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Search results 1 to 100 out of 113 for Surf1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
6834 | SURF1
Type: gene
Organism: human
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Gene
480681 | SURF1
Type: gene
Organism: dog, domestic
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Gene
746511 | SURF1
Type: gene
Organism: chimpanzee
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Gene
100139115 | SURF1
Type: gene
Organism: cattle
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Gene
557970 | surf1
Type: gene
Organism: zebrafish
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Gene
722212 | SURF1
Type: gene
Organism: macaque, rhesus
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Gene
549543 | surf1
Type: gene
Organism: frog, western clawed
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Gene
64463 | Surf1
Type: gene
Organism: rat
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Gene
417157 | SURF1
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:98443 | Surf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10746561 | J:61390
First Author: Poyau A
Year: 2000
Journal: Hum Genet
Title: Missense mutations in SURF1 associated with deficient cytochrome c oxidase assembly in Leigh syndrome patients.
Volume: 106
Issue: 2
Pages: 194-205
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Publication
17210671 | J:117871
First Author: Dell'agnello C
Year: 2007
Journal: Hum Mol Genet
Title: Increased longevity and refractoriness to Ca(2+)-dependent neurodegeneration in Surf1 knockout mice.
Volume: 16
Issue: 4
Pages: 431-44
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Publication
26804654 | J:256258
First Author: Kovářová N
Year: 2016
Journal: Biochim Biophys Acta
Title: Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects.
Volume: 1862
Issue: 4
Pages: 705-715
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Publication
21167962 | J:192149
First Author: Stettner GM
Year: 2011
Journal: Mitochondrion
Title: Hypoxic and hypercapnic challenges unveil respiratory vulnerability of Surf1 knockout mice, an animal model of Leigh syndrome.
Volume: 11
Issue: 3
Pages: 413-20
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Publication
12566387 | J:81773
First Author: Agostino A
Year: 2003
Journal: Hum Mol Genet
Title: Constitutive knockout of Surf1 is associated with high embryonic lethality, mitochondrial disease and cytochrome c oxidase deficiency in mice.
Volume: 12
Issue: 4
Pages: 399-413
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Publication
23838831 | J:284999
First Author: Lin AL
Year: 2013
Journal: J Cereb Blood Flow Metab
Title: Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice.
Volume: 33
Issue: 10
Pages: 1605-11
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Publication
24911525 | J:248388
First Author: Pulliam DA
Year: 2014
Journal: Biochem J
Title: Complex IV-deficient Surf1(-/-) mice initiate mitochondrial stress responses.
Volume: 462
Issue: 2
Pages: 359-71
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Publication
21723506 | J:176080
First Author: Viscomi C
Year: 2011
Journal: Cell Metab
Title: In vivo correction of COX deficiency by activation of the AMPK/PGC-1α axis.
Volume: 14
Issue: 1
Pages: 80-90
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Protein Coding Gene
MGP_CAROLIEiJ_G0023328 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025500 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025477 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025447 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025234 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_98443 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025917 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024697 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025212 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025345 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025307 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025431 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025338 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025976 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024445 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024766 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024785 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024245 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
34473622 | J:332707
   
First Author: Solano Fonseca R
Year: 2021
Journal: Elife
Title: Glycolytic preconditioning in astrocytes mitigates trauma-induced neurodegeneration.
Volume: 10
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Publication
23241310 | J:197658
First Author: Deepa SS
Year: 2013
Journal: FASEB J
Title: Improved insulin sensitivity associated with reduced mitochondrial complex IV assembly and activity.
Volume: 27
Issue: 4
Pages: 1371-80
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Publication
8034020 | J:18975
First Author: Gaston K
Year: 1994
Journal: FEBS Lett
Title: YY1 is involved in the regulation of the bi-directional promoter of the Surf-1 and Surf-2 genes.
Volume: 347
Issue: 2-3
Pages: 289-94
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GXD Expression
GXD Expression
     
Probe: MGI:2651412
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:2651431
Age: embryonic day 7.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2651412
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:2651431
Age: embryonic day 7.5
Specimen Label: -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2651412
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:2651431
Age: embryonic day 7.5
Specimen Label: -/-
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2651412
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:2651431
Age: embryonic day 7.5
Specimen Label: -/-
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2651412
Assay Type: RT-PCR
Annotation Date: 2003-03-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:2651431
Age: embryonic day 7.5
Specimen Label: -/-
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:2651419
Assay Type: Western blot
Annotation Date: 2003-03-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2651441
Age: postnatal
Specimen Label: -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2651419
Assay Type: Western blot
Annotation Date: 2003-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2651441
Age: postnatal
Specimen Label: +/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2651419
Assay Type: Western blot
Annotation Date: 2003-03-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651441
Age: postnatal
Specimen Label: -/-
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:2651419
Assay Type: Western blot
Annotation Date: 2003-03-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2651441
Age: postnatal
Specimen Label: +/+
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:2651412
Assay Type: RT-PCR
Annotation Date: 2003-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2651567
Age: postnatal adult
Specimen Label: -/-
Detected: false
Specimen Num: 1
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Publication
- | J:68262
   
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, clone MGC: 6703, mRNA, complete cds
Pages: BC004755
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Publication
3221868 | J:9602
First Author: Huxley C
Year: 1988
Journal: Mol Cell Biol
Title: One of the tightly clustered genes of the mouse surfeit locus is a highly expressed member of a multigene family whose other members are predominantly processed pseudogenes.
Volume: 8
Issue: 9
Pages: 3898-905
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Publication
3025660 | J:29566
First Author: Williams TJ
Year: 1986
Journal: Mol Cell Biol
Title: The MES-1 murine enhancer element is closely associated with the heterogeneous 5' ends of two divergent transcription units.
Volume: 6
Issue: 12
Pages: 4558-69
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Publication
8790375 | J:35250
First Author: Korfhagen TR
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Altered surfactant function and structure in SP-A gene targeted mice.
Volume: 93
Issue: 18
Pages: 9594-9
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Publication
2300057 | J:10274
First Author: Huxley C
Year: 1990
Journal: Mol Cell Biol
Title: The mouse surfeit locus contains a cluster of six genes associated with four CpG-rich islands in 32 kilobases of genomic DNA.
Volume: 10
Issue: 2
Pages: 605-14
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Publication
8639267 | J:32572
First Author: Magoulas C
Year: 1996
Journal: DNA Cell Biol
Title: The Surf-6 gene of the mouse surfeit locus encodes a novel nucleolar protein.
Volume: 15
Issue: 4
Pages: 305-16
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Publication
29660116 | J:266664
First Author: Simard ML
Year: 2018
Journal: J Pathol
Title: A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency.
Volume: 245
Issue: 3
Pages: 311-323
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Publication
2648130 | J:9681
First Author: Giallongo A
Year: 1989
Journal: Mol Cell Biol
Title: Ribosomal protein L7a is encoded by a gene (Surf-3) within the tightly clustered mouse surfeit locus.
Volume: 9
Issue: 1
Pages: 224-31
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Publication
2453062 | J:9177
First Author: Williams T
Year: 1988
Journal: Proc Natl Acad Sci U S A
Title: The mouse surfeit locus contains a very tight cluster of four "housekeeping" genes that is conserved through evolution.
Volume: 85
Issue: 10
Pages: 3527-30
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Publication
8140422 | J:29556
First Author: Zhong Z
Year: 1994
Journal: Science
Title: Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6.
Volume: 264
Issue: 5155
Pages: 95-8
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Publication
19007875 | J:146582
First Author: Swindell WR
Year: 2009
Journal: Exp Gerontol
Title: Accelerated failure time models provide a useful statistical framework for aging research.
Volume: 44
Issue: 3
Pages: 190-200
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Publication
- | J:38089
First Author: Pilz A
Year: 1996
Journal: Mouse Genome
Title: High resolution genetic linkage analysis of mouse Chromosome 2 in the region of homology with human Chromosome 9
Volume: 94
Issue: 4
Pages: 877-9
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Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
10647889 | -
First Author: Teraoka M
Year: 1999
Journal: Hum Genet
Title: Two novel mutations of SURF1 in Leigh syndrome with cytochrome c oxidase deficiency.
Volume: 105
Issue: 6
Pages: 560-3
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DO Term
DOID:0110187 | Charcot-Marie-Tooth disease type 4K
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DO Term
DOID:0070491 | mitochondrial complex IV deficiency nuclear type 1
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Publication
9843204 | J:51230
First Author: Zhu Z
Year: 1998
Journal: Nat Genet
Title: SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome.
Volume: 20
Issue: 4
Pages: 337-43
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Publication
20624914 | -
First Author: Bestwick M
Year: 2010
Journal: Mol Cell Biol
Title: Analysis of Leigh syndrome mutations in the yeast SURF1 homolog reveals a new member of the cytochrome oxidase assembly factor family.
Volume: 30
Issue: 18
Pages: 4480-91
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Protein Domain
IPR002994 | Surf1/Shy1
Type: Family
Description: This entry includes SURF1 and Shy1 proteins. The surfeit locus 1 gene (SURF1 or surf-1) encodes a conserved protein of about 300 amino-acid residues that seems to be involved in the biogenesis ofcytochrome c oxidase []. Vertebrate SURF1 is evolutionary related to yeastprotein Shy1, which is a mitochondrial inner membrane protein required for assembly of cytochrome c oxidase []. There seems to be two transmembrane regions in these proteins,one in the N-terminal, the other in the C-terminal.Defects in SURF1 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterised by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency [, , ].
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Protein Domain
IPR045214 | Surf1/Surf4
Type: Family
Description: This entry includes SURF1 and Shy1 proteins. The surfeit locus 1 gene (SURF1 or surf-1) encodes a conserved protein of about 300 amino-acid residues that seems to be involved in the biogenesis ofcytochrome c oxidase []. Vertebrate SURF1 is evolutionary related to yeastprotein Shy1, which is a mitochondrial inner membrane protein required for assembly of cytochrome c oxidase []. There seems to be two transmembrane regions in these proteins,one in the N-terminal, the other in the C-terminal.Defects in SURF1 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterised by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency [, , ]. The surfeit locus gene SURF4 (or surf-4) encodes a conserved integral eukaryotic membrane protein of about 270 to 300 amino-acid residues that seems to be located in the endoplasmic reticulum [].
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Protein
P09925
Organism: Mus musculus/domesticus
Length: 306  
Fragment?: false
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Protein
A0A0A6YVY3
Organism: Mus musculus/domesticus
Length: 63  
Fragment?: true
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Protein
Q3U3J6
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: false
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Protein
I6L9E0
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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