |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:31580 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1795228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6357754 |
Age: |
postnatal adult |
|
|
Specimen Label: |
renal cortex |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:31580 |
Assay Type: |
Northern blot |
Annotation Date: |
2019-08-28 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1927928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6357754 |
Age: |
postnatal adult |
|
|
Specimen Label: |
renal medulla |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7645917 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-06-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7645929 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Adult Kidney |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7645917 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-06-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737320 |
|
Stage: |
TS20 |
Assay Id: |
MGI:7645929 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
E12.5 Kidney |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7718658 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-09-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737327 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7718711 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
Cre- |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7718658 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-09-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737327 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7718711 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
Qpc-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7718658 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-09-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737323 |
|
Stage: |
TS23 |
Assay Id: |
MGI:7718770 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Cre- |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7718658 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-09-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737323 |
|
Stage: |
TS23 |
Assay Id: |
MGI:7718770 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Qpc-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4428051 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3516422 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5422500 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH2265; Specimen C2521 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|