| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
TNFSF9, also known as 4-1BBL, is a member of the tumor necrosis factor (TNF) superfamily and is the ligand for the TNFR superfamily receptor, 4-1BB. 4-1BB plays an immunomodulatory role in T cells and NK cells. Human h4-1BB has been targeted with agonists in cancer immunotherapy. The structure of 4-1BBL has be revealed [, , ]. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
309
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
309
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
309
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gilbreth RN |
| Year: |
2018 |
| Journal: |
J Biol Chem |
| Title: |
Crystal structure of the human 4-1BB/4-1BBL complex. |
| Volume: |
293 |
| Issue: |
25 |
| Pages: |
9880-9891 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bitra A |
| Year: |
2018 |
| Journal: |
J Biol Chem |
| Title: |
Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier. |
| Volume: |
293 |
| Issue: |
26 |
| Pages: |
9958-9969 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Won EY |
| Year: |
2010 |
| Journal: |
J Biol Chem |
| Title: |
The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily. |
| Volume: |
285 |
| Issue: |
12 |
| Pages: |
9202-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Foda BM |
| Year: |
2020 |
| Journal: |
J Immunol |
| Title: |
The CD137 Ligand Is Important for Type 1 Diabetes Development but Dispensable for the Homeostasis of Disease-Suppressive CD137+ FOXP3+ Regulatory CD4 T Cells. |
| Volume: |
204 |
| Issue: |
11 |
| Pages: |
2887-2899 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fuse S |
| Year: |
2007 |
| Journal: |
J Immunol |
| Title: |
CD8+ T cell dysfunction and increase in murine gammaherpesvirus latent viral burden in the absence of 4-1BB ligand. |
| Volume: |
178 |
| Issue: |
8 |
| Pages: |
5227-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wakley AA |
| Year: |
2018 |
| Journal: |
eNeuro |
| Title: |
Contribution of CD137L to Sensory Hypersensitivity in a Murine Model of Neuropathic Pain. |
| Volume: |
5 |
| Issue: |
5 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dawicki W |
| Year: |
2004 |
| Journal: |
Eur J Immunol |
| Title: |
Expression and function of 4-1BB during CD4 versus CD8 T cell responses in vivo. |
| Volume: |
34 |
| Issue: |
3 |
| Pages: |
743-751 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
DeBenedette MA |
| Year: |
1995 |
| Journal: |
J Exp Med |
| Title: |
Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP. |
| Volume: |
181 |
| Issue: |
3 |
| Pages: |
985-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim DK |
| Year: |
2009 |
| Journal: |
Eur J Immunol |
| Title: |
CD137 ligand-mediated reverse signals increase cell viability and cytokine expression in murine myeloid cells: involvement of mTOR/p70S6 kinase and Akt. |
| Volume: |
39 |
| Issue: |
9 |
| Pages: |
2617-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baessler T |
| Year: |
2010 |
| Journal: |
Blood |
| Title: |
CD137 ligand mediates opposite effects in human and mouse NK cells and impairs NK-cell reactivity against human acute myeloid leukemia cells. |
| Volume: |
115 |
| Issue: |
15 |
| Pages: |
3058-69 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543876 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549435 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Heart |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543876 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549435 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Lung |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543876 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549435 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Liver |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543876 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549435 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Kidney |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543876 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549435 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Spleen |
| Detected: |
false |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543876 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3511228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549435 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Fat |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543876 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549435 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Brain |
| Detected: |
false |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543876 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549435 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Femur |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543876 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-11-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1768128 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7549435 |
| Age: |
postnatal week 10 |
| Image: |
1 |
|
| Specimen Label: |
Calvaria |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_01 |
|
| Specimen Label: |
euxassay_011811_01 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_02 |
|
| Specimen Label: |
euxassay_011811_02 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_03 |
|
| Specimen Label: |
euxassay_011811_03 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_14 |
|
| Specimen Label: |
euxassay_011811_14 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_15 |
|
| Specimen Label: |
euxassay_011811_15 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_16 |
|
| Specimen Label: |
euxassay_011811_16 |
| Detected: |
true |
| Specimen Num: |
16 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_17 |
|
| Specimen Label: |
euxassay_011811_17 |
| Detected: |
true |
| Specimen Num: |
17 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1914323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_18 |
|
| Specimen Label: |
euxassay_011811_18 |
| Detected: |
true |
| Specimen Num: |
18 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1749023 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_06 |
|
| Specimen Label: |
euxassay_011811_06 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1749023 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_12 |
|
| Specimen Label: |
euxassay_011811_12 |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1763523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_02 |
|
| Specimen Label: |
euxassay_011811_02 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1763523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_03 |
|
| Specimen Label: |
euxassay_011811_03 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1763523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_04 |
|
| Specimen Label: |
euxassay_011811_04 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1763523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_05 |
|
| Specimen Label: |
euxassay_011811_05 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1763523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_06 |
|
| Specimen Label: |
euxassay_011811_06 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1763523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_07 |
|
| Specimen Label: |
euxassay_011811_07 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1763523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_08 |
|
| Specimen Label: |
euxassay_011811_08 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1763523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_10 |
|
| Specimen Label: |
euxassay_011811_10 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1763523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_11 |
|
| Specimen Label: |
euxassay_011811_11 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1763523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_12 |
|
| Specimen Label: |
euxassay_011811_12 |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1763523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_13 |
|
| Specimen Label: |
euxassay_011811_13 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1763523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_14 |
|
| Specimen Label: |
euxassay_011811_14 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1763523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_15 |
|
| Specimen Label: |
euxassay_011811_15 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1910623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_01 |
|
| Specimen Label: |
euxassay_011811_01 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1910623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_02 |
|
| Specimen Label: |
euxassay_011811_02 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1910623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_17 |
|
| Specimen Label: |
euxassay_011811_17 |
| Detected: |
true |
| Specimen Num: |
17 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1910623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_18 |
|
| Specimen Label: |
euxassay_011811_18 |
| Detected: |
true |
| Specimen Num: |
18 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1910623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_19 |
|
| Specimen Label: |
euxassay_011811_19 |
| Detected: |
true |
| Specimen Num: |
19 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1910623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_20 |
|
| Specimen Label: |
euxassay_011811_20 |
| Detected: |
true |
| Specimen Num: |
20 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1871923 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_02 |
|
| Specimen Label: |
euxassay_011811_02 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1871923 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_03 |
|
| Specimen Label: |
euxassay_011811_03 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1871923 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_04 |
|
| Specimen Label: |
euxassay_011811_04 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1871923 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_14 |
|
| Specimen Label: |
euxassay_011811_14 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1871923 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_15 |
|
| Specimen Label: |
euxassay_011811_15 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1871923 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_16 |
|
| Specimen Label: |
euxassay_011811_16 |
| Detected: |
true |
| Specimen Num: |
16 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1871923 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_17 |
|
| Specimen Label: |
euxassay_011811_17 |
| Detected: |
true |
| Specimen Num: |
17 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1871923 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_18 |
|
| Specimen Label: |
euxassay_011811_18 |
| Detected: |
true |
| Specimen Num: |
18 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1871923 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_19 |
|
| Specimen Label: |
euxassay_011811_19 |
| Detected: |
true |
| Specimen Num: |
19 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1872223 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_01 |
|
| Specimen Label: |
euxassay_011811_01 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1872223 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_17 |
|
| Specimen Label: |
euxassay_011811_17 |
| Detected: |
true |
| Specimen Num: |
17 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1870623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_06 |
|
| Specimen Label: |
euxassay_011811_06 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1870623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_07 |
|
| Specimen Label: |
euxassay_011811_07 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1870623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_08 |
|
| Specimen Label: |
euxassay_011811_08 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4424125 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1870623 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828849 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_011811_09 |
|
| Specimen Label: |
euxassay_011811_09 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McKenzie DR |
| Year: |
2022 |
| Journal: |
Nat Immunol |
| Title: |
Normality sensing licenses local T cells for innate-like tissue surveillance. |
| Volume: |
23 |
| Issue: |
3 |
| Pages: |
411-422 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mak A |
| Year: |
2019 |
| Journal: |
Front Immunol |
| Title: |
Deletion of CD137 Ligand Exacerbates Renal and Cutaneous but Alleviates Cerebral Manifestations in Lupus. |
| Volume: |
10 |
|
| Pages: |
1411 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tan JT |
| Year: |
1999 |
| Journal: |
J Immunol |
| Title: |
4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses. |
| Volume: |
163 |
| Issue: |
9 |
| Pages: |
4859-68 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bertram EM |
| Year: |
2002 |
| Journal: |
J Immunol |
| Title: |
Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection. |
| Volume: |
168 |
| Issue: |
8 |
| Pages: |
3777-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
DeBenedette MA |
| Year: |
1999 |
| Journal: |
J Immunol |
| Title: |
Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus. |
| Volume: |
163 |
| Issue: |
9 |
| Pages: |
4833-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shin SM |
| Year: |
2007 |
| Journal: |
J Leukoc Biol |
| Title: |
4-1BB triggers IL-13 production from T cells to limit the polarized, Th1-mediated inflammation. |
| Volume: |
81 |
| Issue: |
6 |
| Pages: |
1455-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Niu L |
| Year: |
2007 |
| Journal: |
J Immunol |
| Title: |
Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice. |
| Volume: |
178 |
| Issue: |
7 |
| Pages: |
4194-213 |
|
•
•
•
•
•
|