| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry represents a family of transmembrane proteins, which function as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation []. The secreted TMEM98 form promotes differentiation of T helper 1 cells (Th1) []. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fu W |
| Year: |
2015 |
| Journal: |
J Interferon Cytokine Res |
| Title: |
The Secreted Form of Transmembrane Protein 98 Promotes the Differentiation of T Helper 1 Cells. |
| Volume: |
35 |
| Issue: |
9 |
| Pages: |
720-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
van der Wal T |
| Year: |
2020 |
| Journal: |
PLoS One |
| Title: |
TMEM98 is a negative regulator of FRAT mediated Wnt/ß-catenin signalling. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
e0227435 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hassall MM |
| Year: |
2023 |
| Journal: |
Sci Rep |
| Title: |
Phenotypic consequences of a nanophthalmos-associated TMEM98 variant in human and mouse. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
11017 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cross SH |
| Year: |
2019 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Missense Mutations in the Human Nanophthalmos Gene TMEM98 Cause Retinal Defects in the Mouse. |
| Volume: |
60 |
| Issue: |
8 |
| Pages: |
2875-2887 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
226
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cross SH |
| Year: |
2020 |
| Journal: |
PLoS Genet |
| Title: |
The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification. |
| Volume: |
16 |
| Issue: |
4 |
| Pages: |
e1008583 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang H |
| Year: |
2018 |
| Journal: |
J Neurosci |
| Title: |
Interactive Repression of MYRF Self-Cleavage and Activity in Oligodendrocyte Differentiation by TMEM98 Protein. |
| Volume: |
38 |
| Issue: |
46 |
| Pages: |
9829-9839 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285630 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757727 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:6285648 |
| Age: |
postnatal day 0 |
| Image: |
1 |
|
| Specimen Label: |
P0 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285630 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6285648 |
| Age: |
postnatal day 4 |
| Image: |
1 |
|
| Specimen Label: |
P4 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285630 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6285648 |
| Age: |
postnatal day 7 |
| Image: |
1 |
|
| Specimen Label: |
P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285630 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6285648 |
| Age: |
postnatal day 15 |
| Image: |
1 |
|
| Specimen Label: |
P15 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285630 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6285648 |
| Age: |
postnatal adult |
| Image: |
1 |
|
| Specimen Label: |
Adult |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360292 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-09-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6360492 |
| Age: |
postnatal day 7 |
| Image: |
8 |
|
| Specimen Label: |
Myrf+/fl |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360292 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-09-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6360492 |
| Age: |
postnatal day 7 |
| Image: |
8 |
|
| Specimen Label: |
Rxcre;Myrf+/fl |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360292 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-09-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6360492 |
| Age: |
postnatal day 7 |
| Image: |
8 |
|
| Specimen Label: |
Rxcre;Myrf fl/fl |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360292 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6360540 |
| Age: |
postnatal day 22 |
| Image: |
8 |
|
| Specimen Label: |
Myrf+/fl |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360292 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6360540 |
| Age: |
postnatal day 22 |
| Image: |
8 |
|
| Specimen Label: |
Rxcre;Myrf+/fl |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360292 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2019-09-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6360540 |
| Age: |
postnatal day 22 |
| Image: |
8 |
|
| Specimen Label: |
Rxcre;Myrf fl/fl |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3579526 |
| Pattern: |
Regionally restricted |
| Stage: |
TS26 |
| Assay Id: |
MGI:6285631 |
| Age: |
embryonic day 18.5 |
| Image: |
1A |
| Note: |
Expressed in the ventral white matter. |
| Specimen Label: |
1A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3579528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 15 |
| Image: |
1D |
|
| Specimen Label: |
1D |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717223 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:6360315 |
| Age: |
embryonic day 15.5 |
| Image: |
8C left |
|
| Specimen Label: |
8C left |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717223 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:6360315 |
| Age: |
embryonic day 15.5 |
| Image: |
8C middle |
|
| Specimen Label: |
8C middle |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717223 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:6360315 |
| Age: |
embryonic day 15.5 |
| Image: |
8C right |
|
| Specimen Label: |
8C right |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6360316 |
| Age: |
postnatal day 7 |
| Image: |
8D left |
|
| Specimen Label: |
8D left |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6360316 |
| Age: |
postnatal day 7 |
| Image: |
8D middle |
|
| Specimen Label: |
8D middle |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6360316 |
| Age: |
postnatal day 7 |
| Image: |
8D right |
| Note: |
Decreased expression and altered localization compared to controls. |
| Specimen Label: |
8D right |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6360316 |
| Age: |
postnatal day 22 |
| Image: |
8E left |
|
| Specimen Label: |
8E left |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6360316 |
| Age: |
postnatal day 22 |
| Image: |
8E middle |
|
| Specimen Label: |
8E middle |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6360316 |
| Age: |
postnatal day 22 |
| Image: |
8E right |
| Note: |
Decreased expression and altered localization compared to controls. |
| Specimen Label: |
8E right |
|
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717227 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:6360315 |
| Age: |
postnatal day 3 |
| Image: |
S10 P3 upper |
|
| Specimen Label: |
S10 P3 upper |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717227 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:6360315 |
| Age: |
postnatal day 3 |
| Image: |
S10 P3 middle |
|
| Specimen Label: |
S10 P3 middle |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717227 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:6360315 |
| Age: |
postnatal day 3 |
| Image: |
S10 P3 lower |
| Note: |
A profound reduction in staining compared with the controls, with a small fraction of cells with diffuse cellular localization pattern. |
| Specimen Label: |
S10 P3 lower |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6360315 |
| Age: |
postnatal day 14 |
| Image: |
S10 P14 upper |
|
| Specimen Label: |
S10 P14 upper |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6360315 |
| Age: |
postnatal day 14 |
| Image: |
S10 P14 middle |
|
| Specimen Label: |
S10 P14 middle |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6360315 |
| Age: |
postnatal day 14 |
| Image: |
S10 P14 lower |
| Note: |
A profound reduction in staining compared with the controls, with a small fraction of cells with diffuse cellular localization pattern. |
| Specimen Label: |
S10 P14 lower |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6360315 |
| Age: |
postnatal day 22 |
| Image: |
S10 P22 upper |
|
| Specimen Label: |
S10 P22 upper |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6360315 |
| Age: |
postnatal day 22 |
| Image: |
S10 P22 middle |
|
| Specimen Label: |
S10 P22 middle |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6360309 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2019-09-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6360315 |
| Age: |
postnatal day 22 |
| Image: |
S10 P22 lower |
| Note: |
A profound reduction in staining compared with the controls, with a small fraction of cells with diffuse cellular localization pattern. |
| Specimen Label: |
S10 P22 lower |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3523528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 15 |
| Image: |
1F |
|
| Specimen Label: |
1F |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3525328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 15 |
| Image: |
1E |
|
| Specimen Label: |
1E |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3579228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 15 |
| Image: |
1D |
|
| Specimen Label: |
1D |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 4 |
| Image: |
1B |
| Note: |
Increased expression. |
| Specimen Label: |
1B |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 7 |
| Image: |
1C |
| Note: |
Increased expression. Highest expression. |
| Specimen Label: |
1C |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 7 |
| Image: |
2A/B |
| Note: |
Mostly coexpressed with the Sox10, which expressed in oligodendrocyte progenitor cells and mature oligodendrocytes. |
| Specimen Label: |
2A/B |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 7 |
| Image: |
2C/D |
| Note: |
Mostly coexpressed with Apc, which expressed in the young differentiated oligodendrocytes. |
| Specimen Label: |
2C/D |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 7 |
| Image: |
2E/F |
| Note: |
Mostly coexpressed with Myrf, which expressed in postmitotic myelinating oligodendrocytes. |
| Specimen Label: |
2E/F |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 7 |
| Image: |
2G/I |
| Note: |
Not expressed in Pdgfra+ immature oligodendrocyte progenitor cells. |
| Specimen Label: |
2G/I |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757727 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 3 |
| Image: |
2J |
|
| Specimen Label: |
2J |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757727 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 3 |
| Image: |
2K |
| Note: |
Severely decreased expression. |
| Specimen Label: |
2K |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757727 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 3 |
| Image: |
2L |
|
| Specimen Label: |
2L |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6285622 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2019-04-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757727 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:6285631 |
| Age: |
postnatal day 3 |
| Image: |
2M |
| Note: |
Severely decreased expression. |
| Specimen Label: |
2M |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Garnai SJ |
| Year: |
2019 |
| Journal: |
PLoS Genet |
| Title: |
Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice. |
| Volume: |
15 |
| Issue: |
5 |
| Pages: |
e1008130 |
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•
•
•
•
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| First Author: |
Thaung C |
| Year: |
2002 |
| Journal: |
Hum Mol Genet |
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Novel ENU-induced eye mutations in the mouse: models for human eye disease. |
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755-67 |
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Nat Commun |
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Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen. |
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3540 |
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•
•
•
•
•
|
| Publication |
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MouseBookTM |
| Year: |
2005 |
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Unpublished |
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Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK. |
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•
•
•
•
•
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| Publication |
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Tang T |
| Year: |
2010 |
| Journal: |
Nat Biotechnol |
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A mouse knockout library for secreted and transmembrane proteins. |
| Volume: |
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•
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•
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Lexicon Genetics, Inc |
| Year: |
2011 |
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Database Download |
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MGI download of Lexicon knockout data |
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| First Author: |
Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP) |
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2011 |
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Database Release |
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Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal |
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Mouse screen reveals multiple new genes underlying mouse and human hearing loss. |
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•
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Velocigene |
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2008 |
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MGI Direct Data Submission |
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Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
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•
•
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Wellcome Trust Sanger Institute |
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2010 |
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MGI Direct Data Submission |
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Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
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Database Release |
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Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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The transcriptional landscape of the mammalian genome. |
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MGD Nomenclature Committee |
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Nomenclature Committee Use |
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