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Search results 1 to 100 out of 107 for Tbl1x

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
6907 | TBL1X
Type: gene
Organism: human
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Gene
100145441 | tbl1x
Type: gene
Organism: frog, western clawed
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Gene
106995151 | TBL1X
Type: gene
Organism: macaque, rhesus
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Gene
302711 | Tbl1x
Type: gene
Organism: rat
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Gene
611017 | TBL1X
Type: gene
Organism: dog, domestic
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Gene
741354 | TBL1X
Type: gene
Organism: chimpanzee
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Gene
515972 | TBL1X
Type: gene
Organism: cattle
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Gene
560294 | tbl1x
Type: gene
Organism: zebrafish
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Protein Coding Gene
MGI:1336172 | Tbl1x
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
   
Probe: MGI:4354553
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270422
Stage: TS22
Assay Id: MGI:4354923
Age: embryonic day 14.5
Image: 5F & Table S5 - Tbl1x
Specimen Label: 5F & Table S5 - Tbl1x
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4354553
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3271122
Stage: TS22
Assay Id: MGI:4354923
Age: embryonic day 14.5
Image: 5F & Table S5 - Tbl1x
Note: There is no expression in either the upper or lower cortical plate.
Specimen Label: 5F & Table S5 - Tbl1x
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4354553
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354923
Age: embryonic day 14.5
Image: 5F & Table S5 - Tbl1x
Specimen Label: 5F & Table S5 - Tbl1x
Detected: true
Specimen Num: 1
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Publication
38381448 | J:350764
 
First Author: Hu Y
Year: 2024
Journal: J Mol Endocrinol
Title: Mutant Tbl1x male mice have a short life span and do not breed: unexpected findings.
Volume: 73
Issue: 1
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Publication
28348241 | J:242147
First Author: Kruusvee V
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.
Volume: 114
Issue: 16
Pages: E3243-E3250
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Publication
26070566 | J:224604
First Author: Huang J
Year: 2015
Journal: J Biol Chem
Title: Exchange Factor TBL1 and Arginine Methyltransferase PRMT6 Cooperate in Protecting G Protein Pathway Suppressor 2 (GPS2) from Proteasomal Degradation.
Volume: 290
Issue: 31
Pages: 19044-54
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Publication
14980219 | J:88316
First Author: Perissi V
Year: 2004
Journal: Cell
Title: A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors.
Volume: 116
Issue: 4
Pages: 511-26
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Protein Coding Gene
MGP_CAROLIEiJ_G0033202 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035869 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035856 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035776 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035836 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035548 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1336172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036368 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034837 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035521 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035678 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035619 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035764 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035654 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0036393 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034533 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034973 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031746 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0034367 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
21189284 | J:169184
First Author: Ramadoss S
Year: 2011
Journal: Mol Cell Biol
Title: Transducin β-like protein 1 recruits nuclear factor κB to the target gene promoter for transcriptional activation.
Volume: 31
Issue: 5
Pages: 924-34
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GXD Expression
GXD Expression
   
Probe: MGI:5001526
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542080
Age: embryonic day 15.5
Image: GUDMAP:10233
Specimen Label: GUDMAP:10233
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001526
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542080
Age: embryonic day 15.5
Image: GUDMAP:10233
Specimen Label: GUDMAP:10233
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001526
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542080
Age: embryonic day 15.5
Image: GUDMAP:10233
Specimen Label: GUDMAP:10233
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001526
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2854023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542080
Age: embryonic day 15.5
Image: GUDMAP:10233
Specimen Label: GUDMAP:10233
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001526
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542080
Age: embryonic day 15.5
Image: GUDMAP:10233
Specimen Label: GUDMAP:10233
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001526
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542080
Age: embryonic day 15.5
Image: GUDMAP:10233
Specimen Label: GUDMAP:10233
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4354553
Assay Type: RNA in situ
Annotation Date: 2023-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7516941
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001526
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542080
Age: embryonic day 15.5
Image: GUDMAP:10233
Specimen Label: GUDMAP:10233
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001526
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542080
Age: embryonic day 15.5
Image: GUDMAP:10233
Specimen Label: GUDMAP:10233
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001526
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542080
Age: embryonic day 15.5
Image: GUDMAP:10233
Specimen Label: GUDMAP:10233
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001526
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542080
Age: embryonic day 15.5
Image: GUDMAP:10233
Specimen Label: GUDMAP:10233
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001526
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542080
Age: embryonic day 15.5
Image: GUDMAP:10233
Specimen Label: GUDMAP:10233
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001526
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542080
Age: embryonic day 15.5
Image: GUDMAP:10233
Specimen Label: GUDMAP:10233
Detected: true
Specimen Num: 1
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Publication
- | J:65936
   
First Author: Rugarli EI
Year: 1999
Journal: GenBank Submission
Title: Mus musculus partial Tbl1 gene
Pages: F38006
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Publication
26070712 | J:233550
First Author: Stoy C
Year: 2015
Journal: EMBO Mol Med
Title: Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy.
Volume: 7
Issue: 8
Pages: 1048-62
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Publication
21459324 | J:172247
First Author: Kulozik P
Year: 2011
Journal: Cell Metab
Title: Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.
Volume: 13
Issue: 4
Pages: 389-400
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Publication
9880679 | J:52006
First Author: Disteche CM
Year: 1998
Journal: Mamm Genome
Title: Mapping of the murine tbl1 gene reveals a new rearrangement between mouse and human X Chromosomes.
Volume: 9
Issue: 12
Pages: 1062-4
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Publication
23770565 | J:203745
First Author: Lyst MJ
Year: 2013
Journal: Nat Neurosci
Title: Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor.
Volume: 16
Issue: 7
Pages: 898-902
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Publication
15695367 | J:98538
First Author: Ishizuka T
Year: 2005
Journal: Mol Endocrinol
Title: The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor.
Volume: 19
Issue: 6
Pages: 1443-51
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Publication
27646874 | J:251534
First Author: Jeon BN
Year: 2016
Journal: Biochim Biophys Acta
Title: Zbtb7c is a molecular 'off' and 'on' switch of Mmp gene transcription.
Volume: 1859
Issue: 11
Pages: 1429-1439
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Publication
16127449 | J:101497
First Author: Pascual G
Year: 2005
Journal: Nature
Title: A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.
Volume: 437
Issue: 7059
Pages: 759-63
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Publication
16783646 | J:110030
First Author: Saba L
Year: 2006
Journal: Mamm Genome
Title: Candidate genes and their regulatory elements: alcohol preference and tolerance.
Volume: 17
Issue: 6
Pages: 669-88
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Publication
15728386 | J:96883
First Author: Olson LE
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Barx2 functions through distinct corepressor classes to regulate hair follicle remodeling.
Volume: 102
Issue: 10
Pages: 3708-13
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Publication
19521500 | J:149737
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 2
Description: F-box-like/WD repeat-containing protein TBL1X
Type: chain
End: 527
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Protein
Q9QXE7
Organism: Mus musculus/domesticus
Length: 527  
Fragment?: false
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Publication
10330347 | -
First Author: Bassi MT
Year: 1999
Journal: Am J Hum Genet
Title: X-linked late-onset sensorineural deafness caused by a deletion involving OA1 and a novel gene containing WD-40 repeats.
Volume: 64
Issue: 6
Pages: 1604-16
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DO Term
DOID:0111837 | congenital nongoitrous hypothyroidism 8
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Publication
11711434 | -
First Author: Pijnappel WW
Year: 2001
Journal: Genes Dev
Title: The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.
Volume: 15
Issue: 22
Pages: 2991-3004
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Publication
11032805 | -
First Author: Boulton SJ
Year: 2000
Journal: EMBO J
Title: A role for Ebi in neuronal cell cycle control.
Volume: 19
Issue: 20
Pages: 5376-86
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Publication
33708771 | J:314337
 
First Author: Mastrototaro G
Year: 2021
Journal: Front Cell Dev Biol
Title: TBL1XR1 Ensures Balanced Neural Development Through NCOR Complex-Mediated Regulation of the MAPK Pathway.
Volume: 9
Pages: 641410
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Publication
18356294 | -
First Author: Zhu J
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Involvement of Arabidopsis HOS15 in histone deacetylation and cold tolerance.
Volume: 105
Issue: 12
Pages: 4945-50
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Protein Domain
IPR045183 | Ebi-like
Type: Family
Description: This entry includes a group of F-box-like/WD repeat-containing proteins, including Hif2/Sif2 from yeasts, Ebi from Drosophila melanogaster, TBL1X /TBL1XR1 from humans and HOS15 from Arabidopsis. Hif2/Sif2 is part of the set3 histone deacetylase complex involved in chromatin remodeling and transcription regulation []. Ebi promotes the degradation of a repressor of neuronal differentiation (Ttk88) and also limits S phase entry []. TBL1X /TBL1XR1 act as a bridge between the corepressor protein and histones by interacting with both of them within the complex. The N terminus of TBL1X interacts with the N termini of both H2B and H4 histones, and the first three C-terminal WD40-repeats of TBL1X interact with the corepressor complex []. TBL1X /TBL1XR1 serve as specific adaptors for the recruitment of the ubiquitin conjugating/19S proteasome complex []and are important for both formation and dismantling of the NCOR complex, which is a corepressor complex. Mutations of the TBL1XR1 gene have been linked to several neurodevelopmental disorders, such as spanning from autism spectrum disorders (ASD), West syndrome, schizophrenia (SCZ), intellectual disability [].HOS15 represses genes associated with abiotic stress tolerance through histone deacetylation in Arabidopsis [].
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Protein
A0A0J9YUR3
Organism: Mus musculus/domesticus
Length: 74  
Fragment?: true
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Protein
A0A0J9YUE3
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: true
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Protein
A0A0J9YVC9
Organism: Mus musculus/domesticus
Length: 54  
Fragment?: true
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Protein
Q8BR49
Organism: Mus musculus/domesticus
Length: 999  
Fragment?: true
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